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role of the european agency for the evaluation of medicinal products

Báo cáo y học:

Báo cáo y học: "The contemporary role of blood products and components used in trauma resuscitation" pdf

Báo cáo khoa học

... Surgery, Professor of Anesthesiology and Clinical Adjunct Professor of Emergency Medicine at the University of Minnesota Dr Dries also holds the John F Perry, Jr Chair of Trauma Surgery at the University ... licensed in the United States and other parts of the world for this purpose There is significant off-label use of rFVIIa in surgical applications including uncontrolled bleeding in the operating ... predictors of the need for massive transfusion [56] Massive transfusion was defined in this analysis as administration of at least 10 units of PRBCs during the initial phase of therapy The result...
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EudraLex The Rules Governing Medicinal Products in the European Union  Volume 4

EudraLex The Rules Governing Medicinal Products in the European Union Volume 4

Y học thưởng thức

... made of the time taken to complete the cycle, of the pressure, temperature and humidity within the chamber during the process and of the gas concentration and of the total amount of gas used The ... mechanisms 22 The transfer of materials into and out of the unit is one of the greatest potential sources of contamination In general the area inside the isolator is the local zone for high risk ... including the stages before sterilisation 65 Preparations of microbiological origin should not be made or filled in areas used for the processing of other medicinal products; however, vaccines of dead...
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Tài liệu

Tài liệu "Promoting healthy diets and physical activity: a European dimension for the prevention of overweight, obesity and chronic diseases" doc

Sức khỏe giới tính

... The objective of the Platform is to catalyse voluntary action across the EU by business, civil society and the public sector Members of the Platform include the key EU-level representatives of ... has been secured by Sports Ministers to offer support to the Platform A first evaluation of the outcomes of the Platform will take place mid-2006 20 IV.2 European Network on Nutrition and Physical ... maintain cardiovascular health, the recommended daily amount of exercise is at least 30 minutes for most of the days of the week There is no general agreement on the level of physical activity needed...
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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx

Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx

Sức khỏe giới tính

... equivocal The concern of the public health community about the resurgence and changing nature of TB in the United States prompted a re -evaluation of the role of BCG vaccination in the prevention ... RR-4 MMWR The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory ... Centers for Disease Control and Prevention The role of BCG vaccine in the prevention and control of tuberculosis in the United States: a joint statement by the Advisory Council for the Elimination of...
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Tài liệu The Role of Nutrition in Maintaining Health in the Nation’s Elderly: Evaluating Coverage of Nutrition Services for the Medicare Population ppt

Tài liệu The Role of Nutrition in Maintaining Health in the Nation’s Elderly: Evaluating Coverage of Nutrition Services for the Medicare Population ppt

Sức khỏe giới tính

... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the ... with the exception of the role of enteral and parenteral nutrition therapy, a preliminary review of the literature revealed insufficient data at this time regarding the role of nutrition therapy, ... care For this reason, the efficacy of the role of nutrition in diseases or conditions is independent of particular settings of care Each of the conditionspecific chapters addresses the strength of...
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Tài liệu Báo cáo Y học: Role of sulfoquinovosyl diacylglycerol for the maintenance of photosystem II in Chlamydomonas reinhardtii ppt

Tài liệu Báo cáo Y học: Role of sulfoquinovosyl diacylglycerol for the maintenance of photosystem II in Chlamydomonas reinhardtii ppt

Báo cáo khoa học

... pocket, which is the exit of the electron flow in the PSII complex According to the increase in the sensitivity to diuron in hf-2, the limitation of the electron transfer at the exit of the PSII complex ... conformational change of the PSII complex may cause the decrease of PSII activity in hf-2 by the lack of specific binding of SQDG to the PSII complex Alternatively, the change of the lipophilic surrounding ... condition The supplementation of SQDG in the medium enabled the mutant to grow even in the presence of diuron (Fig 3) The exogenously applied SQDG is incorporated into the mutant cells in the form of...
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Tài liệu Book of Abstracts of the 60th Annual Meeting of the European Association for Animal Production docx

Tài liệu Book of Abstracts of the 60th Annual Meeting of the European Association for Animal Production docx

Cao đẳng - Đại học

... Book of Abstracts of the 60th Annual Meeting of the European Association for Animal Production EAAP - European Federation of Animal Science The European Association for Animal Production ... Publishers The Netherlands, 2009 The designations employed and the presentation of material in this publication not imply the expression of any opinion whatsoever on the part of the European Association ... Development of a genetic indicator of biodiversity for farm animals 119 Software tools for management of genetic variation 120 Demonstration of the opportunities offered by a software for inbreeding...
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Role of The Controller - Mike Allred Associate Vice Chancellor for Finance & Controller UC-Davis doc

Role of The Controller - Mike Allred Associate Vice Chancellor for Finance & Controller UC-Davis doc

Kế toán - Kiểm toán

... for implementation of the initiative across the campus – Responsible for the quality of controls in areas directly reporting to them, and will assist other campus management in their responsibilities ... Communications to the Regents’ Committee on Audit • Letter of Comments & Recommendations to the Regents • Letter of Comments & Recommendations to the Chancellor – Reports to the Board of Regents from ... confidence in the financial markets in the wake of Enron, Tyco, Global Crossing, WorldCom, HealthSouth… – Created a new accounting oversight board to police the practices of the accounting profession...
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Báo cáo khoa học: Critical role of the plasma membrane for expression of mammalian mitochondrial side chain cleavage activity in yeast pptx

Báo cáo khoa học: Critical role of the plasma membrane for expression of mammalian mitochondrial side chain cleavage activity in yeast pptx

Báo cáo khoa học

... concentrations of the steroid (Fig 5) Therefore, these results reveal two levels of complexity of the CYP11A1 reaction in yeast On one hand, the content of free ergosta-5-eneol poorly correlates with the ... including the effect of the steroid products on the yeast sterol synthesis pathway, acetylation of the product, availability of the substrate, electron flow and localization of the different protein ... present, and the rate of progesterone biosynthesis is only marginally reduced compared to the rate observed for pregnenolone alone Therefore, an efficient coupling of the two first steps of steroidogenesis...
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Women raise their voices against tree plantations - The role of the European Union in disempowering women in the South docx

Women raise their voices against tree plantations - The role of the European Union in disempowering women in the South docx

Lâm nghiệp

... especially for the populations of the countries of the South In order for these raw materials and the products made from them to be produced and made available to the European public, a series of trade ... demands for the return of their land, compensation for the damages caused, restoration of the forests that have been destroyed, the suspension of further plantation activity, and the elimination of ... companies, the markets for their products are mainly European countries The Southern region of Brazil, called the “sul-rio-grandense Pampa” (grassland area of the state of Rio Grande Sul) extends for...
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EUROPEAN GUIDELINES FOR THE MANAGEMENT OF CHRONIC NON-SPECIFIC LOW BACK PAIN pot

EUROPEAN GUIDELINES FOR THE MANAGEMENT OF CHRONIC NON-SPECIFIC LOW BACK PAIN pot

Cao đẳng - Đại học

... recommend the wearing of a lumbar support for the treatment of nonspecific chronic low back pain C4 (D) Shortwave diathermy Summary of evidence • There is no evidence for the effectiveness of shortwave ... Summary of evidence • There is no evidence for the effectiveness of thermotherapy compared with sham/placebo treatments in the treatment of chronic low back pain (level D) • There is no evidence for ... developed for use in the objective evaluation of back muscle fatigue (De Luca 1993) Most commonly, the rate of decline of the mean or median frequency of the SEMG 44 power spectrum (and occasionally the...
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Center for Audit Quality Observations on the Evolving Role of the Auditor: A Summary of Stakeholder Discussions doc

Center for Audit Quality Observations on the Evolving Role of the Auditor: A Summary of Stakeholder Discussions doc

Kế toán - Kiểm toán

... appropriate, the CAQ formed a task force on the role of the auditor and moved to convene investors and other financial reporting stakeholders to examine the role of the auditor and the value of the audit ... isolation The “what, whys, and hows” related to changing the role of the auditor has to be considered within the context of the overall financial reporting system, including the important roles of the ... evolve the role of the auditor to meet the needs of investors in the near and longer term In the near term, the CAQ and its member firms have developed model reports for the PCAOB and other stakeholders...
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Báo cáo khoa học: New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases pot

Báo cáo khoa học: New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases pot

Báo cáo khoa học

... Together, these results confirm that the atom in the cluster is calcium To determine whether the calcium ion has a specific role in the activity of BsArb43B, assays were performed in the presence of ... in the absence of chelators (90.94 ± 7.85 UÆmg)1) These results suggest that the presence of calcium is important for the optimal activity of BsArb43B Furthermore, to determine whether the role ... that the presence of the C-terminal domain is crucial for the acquisition of the correct enzyme fold Analysis of the interactions between the two domains led us to presume that expression of the...
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Báo cáo khoa học: Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure pdf

Báo cáo khoa học: Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure pdf

Báo cáo khoa học

... 5B) Owing to the lower steric limitations of the side chain of the Ala than of the Leu, water may occupy the space Furthermore, the side chain of His140, which is coordinated to the T3 copper, ... similarities between the far-UV CD spectra of the mutants and that of the wild-type ScMaL not support any major conformational changes of the deletion mutant The reduced thermostability of the Sc(L559A) ... show the critical role of the last amino acids in the C-terminus of MaL Deletion of the four last amino acids strongly reduced the expression of the protein in T reesei and S cerevisiae Furthermore,...
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Báo cáo khoa học: Zinc-binding property of the major yolk protein in the sea urchin ) implications of its role as a zinc transporter for gametogenesis ppt

Báo cáo khoa học: Zinc-binding property of the major yolk protein in the sea urchin ) implications of its role as a zinc transporter for gametogenesis ppt

Báo cáo khoa học

... measured the protein content of the CFMYP and EGMYP bands by densitometry of the SDS ⁄ PAGE gel of the purified MYP, and the ratio of CFMYP to total MYP (CFMYP + EGMYP) was calculated (Fig 3B) In the ... testis at stage is still bound to MYP On the basis of the results of the present study and others, we propose a model for the synthesis and accumulation of MYP and its involvement in zinc transport ... expressed as the mean ± SEM Statistical analysis was performed using instat software (GraphPad Software) The normality of the distribution of data was evaluated using the Kolmogorov–Smirnov test The equality...
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Báo cáo khóa học: Assembly of the silk fibroin elementary unit in endoplasmic reticulum and a role of L-chain for protection of a1,2-mannose residues in N-linked oligosaccharide chains of fibrohexamerin/P25 ppt

Báo cáo khóa học: Assembly of the silk fibroin elementary unit in endoplasmic reticulum and a role of L-chain for protection of a1,2-mannose residues in N-linked oligosaccharide chains of fibrohexamerin/P25 ppt

Báo cáo khoa học

... secretion of H-chains There seem to be two key events in the assembly of the (H-L)6fhx1-type elementary unit: (a) the formation of disulfide-linked H-L heterodimers and (b) the formation of the three-component ... A role of L-chain in the protection of a1,2-mannose residues of the N-linked oligosaccharide chains of fhx/P25 in the elementary unit The PSG cell extract of Nd-sD mutant was subjected to the ... only the 27-kDa form is present in the Ó FEBS 2003 Role of L-chain in the elementary unit of fibroin (Eur J Biochem 271) 359 Fig Fractionation of ER from the PSG cell lysate and purification of the...
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Báo cáo khoa học:

Báo cáo khoa học: "QARLA:A Framework for the Evaluation of Text Summarization Systems" pdf

Báo cáo khoa học

... framework Even if the test is very limited by the number of topics, it confirms the potential of the framework, with the highest KING metric combination doubling the performance of the best ROUGE ... In the rightmost part of the figure, peers are distributed around the set of models, closely surrounding them, receiving a high JACK value A Case of Study In order to test the behaviour of our evaluation ... contrastive summary, the number of fragments of the reference summary which are also in the contrastive summary, in relation to the size of the contrastive summary DocSim: The number of documents used...
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Báo cáo khoa học:

Báo cáo khoa học: "A Figure of Merit for the Evaluation of Web-Corpus Randomness" ppt

Báo cáo khoa học

... g, for approximately half of the points (those laying in the B region), while the distance is between and h for the other half of the points (those in A) Therefore, if m is large enough, the ... ∪ B Approximately half of the points drawn from C will lie in the A square, while the other half will lie in the B square The distance of the points drawn from C from the points drawn from B ... between and h, the length of the diagonal of the rectangle which is the union of A and B Instead of drawing pairs we can draw triples of points, one point from A, one from B, and another point from...
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WORKING PAPER NO. 218 THE ZERO-INTEREST-RATE BOUND AND THE ROLE OF THE EXCHANGE RATE FOR MONETARY POLICY IN JAPAN potx

WORKING PAPER NO. 218 THE ZERO-INTEREST-RATE BOUND AND THE ROLE OF THE EXCHANGE RATE FOR MONETARY POLICY IN JAPAN potx

Ngân hàng - Tín dụng

... investigate the role of the exchange rate for monetary policy by exploring the performance of the three different proposals for avoiding or escaping the liquidity trap by means of depreciation of the ... downward bias in the variability of the real rate depending on the level of the nominal equilibrium rate of interest The downward bias in the variability of the real rate accounts for the reduced ... assume that the central bank adopts the proposal in the 11th period of the simulation Important choice variables are the initial price level of the implied target path, the extent of the devaluation...
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