rodent stressors and the stress response
Báo cáo khoa học: The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster Implications for cellulose synthase complex formation and oxidative stress response potx
... Fig The membrane binding loops The IAB loops of Anx(Gh1) (A) and AnxA5 (B) are shown in the same view from the front (C) and (D) show the IIAB loops of Anx(Gh1) and AnxA5, respectively, from the ... head-to-head The exposed tryptophan side chain is sandwiched between Arg261 and Tyr308, right between the AB and DE loops of the domain IV of the symmetry mate Compared to Anx24(Ca32), the tryptophan ... cations in the conformation found in the crystal structure Neither the first nor the other domains are able to coordinate cations in these regions, as positively charged residues in the close vicinity...
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Báo cáo khoa học: Relaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka pptx
... anterograde and retrograde tracers have shown that the NI, together with the median raphe and interpeduncular nuclei, may form a midline behavior control network, and many targets of the NI, such as the ... expressed in the PVN and SON [12,17,21] The structure and function of the relaxin family peptide receptors, including RXFP3 and RXFP4, were recently reviewed by Kong et al [22] Cont Stress B Stress ... sion and leads to an increase in relaxin-3 mRNA levels in the NI [12] On the other hand, relaxin-3-positive neurons project fibers to the hypothalamus, and RXFP3 is intensely expressed in the PVN...
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Báo cáo y học: "Stress, the stress response system, and fibromyalgia" ppt
... branches; sympathetic and parasympathetic These two divisions have antagonistic actions on most bodily functions and thus their proper balance preserves homeostasis The action of these two branches ... but varies from beat to beat constantly The antagonistic effects of the sympathetic and parasympathetic branches of the ANS on the sinus node harmonize the periodic components of this constant ... tested the response of FM patients to different stressors [13,18-21] The results are summarized in Table Diverse reports agree with the concept that subjects with FM have a deficient sympathetic response...
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Báo cáo y học: "Is fibromyalgia a cardiovascular disease? A comment on Martinez-Lavin’s review ‘Stress, the stress response system, and fibromyalgia’" ppsx
... Martinez-Lavin M: Biology and therapy of fibromyalgia: Stress, the stress response system, and fibromyalgia Arthritis Res Ther 2007, 9:216 Fontenele JB, Félix FHC: Fibromyalgia and related medically ... Arthritis Research & Therapy Vol No Félix and Fontenele Competing interests The authors cite their own work on the subject that is currently in press There are no potential sources ... and nociception modulation? J Musculoskeletal Pain, in press Stewart J, Taneja I, Medow MS: Reduced central blood volume and cardiac output, and increased vascular resistance during static handgrip...
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Báo cáo y học: "The organisation of the stress response, and its relevance to chiropractors: a commentary" pdf
... tubules of the kidneys Implications of the stress response on the body Everyday interactions with the environment inevitably expose the body to a wide range of stressful stimuli The stress response ... of the stress response via inhibitory control of the production and release of CRH and ACTH at the level of the hypothalamus and pituitary respectively, via transmitter systems projecting to the ... cingulate [29] and via the reticular activating system to the sensory cortex [30,31] The sensory cortex then directs information directly to the amygdala, or via the hippocampus and then to the amygdala...
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Báo cáo khoa học: Salicylic acid and the hypersensitive response initiate distinct signal transduction pathways in tobacco that converge on the as-1-like element of the PR-1a promoter pot
... expression through the same cis-acting element in the PR-1a promoter On the other hand, an as-1 containing PR-1a promoter responds differently from the wild-type promoter towards SA and the HR Therefore, ... to standard procedures [34] For the construction of the PR-1 reporter gene, a 0.27 kb StyI/PstI fragment from kW38-1, comprising parts of the 5¢ region and the open reading frame encoded by the ... containing the PR-1a gene The resulting plasmid was linearized with EcoRV, which cuts in the PR-1a 3¢ untranslated region 56 bp 3¢ to the stop codon, and a SacI linker was added to the blunt ends The...
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báo cáo khoa học: " Co-expression and promoter content analyses assign a role in biotic and abiotic stress responses to plant natriuretic peptides" pptx
... high and sustained after the stress has been removed and thus may indicate that the initial damage inflicted, and not the actual presence of the stress itself, is the driving force for the maintained ... specific to shoots in response to K+ starvation and osmotic stress and to roots in response to NaCl stress The expression correlation between AtPNP-A and the discussed WRKY genes and the overrepresentation ... expression of AtPNP-A, WRKY 70 and WRKY 46 and the average fold change for the 25 correlated genes in response to abiotic stresses (A) and biotic and chemical treatments (B) (A) The treatments were: UV-B...
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Báo cáo y học: "Science review: Extracellular acidosis and the immune response: clinical and physiologic implications" potx
... understanding of the relationship between pHo and the synthesis and release of inflammatory molecules Investigators continue to seek means to modulate the inflammatory response as primary therapy ... inflammatory mediators differently at different stages in their synthesis and release Little is known about the effects of HCl on other cytokines or on the kinetics of pHo mediated effects 332 Lactic acid ... literature on the effects of HCl on TNF synthesis [5–7] Furthermore, the paradox in which mild and severe acidosis induced by HCl results in opposite effects on NO has now been explained Pedoto and colleagues...
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Cross border mergers acquisitions and the legal response of host countries
... capital markets, the focus of their M&A regimes is to protect the interests of shareholders and the order and efficiency of capital markets; in most developing countries, on the other hand, host governments ... for the uneven development of these transactions all around the world In developed countries such as the US, the UK and the EC, either the largest target country or the largest acquirer where cross-border ... the relationship between the surviving company and the original merging parties The company that continues operating after the merger can either be the acquiring company assuming all assets and...
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Báo cáo khoa học: Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state pot
... catalase T and catalase A, did not alter the growth, either after the single treatments or after the associations of both treatments (Fig 1) On the other hand, the deficiency of sulfiredoxin, a low ... Oxidative stress responses of the yeast Saccharomyces cerevisiae Yeast 14, 1511–1527 Grant CM (2001) Role of the glutathione ⁄ glutaredoxin and thioredoxin systems in yeast growth and response to stress ... Yap1, Skn7 and cTPxI act in the same pathway in the response of yeast with dysfunctional mitochondria to oxidative stress Because cell growth was more affected by the deletion of YAP1 and SKN7...
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báo cáo khoa học: "The grapevine guard cell-related VvMYB60 transcription factor is involved in the regulation of stomatal activity and is differentially expressed in response to ABA and osmotic stress" ppt
... Subgroup 1, was more closely related to the grape protein accession ACF21938 than to the other members of the subgroup (AtMYB30, 31, 94 and 96) On the other hand, the grape accession protein ABK59040 ... found in the first intron and the third exon, which were longer in the grape genes compared to AtMYB60 Expression of VvMYB30 and VvMYB60 in grape tissues and in response to hormonal and stress ... Arabidopsis and grape MYB60 proteins and other closely related proteins from subgroup 1: a distinctive PHEEG signature in the MYB domain, located in the loop connecting the R2 and R3 repeats, and the...
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THE MECHANISMS REGULATING THE TRANSCRIPTION FACTOR ATF5 AND ITS FUNCTION IN THE INTEGRATED STRESS RESPONSE
... uORFs, and the white box overlapping uORF2 represents the 5′-portion of the ATF5 coding region The number of nucleotides between uORF1 and uORF2, and between the first residue of uORF2 and the ATF5 ... shutoff of protein synthesis Therefore, activation of GADD34 and the attendant dephosphorylation of eIF2α serve to provide a means for cells to attenuate the stress response once the stress damage has ... the ribosomes would scan through the inhibitory uORFs 2, 3, and During the interval between uORF4 and the GCN4 coding region, the scanning ribosomes would reacquire the eIF2 ternary complex and...
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SIGNALING MECHANISMS THAT SUPPRESS THE ANABOLIC RESPONSE OF OSTEOBLASTS AND OSTEOCYTES TO FLUID SHEAR STRESS
... anabolic response of bone cells to fluid shear stress through the suppression of anabolic bone gene expression Taken together, these data support the hypothesis that “STOP” mechanosomes exist and their ... interstitial fluid shear stress are seen across the surface of osteoblasts and osteocytes Mathematical models have estimated the physiologic range of fluid shear stress within the lacunae and canalicular ... study the metabolic response of endothelial cells to steady and pulsatile shear stresses (Frangos et al., 1988) The unidirectional model of fluid shear stress was used by many researchers in the...
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Tài liệu The Global economic crisis challenGes for DevelopinG asia anD aDb’s response ppt
... how and when the crisis reached them, the nature and intensity of its effects, and their ability to fight back East and Southeast Asian governments and central banks moved quickly to expand local ... healthy growth and demand in the developed world helped support Asia’s recovery This time, however, the US, Japan, and Europe the G3 countries—are in recession and their business confidence and consumption, ... pressure on their balance sheets than the rest of the world’s (Figure 2) The capital adequacy ratios of the banks in the region were strengthened after the Asian financial crisis and lending...
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Achieving sexual and reproductive health and rights for women and girls through the HIV response pot
... educate and involve men in matters pertaining to their and their partners’ sexual and reproductive health and rights, and to create safe and stigma-free access to abortions in the community The project ... with their partners, and to rely on their partners for drugs and supplies These factors reduce their ability to control whether sterile injecting equipment and condoms are used Violence, and the ... knowledge and understanding of the needs of women and girls33 to underpin the complex and nuanced intersections between HIV prevention, treatment and care, and sexual and reproductive health and rights...
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Báo cáo khoa học: The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco⁄endoplasmic reticulum calcium stores ppt
... of the autophagosome The machinery controlling formation of the autophagosome involves two ubiquitin-like conjugation systems The first is the conjugation of Atg12 to Atg5 [15] The other is the ... (z-RR)2-MagicRed-Cathepsin B substrate (MagicRed) HL-1 cells were treated with lysosomal inhibitors (PepA, E64d and Baf) in MKH buffer for h with MagicRed present during the last 30 of the experiment, and then ... Bcl-2 is found in the cytosol, at the mitochondria, and at the S ⁄ ER [37] Forced localization of Bcl-2 to the S ⁄ ER has previously been reported to suppress autophagy in response to nutrient...
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Báo cáo khoa học: Human skin cell stress response to GSM-900 mobile phone signals In vitro study on isolated primary cells and reconstructed epidermis docx
... 900 and 1800 MHz During a phone call, the mobile phone is placed on the ear and, thus, on the skin Maximum energy absorption takes place in the skin (half of the energy emitted by the phone) and ... at the ceiling of the cavity The dose absorbed by the irradiated object is constantly measured by a radiometer present in the apparatus, the measurement depending on the ageing of the lamp The ... placed at the centre of the cross-linker at a GSM-900 and cell stress in skin models distance of 13.5 cm (minus the height of the culture dish) from the UV lamp The apparatus calculates the duration...
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Báo cáo khoa học: The CssRS two-component regulatory system controls a general secretion stress response in Bacillus subtilis pdf
... trigger a secretion stress response, and that the CssRS-dependent response is a general secretion stress response Results Nontranslocated pre-AmyQ does not provoke a secretion stress response Previous ... stress than the htrA–lacZ reporter gene fusion [3,22] Therefore only the htrB–lacZ fusion was used as the preferred reporter of secretion stress in the further experiments of this study Fig The ... CssRS-dependent stress response, and that production of proteins other than a-amylases can also provoke this protein secretion stress response in B subtilis Therefore, we conclude that the CssRS-dependent response...
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Báo cáo khoa học: Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response potx
... SeV and VSV may have evolved strategies to antagonize polyamine synthesis and to evade the polyamine-mediated apoptotic FEBS Journal 272 (2005) 3120–3131 ª 2005 FEBS N Grandvaux et al response The ... enzymes, and ArgI is the hepatic-specific counterpart [16] The two isoforms possess the same enzymatic activity for converting l-arginine into l-ornithine and urea, a critical step in the polyamine ... (spermine, spermidine and putrescine) regulate numerous processes, including cell growth and differentiation, immune response regulation, and apoptosis [21] However, their role in the apoptotic process...
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FOOT-AND-MOUTH DISEASE RESPONSE PLAN THE RED BOOK potx
... This Foot -and- Mouth Disease (FMD) Response Plan: The Red Book (2012) incorporates comments received on the FMD Response Plan: The Red Book (2010) and FMD Response Plan: The Red Book (2011) and updates ... developing and preparing the FMD Response Plan, the U.S Government, U.S Department of Agriculture and the Animal and Plant Health Inspection Service and other parties, such as employees and contractors ... the plan The previously revised version of the FMD Response Plan (2011) was updated to reflect the comments made on the November 2010 version of the plan While much of the document remained the...
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