role of oxidative stress in female reproduction reproductive biology and endocrinology
The effects of oxidative stress on female reproduction: a review ppt
Ngày tải lên :
05/03/2014, 16:20
... independ-
ent of body mass index (BMI), is responsible for an in-
crease in oxLDL [71]. Insulin resistance and/ or
compensatory hyperinsulinemia increase the availability
of both circulating androgen and androgen ... system also plays a role in female reproduction
and fetal development by being involved in cell growth,
differentiation, and death. Incorrect protein folding and
formation of disulfide bonds can ... JG: Role of oxidative stress in
endometriosis. Reprod Biomed Online 2006, 13:126–134.
22. Agarwal A, Gupta S, Sharma RK: Role of oxidative stress in female
reproduction. Reprod Biol Endocrinol...
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The role of sentence stress in enhancing english speaking competence of HPU english majors
Ngày tải lên :
17/03/2014, 16:12
... majors in enhancing
English speaking competence. 49
2.1. Misunderstanding of meaning caused by wrong placement of stress 49
2.2. Misunderstanding of meaning caused by changes in sentence stress. ... distinguish between four levels of stress: major
sentence stress, major word stress, minor word stress and unstressed.
Thus, in the sentence: “I walked home in the rainstorm”.
‗I‘, in , and ... meaning and none of them
denied the role of producing accurate sentence stress. However, a problem,
their strong attitude, cognition and utilization sentence stress in enhancing
speaking competence...
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báo cáo hóa học: " The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer''''s disease" ppt
Ngày tải lên :
19/06/2014, 22:20
... complex leads to the
initiation of complex signaling events leading to protein
tyrosine phosphorylation and activation of the src-family
kinases Lyn and Fyn as well as the tyrosine kinase Syk
[30,32,52]. ... [86,91-94]. Levels of both dityrosine and
nitrotyrosine are elevated in brain regions specifically
affected in AD [91]. Protein nitration is also increased in
the hippocampus of AD patients compared ... the inducible nitric oxide synthase
(iNOS) [75-77]. Fibrillar Aβ peptides stimulate the induc-
tion of iNOS and NO production through an NADPH-
dependent oxidative deamination of L-arginine
[56,75,78,79]....
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Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
Ngày tải lên :
19/02/2014, 17:20
... not the terminal
trimming of N-glycans is involved in the regulation of
the stability and trafficking of GAT1. It has been
reported that a variety of molecular chaperones and
folding enzymes assist ... substrate
binding process. This provides strong evidence that
N-glycans, in particular their terminal structures, are
involved in regulating the GABA translocation of
GAT1, but not in binding of GAT1 ... ⁄ P
i
and blocked with 5%
bovine serum albumin and 0.1 m glycine in NaCl ⁄ P
i
for
30 min and washed with NaCl ⁄ P
i
again. Polyclonal antibod-
ies against GAT1 were used for immunostaining at...
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Tài liệu Báo cáo khoa học: Enhancement of oxidative stress-induced apoptosis by Hsp105a in mouse embryonal F9 cells pptx
Ngày tải lên :
21/02/2014, 03:20
... determine the
effects of Hsp105a on JNK and p38 signalling pathways, we
examined the activation of JNK and p38 in F9 cells by
oxidative stress. As shown in Fig. 6A, JNK was not
activated in control ... activation of p38 induced by
oxidative stress, we further examined whether its activation
is responsible for the induction of apoptosis in F9 cells using
SB202190, a potent inhibitor of p38. As shown in ... peroxide. In contrast, hydrogen peroxide-treat-
ment induced marked activation of JNK within 30 min in
S23 cells, but not in S3 cells. Therefore, the enhancement of
the oxidative stress- induced...
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Báo cáo khoa học: Calcium, mitochondria and oxidative stress in neuronal pathology Novel aspects of an enduring theme pdf
Ngày tải lên :
07/03/2014, 12:20
... imposing a continuous load of
calcium to the neuron. The turning point upon which
the cell looses the ability to buffer the incoming calcium
resulting in an abrupt, sustained and irreversible
increase ... by proteins resi-
ding in both the inner and outer mitochondrial
membrane, that is activated by mitochondrial Ca
2+
overloading and other factors including oxidative stress
[88,89]. In neurons ... for a role of Trp proteins in the oxidative
stress- induced membrane conductances of porcine
aortic endothelial cells. Cardiovasc Res 42, 543–
549.
236 Wehage E, Eisfeld J, Heiner I, Jungling E,...
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Báo cáo khoa học: Effect of oxidative stress and involvement of poly(ADP-ribose) polymerase (PARP) in Dictyostelium discoideum development doc
Ngày tải lên :
23/03/2014, 07:20
... PARP inhibitor, on oxidative stress- induced changes in
D. discoideum development. Interestingly, oxidative stress resulted in PARP
activation within 5 min that was inhibited by benzamide. Oxidative ... development.
HA-induced oxidative stress activates PARP within
5 min (Fig. 4A,B), and its role during oxidative stress
is further confirmed by the use of low concentrations
of benzamide. Preincubation of cells ... the response of this organism to oxidative stress
and the role of PARP during development. We used hydroxylamine (HA)
to induce in situ generation of H
2
O
2
and monitored the effect of
benzamide,...
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Báo cáo hóa học: " Oxidative stress in NSC-741909-induced apoptosis of cancer cells" potx
Ngày tải lên :
18/06/2014, 16:20
... cell
activity of several LOX inhibitors, including aesculetin (a
nonselective LOX inhibitor), MK886 (an inhibitor of the
5-LOX-activating protein), zileuton (a 5-LOX inhibitor),
baicalein (a 12/15-LOX inhibitor), ... [11,12], and pro-
mote apoptosis. In fact, ROS-induced oxidative stress
and cell death play important roles in the efficacy of many
antineoplastic agents [13,14].
To investigate whether oxidative stress ... leads to inactivation of
MKPs and activation of MAPKs [7-9]. ROS-mediated
inhibition of MKPs is critical for TNFα-induced sus-
tained activation of JNK and subsequent apoptosis [7].
Interestingly,...
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báo cáo hóa học: " Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis" pptx
Ngày tải lên :
19/06/2014, 22:20
... implicating both oxidative
stress and inflammatory mechanisms in AD pathogenesis.
Effect of indomethacin plus vitamin E supplementation on sol-uble Aβ levelsFigure 3
Effect of indomethacin plus ... a subset of NSAIDs
(e.g. ibuprofen, flurbiprofen, indomethacin) reduced
brain inflammation and Aβ levels in addition to the dep-
osition of Aβ in brain [13,14]. Despite this evidence, and
the ... that a full dose of
indomethacin alone despite a significant reduction in
brain inflammation had only a marginal effect on brain
oxidative stress in the Tg2576 mice [16]. This finding sug-
gests...
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báo cáo hóa học: " Biomarkers of oxidative stress and its association with the urinary reducing capacity in bus maintenance workers" pptx
Ngày tải lên :
20/06/2014, 00:20
... response of the organism to particle-induced oxida-
tive stress. The observed increase of reducing species in
urine would mirror an increased level in blood originat-
ing from a response to oxidative ... within-shift variation of 8OHdG (% of initial value) and
within-shift reduced species (% of initial value) for smokers and non smokers.
Sauvain et al. Journal of Occupational Medicine and Toxicology ... 8OHdG and reducing species. (a) Correlation between urinary levels of 8OHdG ( in μg/g creatinine) and
reduced species (in μW/g creatinine) for all collected samples. (b) Correlation between within-shift...
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Báo cáo khoa học: "Comparative study of PM2.5 - and PM10 - induced oxidative stress in rat lung epithelial cells" pptx
Ngày tải lên :
07/08/2014, 17:22
... C, Becker S.
Cytotoxicity and induction of
proinflammatory cytokines from human monocytes exposed
to fine(PM
2.5
) and coarse particles(PM
10
-
2.5
) in outdoor and
indoor air. Toxicol Appl Pharmacol ... PM10
suggesting that PM2.5 induced more oxidative stress than
PM10. In the single strand breakage assay using pBR322
DNA, the ratio of changed form II/total plasmid DNA (form
F
ig. 10. RT-PCR analysis of ... 11–18
Comparative study of PM2.5 - and PM10 - induced oxidative stress
in rat lung epithelial cells
Jin-Hyuk Choi, Jun-Sung Kim, Young-Chul Kim
1
, Yoon-Shin Kim
2
, Nam-Hyun Chung
3
and
Myung-Haing Cho*
Laboratory...
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Báo cáo khoa học: " Induction of oxidative stress and lipid peroxidation in rats chronically exposed to cypermethrin through dermal application" pps
Ngày tải lên :
07/08/2014, 23:22
... decreases in
GSH levels in our study may be due to either the inhibition
of GSH synthesis or increased utilization of GSH for
detoxification of toxicant induced free radicals [33]. The
decrease in ... reported in
Nilaparvata lugens, a pyrethroid insecticide resistant
strain of insect [38]. GST levels were also increased
significantly after 30 days of exposure to protect RBCs
from oxidative ...
significantly reduced (p ＜ 0.05) in all groups compared to
the control group. Similar finding have been reported in
other study during oxidative stress [24]. No significant
changes in GST activity was...
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