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role of adenosine in the control of inflammatory events associated with acute and chronic neurodegenerative disorders

Báo cáo y học:

Báo cáo y học: "The role of ATP and adenosine in the control of hepatic blood flow in the rabbit liver in vivo" pps

Báo cáo khoa học

... prosthesis inserted into the portal vein and the inferior vena cava of the in vivo rabbit model Figure Diagram of silastic H-shaped prosthesis inserted into the portal vein and the inferior vena cava of ... arterial and portal venous vascular networks of the rabbit liver: the role of adenosine Eur J Pharmacol 1997, 320:139-144 Mathie RT, Alexander B: The role of adenosine in the hyperaemic response of the ... relating the readings to the wet weight of the liver, determined at the end of each experiment The "buffering capacity" of the HA was expressed in % as: [Increase in HA flow / Decrease in PV...
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Báo cáo y học:

Báo cáo y học: " Solitary Peutz-Jeghers type hamartomatous polyps in the duodenum are not always associated with a low risk of cancer: two case reports" pptx

Báo cáo khoa học

... appearances of the polyp The most serious problem in PJS is an increased risk of cancer in the gastrointestinal tract The occurrence of cancer in the gastrointestinal tract has been reported in 20-25% of ... mucosa, with a focus of well-differentiated adenocarcinoma Hematoxylin and eosin staining (objective 10 ×) Figure Pedunculated duodenal polyp measuring 15 mm in diameter in the second part of the ... Figure Histological examination showed findings suggestive of a hamartoma without malignant components Hematoxylin and eosin staining (objective 10 ×) or sex of the patient, or the location, size...
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Báo cáo y học:

Báo cáo y học: " The first description of severe anemia associated with acute kidney injury and adult minimal change disease: a case report" ppsx

Báo cáo khoa học

... therapy was initiated on Day eight The hematocrit percentages and creatinine levels were measured at the indicated days The changes in hematocrit and creatinine levels correlated well with the progression ... raises the possibility that the early use of EPO may have facilitated the recovery of renal function In combination with the experimental data, our findings then support the notion that EPO, administered ... provided clinical information and critically reviewed the content of the paper EF interpreted patient data and the literature and critically reviewed the content of the paper All authors read and approved...
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Báo cáo khoa học: Production and utilization of hydrogen peroxide associated with melanogenesis and tyrosinase-mediated oxidations of DOPA and dopamine docx

Báo cáo khoa học: Production and utilization of hydrogen peroxide associated with melanogenesis and tyrosinase-mediated oxidations of DOPA and dopamine docx

Báo cáo khoa học

... peroxidase–H2O2 systems in later stages during the oxidation of indolequinone precursors of eumelanin and benzothiazinylalanine precursors of pheomelanin [5–10] Of considerable interest are recent ... enhance pigment formation by regulating Fig Comparison of the modes of action of tyrosinase and peroxidase in converting tyrosine to dopaquinone In the in vitro tyrosinase-mediated assays conducted, ... oxidized with catalase than without catalase These catalase-inhibited oxidations of DOPA and dopamine strongly implicate the involvement of H2O2 in the diphenolase activity of tyrosinase Insufficient...
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báo cáo hóa học:

báo cáo hóa học:" Shiftwork in the Norwegian petroleum industry: overcoming difficulties with family and social life – a cross sectional study" pdf

Hóa học - Dầu khí

... problems with social and family life, and is positively associated with having enough time to spend in these areas, irrespective of the type of work schedule This finding accords with the locus of control ... consisted of general information regarding the purpose of the study and their personal access code for completing the questionnaire The data were collected within the same two-week period in August ... shiftwork-related internal locus of control and engaging coping strategies would be associated with lower levels of reported problems with social and domestic life, irrespective of the type of work schedule In...
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Báo cáo y học:

Báo cáo y học: "Rho iso-alpha acids from hops inhibit the GSK-3/NF-κB pathway and reduce inflammatory markers associated with bone and cartilage degradation" ppt

Báo cáo khoa học

... Determination of the arthritic index: Each paw was evaluated on the basis of a 4-point ordinal scale: – no visible signs, – edema/erythema of a single joint or digit; – edema/erythema of joints; ... on the inhibition of GSK3 pathway Effect of2 Effect of RIAA on the inhibition of GSK3 pathway (A) GSK-3α was incubated with RIAA (0, 5, 25 and 50 μg/ml) and the kinase activity was determined ... IκB and causes the degradation of the complex, which permits the dissociation and nuclear translocation of NF-κB p50/p65 NF-κB in the nucleus binds to DNA and activates inflammatory genes and...
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Báo cáo y học:

Báo cáo y học: "An inventory of yeast proteins associated with nucleolar and ribosomal components" ppt

Báo cáo khoa học

... nucleolar and ribosomal biology In the second part of the study, the identified proteins are subjected to phylogenetic profiling, thereby providing insights into the evolution of the nucleolus and ... for the karyopherins alpha and beta (KAP95, SRP1) The Uso1p-related myosin-like protein (MLP1) is linked to the interior side of the nuclear envelope and nuclear pore It is proposed to act in the ... PRP3 and PRP4, the U2A snRNP protein LEA1, the U2 components PRP9 and HSH49, the U5 snRNP protein PRP8, and the Sm core proteins SMX2 and SMD3 Furthermore, we predict the nucleolar localization of...
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analysis of data on spontaneous reports of adverse events associated with drugs

analysis of data on spontaneous reports of adverse events associated with drugs

Tổng hợp

... (MHRA) and Commission on Human Medicines (CHM) of the UK and the Food and Drugs Administration (FDA) of the US therefore weigh the potential benefits of a drug against the harms, on the basis of the ... clean-up The clean-up include correcting misspellings of names of drugs and adverse events, finding all descriptions in the data that point to the same adverse event and recoding them into the Medical ... (2009) of another study with the same duration as above but focusing on ADRs occurring after hospitalization, involving one hospital and two of the authors of the above report (including others), the...
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Báo cáo sinh học:

Báo cáo sinh học: " Hepatitis B virus (HBV) genotypes in Egyptian pediatric cancer patients with acute and chronic active HBV infection" pptx

Hóa học - Dầu khí

... differences in the sizes of the genotype-specific bands The type-specific primers were designed on the basis of the conserved nature of those sequences within a genotype and on the basis of their poor ... conflicting results in this context In a study of chronic carriers in which, surprisingly, 50% of the patients were infected with genotype A strains and 50% were infected with genotype D strains, ... patients infected with genotype D strains had more severe chronic liver disease In contrast, Gandhe et al [27] could not find that genotype D influenced the outcome of chronic HBV infection in Indian...
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Báo cáo hóa học:

Báo cáo hóa học: " Hepatitis B virus (HBV) genotypes in Egyptian pediatric cancer patients with acute and chronic active HBV infection" ppt

Hóa học - Dầu khí

... differences in the sizes of the genotype-specific bands The type-specific primers were designed on the basis of the conserved nature of those sequences within a genotype and on the basis of their poor ... conflicting results in this context In a study of chronic carriers in which, surprisingly, 50% of the patients were infected with genotype A strains and 50% were infected with genotype D strains, ... patients infected with genotype D strains had more severe chronic liver disease In contrast, Gandhe et al [27] could not find that genotype D influenced the outcome of chronic HBV infection in Indian...
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Báo cáo khoa học: Role of calcium phosphate nanoclusters in the control of calcification pot

Báo cáo khoa học: Role of calcium phosphate nanoclusters in the control of calcification pot

Báo cáo khoa học

... [32] According to PONDRề predictions, the positions of PC sequences in the SPs in Table were, with the exception of the globular protein riboavin-binding protein (RBP), disordered, and had disordered ... describe the binding isotherms obtained previously for the b-casein 125 phosphopeptide in this pH range, and the same model was adapted to t the binding isotherm of OPN 1149 measured at pH 7.0 The ... osteopontin C Holt et al details of the model are provided in Doc S3 (see Supporting information) The Ca2+ binding isotherm of OPN 1149 was determined by measuring the concentration of free Ca ions with...
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Báo cáo y học:

Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" ppt

Báo cáo khoa học

... understanding of the roles of these co-repressor complexes and thereafter their roles in disease In summary cigarette smoke exposure reduced HDAC2 activity and the expression of mSin3a and Mi-2α in ... mSin3a and Mi-2 co-repressor complexes or their role in disease The reduction in mSin3a expression in the lungs of cigarette smoke-expose mice may reduce the capacity for the regulation of pro -inflammatory ... a role in the chronic enhanced inflammation in diseases seen in the lungs of COPD Cigarette smoke-exposure induces a relatively glucocorticoid unresponsive inflammatory response in the lungs of...
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Báo cáo y học:

Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" pdf

Báo cáo khoa học

... understanding of the roles of these co-repressor complexes and thereafter their roles in disease In summary cigarette smoke exposure reduced HDAC2 activity and the expression of mSin3a and Mi-2α in ... mSin3a and Mi-2 co-repressor complexes or their role in disease The reduction in mSin3a expression in the lungs of cigarette smoke-expose mice may reduce the capacity for the regulation of pro -inflammatory ... a role in the chronic enhanced inflammation in diseases seen in the lungs of COPD Cigarette smoke-exposure induces a relatively glucocorticoid unresponsive inflammatory response in the lungs of...
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Development of a Regional Risk Management Framework for APEC Economies for use in the Control and Prevention of Introduced Marine Pests

Development of a Regional Risk Management Framework for APEC Economies for use in the Control and Prevention of Introduced Marine Pests

Báo cáo khoa học

... Conclusions, including the results of the November 2001 Workshop Management Framework - Introd uced Marine Pests Management capabilities and approaches  APEC and the MRCWG have a role in liaising with ...  Within APEC little is known on the introduction of marine pests  Little practical information on measures to prevent introductions  Lack of knowledge in what individual countries are doing ... NACA to enhance the effectiveness of existing instruments within APEC  Institutional arrangements for managing the marine environment is fragmented in most economies  Baseline surveys to identify...
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Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt

Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt

Báo cáo khoa học

... binding ligand Sodium ions may still bind to the N373L mutant through coordination to the other ligands of the binding site (center I), but the binding becomes much weaker as emphasized by the ... translocation of H+ across the membrane [3,13,14] An essential feature in the proposed mechanism is the binding of Na+ ions from the cytoplasm at D203 and S382 including sites and their delivery into the ... carboxylation of the biotin group and binding of the carboxybiotin to the OadB site This step (Fig 4A,D) is supposed to restore the original conformation with the channel opening to the cytoplasmic...
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AN INCREASING ROLE FOR COMPETITION IN THE REGULATION OF BANKS doc

AN INCREASING ROLE FOR COMPETITION IN THE REGULATION OF BANKS doc

Ngân hàng - Tín dụng

... as the development of offshore financial centers and off-balance-sheet methods of financing); • the diminishing effectiveness of traditional controls due to financial innovation (including the ... to being changed and enforced in the interest of the regulated industry, rather than in the interest of the economy at large General laws, on the other hand, tend to be more immune and therefore ... 1980s In the case of S&Ls the insurance premium was set by statute in 1950 at 1/12 of 1% of the assessable deposits and was the same for all insured institutions regardless of the riskiness of their...
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Báo cáo khoa học: Roles of prolactin-releasing peptide and RFamide related peptides in the control of stress and food intake potx

Báo cáo khoa học: Roles of prolactin-releasing peptide and RFamide related peptides in the control of stress and food intake potx

Báo cáo khoa học

... neurons in the brainstem and hypothalamus, and induce neuroendocrine and behavioral responses Food intake also activates the brainstem and hypothalamus, resulting in the termination of meals and the ... SP9155) Decrease in vasopressin release Increase in the release of ACTH, oxytocin, vasopressin and prolactin Increase in the release of ACTH, oxytocin and prolactin ? ? No effects Increase [52,53] ... hypothalamus The administration of RFRP increases Fos expression in the hypothalamic paraventricular nucleus and in hypothalamic oxytocin neurons, and facilitates the release of ACTH and oxytocin into the...
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Báo cáo khoa học:

Báo cáo khoa học: "Some aspects of phytohormonal participation in the control of cambial activity and xylogenesis in tree stems" pot

Báo cáo khoa học

... correlated with the breaking of cambial dormancy (Little and Wareing, 1981Moreover, ABA content increases again in reactivating cambium, for example, in the trunk of Pinus contorta (Savidge and Wareing, ... peaking in late summer is rather incidental and drought-induced During winter, a decrease in the ABA level, often associated with an increase in conjugated ABA, is frequently reported, but these ... inactivation of auxin receptor and carrier proteins Later on, the breaking of rest may occur when the conditions of active membrane trans- port are regained Is abscisic acid (ABA) involved in the regulation...
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Báo cáo khoa học:

Báo cáo khoa học: "Does the surgeon still have a role to play in the diagnosis and management of lymphomas?" docx

Báo cáo khoa học

... University in the late 1960s which showed that the performance of a staging laparotomy altered the stage of disease in 42% of cases, up regulating in 28% and down regulating in 14% of cases [2] The ... baseline against which the effects of chemotherapy may be judged The aim of this study was to examine whether the 21st century surgeon still has a role to play in the diagnosis and management of ... perihepatic and perisplenic in addition to retroperioneal lymphadenopathy Thus upper gastrointestinal surgeons with training in these techniques may have an increasing role in the diagnosis of lymphomas...
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Báo cáo y học:

Báo cáo y học: "IV among pregnant women in Moshi Tanzania: the role of sexual behavior, male partner characteristics and sexually transmitted infections" pot

Báo cáo khoa học

... determine factors associated with incident HIV and sexually transmitted infections (STIs) in the postpartum period The information on determinants for HIV is intended to contribute in improving ... recruitment and activation of HIV susceptible inflammatory cells The inflammation and ulceration increases HIV shedding in the genital tract, thus the HIV infectiousness [10,11] HSV- and syphilis ... sector and the main income generating activities are tourism, trading and agriculture The present study was conducted in the two largest primary health care clinics, Majengo and Pasua These clinics...
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