role of capital market authority in the economy
The Role of Digital Identity Management in the Internet Economy doc
Ngày tải lên :
23/03/2014, 23:21
... managing and protecting digital identities, with
a view to strengthening confidence in the online activities crucial to the growth of the Internet Economy.
The primer is a product of the Working ... protection of individuals and their digital identities.
As a key factor in increasing trust in online activities, IdM is also a key factor in fostering the growth
of the Internet economy. Given the ... maintained in multiple accounts within the organisation. The organisation is in some sense
wasting resources and duplicating efforts in maintaining separate profiles with (mostly) the same
information....
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Tài liệu Role of diffusion-weighted imaging in the diagnosis of gynecological diseases pdf
Ngày tải lên :
13/02/2014, 06:20
... a
well-defined hyperintensity mass in the cervical area. The shape of
the uterine cervix is distorted in the DWI (arrowhead). d On the
ADC map the tumor is hypointense (arrow) and the normal ... imaging technique (SENSE factor
of 2). Imaging time of DWI was 90 s for 20 slices.
Detection of uterine malignancy
The ADC values of uterine cancers are lower than of
normal tissue. On the other ... with uterine leiomyomas and a
bleeding cyst. a Axial T2-WI shows an area of hypointensity in the
center of the cystic component (arrow). b On T1-WI with fat
suppression the area in the cystic...
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Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
Ngày tải lên :
18/02/2014, 16:20
... of PKA in the mitochondrial targeting of
CYP2E1
The role of PKA in mitochondrial targeting of
CYP2E1 was investigated using two approaches. The
first approach involved measuring the level of mito-
chondrial ... microsomes requires the co-
translational insertion of the newly synthesized protein
into the microsomal membrane, where the N-terminal
hydrophobic signal sequence of the protein interacts
with a ... mitochondria-targeting signal
in the yeast system.
Mitochondrial localization of intact CYP2E1
in yeast cells
Because of the existing ambiguity in the literature on
the nature and extent of CYP2E1 import into...
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Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
Ngày tải lên :
19/02/2014, 13:20
... provided
further insight into the molecular mechanism driving the
formation of the covalent C115–fosfomycin adduct. A
conservative exchange of K22 to arginine maintains fosfo-
mycin binding, while ... form of the protein.
The results obtained with the K22V/R120K double
mutant protein point toward a central role of arginine 120
in the conformational process occurring during catalysis.
Therefore, ... a
rationale for these findings: the side chain amino group of
K22 engages in a salt-bridge interaction with the phospho-
nate group of fosfomycin (Fig. 5). Clearly, the guanidinium
group of arginine can,...
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Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf
Ngày tải lên :
21/02/2014, 03:20
... dependence of the pH-activity curve of API
The pH-activity profiles depending on NaCl concentration
were determined as part of the investigation into the
shielding from solvent of the electrostatic interaction
between ... position. In the struc-
tural deviation, the solvent ASA of the side-chain of His210
increased with the decrease in size of the side-chain at
residue 169 (Table 1 and Fig. 3A). However, the ASAs of
Asp113 ... size of the side-chain at residue 169 and the pK
2
showed a clear linear relationship (Fig. 3B). The pK
2
increased as the size of the residue at position 169 increased.
The effect of the size of...
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Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt
Ngày tải lên :
07/03/2014, 04:20
... by
the C domain of the initiation module of dapto-
mycin. That DptE and DptF are involved in the
lipidation process of daptomycin was first shown by
Miao et al. [1]. In their work, the daptomycin ... is GLDSV,
indicating that this putative ACP domain is one of the
few ACPs in which valine replaces isoleucine (I) or
leucine (L) in the conserved sequence. To determine
whether DptF is the putative ... [37].
Interestingly, in the case of the lipopeptide surfactin,
neither an acyl CoASH ligase-like domain nor an ACP
could be identified within the biosynthetic gene cluster
using bioinformatic tools...
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Báo cáo khoa học: "Examining the Role of Linguistic Knowledge Sources in the Automatic Identification and Classification of Reviews" doc
Ngày tải lên :
17/03/2014, 04:20
... documents and find that the fea-
ture vectors corresponding to some of these docu-
ments (particularly the short ones) have all zeroes
in them. In other words, none of the bigrams from
the training set ... cap-
turing two different situations, one in which the
author himself likes the movie, and in the other,
the author’s cousin likes the movie. The over-
generalization resulting from these “stemmed” ... available.
612
Proceedings of the COLING/ACL 2006 Main Conference Poster Sessions, pages 611–618,
Sydney, July 2006.
c
2006 Association for Computational Linguistics
Examining the Role of Linguistic Knowledge...
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Báo cáo khoa học: Role of calcium phosphate nanoclusters in the control of calcification pot
Ngày tải lên :
29/03/2014, 23:20
... used to describe the binding
isotherms obtained previously for the b-casein 1–25 phos-
phopeptide in this pH range, and the same model was
adapted to fit the binding isotherm of OPN 1–149 mea-
sured ... mixture of scattering from copolymer micelle-like nanoclus-
ters and free peptide. The scattering of the nanoclusters was obtained by subtracting the scattering of the free peptide from the total ... solutions
containing high concentrations of Ca, P
i
and the phospho-
peptide, the concentration gradients generated and their
persistence during inefficient mixing can allow the inital
ACP to mature into...
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Báo cáo khoa học: Membrane compartments and purinergic signalling: the role of plasma membrane microdomains in the modulation of P2XR-mediated signalling pot
Ngày tải lên :
30/03/2014, 02:20
... dur-
ing lipid raft isolation. Moreover, these studies have
provided some insights into the significance of the
localization of the P2X
7
receptors in lipid rafts regard-
ing the regulation of intracellular ... (glycero-)sphingolipids. In addition the
fatty acid chains of the phospholipids composing
these rigid domains are generally more saturated than
those in the lipids of the surrounding membrane. In
fact, this ... muscarinic receptors, endo-
thelin receptors, rhodopsin) are located in lipid rafts
[65–70] where they are in close proximity to their
transducing GTP-binding protein (Gs, Gi, Go, Gq and
transducin...
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Báo cáo khóa học: The role of N-linked glycosylation in the protection of human and bovine lactoferrin against tryptic proteolysis pdf
Ngày tải lên :
30/03/2014, 13:20
... Properties of the iron-binding site of the N-terminal lobe of
human and bovine lactotransferrins. Importance of the glycan
moiety and of the non–covalent interactions between the N- and
C-terminal ... Archimedesweg, Leiden, the Netherlands
Lactoferrin (LF) is an iron-binding glycoprotein of the
innate host defence system. To elucidate the role of N-linked
glycosylation in protection of LF against proteolysis, ... such as the pancreatic
enzyme trypsin has been suggested [19,20].
The experiments described herein further elucidate the
role of N-linked glycosylation in the protection of lactofer-
rin against...
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