recently little was known about molecular structure of telomeres however during the last few years telomeres have been isolated and characterized from several sp

Tài liệu Báo cáo khoa học: NMR structure of AII in solution compared with the X-ray structure of AII bound to the mAb Fab131 pptx

Ngày tải lên : 20/02/2014, 23:20

... superimposed on the X-ray structure (dark blue colour) and (B) structure alignment of the fragment 4–7 of the 13 ensemble structures of AII to the fragment 3–6 of the X-ray structure of AII Residue ... 5B,b) The ﬁrst turn involves residues Asp1 and Arg2 and brings the N-terminus of the peptide in spatial proximity to the C-terminus of the peptide It was suggested that the stabilization of such ... family of the 48 structures, 13 structures were selected having the best allowed regions in the Ramachandran plot (Fig 4) The RMSD value of the ensemble of the 13 calculated structures, with respect...

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Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt

Ngày tải lên : 08/03/2014, 08:20

... angles of ()30°, 120°) and ()70°, 180°), respectively Secondary structure of the SP analogues [(R)-b2-HAla9 ]SP, [(S)-b3-HAla9 ]SP as well as [(R)-b2HPhe7 ]SP and [(R)-b2-HPhe8 ]SP have been synthesized ... regarding the differences in biological activities between [Ala9 ]SP and [Gly9 ]SP on the one hand, and [b2-HAla9 ]SP and [HGly9 ]SP on the other hand Indeed, the higher pharmacological potency of [b2-HAla9 ]SP ... domain of SP and [Aib9 ]SP The aN (i, i + 4) and ab (i, i + 3) NOEs were not detected in [b2-HAla9 ]SP, [b3HAla9 ]SP and [HGly9 ]SP, indicating more ﬂexible helical structures The C-terminal part of SP...

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Báo cáo khoa học: Common mode of DNA binding to cold shock domains Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus pot

Ngày tải lên : 23/03/2014, 09:21

... crystallography [15–18] and NMR spectroscopy [19,20], including Ec-CspA, Bs-CspB and the CSP from Bacillus caldolyticus (Bc-Csp) and Thermotoga maritima (Tm-Csp) The peptide chains of the CSP are arranged ... sequences with the highest degree of divergence from the proﬁle were added to the sequences of Bc-Csp and Bs-CspB and arranged for display in Fig 9B The level of conservation was calculated for ... single-strand binding to the cold shock domain chain shows great conformational ﬂexibility in the set of ligand-free CSP structures and interacts with the nucleobase group in the structure of Bs-CspBÆdT6...

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Chapter 2Communicating Over the Network Quangkien@gmail.com.OverviewDescribe the structure of a network, including the devices and media that are necessary for successful communications. Explain the function of protocols in network communications. Ex potx

Ngày tải lên : 01/04/2014, 12:20

... Strictly speaking, the suite is the definition of the protocols, and the stack is the software implementation of them 24 Network Protocols At the human level, some communication rules are formal and ... also TSPs Connect their customers to the Internet The Internet – ISPs connected to other ISPs 20 The Internet – A Network of Networks •Although there are benefits to using a LAN or WAN, most of ... – The amount of data and the speed at which it must be transmitted – The cost of the media and installation 17 Local Area Network (LAN) Local Area Network (LAN) An individual network usually spans...

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Báo cáo khoa học: "The last 10 years have witnessed considerable progress in molecular biology, trangenesis and genomics, and the assessment of wood and end-product properties" potx

Ngày tải lên : 08/08/2014, 14:21

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Báo cáo y học: " Molecular imaging of transcriptional regulation during inflammation" docx

Ngày tải lên : 11/08/2014, 03:20

... pathways have been described, the classical and the alternative pathway In inflammation, the classical NF-κB pathway is the more important of the two, and it is activated by a large number of stimuli, ... through the influence of cis-elements and chromatin structure [23] This is dependent on the location of insertion and a strategy to eliminate the problem is site specific insertion of the transgene ... and viral products, and stress-inducing stimuli such as γ-radiation, ultraviolet light and reactive oxygen species These stimuli induce the degradation of IκBα and the nuclear translocation of...

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Báo cáo y học: "Molecular imaging of transcriptional regulation during inflammationƠ" docx

Ngày tải lên : 11/08/2014, 06:22

... pathways have been described, the classical and the alternative pathway In inflammation, the classical NF-κB pathway is the more important of the two, and it is activated by a large number of stimuli, ... through the influence of cis-elements and chromatin structure [23] This is dependent on the location of insertion and a strategy to eliminate the problem is site specific insertion of the transgene ... and viral products, and stress-inducing stimuli such as γ-radiation, ultraviolet light and reactive oxygen species These stimuli induce the degradation of IκBα and the nuclear translocation of...

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As I Remember Recollections of American Society during the Nineteenth Century docx

Ngày tải lên : 16/03/2014, 01:20

... institution was patronized by many pupils from the South, and during my mother's time John C Calhoun was one of its students A few years ago a history of the school was published, and a copy of the book ... until three The principal of the school was the daughter of John Forbes, who for thirty years was the librarian of the New York Society Library He was a native of Aberdeen in Scotland, and was brought ... translation of the first two volumes of the Comte de Paris's "History of the Civil War in America." His devotion to my husband was pathetic, and I have frequently heard the Count say during the last years...

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Báo cáo khoa học: Recruitment of coregulator complexes to the b-globin gene locus by TFII-I and upstream stimulatory factor doc

Ngày tải lên : 23/03/2014, 07:20

... were subjected to several rounds of stringent washing The DNA was purified from the chromatin fragments and analyzed by realtime quantitative PCR using pairs of primers specific for the murine or human ... expression during erythroid differentiation of mouse ES cells RNA was isolated from ES cells incubated in the presence of EPO for or 12 days, as indicated The RNA was reverse transcribed and subjected ... differentiation of mouse ES cells RNA was isolated from the cells at the indicated time points after addition of EPO and subjected to quantitative RT-PCR analysis using primers specific for the bmajglobin...

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An Account of Some of the Principal Slave Insurrections, and Others, Which Have Occurred, or Been Attempted, in the United States and Elsewhere, During the Last Two Centuries. pptx

Ngày tải lên : 31/03/2014, 11:20

... It has been truly said that "the power of slavery lies in the ignorance, the degradation, the servility of the slaves, and of the non-slaveholding whites of the South, and of the corresponding ... negroes; they had killed about and wounded 12 more In their flight some of them shot themselves, others their wives, and then themselves; some absconded a few days, and then killed themselves ... before Such was the conduct of the negroes for the first nine months after their liberation, up to the middle of 1794 Of the conduct of the negroes during the year 1795, and part of 1796, I find...

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Báo cáo hóa học: " Assessment of Joystick control during the performance of powered wheelchair driving tasks" ppt

Ngày tải lên : 19/06/2014, 08:20

... participant Any specialized handle (e.g., ball) needed by the participant was transferred to the joystick used for the experiment The tablet PC was mounted at the rear of the wheelchair and another tablet ... single standard deviation of the vector scatter plotted on the joystick, while the v marks the value of the mean well to the mid-wheelchair All of the novice participants used the lowest speed, ... (Figure 3A), and joystick direction The number of joystick movements was defined as the number of times during a trial where the joystick excursion exceeded the threshold of 5% maximum displacement...

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Báo cáo hóa học: " Investigating the complexity of respiratory patterns during the laryngeal chemoreflex" pot

Ngày tải lên : 19/06/2014, 08:20

... represents the standard deviation of the original signal x(i) Results Our objective in this study was the investigation of changes in the complexity of the central respiratory network of the piglets during ... beginning of the inspiratory period [19] On the other hand, the pattern exhibited in the bottom plot highly resembles the one on the top plot, indicating systems' full recovery after the critical respiratory ... considered the first bursts visible on the EMGdia following the apnea and they are the outcome of the systems' efforts to restore normal activity The end of the LCR was considered when regular (eupneic)...

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báo cáo hóa học: " Control of interjoint coordination during the swing phase of normal gait at different speeds" ppt

Ngày tải lên : 19/06/2014, 10:20

... a landmark to separate the end of the swing phase from the beginning of the stance phase and the first data point following the cessation of force application on the force plate designated the ... The small angular offset between the first PC calculated from the torque range data and a vector extending through the mean of the same data set from the origin of the coordinate space (Figure 7) ... participants and speeds When analyzing the time series data, the input array consisted of data from all participants, all trials and from each of the three joints The resulting input data set (either...

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Báo cáo khoa học: "Foliation of spruce in the Giant Mts. and its coherence with growth and climate over the last 100 years" pdf

Ngày tải lên : 08/08/2014, 14:21

... of the foliation of spruce by means of the needle trace method], Dissertation Thesis, Univ Hamburg, 1997 [25] Sander C., Eckstein D., Reconstruction of the foliation of Picea abies by means of ... (SHED) of five spruces on their main axis, from Sander and Eckstein 1997, modified 161 Coherence of foliation of spruce with growth and climate Table II Correlation between foliation and growth ... cambium “suffers” from a loss of information and of mass transfer from the assimilative apparatus It should be mentioned that there was no indication of forest decline from the data obtained...

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Báo cáo y học: "A typology of practice narratives during the implementation of a preventive, community intervention trial" potx

Ngày tải lên : 11/08/2014, 05:21

... be gained from the subjective meanings of the CDOs (gathered via field diary and interviews) and the concepts they use to understand their practice [21]; much of the CDOs' practice (and program ... (from diary studies) as to the nature of 'respondent fatigue' [19] and whether diary entries and response rates decline over time A study of the effects of communal gardening on the health of ... and the ways in which these structures enables the narrator to make sense of and present their lives' [[14] p.89] It focuses attention on the interpretation of events rather than the events themselves...

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báo cáo khoa học: " A typology of practice narratives during the implementation of a preventive, community intervention trial" docx

Ngày tải lên : 11/08/2014, 16:20

... be gained from the subjective meanings of the CDOs (gathered via field diary and interviews) and the concepts they use to understand their practice [21]; much of the CDOs' practice (and program ... (from diary studies) as to the nature of 'respondent fatigue' [19] and whether diary entries and response rates decline over time A study of the effects of communal gardening on the health of ... and the ways in which these structures enables the narrator to make sense of and present their lives' [[14] p.89] It focuses attention on the interpretation of events rather than the events themselves...

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Báo cáo y học: "Characterization of viroplasm formation during the early stages of rotavirus infection" ppsx

Ngày tải lên : 12/08/2014, 02:20

... an increase in the number of viroplasms and in the amount of the NSP2 protein was observed The size of viroplasms was observed to increase when higher MOI’s were used There are several possibilities ... MOI’s of 0.1 and 0.5 respectively), there were more viroplasms per cell [1.6 and 3.1 for a MOI of 0.1 and 2.4 and 4.1 for an MOI of 0.5 (2 and hpi respectively)], while at an MOI of 10, when 87% of ... if the small viroplasms, presumably generated by the aggregation of NSP2 and NSP5 require an additional priming signal, or if it is only the concentration of free NSP2 and NSP5 what dictates the...

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Báo cáo y học: " Maternal smoking during pregnancy increases the risk of recurrent wheezing during the first years of life (BAMSE)" pot

Ngày tải lên : 12/08/2014, 16:20

... asthma and/ or respiratory Smoking 1during pregnancy and the first two years of the child Smoking during pregnancy and the first two years of the child and parents with or without asthma and/ or respiratory ... information i.e the number of cigarettes smoked both of mothers and fathers, was obtained in Q0 for the first two months, Q1 and Q2 for the first and second year of life, respectively In Q0 the parents ... years old 9.4 and 10%, respectively The corresponding reported postnatal exposure to paternal smoking was 16, 12 and 11%, respectively Any exposure to ETS during the first two years of life of...

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Báo cáo khoa học: "The key advance in the treatment of sepsis in the last 10 years … doing less" pot

Ngày tải lên : 12/08/2014, 23:22

... but at the expense of longer-term detriment [13] A greater understanding of both disease pathophysiology and iatrogenic harm will, I believe, lead to even better management, and thus further enhance ... continue to apply but must also develop still further The above advances have arisen from a realisation that overuse or misuse of drugs or devices, and/ or excessively striving for physiological ... AR, Young D, Black N, Rowan K: Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland Crit Care Med 2003, 31:2332-2338 Annane...

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Báo cáo y học: "Comment on and reply to "Analysis of variation of amplitudes in cell cycle gene expression" by Liu, Gaido and Wolfinger: On the analysis of gene expression during the normal, eukaryotic, cell cycle" docx

Ngày tải lên : 13/08/2014, 23:20

... data should speak for themselves 7) The DNA distribution of cells should be narrow in the synchronized cells and these distributions should then reflect the movement of cells through the division ... wishes to look at the response of genes to perturbation, then it is a good experiment The problem is whether the methods of Whitfield et al lead to an understanding of what happens in the normal, unperturbed ... on the variation in phase angle of the peak of expression If one had a particular cell growing with a 20 hour doubling time, and in some cells the peak was at hours, others 10 hours, and other...

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