role of vegetables and fruit in prevention
Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
... charged amino acid side chains, R397 and R120, are also involved in fosfomycin binding, and in view of the multitude of interactions, it was assumed that deletion of a single interaction would not ... chain of K22 participates in fosfomycin binding, thus providing a rationale for the loss of fosfomycin binding to the K22V and K22E mutant proteins However, two other positively charged amino ... enthalpies of binding and stoichiometries were determined from the binding isotherm by fitting a : binding model to the data using the software provided by the manufacturer Results Reaction of fosfomycin...
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Tài liệu Báo cáo khoa học: Role of cleavage and shedding in human thyrotropin receptor function and trafficking pdf
... proper folding, trafficking and ligand-mediated signaling but not for ligand binding [37,40] The complete loss in the constitutive activity of the Ó FEBS 2003 Role of cleavage and shedding in TSHR ... periods of times (0–60 min) at 37 °C The concentration of the biotinylated Ig remaining on the cell surface was then quantified by measuring the binding of [125I]Streptavidin In the absence of bTSH, ... five amino acids of the extracellular domain and devoid of any tag was not functional [27], while a mutant containing four amino acids of the ectodomain and including a rhodopsine tag was found...
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Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt
... vector and overexpressed in Escherichia coli BL21(DE3) The C-terminally His6-tagged and N-terminally thioredoxin-fused protein was purified, yielding 4.4 mgÆL)1 of culture The identity of the protein ... motif present in DptF is GLDSV, indicating that this putative ACP domain is one of the few ACPs in which valine replaces isoleucine (I) or leucine (L) in the conserved sequence To determine whether ... partner of DptE, we expressed dptF using the pQTev vector in E coli and purified the resulting ACP as an N-terminal His7 fusion protein (Fig 3) with a yield of 9.5 mgÆL)1 of culture The identity of...
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The Role of Savings and Wealth in Reducing ―Wilt‖ between Expectations and College Attendance pdf
... or less are defined as ―uncertain.‖ There are 120 youth in this sample, and 453 in the combined (certain and uncertain) sample.5 Variables In this section, variables of interest and control variables ... important for explaining wilt In the case of income, youth living in low-income households experience higher levels of wilt (45%) than youth living in either modest-income (35%) or high-income (23%) ... of accumulating school savings may have effects apart from financing school Conley (2001) finds that a doubling of net worth results in an 8.3% increase in the probability of attending college...
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Báo cáo khoa học: Tertiary structure in 7.9 M guanidinium chloride ) the role of Glu53 and Asp287 in Pyrococcus furiosus endo-b-1,3-glucanase pot
... role in protein stability [8], and their involvement in interactions with cations offers new perspective in the analysis of the contribution of ions as cofactors in protein folding [38] and in ... presence of one or two potential binding sites for metals and two pairs of negatively charged amino acid residues have been assumed to be involved in calcium binding: Glu53 and Asp287, and Glu239 and ... decreases in 7.9 m GdmCl and increases in native conditions Discussion The results obtained with pfLamA mutant forms indicate that residues Glu53 and Asp287 are involved in calcium binding, in accordance...
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Báo cáo khoa học: The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein ppt
... ADAM10 and TACE are involved in the shedding of APP, neither ADAM is involved in the shedding of ACE Furthermore we show that APMA can distinguish between the shedding of ACE and APP Materials and ... would appear that ADAM10 and TACE are not critically involved in the shedding of ACE APMA has been reported to induce the shedding of a number of protein ectodomains, including APP, from CHO cells ... cells again underlines that TACE is not critically involved in APP shedding, at least in this cell line Although we failed to see an increase in the shedding of APP upon incubation of the cells...
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báo cáo sinh học:" The role of nurses and midwives in polio eradication and measles control activities: a survey in Sudan and Zambia" pdf
... clients; continuously assessing and monitoring health needs and responses to interventions; advocacy and education of clients and communities; and delivering and coordinating health services across ... other hand, in Zambia, nurses and midwives were involved in the full range of functions for SIAs and AFP surveillance Survey of nurses and midwives working at health facilities Routine tasks and ... spent more time dealing with diseases related to HIV infection, including HIV counselling - including prevention of mother to child transmission - referral of patients and administrative tasks...
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Báo cáo khoa học: "The role of photoperiod and temperature in the induction and the release of dormancy in Pinus sylvestris L. seedlings" potx
... breaking treatments of and wk had a dramatic influence, hastening the tilushing rate, especially in the plants with lowest degree of dormancy In Fig the same reactions to temperature and break of ... the chilling requirement to break winter dormancy in Scots pine has been stressed (e.g., Wareing, 1951; Vegis, 1965; Sarvas, 1974) In the following,I will use the working definition of dormancy ... 48-57 Ingestad T (1979) Mineral nutrient requiresylvestris and Picea abies seed- ments of Pinus lings Physiol Plant 45, 373-380 Kupila-Ahvenniem S (1985) Wintertime changes in the fine structure and...
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Báo cáo y học: "The role of pleiotrophin and β-catenin in fetal lung development" doc
... The binding of PTN with syndecan-3 induces neurite outgrowth of embryonic neurons [67] Heparitinase, which cleaves the heparin sulfate chain and disrupts the binding of PTN, inhibits PTN-induced ... are also involved in the epithelial-mesenchymal interactions and play essential roles in lung development [31] Pleiotrophin Pleiotrophin (PTN) is an 18 kDa heparin-binding cytokine and shares ... for ligand binding [73] The extracellular part of RPTPβ/ζ also possesses a carbonic anhydrase-like domain, a fibronectin III-like domain, and a glycine-serine rich domain [73] These domains interact...
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Báo cáo y học: "Role of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vectors" pptx
... against oral challenge with SIVmac251 indicating that ADCC is not a main mechanism in reducing infection [29] This is in contrast to recently reported findings which indicate that ADCC or the interaction ... and viral load during peak viremia was observed at least within the individual groups of vaccinated monkeys (Figure 3) During the chronic phase of infection, sera of all vaccinated macaques induced ... performed in double) from the vaccinated, and infected animals were incubated with SIVmac251 (160 ng/ml p27, TCID50 = 5.9 × 105log) for 30 minutes at 4°C in order to allow for the binding of the induced...
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Báo cáo y học: "The role of ATP and adenosine in the control of hepatic blood flow in the rabbit liver in vivo" pps
... prosthesis inserted into the portal vein and the inferior vena cava of the in vivo rabbit model Figure Diagram of silastic H-shaped prosthesis inserted into the portal vein and the inferior vena cava of ... in the degree of inhibition of HA responses by 8-SPT between intra-arterial and intra-portal injection of ATP despite a longer lag-time between injection and response following intra-portal injection ... Figure of intra-portal injection of (a) ATP and (b) adenosine on changes in hepatic arterial flow (∆ HAF) in vivo The effect The effect of intra-portal injection of (a) ATP and (b) adenosine on...
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Tasks in action in Vietnamese EFL high school classrooms- The role of rehearsal and performance in teaching and learning through oral tasks
... time and trust I sincerely thank the Department of Education and Training, the Head of the school and teaching staff of the school back home in Vietnam for their support and encouragement during ... teacher thinking underlying the way they design and implement tasks, and student engagement in tasks and learning outcomes, an important relationship given the tandem nature of teaching and learning ... from both teaching and learning Furthermore, existing research into general EFL instruction in Vietnam, mainly in university settings, has shown a lack of meaningful communication in the classroom...
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Role of PLD and SPHK in TNFa induced signaling and inflammatory responses
... the need in understanding the role and interaction of PLD with other TNFα signaling mediators PKC The role of PKC (Protein Kinase C) in TNFα−induced signaling and responses in a variety of cells ... inflammatory role of PLD in TNFα-induced signaling and responses Recent studies were more conclusive and detailed about the role of PLD in TNFα signaling The apoptotic and survival role of PLD in general ... coupling of PLD1 to TNFα signaling and responses in human monocytes Furthermore, we validated the in vivo role of PLD1 and SphK1 in TNFα induced peritonitis in BALB/c mice using short interfering...
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Establishment of cell polarity in zebrafish role of staufen and GRB2 in cell migration
... vegetal cortex in Xenopus oocytes, Vg1 RNA binding protein (RBP) (indigo) with Staufen (yellow) is loaded into microtubules (red) using adaptor proteins and motor proteins Kinesin I and II Vg1 mRNA ... localized in the oocyte, but it is not clear how they are achieved 21 1.6 RNA binding proteins in mRNA localization Double stranded RNA binding (ds RBD) proteins interact with as minimum of 11 bp of ... compartment and mainly expressed in the brain (Duchaine et al., 2002) Stau particles in RNA containing granules co-localize with microtubules in dendrites of hippocampal neurons, suggesting its role in...
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The role of cyr61 and LASP1 in growth and metastasis of human hepatocellular carcinoma
... and Marcantonio 2006) For instance, the integrin-binding proteins paxillin and talin recruit focal adhesion kinase (FAK) and vinculin to focal contacts (Sastry and Burridge 2000; Calderwood and ... that the LIM motif defined a specific zinc-binding protein domain There are eight most highly conserved residues functioning in binding to zinc, establishing a tandem zinc-finger topology (Michelsen ... actin binding sites and a C-terminal src homology SH3 domain (Figure 1.3) The actin binding domain is believed to be functioning as a mediator for protein-protein interactions between Lasp1 and...
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Role of calpain and cofilin in apoptosis regulation
... Silencing of cofilin expression using cofilin siRNA Figure 5.2.2 Lack of cytochrome c release and apoptotic morphology in cofilin knockdown cells Figure 5.2.3 Depletion of endogenous cofilin protein inhibits ... localisation of cofilin is independent on its actin-binding activity Figure 5.7.2 Mitochondrial-localised cofilin mutant-induced apoptosis is dependent on the actin-binding domain Figure 5.7.3 Cofilin ... blocking cofilin translocation Figure 5.4.3 Cofilin S3D blocks translocation of endogenous cofilin Figure 5.5 Mitochondrial-localised cofilin induces apoptosis Figure 5.6.1 Cofilin15-166, cofilin15-30/106-166...
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Grounding cognition the role of perception and action in memory, language, and thinking DIANE p
... dynamic/kinematic information relating to the interaction of the objects, including ideas of support, containment and locational control One Example of a Functional In uence One example of functional ... The interaction between cognition and spatial and action processes, (2) understanding emotional and abstract concepts, (3) the grounding of grammar in embodied experiences, (4) examining the role ... bicycle In the case of the rock, we quickly derive the affordance of stopping or of removing the obstacle In the case of the bicycle, the handle may afford the action of grasping it, the seat of sitting...
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Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
... shown) Role of PKA in the mitochondrial targeting of CYP2E1 The role of PKA in mitochondrial targeting of CYP2E1 was investigated using two approaches The first approach involved measuring the ... The intramitochondrial localization of CYPs and their topologies were studied using a combination of treatment with trypsin, treatment with digitonin plus trypsin, and extraction with alkaline ... subjected to alkaline Na2CO3 extraction In (A), increasing concentrations of trypsin (0–100 lgÆmL)1) were used, and in (B), (D) and (E), a fixed concentration (50 lgÆmg)1) of trypsin were used Fifty...
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Tài liệu Báo cáo khoa học: Unfolding of human proinsulin Intermediates and possible role of its C-peptide in folding/unfolding pptx
... (preproinsulin) and folded as proinsulin, in which a connecting peptide of 35 residues links the C terminus of the B chain and N terminus of the A chain After digestion by a specific set of protein ... enzymes in the B-cell granule, proinsulin is converted into insulin and C-peptide of 31 amino acids [26] Previous studies completed on the unfolding process of insulin or proinsulin were often ... disulfide linkages of insulin have been shown to be important in maintaining its native conformation and biological activity [20–25] The double-chain insulin is synthesized in vivo as a single-chain...
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Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx
... protein is not assembled into the human complex I Inspection of the amino acid sequences of the known mammalian ESSS proteins reveals a high degree of conservation in the C-terminal domain (including ... protein–protein interactions with other hydrophilic domains of neighboring integral membrane subunits, and interspecies interactions are incompatible From the comparative studies with a series of Chinese ... to form a domain on the matrix side, and 36 form a domain extending into the intermembrane space In the third mutant (V79-G35) one might expect a protein to be inserted into the inner membrane,...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng 9 tr 25