... month ofthe year exceeds the maximum ofthe other years 136 Figure 6.6 The cumulative amount by which the horizontal global radiation for each month ofthe year falls below the minimum ofthe ... the minimum ofthe other years 134 Figure 6.2 The number of hourly instances that the horizontal global radiation for each month ofthe year exceeds the maximum or falls below the minimum of ... minimum ofthe other year 134 Figure 6.3 The cumulative amount by which the dry bulb temperature for each month ofthe year exceeds the maximum ofthe other years 135 Figure 6.4 The cumulative...
... Jersey, the first asphaltic roadway was constructed (Microsoft Encarta, 2004) The use of asphalt and the popularity ofthe automobile triggered the dawn of design methods The aim of these design ... thickness of subgrade soil support in flexible pavement This is well noticeable when thesoil support values are low, especially in the case ofthe Illinois soils “Recognition ofthe importance ofthe ... fulfillment ofthe requirements forThe Master of Science Degree in Civil Engineering The University of Toledo December 2004 Subgrade soil plays a very important role in the construction of roadways Before...
... accounted for in thesimulationThe analytical modelsof Verrier et al [14] and Chevalet [3] will then be described, each corresponding to a different choice of hypotheses forthe algebraic formalization ... used forthe MC simulations 4.1 Effect of number of loci Table I presents the values of RV[30] provided by the three models when ] [30 decreasing the number of loci L (with multiallelic loci in the ... in the case of 1000, 100 and 10 multiallelic loci controlling the selected trait, in order to check the effect of linkage on thepredictionof genetic variance over time in the FFM The effect of...
... allow forthe level of adherence to drug therapy regimes to be monitored Additionally, such an analysis would facilitate a more accurate assessment ofthe progression ofthe patient in terms of their ... physicians The utilisation of VL data, with knowledge ofthe presence (or lack) of drug resistant mutations, should allow clinicians to form a more accurate picture ofthe adherence levels of their ... although there is some concern over the long term efficacy when the information content is low Page of (page number not for citation purposes) AIDS Research and Therapy 2009, 6:9 The ability of patients...
... due to the developmental stage ofthe embryos rather than the number of embryos (Horne et al 1983) A practical consequence might be to sample animals on a specified number of days from the last ... relation to the onset of oestrus Acknowledgements The authors wish to express their gratitude to the owners and employees for valuable help during collection of blood and data, as well as to the satellite ... Multivariate models were run with the values of E1S on days 24 and 28, respectively, as response variables In these modelsthe explanatory variables were the fixed effect of parity and regression on...
... ∪ σint to denote the partition ofthe base pairs ofthe first sequence, σ1, the base pairs ofthe second sequence, σ2, and the interacting base pairs, σint Furthermore, forthe partial structure ... details, see [25] The PETfold score is the sum ofthe evolutionary accuracy values plus the average sum ofthe thermodynamic accuracy values Forthe evolutionary part, we compute the expected accuracy ... secondary structure predictionofthe OxyS-fhlA complex, i.e., the secondary structures of OxyS and fhlA and the interaction between them, as predicted by our algorithm The result oftheprediction without...
... development over the past 30 years The bottom half ofthe timeline denotes the emergence of key humanized mouse modelsThe top half ofthe timeline denotes the application ofthemodels to HIV-1 ... model Here, we focus on the development of each of these modelsforthe study of human retroviral infection, i.e., with HIV-1 and HTLV-1 The comparison of all of these models in historical context, ... Comparison of animal modelsforthe study of retroviral infection The identification of HIV-1 as the causative agent of AIDS was followed only a year later by the recruitment of chimpanzees for the...
... results highlight the utility of a new panel of biochemical markers (ST) forthepredictionof steatosis of different origins A cut-off of 0.30 had 90% sensibility and a cut-off of 0.72 had 90% ... Rufat P, Degos F: Practices of liver biopsy in France: Results of a prospective nationwide survey Forthe Group of Epidemiology ofthe French Association forthe Study ofthe Liver (AFEF) Hepatology ... the severity of steatosis, is illustrated in Figure forthe training and validation groups The diagnostic values of ST, GGT and ALT according to cutoffs are shown in Table Forthe diagnosis of...
... detailed description ofthe procedure forthe validation ofthe model Click here File model model A detailed description ofthe procedure forthe validation ofthe Additionalfor file Acknowledgements ... understanding the regulation ofthe expression and release of these mediators is crucial for understanding the course ofthe inflammation process Here we propose models that derive the responses of seven ... list of all significant predictors) During this phase, it is also required that the signs ofthe coefficients ofthe predictors in the minimal model be the same as the sign ofthe coefficients of...
... to the matrix X L (L being the iteration number), in the order ofthe highest to the lowest sensitivity To make the adjustment ofthe net influence of each ofthe remaining parameters on the ... represents the actual value ofthe parameter as determined in [12] The remaining bars represent the estimated values ofthe corresponding parameter, from left to right, forthe UKF, the GA and the NLSQ ... based on the model structure and the measurement data One ofthe benefits in integrating estimation and identifiability is the reuse ofthe variance generated by the UKF forthe step size in the calculation...
... uniformly from (0, Vmax ] Table shows the values of all parameters used in thesimulationThe following metrics are computed to evaluate the impact of each mobility model on the performance ofthe ... estimate the cost of introducing the new protocol (2) The goodput ofthe TCP is the number of sequenced bits that a TCP receiver receives per unit of time This measure will show the effectiveness ofthe ... in terms of number of hops for RPGM because ofthe strict movements of nodes On the other hand, for FRW and MAN, the higher the node speed, the higher the tendency for short connection (≤3) This...
... is the number of cells strictly left of c in the diagram of λ (3) The leg of c, denoted l(c), is the number of cells strictly below c in the diagram of λ (4) The coleg of c, denoted l (c), is the ... invalid in the other.) This lemma, together with the discussion preceding it, completes the proof of formula (18) We leave to the reader the task of showing that this formula reduces to formula ... journal of combinatorics 11 (2004), #R68 c Figure 1: Diagram of a partition (1) The arm of c, denoted a(c), is the number of cells strictly right of c in the diagram of λ (2) The coarm of c, denoted...
... represent 1% ofthe population, have a risk of 30% to develop prostate cancer over the next years The incidence of disease in the population of 60-year-old men is about 2% Thus, the size ofthe group ... supported by the Centre for Medical Systems Biology (CMSB) in the framework ofthe Netherlands Genomics Initiative (NGI) Furthermore, this project was sponsored by the VIDI grant ofthe Netherlands ... the impact of genotype frequencies and ORs on the overall discriminative accuracy of genetic risk models, we assessed the AUC [18] Next, to assess the predictive performance of genetic risk models...
... procedures, the Institutional Board on the Ethics of Clinical Studies waived the need for informed consent Further details on the setting ofthe study are described elsewhere [9,10] Analysis of risk ... the ICU Overall, in 214 ofthe 1,876 admissions (11.4%) the patient died in the ICU More details of risk factors and outcomes are shown in Table Analysis of risk factors forthe acquisition of ... risk of dying (model 2) However, these patients stay longer in the ICU There are two possible explanations for this: firstly, there is an effect independent of whether they acquire NP during their...
... accuracy of prognostic modelsforthe early care of trauma patients Conclusions This systematic review located and appraised the quality of five prognostic modelsforthe early care of trauma ... care of trauma patients The majority ofmodels were developed in cohorts of trauma patients from the 80’s All except one ofthemodels were developed in populations from high-income countries The ... the clinical credibility ofthe model remained unevaluated, and none ofthemodels were tested in a randomised clinical trial Discussion This systematic review located prognostic modelsfor the...
... densities or products thereof may be specified forthe prior density p(ϕ) on ϕ, depending, again, on the number of sets of random effects and whether there are any covariances thereof [21] Finally, ... The objectives of this study were to validate MCMC inference ofthe CT generalized linear mixed (sire) model via a simulation study and to compare the fit of this model with the CP model forthe ... al The generation of individual elements θj , j = 1, 2, , p + q or blocks thereof of θ from their respective FCD is straightforward using the strategy presented by Wang et al [48] The FCD of...
... is the range ofthe amorphous Pearson profile Rpb is the range ofthe channeled Pearson profile σ a is the standard deviation ofthe amorphous Pearson profile σ b is the standard deviation ofthe ... channeled Pearson profile γ a is the skewness ofthe amorphous Pearson profile γ b is the skewness ofthe channeled Pearson profile β a is the kurtosis ofthe amorphous Pearson profile - 28 - b β ... amorphous Pearson profiles, respectively, ratio is the ratio ofthe dose ofthe amorphous profile to the total dose and u is the coordinate along the depth A final profile will take the shape as illustrated...
... on the prevalence in the population, and more reflective ofthe test itself, lessening the impact of any unique features ofthe VA population Moreover, we might expect that the PPV and NPV ofthe ... NC) Results The characteristics ofthe VARA participants measured at the start of each treatment episode were evaluated Because the characteristics of VARA patients at the start of non-biologic ... contrast to other RA therapies where the drugs are typically discontinued if they are not effective Because of similarities in both the descriptive characteristics ofthe study populations of biologic...
... attempted for three SPT patients in whom the mass was located in the portion of body or tail ofthe pancreas For tumors of SPT located in the neck and body ofthe pancreas, resection ofthe midportion ... midportion ofthe pancreas and the mass with preserving the rim ofthe head and tail portion can be achieved However, forthe patient in whom the mass was located within the head ofthe pancreas, ... 311 Fig The CT scan indicated the typical internal or capsular calcification in the SPT Once the diagnosis of SPT is made, surgery is the first choice of treatment, since other adjuvant therapies,...
... 100% relief of their pain in 86% ofthe patients with a median relief period of months The range of relief varied from zero days to up to 13 months forthe facet injection group None ofthe lumbar ... median period of pain relief being months The range of relief forthe radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure Ofthe 14 patients ... that the direct visualization ofthe joint allows better de-innervation ofthe joint and removal ofthe entire end-plate receptors that adhere to the bone and capsular tissue Limitations of the...