role of oxidative stress and inflammation
Báo cáo khoa học: Effect of oxidative stress and involvement of poly(ADP-ribose) polymerase (PARP) in Dictyostelium discoideum development doc
Ngày tải lên :
23/03/2014, 07:20
... to oxidative stress
and the role of PARP during development. We used hydroxylamine (HA)
to induce in situ generation of H
2
O
2
and monitored the effect of
benzamide, a PARP inhibitor, on oxidative ... development and also the role of PARP
in oxidative stress- induced effects on development.
Our present study is the first report on the activation
of PARP under oxidative stress in D. discoideum, and
our ... 4A,B), and its role during oxidative stress
is further confirmed by the use of low concentrations
of benzamide. Preincubation of cells with benzamide
prevented the peak activity observed during oxidative
stress...
- 8
- 363
- 0
Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
Ngày tải lên :
06/03/2014, 19:20
... insights into the roles and mechan-
isms of PM
2.5
-associated physiology and pathology.
In summary, our data demonstrate the important
effects of PM
2.5
exposure on oxidative stress and mito-
chondrial ... shows
representative TEM images of mitochondria in eWAT
(Figures 2A and 2B) and iBAT (Figures 2C and 2D),
respectively, and the analyses of mitochondria number
(Figure 2E) and area (Figure 2F). In the ... insulin
resistan ce, oxidative stress, alteration of vasomotor tone,
vascular and visceral inflammation, adiposity, and
atherosclerosis in apolipoprotein E knockout (ApoE
-/-
)
mice and other several...
- 14
- 466
- 0
Báo cáo khoa học: Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice pdf
Ngày tải lên :
22/03/2014, 16:20
... overexpression of CYP2E1 both in vivo
and in vitro is associated with several cellular markers
of oxidative stress, including products of lipid peroxi-
dation (e.g. 4-hydroxynonenal and malondialdehyde),
as ... of CYP2E1 in mouse heart tissue and the generation of transgenic mice. Protein translational levels of CYP2E1 in heart
tissue from mice at embryonic age 16.5 days and at 1, 2, 4 and 8 weeks of ... toxicity in rat hepatocytes, role
of CYP2E1 and mitochondria. Hepatology 35, 1420–
1430.
28 Cederbaum AI (2006) Cytochrome P450 2E1-dependent
oxidant stress and upregulation of anti-oxidant defense
in...
- 9
- 404
- 0
Báo cáo khoa học: The silencing of adenine nucleotide translocase isoform 1 induces oxidative stress and programmed cell death in ADF human glioblastoma cells doc
Ngày tải lên :
29/03/2014, 09:20
... Analysis of ANT1 and ANT2 expres-
sion in nontransfected ADF cells and in
ANT1- and ANT2-silenced ADF cells. (A)
Number of ANT1 and ANT2 transcripts in
nontransfected ADF cells. (B) Number of
ANT1 ... pro-
tein level. Because of the absence of a specific antibody
able to discriminate between isoforms 1 and 2, only a
partial reduction of ANT protein is appreciable after
ANT2 and especially ANT1 siRNA ... provide new information
about the function of ANT proteins in the regulation
of cell death⁄ survival processes. We analyzed the role
of ANT1 and ANT2 isoforms in a human glioblas-
toma cell line,...
- 15
- 378
- 0
Tài liệu OXIDATIVE STRESS AND DISEASES pptx
Ngày tải lên :
12/02/2014, 16:20
... production and removal
of homocysteine and cysteine, Annual Review of Nutrition, Vol. 24, pp. 539-577.
Sultana, R., & Butterfield, D.A. (2010). Role of oxidative stress in the progression of
Alzheimer’s ... in structural genes of complex I associated with
Oxidative Stress: Cause and Consequence of Diseases
15
enzymes of these two big groups may lead to oxidative stress and consequent diseases, ... knowledge on the role of
oxidative stress in origin of diseases as well as its significance in disease complications. It
was it that oxidative stress is described over developed pathology and nothing...
- 624
- 1.9K
- 0
Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx
Ngày tải lên :
18/02/2014, 11:20
... selection of recombinants. The sites
incorporated were HaeIII, NcoI and BamHI (Table 1). The
PCR mix contained 200 ng of each primer, 20 ng of the tem-
plate, 200 lm of each dNTP and 5 units of Taq ... Department of Biotechnology
(DBT), Department of science and technology (DST),
Council of Scientific and Industrial research (CSIR)
and senior research fellowship from CSIR, Govern-
ment of India.
References
1 ... between AÂ and AÂÂ [the
guanidine group and aromatic residues of
PfTIM (R98 F102)] and the BÂ guanidine and
sulfur groups of GlTIM (R99 ⁄ M103) are
marked.
M. Banerjee et al. Effect of mutation...
- 15
- 635
- 0
Tài liệu Báo cáo khoa học: Role of hydroxyl group and R/S configuration of isostere in binding properties of HIV-1 protease inhibitors docx
Ngày tải lên :
19/02/2014, 16:20
... Sedla
´
c
ˇ
ek
3
and Jindr
ˇ
ich Has
ˇ
ek
1
1
Institute of Macromolecular Chemistry,
2
Institute of Organic Chemistry and Biochemistry and
3
Institute of Molecular Genetics,
Academy of Sciences of the ... C
c
atoms of Phe53 and Phe153). In the case of Ôwide tunnelÕ, the diameter of t he effective view through the
solvent channel is 12.4 A
˚
(measured a s a distance of projections of opposite S
d
atoms of ... C
a
of OE is
shifted h igher t o t he fl aps than C
a
of SE and RE inhibitors
(about 0.5 A
˚
in both cases). Although phenyl rings of OE
and RE have very similar positions and orientation and
have...
- 11
- 615
- 0
Tài liệu Báo cáo khoa học: Enhancement of oxidative stress-induced apoptosis by Hsp105a in mouse embryonal F9 cells pptx
Ngày tải lên :
21/02/2014, 03:20
... growth rate and differentiation
of F9 cells were not affected by the over-expression of
Hsp105a, the sensitivity of cells to oxidative stress was
enhanced by the over-expression of Hsp105a,andthese
findings ... activation of p38
is an essential step for induction of apoptosis by hydrogen
peroxide, and Hsp105a is suggested to enhance the oxida-
Fig. 6. Effects of Hsp105a on activation of
JNK and p38 by oxidative ... cleavage, caspase-3
activation and release of cytochrome c from mitochondria
in F9 cells exposed to hydrogen peroxide, and our results
Fig. 7. Suppression of oxidative stress- induced
apoptosis in...
- 9
- 366
- 0
The effects of oxidative stress on female reproduction: a review ppt
Ngày tải lên :
05/03/2014, 16:20
... Nephrotoxins: widespread role of
oxidative stress and electron transfer. Curr Med Chem 2002, 9:823–847.
324. Kovacic P, Jacintho JD: Mechanisms of carcinogenesis: focus on oxidative
stress and electron transfer. ... Role of oxidative metabolites of cocaine in toxicity and
addiction: oxidative stress and electron transfer. Med Hypotheses 2005,
64:350–356.
333. Goldstein S, Samuni A, Merenyi G: Reactions of ... study: effects of
fruit and vegetables on markers of oxidative stress and antioxidative
defense in healthy nonsmokers. Am J Clin Nutr 2004, 79:1060–1072.
122. Huang HY, Appel LJ, Croft KD, Miller...
- 31
- 1.7K
- 0
Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx
Ngày tải lên :
07/03/2014, 16:20
... ê 2004 FEBS
The role of helix 8 and of the cytosolic C-termini in
the internalization and signal transduction of B
1
and B
2
bradykinin receptors
Alexander Faussner
1
, Alexandra Bauer
1
, Irina ... that of B
1
CB
2
and
B
1
YB
2
(Fig. 2B).
Phosphorylation patterns of B
2
wt and of B
1
⁄ B
2
chimeras reflect their agonist-inducible
internalization
Agonist-induced phosphorylation of serine and ... kinases.
Results
Construction of truncated and point mutated
B
2
wts and B
1
⁄ B
2
receptor chimeras
Several studies with truncations of, and deletions in,
the C-terminal part of B
2
wt have demonstrated...
- 12
- 595
- 0
Role of an electrolyte and substrate on the stability of porous silicon
Ngày tải lên :
16/03/2014, 15:19
... degradation of stability of PS on
electrolyte (HF–C
2
H
5
OH and HF–H
2
O
2
) and
current density formed on textured and polished
Si substrates, respectively. The emphasis is mainly
on the development of ... to
partial merging of nanopores and the formation of
a high porosity region which can deform and
release the stress at dimensions small enough to
prevent macroscopic crack formation and fragility.
Thus ... former
(Figs. 5(C) and (D)). The higher current density
results in increased porosity and the inability of
the silicon nanowires to withstand the stress leads
to cracking.
The surface morphology of PS films...
- 9
- 537
- 0
Tìm thêm:
- hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam
- xác định các mục tiêu của chương trình
- xác định các nguyên tắc biên soạn
- khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn
- khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản
- khảo sát chương trình đào tạo gắn với các giáo trình cụ thể
- xác định thời lượng học về mặt lí thuyết và thực tế
- tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam
- điều tra đối với đối tượng giảng viên và đối tượng quản lí
- điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1
- khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam
- khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu
- nội dung cụ thể cho từng kĩ năng ở từng cấp độ
- xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct
- phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ
- mở máy động cơ lồng sóc
- mở máy động cơ rôto dây quấn
- các đặc tính của động cơ điện không đồng bộ
- hệ số công suất cosp fi p2
- đặc tuyến hiệu suất h fi p2