... biological gradient of longterm arsenic exposure with the prevalence of carotid atherosclerosis [6], further providing evidence ofthe presence ofatherosclerosisinduced by arsenic Despite the well-documented ... involved in atherosclerosis, possibly masking the role ofthe HO-1 genotype Gene polymorphisms of p53 and glutathionetransferase P1 (GSTP1) were related to theriskof carotid atherosclerosis in the ... possibility of other genes that confounded the relation between the HO-1 genotype and carotid atherosclerosis In the LMN cohort in the context of high arsenic exposure, the Page of 11 possibility of an...
... associated with theriskof CIN Acknowledgment Prof De Luca had full access to all the data in the study and takes responsibility for the integrity ofthe data andthe accuracy ofthe data analysis ... far few studies have investigated the role of uric acid in the occurrence of CIN Therefore, the aim ofthe current study was to evaluate whether high level of serum uric acid in patients undergoing ... no association between uric acid andthe extent of CAD [26] On the basis of this assumptions it might be supposed that the role of uric acid in the development of CIN could potentially represent...
... To our knowledge there are no other reports of a direct link between poultry consumption andriskof diabetes or of interactions between poultry consumption and BMI andtheriskof type DM Red ... in the association of unprocessed total meat intake and type DM risk depending on the BMI ofthe women A higher consumption of total unprocessed meat was related to a modest reduction in therisk ... decrease in riskof type DM in the NHS II [6] No association between poultry consumption andriskof type DM was found in the Health Professionals Follow-Up Study [7], the WHS [3], or the NHS I...
... degree of risk, andthe level ofrisk typically correlates with the return an investor can expect to receive Low risk generally means low yields, and high yields typically involve higher risk Fraud ... illiquid and difficult to value As a result, self-directed IRA custodians often list the value ofthe investment as the original purchase price, the original purchase price plus returns reported by the ... IRAs and steering them to custodians who offered the self-directed IRAs Approximately $3.5 million ofthe funds invested in the bonds came from self-directed IRAs SEC v Stinson Be mindful of “guaranteed”...
... in the amount of work they could perform, irrespective of whether they are limited in the kind of work they can perform (1 = yes, and = no) The vast majority of respondents who noted that they ... indicated whether the husband made less than 40% ofthe couple’s total income, andthe second dummy variable indicated whether the husband made more than 60% ofthe couples’ total income The omitted ... by the end ofthe study but were at riskof divorce until the study ended) The model I estimated is ofthe following general form and takes into account the fact that all eligible members of...
... to the percentage of energy as carbohydrate, the percentage of energy as animal protein, andthe percentage of energy as animal fat, andthe other was calculated according to the percentage of ... protein intake andthe highest carbohydrate intake) to 30 (the highest protein and fat intake andthe lowest carbohydrate intake) Therefore, the higher the score, the more closely the participant’s ... multiplying the carbohydrate content of each food by its glycemic index (the glycemic index of glucose is 100) and then multiplied this value by the frequency of consumption and summed these values...
... and promote inflammation in the absence of free TNF ligand.6 Nonetheless, only a few studies have examined the relationship between levels of sTNF-R1, sTNFR2, and interleukin-6 andtheriskof ... pool the estimates of relative risk for men and women, we used the weighted average of estimates according to the random-effects model of DerSimonian and Laird.24 All P values are two-tailed, and ... association between the levels of soluble TNF-a receptors andtheriskof coronary heart disease (Table 3) Men in the highest quintile of interleukin-6 had a 57 percent increase in theriskof coronary...
... fracture risk Furthermore, the degree ofrisk or nonrisk in a particular patient cannot be accurately estimated from any combination ofthe identifiable risk factors for osteoporosis and/ or common ... already at risk because of established glucocorticoid -induced osteoporosis, bisphosphonates have the capacity to restore bone mass and thus reduce theriskof vertebral fracture.3 They are currently ... Bisphosphonates and calcium should not be taken at the same time of day because the calcium impairs absorption ofthe bisphosphonate Therapeutic Tactics It is important that the daily dose of ICS be...
... included hand X-rays to assess efficacy Application of such automated radiogrammetry to the existing clinical trial data (such as these hand X-rays) offers an opportunity to examine the effects of TNF ... needed to fully evaluate the effect of TNF blockers in this regard An interesting observation here is that the availability of automated radiogrammetry means that the effect of TNF blockers on BMD ... were small and non-significant Serum osteocalcin rose andthe resorption marker urinary deoxypyrdinoline decreased Most of these reports have been with infliximab It is unclear whether a similar...
... most analyses of observational studies reported an increased riskof infection, which conflicts with the result ofthe RCTs The dose of GC therapy varied both within and between RCTs and observational ... inverse ofthe variance ofthe logarithm ofthe odds ratio) to the definition of infection (for example, serious or not serious), alternative weighting was performed by number of patients, then ... Ten of 21 studies had no reported infections in either arm, and four further studies had no infections in one ofthe two arms The estimated relative riskof infection associated with GC therapy...
... Ascertainment ofthe blood transfusion exposure For the ARDS cases, the pRBC transfusions were examined in the time period prior to or at the visit ofthe first recorded ARDS complication For the control ... http://ccforum.com/content/11/3/R63 ately preceding the visit with the onset of ARDS, and (ii) for the No ARDS group, we used the highest SOFA score observed in the ICU (that is, the worst condition) Statistical ... increased riskof ARDS Whereas severity of illness, baseline hemoglobin, and hypoalbuminemia were each significant risk factors for ARDS development, the magnitude ofthe association with ARDS and...
... increased theriskof gastric atrophy [18] Table shows the age-sex-adjusted ORs ofthe Gab1 andthe combinations of PTPN11 and Gab1 genotypes for gastric atrophy among seropositive healthy controls The ... diagnosis of cancer In summary, the Gab1 A/A was associated with the low riskof H pylori infection while the G/A and A/A genotypes together may increase therisk for gastric atrophy The biological ... eradication ofthe bacteria However, the OR ofthe A/A genotype for H pylori seropositivity was 0.25 (95% CI 0.09-0.71) So, the Gab1 polymorphism was associated with the low riskofthe infection...
... main safeguards in place, and concludes that there may be a need to reconsider some of them in view ofthe growing role of nonbanks andofthe global reach of risks in the electronic era Introduction ... the case in several European countries), compliance risk may arise if the rules and management ofthe payment scheme not comply with the regulatory standards • Riskof illicit use: theriskof ... Therisk elements are then viewed in the context of other company-specific factors, such as the state of current control (i.e., the security baseline); the sophistication of vulnerabilities and...
... 4) The R2 ofthe full model is 17.24%, i.e the combined contribution ofthe systematic factor andthe regulation to the total timely variation ofthe exposure is 17.24% and, therefore, 82.76% of ... instance, the duration, andthe weighted sum ofthe positions’ duration is a measure ofthe bank’s exposure to interest rate risk (See, for instance, Sierra and Yeager (2004)) The main problem of these ... correlation between the earnings from term transformation andtherisk premia on loans In times of a boom the term structure tends to be steep andtherisk premia (and thereby the mark-up) tend...
... or risk index Scope ofrisk G Scope ofriskand details of possible events, including description ofthe events, their size, type and number Nature ofrisk G Classification of risk, timescale of ... rank the key risks for further analysis Risk classification systems An important part of analysing a risk is to determine the nature, source or type of impact oftherisk Evaluation of risks ... 1: Risk, risk management and ISO 31000 Nature and impact ofrisk Principles ofrisk management Review of ISO 31000 Achieving the benefits of ERM Part 2: Enterprise risk management Planning and...
... central nervous system, andthe lack of induction of inflammatory responses [22] Despite a long-standing interest in the field of muramyl peptides, the impact of these molecules at the mitochondrial ... approved by the Institutional Animal Care and Use Committee ofthe University of Balamand and complied with the principles of laboratory animal care Chemicals and reagents Muramyl peptides (MDP and MB) ... immunomodulators to reveal the mechanism of action of toxic MDPs on mitochondrial respiration by correlating the uncoupling effect induced by these molecules with the level and function of UCP2 and free radical...
... makers and governments on the one hand and scientific researchers, medical and health professionals, patient groups, environmental organisations andthe public on the other We work to highlight the ... However, all the established risk factors together can only explain about half of breast cancer cases and for the remainder, scientists and doctors are still unsure ofthe causes2,3 One ofthe suggested ... theof cial views ofthe funders andthe EU institutions Factors influencing theriskof breast cancer – established and emerging April 2008 Introduction Most of us will know of someone affected...
... then returned to the apparatus and participated in a 5-min retention session in the presence -8- ofthe familiar object andthe novel object The time spent exploring the familiar and novel objects ... On the day ofthe tests, betaine was administered 30 before the start ofthe tests (Fig 1A) Proinflammatory molecules and glial activation are important for the pathogenesis of LPS -induced memory ... Immediately after the familiarization session, the mice were removed from the apparatus, and one ofthe familiar objects was randomly replaced with a novel object (triangle pole) The mice were then returned...
... ofthe study andthe editing ofthe article BR contributed to shaping ofthe article andthe editing ofthe article GEE contributed to the statistical analyses andthe editing ofthe manuscripts ... a given predictor, and an outcome in the units of measurement ofthe predictor It is the change in the outcome associated with a unit change in the predictor, whereas the standardized regression ... diagnosis of either LQTS or HCM, recent SCD in the family) entered at step ofthe model accounted for 24% ofthe variance in physical health Increasing age (p < 0.01) and clinical diagnosis of either...
... depression, and odor of acetone on the breath Endometritis was diagnosed weeks postpartum by examination by the authors and diagnosed by the presence ofthe following clinical signs: cloudy discharge and ... compared using the chi-square test Evaluation ofthe effect of retained placenta on the occurrence of reproductive and metabolic disorders Cows were grouped based on the occurrence of retained placenta ... during the warm season for the first lactation and during the cold season for the second lactation Cow parity and calving season were eliminated from the final model since they did not influence the...