regulation of vasculogenesis and angiogenesis
Regulation of navigation and vessel-source pollution in the Northern Sea Route - Article 234 and state practice
Ngày tải lên :
01/11/2013, 09:20
... 15 of the Economic Zone Edict; Arts and 15 of the Environmental Edict; and Art 11 of the Decree of the Council of Ministers of the USSR, June 1990, ‘On Measures of Securing the Implementation of ... owner of a vessel registered with a state party and carrying over 2,000 tons 87 88 89 90 91 92 94 95 See Arts 1(4), and 7(4) of the NSR Regulations; Art 14 of the Economic Zone Edict; and Art of ... shall establish periods and areas closed for navigation, and also other measures ensuring the safety of shipping and the prevention, reduction, and control of pollution of the marine environment...
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Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc
Ngày tải lên :
16/02/2014, 09:20
... tumorigenesis and genetic diseases [47] Most analyses of the regulation of AP-2 and the interactions of the transcription factor with binding partners, as well as of the regulation of target gene ... treatment of the chick face with RA, and this is accompanied by an increase in apoptosis [73] The authors of this study ascribe the regulation of outgrowth of limb buds and patterning of the digits ... A.-K Wenke and A.-K Bosserhoff stage of development They found that AP-2a, AP-2b, AP-2c and AP-2e are differentially expressed during the preimplantation period, and, with the exception of AP-2a,...
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Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx
Ngày tải lên :
07/03/2014, 01:20
... polymerases and components of the transcription machinery in the nucleus The role of actin in transcription and its regulation Actin is both a major cytoskeletal component of all eukaryotic cells and ... component of pre-mRNP particles, and is incorporated into pre-mRNAs by binding to a specific subset of RNA-binding proteins [4,22]; and (h) actin is a component of PICs and depletion of actin prevents ... actin monomers and prevents Rho-dependent nuclear accumulation of MRTF-A and SRF Actin and ABPs in transcription regulation activation [46], blocks the nuclear accumulation of MRTF-A and -B in the...
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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx
Ngày tải lên :
23/03/2014, 07:20
... nucleus Regulation of gene expression by HIPPI Caspase Nuclear pore complex HIP1 Fig Possible mechanisms of regulation of transcription and apoptosis by HIPPI and HIP-1 in HD Interaction of HIP-1 ... transcription caspase-6, and caspase-3 Cleavage of Bid and release of cytochrome c and apoptosis-inducing factors from the mitochondria are also observed Coexpression of wild-type htt exon and Hippi decreases ... models, brains of transgenic animals, and post-mortem brains of HD patients [2] Aggregate formation is enhanced with the increase in the number of glutamines in vitro and in vivo, and is believed...
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Báo cáo Y học: Molecular characterization of MRG19 of Saccharomyces cerevisiae Implication in the regulation of galactose and nonfermentable carbon source utilization pdf
Ngày tải lên :
31/03/2014, 08:20
... (Fig 10, lane and 2) and wild-type (Fig 10, lane and 4) strains bearing multiple copies of MRG19 and grown in the presence of glucose (Fig 10, lane and 3) and glycerol (Fig 10, lane and 4) It is ... Expression of Mrg19p as a function of cell density Wild-type cells transformed with multiple copies of MRG19 (lane and 3) and wild-type cells (lanes and 5) were allowed to grow to an OD600 of 0.5 and ... we monitored the rate of oxygen uptake in log and stationary phase cultures of wild-type and MRG19 disruptant cells The rate of oxygen uptake was increased in wild-type and MRG19 disruptant cells...
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VASCULOGENESIS AND ANGIOGENESIS – FROM EMBRYONIC DEVELOPMENT TO REGENERATIVE MEDICINE doc
Ngày tải lên :
27/06/2014, 18:20
... EPCs and their role in diabetic vascular diseases The role of vasculogenesis and angiogenesis in cancer is highlighted by two chapters that reveal the power of animal models and inhibitors of vasculogenesis ... processes, vasculogenesis and angiogenesis Endothelial cells are fundamental and common to both processes: however they differ in location, mechanisms of initiation and source of precursor cells Vasculogenesis ... of vasculogenesis at this gestational age The coexistence of budding vessels suggests the early onset of angiogenesis; nevertheless the rarity of this phenomenon indicates the prevalence of vasculogenesis...
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Báo cáo y học: "α Impact of VIP and cAMP on the regulation of TNF-α and IL-10 production: implications for rheumatoid arthritis" pps
Ngày tải lên :
09/08/2014, 01:23
... presence of VIP (lane 2), and that the combination of VIP and rolipram activates both CREB and ATF-1 upon LPS stimulation (lane 3) α VIP fails to modulate T-cell production of IL-10, TNF-α, γ and ... mouse, the augmentation of IL-10 and downregulation of TNF-α and IFN-γ results in a Th2 cytokine profile that is dependent on cell types present, differentiation status, and the activation stimulus ... cells, and synovial cells — all of which play an important role in the pathology of RA — and compare the findings with murine VIP data already published Materials and methods Reagents Capture and...
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Báo cáo y học: "T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFκB: implications for rheumatoid arthritis" docx
Ngày tải lên :
09/08/2014, 08:23
... concentrations of the following: 25 ng/ml TNFα (gift from Dr W Stec, Centre of Macromolecular Studies, Lodz, Poland), 100 ng/ml IL-6 (gift from Dr P Ramage, Sandoz, Pharma Ltd., Basel, Switzerland) and ... production of high levels of chemokines in M-CSF-differentiated human monocytes (macrophages) Levels of both CC chemokines (MCP-1, MIP-1α, MIP-1β and RANTES) and CXC chemokines (IL-8, GROα and IP-10) ... RANTES and MCP-1 was unaffected (Figure 2c) This inverted pattern of utilization of NFκB for the T-cell contact-dependent induction of CC and CXC chemokines in monocytes is surprising and indicates...
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Báo cáo y học: "Composition and regulation of maternal and zygotic transcriptomes reflects species-specific reproductive mode" doc
Ngày tải lên :
09/08/2014, 20:22
... ranking of IGR length between chicken and human, and another for its fold change between mouse and human Comparison of fold changes of all-maternal one-to-one orthologs versus the set of all one-to-one ... Materials and methods) To compare the relative contribution of post-transcriptional regulation among different classes of maternal transcripts, we used the length of the 3' UTR as an estimate of the ... strict-zygotic, P < 10-4 and P < 10-3; the genome-wide set of all core and metazoan genes, P < 10-21 and P < 10-72) Similarity in regulatory architecture of maternal and zygotic genes across...
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Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington’s disease pps
Ngày tải lên :
10/08/2014, 05:21
... to food and water ad libitum Both the housing and experimental use of animals followed the National Institutes of Health guidelines and were approved by the Institutional Animal Care and Use ... WTs and R6/2s indicate saline treatment, and WTc and R6/2c indicate ceftriaxone treatment N refers to number of animals per group Genotype and CAG repeat length We used PCR for genotyping and ... analyses and genotyping, and helped with data interpretation BRM participated in study design, and helped with data collection and analysis GVR conceptualized and designed the study, and revised...
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Báo cáo y học: "Regulation of apoptosis and priming of neutrophil oxidative burst by diisopropyl fluorophosphate" pps
Ngày tải lên :
11/08/2014, 03:20
... on apoptosis and priming of oxidative burst activity We report differential effects of DFP on neutrophil apoptosis and priming of oxidative burst activity, reflected in suppression of constitutive ... adding 70 μL of 2.8 mM TMB in PBS and 60 μL of mM hydrogen peroxide After minute of incubation at room temperature, the reaction was blocked with 50 μL of stop solution (500 μL of 10 mM sodium ... μg/mL) and analyzed using a BD FACS CANTO Flow Cytometer Data were analyzed using BD FACS DIVA software A minimum of 10 000 events were collected and analyzed at excitation wavelength of 488 nm and...
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Báo cáo y học: "Regulation of apoptosis and priming of neutrophil oxidative burst by diisopropyl fluorophosphate" pptx
Ngày tải lên :
11/08/2014, 06:22
... on apoptosis and priming of oxidative burst activity We report differential effects of DFP on neutrophil apoptosis and priming of oxidative burst activity, reflected in suppression of constitutive ... adding 70 μL of 2.8 mM TMB in PBS and 60 μL of mM hydrogen peroxide After minute of incubation at room temperature, the reaction was blocked with 50 μL of stop solution (500 μL of 10 mM sodium ... μg/mL) and analyzed using a BD FACS CANTO Flow Cytometer Data were analyzed using BD FACS DIVA software A minimum of 10 000 events were collected and analyzed at excitation wavelength of 488 nm and...
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Báo cáo y học: "Gene expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified by iloprost infusion" potx
Ngày tải lên :
12/08/2014, 14:22
... accurate detection and enumeration of rare events in flow cytometry are the number of events acquired and the signal to noise ratio Collection of a large number of events is mandatory to identify ... genes and 1,247 up-regulated genes) (Additional files 4, 5) These data showed that the transcriptional profiles of CECs in SSc were profoundly different from the transcriptional profiles of CECs of ... Comparison of CECs and EPCs levels between healthy controls and patients affected by SSc with and without ulcers were performed by T-test and Pearson test Correlations between CECs and EPCs number...
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Báo cáo y học: "Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease" potx
Ngày tải lên :
13/08/2014, 13:20
... PPAR ligands seen in pre-clinical models of efficacy and safety in the context of human health and disease Peroxisome proliferator-activated receptors: structure, ligands, expression and target ... PPARα ligands such as Wy-14,643, ciprofibrate and clofibrate are known to produce peroxisome proliferation and liver tumors in rats and mice [75,76] However, since PP belong to the class of carcinogens ... Pennie W, Hedley K, Soames A, Kimber I and Roberts RA Downregulation of Lactoferrin by PPARalpha Ligands: Role in Perturbation of Hepatocyte Proliferation and Apoptosis Toxicol Sci 2002, 68:304-313...
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pelaez - regulation of banks and finance; theory and policy after the credit crisis (2009)
Ngày tải lên :
03/11/2014, 19:19
... a model of linear demand and supply and a 10.1057/9780230251250 - Regulation of Banks and Finance, Carlos M Peláez and Carlos A Peláez The Theory of Regulation and Finance 31 rectangle of gain ... and services by a system of simultaneous equations of demand functions by consumers, supply functions by producers, and identities of demand and supply The arguments of the demand functions of ... 10.1057/9780230251250 - Regulation of Banks and Finance, Carlos M Peláez and Carlos A Peláez The Theory of Regulation and Finance The sum of the inequalities results in the left-hand side of prices multiplying...
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Epigenetic regulation of normal and malignant hematopoiesis
Ngày tải lên :
05/09/2015, 11:25
... mSin3A and HDAC1 in MEL and human T-ALL cells was linked to transcriptional repression and inhibition of erythroid differentiation (Huang and Brandt, 2000) The association between TAL1/SCL and mSin3A/ ... normal hematopoiesis and leukemia The methylation of histones on lysine and arginine residues by HMTs represents another level of gene regulation, and is probably the most complex of the epigenetic ... and more than 60 different fusion partners occur in a significant proportion of patients with AML and ALL (Daser and Rabbitts, 2005) Furthermore, an internal tandem duplication of MLL is one of...
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Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx
Ngày tải lên :
14/02/2014, 19:20
... Scientific Fund of the Ministry of Education, Science and Culture of Japan (G.T.); the Program for Promotion of Fundamental Studies in Health Sciences of the National Institute of Biomedical Innovation ... of miR-221 and miR-222 in PC12 cells, and that this induction is dependent on sustained activation of the ERK1 ⁄ pathway [20] Furthermore, the induction of miR-34a depends on the activation of ... Indeed, several examples of feedback regulation that involve miRNAs have been reported Below, we attempt to summarize our recent understanding of feedback regulation of signal cascades that involve...
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Tài liệu Báo cáo khoa học: Regulation of DNA fragmentation: the role of caspases and phosphorylation doc
Ngày tải lên :
14/02/2014, 22:20
... reduces the affinity of 14-3-3 for Bax and Bad and translocation of Bax and Bad to mitochondria independently of caspase activation [77,87] Phosphorylation of caspases Phosphorylation of caspases switches ... apoptotic signal on and off Caspase activation is under the direct control of kinases and phosphatases, and the indirect control of phosphorylation through the regulation of other apoptotic proteins ... activity of an isoform of PP1, PP1a [3] Similarly, activation of caspase-8 and -3 is regulated through their phosphorylation and dephosphorylation Phosphorylation of caspase-8 at Tyr397 and Tyr465...
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Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx
Ngày tải lên :
18/02/2014, 16:20
... cholesterol-enriched microdomains of the plasma membrane (caveolae), intracellular organelles, ligandindependent activation of growth factor- and cytokine receptors and autocrine stimulation of signal transduction ... metabolism and proliferation and provides cytoprotection, whereas cellular shrinkage leads to catabolism and insulin resistance and sensitizes cells to apoptotic stimuli The influence of cell volume ... activation of the p38-type MAPK and thereby inhibition of 5800 autophagic proteolysis [14] Thus, integrin-dependent cell volume sensing and signaling integrates into the overall context of insulin...
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