role of drugs and drug products in the treatment and prevention of disease
Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis docx
Ngày tải lên :
06/03/2014, 04:20
... the key role of the rifamycins in the success of tuberculosis treatment mandates that the drug- drug interactions between the rifamycins and antiretroviral drugs be managed, not avoided by using ... 8, Predicting Drug Interactions Involving Rifamycins Knowledge of the mechanisms of drug interactions can help predict the likelihood of an interaction, if that specific combination of drugs has ... evaluated The rifamycin class upregulate (induce) the synthesis of several classes of drug transporting and drug metabolizing enzymes With increased synthesis, there is increased total activity of the...
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Effects of anti malaria drug artesunate in the treatment of rhinovirus induced asthma exacerbation
Ngày tải lên :
09/09/2015, 11:16
... with the residues in other site of the surface These conserved sites have been shown to be the binding sites of the receptors and thus block the binding of the neutralizing binding sites of antibodies ... Blockage of the binding site with several compounds could also stabilize the viron and actually many drugs act at the entry level by binding to these sites and thus inhibit the binding of the virus ... current drugs are only able to control the symptoms None of them are able to eliminate the disease The major unmet in this area include better management of the severe forms of the disease and development...
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Tài liệu CONSUMER PREFERENCE AND CONSUMPTION OF ORGANIC PRODUCTS IN THE EASTERN CAPE PROVINCE OF SOUTH AFRICA docx
Ngày tải lên :
14/02/2014, 03:20
... are marked increases in the future demand of all organic products This augurs well for the growth of the organic industry in the Eastern Cape and in South Africa in general The findings of this ... maintain its identity in the face of others, and therefore creates a feeling of "belonging" (Buruiana 2003) 17 10 Factors affecting the consumer awareness of organic products The results of the ... consumers in the ranking of price, quality, health and nutrition values, packaging/size and availability of organic products as key motivating factors in the purchase of organic products Interestingly,...
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Báo cáo lâm nghiệp: "Evaluation of squared timber and log products in the Hyrcanian Forests of Iran" doc
Ngày tải lên :
07/08/2014, 10:21
... 421,905 (22%) These forests form rather a narrow green belt bordering the northern part of the Alborz Mountains and extend from Astara in the west of Gilan Province to Giledarreh in the east of Golestan ... between them in the Hyrcanian Forests of Iran during the last 20 years MATERIALS AND METHODS Areas under Study Located in the northern part of Iran, the study areas are known as the Northern Forests ... 65 the Huber formula and measuring the lengths and middle diameters of logs and the logs were extracted by skidders (Fig 3) Furthermore, the processes of forest harvesting systems progress in the...
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báo cáo khoa học: " ’It’s risky to walk in the city with syringes’: understanding access to HIV/AIDS services for injecting drug users in the former Soviet Union countries of Ukraine and Kyrgyzstan" ppt
Ngày tải lên :
11/08/2014, 14:21
... services including HIV prevention and treatment and drugs treatment We identify and explore eight key sets of factors constraining access to Global Fund-financed HIV/ AIDS services based on the accounts ... accounts of HIV/AIDS service clients, frontline providers and stakeholders in the field of HIV/AIDS: • stigmatisation of HIV/AIDS and drugs use; • criminalisation of drugs use; • discriminatory ... control activities financed by the Global Fund and other donors in Ukraine and Kyrgyzstan aimed to address the problems stemming from the criminalisation of drugs use both at national and local levels...
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báo cáo khoa học: " Seroprevalence of select bloodborne pathogens and associated risk behaviors among injection drug users in the Paso del Norte region of the United States – Mexico border" ppt
Ngày tải lên :
11/08/2014, 18:20
... 3) Heroin alone was the drug injected most often in the past six months in New Mexico (69.0%) and Texas (66.5%), whereas in Mexico the 'speedball' or combination of heroin and cocaine was the most ... aware of any needle exchange programs in your area? No Yes No answer Which of the following drugs you inject most often in the past months? Heroin Cocaine Speedball (heroin + cocaine) Other No ... reported at the other two sites Overall, there were high rates of injection drug use seen in families, including inter-generational findings The Mexico site reported larger social network sizes and more...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
Ngày tải lên :
25/10/2012, 10:51
... 2004, of portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free -drug levels; increase in volume of distribution ... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of ... low levels of serum albumin and higher levels of unexcreted metabolites competing for protein binding sites, resulting in increased bioavailability of free, active highly protein-bound drugs Accumulation...
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Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
Ngày tải lên :
26/10/2012, 09:48
... provide written informed consent Use of other natural health products, including glucosamine and chondroitin, one month prior to study and during the study, other than multivitamin and mineral supplements ... capsule contains 375 mg of glucosamine HCl (USP Grade) and 300 mg of chondroitin sulfate (USP Grade) The subjects were instructed to take two G+C capsules in the morning and two in the evening for ... therapy, joint protection and physiotherapy/occupational therapy agrees to continue these therapies as normal avoiding changes in frequency or intensity and to record therapies in the study diary...
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Tài liệu New and improved Products in the FIBRO Standard Parts Catalogue 2008 docx
Ngày tải lên :
26/01/2014, 20:20
... feeders, press linking, palletising, stacking, loading and unloading, transporting and flexible linking, storage and buffering of work pieces of different sizes Since its establishment in 1974 GSA ... 19 Casting/tooling resins: thinning agent H9 Centering pin for lifting flange C 15/4 Centring inserts D 213 Centring pins to Daimler standard D 215 Centring pins to VW standard D 214 Centring units ... successfully in many industries worldwide Applications include linking machine tools (automotive production), tool changing in machining facilities, palletising work pieces, unloading injection moulding...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
Ngày tải lên :
14/02/2014, 22:20
... tissue and gastrointestinal tract, as well as other sites, are known to reach the CNS to effect changes in feeding behavior and energy expenditure Thus, insulin, leptin and ghrelin, as well as other ... closely and rapidly with reciprocal changes in the levels of the orexigenic and anorectic Signaling mediators in the treatment of obesity neuropeptide expression in the hypothalamus [22] Thus an increase ... expressed in neurons so CPT1c and CPT1a largely not localize to the same cells in the brain, suggesting that they are functionally distinct Although Signaling mediators in the treatment of obesity...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
Ngày tải lên :
06/03/2014, 01:20
... at each phase of the cell cycle by various complexes of cell-cycle-related molecules, including cyclins, cyclin-dependent kinases, their inhibitors and the retinoblastoma protein (RB), as well ... calorie intake induces expression of RMI1 and E2Fs in adipocytes, and these changes in expression are expected to increase a positive interaction between the molecules The increased expression of ... recruitment of preadipocytes [12], suggesting that these cyclin-dependent kinase inhibitors are important in the regulation of adipocyte number The S-phase kinase-associated protein (Skp)1–CullinF-box...
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Role of Corticosteroids in the Treatment of Tuberculosis: An Evidence-based Update potx
Ngày tải lên :
06/03/2014, 04:20
... opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America ... imaging of the brain was also performed in a subset of patients in this study.36 It was found that use of corticosteroids possibly reduced the risk of developing hydrocephalus and vasculitic infarcts; ... M, Hemingway C, Scott G, Solomon T, Innes J British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children J Infect...
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báo cáo hóa học:" Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement" doc
Ngày tải lên :
20/06/2014, 04:20
... screening including erythrocyte sedimenta- Page of tion rate and C-reactive protein was normal Plain radiographs revealed areas of periprosthetic osteolysis in the femur and the tibia, and a ... image of the left knee showing the introducing cannula and simultaneous venting of the medial tibial condylar cyst Discussion When dealing with massive periprosthetic osteolysis the aims of surgery ... years later In January 2005 the patient began to develop similar medial pain and swelling in the left knee A bone scan showed increased activity in the medial femoral condyle indicating possible...
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Báo cáo y học: "Role of Leukotriene Receptor Antagonists in the Treatment of Exercise-Induced Bronchoconstriction: A Review" pot
Ngày tải lên :
08/08/2014, 20:23
... action of a single mediator (An in- depth discussion of the mediators involved in EIB and their cellular sources are beyond the scope of this review.) 61 activity in individuals with underlying airway ... for the treatment of EIB.12 Results are varied; routine use of these types of pharmacologic intervention is not recommended as primary treatment of EIB.12 Other therapies are still being investigated.12 ... ventilation (exercise intensity), temperature and humidity of the inspired air (climatic conditions), and underlying baseline airway responsiveness are the primary determinants of the degree of EIB a patient...
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Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf
Ngày tải lên :
08/08/2014, 23:21
... Annals of General Psychiatry 2009, 8:16 the treatment of acute mania, the approval of quetiapine and the olanzapine-fluoxetine combination against acute bipolar depression and the approval of olanzapine, ... dose at the end of the study was 15.5 mg daily The results suggest that in weeks to and then again at week there is a significant reduction in the MADRS scores in the aripiprazole group in comparison ... which included 66 of the 67 patients who completed the 26-week period Unfortunately only 12 of them (5 in the placebo group and in the aripiprazole group) completed the 74-week treatment period The...
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Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx
Ngày tải lên :
08/08/2014, 23:21
... effective in the treatment of psychotic major depression, and the switch to sertraline worsened the psychotic symptoms in the patient The mechanisms underlying the opposite effects of these two ... fluvoxamine binds to sigma-1 receptors in the intact human brain at therapeutic doses [25], suggesting that sigma-1 receptors are involved in the active mechanisms of fluvoxamine [19] Interestingly, ... that activation of the dopaminergic system by the inhibition of dopamine transporter may be involved in the mechanism of unwanted effects (deterioration of psychosis) of sertarline in this case,...
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Báo cáo y học: "The role played by cell-substrate interactions in the pathogenesis of osteoclast-mediated peri-implant osteolysis" potx
Ngày tải lên :
09/08/2014, 07:20
... neither the β3 integrin nor the CTR are expressed by osteoclast precursors The expression of these genes increases during the late stages of osteoclast differentiation [42], after induction of the ... implicating osteoclasts in the pathogenesis of the peri-implant osteolysis associated with prosthetic implant wear debris The findings of TRAP and cathepsin K expression in macrophages and foreign ... induction of the cathepsin K and TRAP genes Importantly, the transcriptional activation of the β3 integrin and CTR genes coincides with the transition of the osteoclast to an actively resorbing cell [10]...
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Báo cáo khoa học: "Factors of influence upon overall survival in the treatment of intracranial MPNSTs. Review of the literature and report of a case" doc
Ngày tải lên :
09/08/2014, 09:20
... contributions All of the authors have been involved in drafting this paper and have read and approved the final manuscript KG conceived the idea of the paper, reported the case, performed the literature ... concerning radiotherapy and followed up the patient at his out-patient clinic AK was the radiologist performing the preoperative and postoperative CT and MRI scans and wrote the part of the paper ... radiation in their history Other studies haven’t shown any positive effects of radiotherapy on patients outcome[30-32], while the recent literature indicates the beneficial role of the radiotherapy in...
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Báo cáo khoa học: "Helical tomotherapy in the treatment of pediatric malignancies: a preliminary report of feasibility and acute toxicitty" doc
Ngày tải lên :
09/08/2014, 09:21
... HT at the Tomotherapy Unit of the Grupo IMO in the context of multidisciplinary national and international treatment protocols All the patients were treated with curative intent, including those ... to the Tomotherapy treatment planning system (Tomotherapy Inc., Madison, WI) to perform inverse treatment planning The planning goal was to deliver the prescription dose to at least 95% of the ... treatment time was composed of time required for patient set-up and anesthesia inside the treatment room, time of MVCT acquisition, time of review/match and applying couch correction inside the...
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Báo cáo khoa học: " Intensity modulated radiotherapy (IMRT) in the treatment of children and Adolescents - a single institution''''s experience and a review of the literature" pps
Ngày tải lên :
09/08/2014, 10:20
... treatment of the children HB is responsible for the anaesthesia management of the children PH is responsible for the clinical treatment of the children as head of the division of radiation oncology in ... helical tomotherapy have the potential of selectively sparing the thyroid gland and breast tissue in craniospinal irradiation The number of children treated with IMRT and the hard evidence for the benefit ... percent of the IMRT Group had grade or hearing loss, compared to 64% of the conventional-RT group The sparing of the hearing apparatus is of special importance since several modern combined chemotherapy...
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