schematic diagram of the genetic algorithm based descriptor selection method
Machine learning approach in pharmacokinetics and toxicity prediction
Ngày tải lên :
15/09/2015, 17:10
... 26 Figure 2.2 Schematic diagram of the genetic algorithm- based descriptor selection method 38 Figure 2.3 Schematic diagram illustrating the process of the prediction of compounds with ... optimization of the essential parameters of the machine learning methods and the selection of relevant descriptor subsets are conducted simultaneously The optimum set of parameters and descriptor ... process, correct the imbalances and brings about the normal functioning of the body Pharmacokinetics is the study of the time course of a drug within the body and incorporates the processes of absorption,...
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Polystyrene (PS) waste plastic conversion into aviation /kerosene category of fuel by using fractional column distillation process
Ngày tải lên :
05/09/2013, 15:28
... Journal of Energy and Environment (IJEE), Volume 3, Issue 6, 2012, pp.871-880 polyethylene and most of them is in the form of containers and packaging materials The extent of conversion of plastics ... [4-7] An interesting method of polymers utilization is cracking, similar to the visbreaking of vacuum residue [8] or catalytic cracking of vacuum gas oil (VGO) in the presence of various zeolites ... acknowledges the support of Dr Karin Kaufman, the founder and sole owner of Natural State Research, Inc The authors also acknowledge the valuable contributions NSR laboratory team members during the preparation...
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ANALYSIS OF NAMES OF ORGANIC CHEMICAL COMPOUNDS BY USING PARSER COMBINATORS AND THE GENERATIVE LEXICON THEORY doc
Ngày tải lên :
05/03/2014, 20:20
... are assigned the number of the carbon to which they are attached In Figure 2, the substituent CH3 is assigned the number • The name of the compound is now composed of the name of the main chain ... way, the Generative Lexicon Theory is used to solve ambiguity problems based on the type constraints expressed in the qualia structures of the lexical items The relevance of the types in the process ... at the end of the process, when the system tries to apply the qualia structure of the later name to the radical 4-ethyl (type E4) However, E4 does not unify with the type {TOP_3 (otherwise, the...
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assessing damage of flood by using alos data in thua thien - hue province - vietnam
Ngày tải lên :
26/03/2014, 14:07
... Province The method of the study shows in the Figure Fig Flowchart of the method Fig The study area RESULTS 3.1 Flooded area of landuse/cover types The map of landuse/cover was overlaid on the map of ... processing, the map of flooded area from PALSAR and DEM from the PRISM image Use the overlay function in the GIS tool to calculate and map the flooded levels of landuse/cover types in the Thua Thien ... correction of DEM result must know the distribution of landuse/cover types to correct DEM For example, in the areas with dense forest distribution of 20m of high trees, the spectrum of light to...
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Optimization of Cost by Using 7 QC Tools docx
Ngày tải lên :
10/07/2014, 23:21
... has on another A common diagram of this type usually displays points representing the observed value of one variable corresponding to the value of another variable Figure 5: Scatter Diagram Control ... by the fans put in the shop floor & get accumulated every where In-due course of time this dust get accumulated on the BT 40 taper of the tool holder & causes to have run out in the tool As the ... increase the bore to become oversize Result: Valid cause for the problem Step 5:- counter measure: Short term: • Instruction was given to all the operators & the officials about the valid cause of the...
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A computational study of chiral separation of tryptophan by using cyclodextrin
Ngày tải lên :
15/09/2015, 22:51
... process The selection of the separation methods depends on the properties of chiral molecules and the feasibility as well as the cost of the separation process 15 1.4 Motivations and Objectives In the ... through the chiral film slower than the other, and, therefore, differing levels of displacements of the two enantiomers are observed as a function of time Chapter describes the advantages of and the ... in the chiral discrimination of the enantiomers of the solute molecule The typical CSPs in this group contain crown ethers and cyclodextrin [20] Crown ethers are synthetic macrocyclic polyethers;...
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Tài liệu Báo cáo khoa học: Transcriptional upregulation of inflammatory cytokines in human intestinal epithelial cells following Vibrio cholerae infection pptx
Ngày tải lên :
18/02/2014, 16:20
... immune system, as they provide the underlying mucosa with the first signals of an infection [16] As the intestinal mucosal epithelial surface forms the first barrier encountered by the enteric pathogen ... induces epithelial cytokine responses The poor response of LPS can be explained by the lack of CD14 and toll-like receptor on epithelial cells [31] To determine whether CT is a potent inducer of cytokines, ... role in promoting the expression of cytokines through interaction with other cofactors such as CREB 4638 within the gene promoter regions [15] To determine whether the upregulation of proinflammatory...
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Báo cáo Y học: Purification and characterization of novel chondroitin ABC and AC lyases from Bacteroides stercoris HJ-15, a human intestinal anaerobic bacterium pptx
Ngày tải lên :
31/03/2014, 23:20
... buffer, pH 7.0 and the column was washed with 300 mL of the same buffer (the fraction passing through the column without binding was used for the purification of chondroitin AC lyase) Then CM-Sephadex ... (data not shown), consistent with their pI values of 7.9–8.3 The amino-acid compositions of the chondroitin lyases were similar, but not identical The pI values of the purified chondroitin ABC and ... solution was added and the cuvette was gently inverted twice to mix the contents It was then immediately placed in the warmed holder of spectrophotometer and the change of absorbance at 232 nm...
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Báo cáo y học: " Prediction of viral microRNA precursors based on human microRNA precursor sequence and structural features" pot
Ngày tải lên :
12/08/2014, 04:20
... validated a subset of the prediction [10,11] These provide evidence about the genome-wide applicability and reliability of our method for ab-initio prediction of microRNA precursors The method is fast ... 64.34 The numbers denote the total number of positive predictions The number in brackets following the organism name denotes the total number of entries in miRbase and that following the number of ... Illustrative summary of the process flow in the presented method for microRNA precursor prediction The lines in red denote the process flow in prediction while the lines in dark blue denote the process...
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Báo cáo sinh học: " Effects of the number of markers per haplotype and clustering of haplotypes on the accuracy of QTL mapping and prediction of genomic breeding values" pot
Ngày tải lên :
14/08/2014, 13:21
... matrix by using a submatrix of the IBD matrix selected based on the eigenvalues of the IBD matrix This method also substantially reduces the rank of the IBD matrix, while the predicted QTL position ... size The aim of this paper was to investigate the effect of the number of surrounding marker alleles (window size) included in base haplotypes and the effect of clustering of base haplotypes based ... 7th, and 10th and 11th marker When the number of markers was insufficient to the 'left' or the 'right' of a QTL position, more markers from the other side of the putative QTL P( v j |s V )×Prj...
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Báo cáo sinh học: " Impacts of both reference population size and inclusion of a residual polygenic effect on the accuracy of genomic prediction" potx
Ngày tải lên :
14/08/2014, 13:21
... constant, regardless of the level of residual polygenic variance Figure shows the influence of the sires’ EBV on the DGV of validation bulls The R2 values of the regression of DGV on the sires’ EBV ... increased to 20% of the total genetic variance, the R2 value between the DGV of the son and the EBV of the sire dropped below 0.20 In contrast to DGV, corresponding R values for the sum of DGV and RPG ... information was calculated as the difference between the realised reliability of the pedigree -based EBV and the combined GEBV of the validation bulls Scenarios to study the impact of the residual polygenic...
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The transference of meaning through class of words denoting parts of the human body in english and vietnames
Ngày tải lên :
18/12/2013, 21:45
... earth The hand of a child - The hand of a lock The heart of a man - The heart of a matter 37 The tongue of a man - The tongue of a shoe The tooth of a person - The tooth of a comb The head of a ... hands of a farm 13 The heel of a person - The heel of the hand 14 One's leg - The leg of a trip 15 One's brain - The brains of a family 16 The bosom of a person - The bosom of the church 17 The ... part There are various types of similarity: - The similarity of shape E.g: The teeth of a saw, the head of a cabbage - The similarity of position E.g: The tail of procession - The similarity of...
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Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx
Ngày tải lên :
18/02/2014, 11:20
... powerful method, and several algorithms have been developed recently [4–7] The major drawback of these analyses is the lack of information regarding the activity or loss of activity of the target ... advantage of p53 mutation analysis, and a unique feature of this database, is the availability of the residual activity of the majority of p53 missense mutants The biological activity of mutant ... the cross indicates the cut-off value used in PREDMUT The limit between the classes was set to the activity value of 25%, because this value was observed to be a natural divider of the data The...
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Tài liệu Báo cáo khoa học: Allosteric modulation of myristate and Mn(III)heme binding to human serum albumin Optical and NMR spectroscopy characterization pptx
Ngày tải lên :
20/02/2014, 02:22
... subtracting the width of the H217 O signal in the presence of HSA from the width of the H217 O signal in the presence of Mn(III)heme–HSA at different myristate concentrations DW values are related to the ... in the case of Fe(III)heme–HSA Two hypotheses should be taken into consideration: either the absence of water molecules in the coordination sphere of the metal ion, or the presence of one water ... Mn(III)heme were taken and the binding isotherm was analyzed by plotting the difference of absorbance between the maximum and the minimum of the two-signed difference spectra against the protein concentration...
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Tài liệu Báo cáo khoa học: "Evaluating the Accuracy of an Unlexicalized Statistical Parser on the PARC DepBank" docx
Ngày tải lên :
20/02/2014, 12:20
... mation in the PoS tags and by the need to balance depth of analysis against the size of the derivation space On the Susanne corpus, the geometric mean of the number of analyses for a sentence of length ... version of the XLE parser to the publically available version of Collins’ parser One fifth of DepBank is held out to optimize the speed and accuracy of the three systems They conclude from the results ... (see Briscoe, 2006 for further details) The lexical categories of the grammar consist of feature -based descriptions of the 149 PoS tags and 13 punctuation tags (a subset of the CLAWS tagset, see...
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Tài liệu Báo cáo khoa học: Role of cleavage and shedding in human thyrotropin receptor function and trafficking pdf
Ngày tải lên :
21/02/2014, 00:20
... black The percentage of identity of the different extracellular regions of the TSHR to the corresponding regions of the human LH receptor are indicated above The E3 region (residues 289–385) is the ... with the wild-type receptor (Fig 4B) We wondered whether shedding of the ectodomain would modify the trafficking of the receptor Therefore, we studied the comparative internalization of the wild-type ... sequential and leads to the processive digestion of the specific extracellular region of the TSHR The enzyme involved in the maturation of the TSHR shares similarities with the ADAM (A Disintegrin...
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Báo cáo " Assessment of the influence of interpolation techniques on the accuracy of digital elevation model " potx
Ngày tải lên :
05/03/2014, 16:20
... point of interest to the sample point i ; and the power p controls the significance of sample points to the interpolated values, based on their distance to the output point The higher the power, the ... Compute RMSE of DEM Fig The workflow for assessing the influence of interpolation technique on the accuracy of DEM by using ArcGIS software 2.2 The workflow The assessment of influence of interpolation ... weight, the smoother the output surface For the tension spline, the higher the weight, the coarser the output surface More detailed information about the spline interpolation can be found in [6] - The...
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Báo cáo khoa học: Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating fibrinolysis doc
Ngày tải lên :
07/03/2014, 12:20
... stability of CPU’s activity, especially the YQ mutant Following the first round of FINDTM treatment, 50% of the mutants with improved thermal stability of their activity appeared to bear mutations in the ... connected to an increased thermostability of the protein itself, we monitored the thermal unfolding of WT and YQ proCPU-CHis Compared with the WT, the midpoint temperature (Tm) of the protein-unfolding ... the mutations in the YQ proCPU did not alter the affinity of the carboxypeptidase for synthetic 784 Fig Thermal unfolding of WT proCPU-CHis and YQ proCPUCHis The thermal unfolding of WT and YQ proCPU-CHis...
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