retailers expected one period cost and the mm s profi
Induction of anti tumor response by dendritic cell based vaccination
Ngày tải lên :
16/09/2015, 15:54
... this regards, exogenous antigen gains access to MHC class I presentation pathway instead of conventional MHC class II pathway Both CD8α- and CD8α+ DC subsets possess the ability to cross-present ... cells and peritoneal macrophages have been reported to express the message for the Flt-3 [109] In mouse BM, expression is restricted to blast cells, monocytes and a small subsets of lymphocytes ... its respective components It is postulated that the transfected cells will express and secrete the muc-1 fusion protein, thereby allowing uptake by DC, which will then process and present the...
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Báo cáo y học: "Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection" pdf
Ngày tải lên :
13/08/2014, 05:21
... into the second decade of infection in these 13 individuals, but this study also demonstrates the importance of host immune responses in sustaining this non-progressive disease course into and beyond ... responses, regardless of the strength and breadth of the CTL response A decline in this protective p24 response preceded or correlated with loss of non-progressor status and/ or signs of disease progression ... proliferative Immunovirological status the surviving non-progressors, 400, and Ultrasensitive assay, limit of detection (data by separately); Immunovirological status of the surviving non-progressors, showing...
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More Show Me How: Everything We Couldn't Fit in the First Book Instructions for Life from the Everyday to the Exotic Perfect Paperback
Ngày tải lên :
15/01/2014, 12:15
... crosswise pin Slide screw beneath keys Staple screw in place Play with thumbs 91 92 face the world as a flapper be a swell ’4 0s bombshell Lengthen and darken brows with a pencil Sweep on subtle ... ends of suitcases Cover the holes with stickers Arrange a distraction; sneak on the train Set up with the holes facing each other Climb up and close yourself in Stay quiet during the ride During ... spirits Just the two of you in town? Grab a witness off the street A rip in the veil brings good luck The pieces of a broken glass symbolize the many happy years ahead 167 Pay the officiant in cash...
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Tài liệu Báo cáo khoa học: Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers ppt
Ngày tải lên :
21/02/2014, 00:20
... the eEF1A sequence Possible methylation sites are shown and assigned based on the observed mass values, eEF1A sequence and previously published results [25] Peptides originating from trypsin autoproteolysis ... only the nucleolin band was evident Similarly to this and to the previous results [12], in the UV cross-linking assay the specific CRC displayed by the nuclear extract was not present in the cytoplasmic ... incubation, the filter was rinsed and then exposed to Omat XAR Kodak film, as described in the Materials and methods The same samples were used for Western blotting analysis performed with the same amount...
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Báo cáo khoa học: Protein kinase Ch activity is involved in the 2,3,7,8tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line potx
Ngày tải lên :
23/03/2014, 13:20
... was confirmed by restriction enzyme digestion and sequencing analyses at all the steps involved in subcloning by using standard procedures Transient transfection assay Plasmid DNAs were transfected ... vitro assays N-myristoylation of such synthetic PKC-specific pseudosubstrate peptides permits their use as selective, cell-permeable inhibitors of PKC in intact cells [26] Therefore, we examined the ... at the N terminus and HindIII at the C terminus was subcloned into pMACSKK.II Then, PCR was performed to create XhoI at the N terminus, upstream of the start codon, and SalI at the C terminus,...
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báo cáo hóa học:" Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells" pdf
Ngày tải lên :
18/06/2014, 15:20
... response [12,23-25] There is evidence of several protocols for loading DCs, based on the use of tumor antigens such as peptides, lysed tumors, whole proteins, and genes expressed on plasmids ... DCs to generate significant and specific CTL responses against HCMV antigens Several HCMV proteins have been shown to serve as target antigens for the class Irestricted CD8+ T cell responses ... coordination and revised the manuscript NG participated in the design of the study and revised and drafted the manuscript KB participated in the design of the study and revised and drafted the manuscript...
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báo cáo hóa học:" Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients" pot
Ngày tải lên :
18/06/2014, 15:20
... forms a complex with the chromosomal passenger proteins during mitosis and regulates mitotic progression In contrast, the protein levels as well as the mRNA levels of survivin-2B and other survivin ... tisExpression of survivin mRNA as assessed by RT-PCR in normal tissues, and oral cancer cell lines and primary oral cancer tissues (A) Expression of survivin mRNA in oral cancer cell lines and ... the expression levels of survivin or survivin-2B proteins in the tumor tissues As shown in Table 1, survivin expression was detected in all the cases by immunostaining Though there were some differences...
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báo cáo hóa học:" Regulatory activity of azabisphosphonate-capped dendrimers on human CD4+ T cell proliferation enhances ex-vivo expansion of NK cells from PBMCs for immunotherapy" potx
Ngày tải lên :
18/06/2014, 15:20
... biological studies and experiments and wrote the manuscript MP performed biological experiments OR synthesized the dendrimers used in this study COT designed and synthesized the dendrimers JJF designed ... Progression of cellular mean fluorescence intensity was analysed using modelling software (SAAMII, v1.2, University of Washington) Statistical analysis Statistical analyses were carried out using the ... NK cells relies notably on their ability to sense the decrease/absent expression of MHC-I molecules on their target ("missing-self model") [5,6] In humans, this sensing is controlled by a set of...
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Báo cáo hóa học: " A quantitative real time PCR method to analyze T cell receptor Vb subgroup expansion by staphylococcal superantigens" doc
Ngày tải lên :
18/06/2014, 16:20
... experiments (n = 9) A) Classic SEs and TSST-1 B) Novel SEs and SEls Table Comparison of Vb specificity observed in this study with those in selected previous studies SAgs Vb specificity observed ... Vb subgroup was expanded by one or more SAgs used in this study As shown in Table 4, the Vb specificities of SAgs observed in this study were very similar to those described in previous studies ... variants of SEC (SEC1, SEC2, and SEC3) were recognized [7] Through improvements in genomic analysis tools, novel SEs and SEl toxins including SEG, SElH, SEI, SElJ, SElK, SElL, SElM, SElO, SElP, SElQ,...
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Báo cáo hóa học: "Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: Differing impact on CD8 T cell phenotype and responsiveness to restimulation" pot
Ngày tải lên :
18/06/2014, 16:20
... cells showed a similar, albeit less marked, trend In these studies, only cells rested > 30 days between stimulations demonstrated substantial expansion relative to control cells In sum, these studies ... 0.005 P < 0.05 *The results represent the mean ± SE for matched pairs of cultures with the number of experiments marked in parentheses Paired t-test was used to assess significance The phenotype ... beads can be used to expand functional T cells, and that some of these cells can persist in vivo postinfusion While these results are encouraging, the bead expansion technique has limitations Ex...
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Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc
Ngày tải lên :
18/06/2014, 16:20
... properties towards various immune cell subsets and their defects are thought to contribute to many autoimmune disorders Strong evidence shows that IL-2 is one of the important stimulatory signals for ... contributes to intra-islet Treg cell dysfunction and progressive loss of self-tolerance in the islets As discussed above, the increased transcriptional activity of protective Idd3 alleles translates ... effects on all T cells, including pathogenic CD4 + and CD8+ Teff cells For the past decade, IL-2 has been used in the treatment of several diseases where the immune system necessitates strengthening...
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Báo cáo sinh học: " Thottapalayam virus is genetically distant to the rodent-borne hantaviruses, consistent with its isolation from the Asian house shrew (Suncus murinus)" potx
Ngày tải lên :
18/06/2014, 18:20
... oxidation-reduction homeostasis [17] insight into the long evolutionary history of the hantaviruses, and the development of specific diagnostic assays should provide the means to assess the potential public ... IEID fellowship to this work The findings and conclusions in this report are those of the authors and not necessarily represent the views of the funding agencies References TPM virus was isolated ... Asian house shrews captured in Indonesia [8] However, no virus or sequences were obtained from these specimens, so while these data point towards the presence hantaviruses in India, Thailand and...
- 5
- 406
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Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt
Ngày tải lên :
18/06/2014, 19:20
... transected along the LAD ligature to separate ischemic tissue and remote myocardium Heart tissues were lysed in lyses buffer Western blot analysis was performed using procedures established in our ... significant Result Expression and purification of PEP-1-SOD1 and PEP-1-CAT fusion protein pET15b-SOD1-His, pET15b-PEP-1-SOD1-His, pET15bCAT-His and pET15b-PEP-1-CAT-His were successfully expressed and ... and evaluated the apoptosis by Flow Cytometry YL and SYC analyzed the results and help writing the manuscript All the authors have read and approved the final manuscript Competing interests The...
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Báo cáo hóa học: " Thottapalayam virus is genetically distant to the rodent-borne hantaviruses, consistent with its isolation from the Asian house shrew (Suncus murinus)" pdf
Ngày tải lên :
20/06/2014, 01:20
... oxidation-reduction homeostasis [17] insight into the long evolutionary history of the hantaviruses, and the development of specific diagnostic assays should provide the means to assess the potential public ... IEID fellowship to this work The findings and conclusions in this report are those of the authors and not necessarily represent the views of the funding agencies References TPM virus was isolated ... Asian house shrews captured in Indonesia [8] However, no virus or sequences were obtained from these specimens, so while these data point towards the presence hantaviruses in India, Thailand and...
- 5
- 316
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Báo cáo hóa học: " Impairment of the CD8+ T cell response in lungs following infection with human respiratory syncytial virus is specific to the anatomical site rather than the virus, antigen, or route of infection" pdf
Ngày tải lên :
20/06/2014, 01:20
... asphyxiation The nasal turbinates and lung tissues were isolated and homogenized, and viruses were titrated in MDCK cell monolayers Analysis of CTL response Kinetics of the virus-specific CTL response ... 28, the percentages of virus-specific cells were reduced substantially in both the lungs and the spleen, although in the lungs, the reduction for the influenza virus-specific cells was less than ... of virus-specific IFNγ + CD8+ T cells in the lungs versus the spleen after respiratory and non-respiratory infections We used two respiratory viruses, RSV (strain A2) and influenza virus A/Puerto...
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Báo cáo hóa học: " Characterization of the IFN-γ T-cell responses to immediate early antigens in humans with genital herpes" doc
Ngày tải lên :
20/06/2014, 01:20
... S S W W W W S S S S S W W W S S S W S W S W W W W W W W W S S W S W S W W W W W W W S W W S W S S W S W S W S W S S S S S S S W S S Page of 15 (page number not for citation purposes) Virology ... L HSV-2/HSV-1 HSV-2/HSV-1 HSV-2/HSV-1 HSV-2/HSV-1 HSV-2 HSV-1 HSV-2 HSV-2 HSV-1 HSV-2/HSV-1 HSV-2 HSV-2 HSV-2 HSV-2/HSV-1 HSV-2 HSV-1 HSV-2 show a clear trend relative to serostatus Thus, stronger ... T-cells and also because of the ease to which positive responses can be narrowed to single peptides The results The ability to measure both CD8 and CD4 responses in unexpanded samples makes the assays...
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báo cáo hóa học:" Metabolic and anthropometric parameters contribute to ART-mediated CD4+ T cell recovery in HIV-1-infected individuals: an observational study" potx
Ngày tải lên :
20/06/2014, 08:20
... revision XY was responsible for statistical analysis, and contributed to data discussion and manuscript revision NJC was responsible for lipid assessment, and contributed to critical analysis, ... cytometer and analyzed using CellQuest software (BD Biosciences) Isotype-matched control antibodies were used as negative controls for gate positioning Statistical analysis Summary statistics (mean, standard ... Johannesburg, South Africa Authors’ contributions LA was responsible for study design, data management, data analysis, and manuscript and illustration preparation ASF supervised the statistical...
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Báo cáo sinh học: "Life and death as a T lymphocyte: from immune protection to HIV pathogenesis" doc
Ngày tải lên :
06/08/2014, 19:21
... distinct branches of the immune system, and it is not obvious how this could reflect a simple homeostatic response to the loss of CD4+ T cells It is also difficult to reconcile with the observation ... decreased numbers, perhaps because of different assays used to measure the size of this compartment Furthermore, in correlating disease progression with Tregs, the measure of Tregs that is used (for ... has been associated with disease progression [5,6] HIV can also indirectly cause innate immune stimulation because the infection results in damage to the integrity of mucosal surfaces and the...
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Tìm thêm:
- hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam
- xác định các mục tiêu của chương trình
- xác định các nguyên tắc biên soạn
- khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn
- khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản
- khảo sát chương trình đào tạo gắn với các giáo trình cụ thể
- xác định thời lượng học về mặt lí thuyết và thực tế
- tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam
- điều tra đối với đối tượng giảng viên và đối tượng quản lí
- điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1
- khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam
- khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu
- nội dung cụ thể cho từng kĩ năng ở từng cấp độ
- xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct
- phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ
- mở máy động cơ lồng sóc
- mở máy động cơ rôto dây quấn
- các đặc tính của động cơ điện không đồng bộ
- hệ số công suất cosp fi p2
- đặc tuyến hiệu suất h fi p2