... and the mutants K13 3A, E142O, W14 0A and W140O areshown in Fig. 3, with their thermodynamic parameterssummarized in Table 1. The calorimetric DHcalvaluesFig. 1. CD spectra of wild- type and ... structure-based analysis of staphylococcal nuclease. Proteins: Structure, Function and Genetics 27, 171–183.15 Flanagan JM, Kataoka M, Fujisawa T & EngelmanDM (1993) Mutations can cause large changes ... of wild-type SNase andthe fourmutants E142O, K13 3A, W14 0A and W140O. The fluorescence spectra of E142O and K13 3A are similarto that ofthe wild-type protein. However, the fluores-cence in the...
... and therefore may serve as a standard of length; silver has actual intrinsic value, and may therefore serve as a standard of value: but the bill ofa Mutual Bank, having a legal value only, and ... standards or measures of value; and this fact is put forth as a recommendation ofthe mutual money to favorableconsideration. The SILVER DOLLAR is the measure and standard of value; andthe ... twofold way, and has therefore a twofold value anda twofold price,—onevalue as an article that can be exchanged for other commodities, and another value as anarticle. that can be loaned out at interest;...
... prevent.• Data manager changes data. A malicious data manager may change the value of its data on each cacherefresh. While this is an advantage for shared memory applications, it is a serious ... requested. The Mach kernel can only handle integralmultiples ofthe system page size in any one call and partial pages are discarded.Since the data manager may have external constraints on the consistency ... temporarily allow read-only access to cached data. The locking on a page may later be changed as deemednecessary by the data manager. [To avoid race conditions, the pager_data_provided call also...
... to war couldeasily work against ideas of restraint in war, a point dramatically illu-strated in India by the Arthas´astra of Kautilya. This was a manual of statesmanship – including the waging ... War and Imperialism, at 174.ARES AND ATHENA29CONTENTSPreface page xList of abbreviations xiIntroduction 1PART IWar as law enforcement (to 1600) 71 Ares and Athena 13Hallmarks of war ... at 59.65Ibid . at 79.30WAR ANDTHE LAW OF NATIONSany formal declaration.60Nor, apparently, was it thought necessary to have a formal declaration of war in the case of certain small-scale,...
... Hospital setting and antibiotic policy: NARP was initiated in Turkey in February 2003 by a central regulation of Ministry of Health and was announced nation-wide via official newspaper ofthe ... and Methods: The data obtained from all ofthe four university hospitals, and one referral tertiary-care educational state hospital in Ankara. Antimicrobial resistance profiles of 14,233 selected ... centres already apply-ing local antibiotic restriction policies the utilisation of many ofthe restricted antibiotics was decreased and the trend of resistance rates became downwards after implementation...
... control The way the knowledge transfer programme wasmanaged also differed between plants. The idea of the central programme management was that,at the least, plants should make yearly plans foreach ... differentKnowledge and Process Management CASE STUDYTransfer of Knowledge andthe Role of Motivation 123‘Merchandise’ such as printed T-shirts, armbands and baseball caps were distributed and furtheremphasized ... (production manager).Aspiration and strategic ambitionsBecause each plant investigated was run as a profitcentre and was normally measured (by corporateheadquarters) on operating margin and/ or returnon...
... INTEGRATIVE MEDICINE ANDTHE HEALTH OFTHE PUBLIC income, and behavioral risk factors. These factors, and others, impact health status, accentuate disparities, and can lead to costly, preventable ... publication, Integrative Medicine andthe Health ofthe Public: A Summary ofthe 2009 Summit, provides an account ofthe discussion and presentations ofthe two -and- a- half day summit in Washington, ... Gaudet, and Dr. Mike Magee each noted that the disease-oriented approach of conventional allopathic medicine neither naturally leads to the type of clinician-patient understanding Berwick and other...
... They decided again and again thatit was nothing, but just as often they again began wondering what it was .And the fear of making themselvesridiculous kept them of speaking of it to John.Jack's ... desk stood at the rear end of an aisle which ran nearly the length ofthe room, behind the rank of tellers' cages and in front ofthe vaults. At the other end ofthe aislewas the door which ... sidewalk and up the stairs, transferring him at the door to the care of Thomas Jones, the watchman."Call for me in about an hour, James. I shall have Ah, that gale is bitter! I shall have...
... 5¢-GGTATTGAGGGTCGCCATGGTTATGTTCAATCACCA-3¢; reverse primer, 5¢-AGAGGAGAGTTAGAGCCTTACAAGAAGGGTCCAAAGA-3¢). The PCRproduct was purified, treated with T4 exonuclease tocreate vector-compatible overhangs and annealed to a prepared ... CHB1.Degradation of a- and b-chitin The degradation rates of a- and b-chitin were assayedwith LlChi1 8A in the presence or absence of LlCBP3 3A. As both chitin variants, and especially a- chitin, are highly ... complemen-tary strategies to gain access to and degrade individualpolymer chains. First, the chains are degraded by bothendochitinases, that attack the chitin chain randomly, and exochitinases, that attack...
... modeled.Table S4. Average rmsd (A ˚) for the conserved catalyticresidues calculated from MD simulations of a- CT and the various Lac -a- CT conjugates modeled.This material is available as part ofthe ... mechanism of the enzyme.Structural insights into the mechanochemicalnature of a- CT catalysis A more detailed analysis ofthe influence of chemicalglycosylation on the dynamics of a- CT from the ... Kinetic quantitative analysis ofthe HX decay datawas done by a two-exponential model:X ¼ A 1expðÀkHX;1Þtþ A 2expðÀkHX;2Þtþ A 3where A 1, A 2, and A 3are the fractions ofthe fast,...