... with the misuse of spectinomycin as reported by Ginns et al (1996) Although the high resistance rate of E coli chicken isolates to spectinomycin may be attributed to the misuse of this drug inthe ... for patientsin E coli-chicken ———————– Drugs Ampicillin, chloramphenicol Ampicillin, gentamicin Ampicillin, spectinomycin Ampicillin, tetracycline Ampicillin, TMPϩSMX Ampicillin, gentamicin, ... demonstrate alarmingly high individual and multiple resistance to antibiotics in E coli, reflecting the misuse of these agents inthe poultry industry Since chicken may act as a possible source of pathogenic...
... which the expression profile of each sample of interest is adjusted: this approach enables the investigator to compare the expression profile ofthe samples of interest with each other in terms of ... associated with Survivin levels indicates the increase in risk of death for 100 fold increase in Survivin expression (Table 3) Since only these four independent variables were retained by the ... Our findings are of particular relevance also from the tumor biology viewpoint because the Survivin gene encodes a key anti-apoptotic protein belonging to the inhibitor of apoptosis protein (IAP)...
... prognostic indicator in fulminant hepatitis inpatients without encephalopathy upon admission [10,11] Inthe present study, we examined 11 proinflammatory genes inpatients receiving therapy inthe ... linking downstream to the inflammatory process or to B cell receptor signaling NAMPT is another indicator for prognosis It is the rate-limiting component inthe mammalian nicotinamide adenine dinucleotide ... endothelial megakaryocytes expressing VWF Inthe signaling pathway, VWF interacts with integrins inthe extracellular matrix (ECM) and has functions inthe complement and coagulation cascades, linking...
... detected in an individual ofthe Uygur ethnic minority We did not find the 309-kb deletion of GJB6 in any ofthe 212 patients with monoallelic GJB2 coding region mutation or in any ofthe 105 ... covering 90% ofthe provinces in China; 3700 were patientsofthe Genetic Testing Center for Deafness, PLA General Hospital, during the period from March 2002 to December 2010 The majority ofthe ... 10.8%(767/7133) ofthe 7133 nonsyndromic hearing loss patients is postlingual and in 89.2% (6366/ 7133) is preligual The percent of postlingual hearing loss inthe 212 nonsyndromic hearing loss patients...
... Program staff inthe development phase facilitated the use ofthe training materials by the National Program inthe roll-out of TB/HIV training for HCWs involved in TB care inthe DRC soon after ... comparison of proportions of correct answers pre- and post training Post-training scores of clinic's HCWs were compared with the clinic's HIV testing acceptance rate by calculating the Pearson correlation ... development WD and FB also helped with developing the training AVR conceived ofthe study, participated in developing the training, coordinated the study with FB and helped to draft the manuscript All...
... Stage condition) at the time of ART initiation; (2) receipt of D4T inthe first-line regimen; or (3) receipt of nevirapine (NVP) inthe first-line regimen Inthe subset ofpatients where data ... Trends inthe clinical characteristics of HIV-infected patients initiating antiretroviral therapy in Kenya, Uganda and Tanzania between 2002 and 2009 Journal ofthe International AIDS Society ... to ART has also had a measureable impact on the economic and social dimensions of life in Africa by increasing labour capacity [4], maintaining educators [5], increasing survival of children [6]...
... denote the adjacency matrix of G Note that f : V (G) → {0, 1} is the characteristic function of a perfect dominating set if and only if (A + I)f = We are interested inperfect dominating sets of ... the family of all minimum dominating sets of Γ(Zn , U ) Note that since Γ(Zn , U ) is regular and 2n+1 2n+1 contains at least one perfect dominating set, a set S ⊆ V (G) is a minimum dominating ... case there are perfect dominating sets with defining number (See Remark 3) So far there is no nontrivial bound known for the defining numbers of minimum dominating sets of Γ(Zn , U ) We prove the...
... starting with the first month post initiation and continuing through the end ofthe year The mean cumulative days of hospitalization at the end of each ofthe 12 months post initiation indicated ... olanzapine and risperidone on the same day Importantly, the inclusion ofpatients who were continuously treated with the index drug during the year following initiation was aimed at avoiding the ... hospitalization following initiation on the index drug For inpatients at time of initiation on the drug, it was the first rehospitalization following discharge from the index hospitalization offset the higher...
... is notin accord with the results ofthe current study, since ERG findings were not significant It is also possible that one of them could be the result ofthe other Another important finding ... metabolic activity ofthe outer layers ofthe retina During the adaptation ofthe retina to dark, the amplitude ofthe EOG gradually decreases, reaching a nadir (dark trough) During the adaptation ... underlie them [31] The light peak is related mostly to the intensity ofthe stimuli, while the dark through does not Also, the light peak is related to the pre-adaptation level ofthe retina, while the...
... interest is the use of SLN biopsy inpatients undergoing neoadjuvant chemotherapy, because the number ofpatients choosing this option is increasing Until recently, feasibility and accuracy of ... surgery In this procedure, the skin flap covering the breast gland and the nipple-areola complex (NAC) are preserved In some cases the major ducts are removed Inthe past, the nipple has been routinely ... anticipated these findings as early as 1988, Page 11 of 17 and, through a joint effort of EORTC, the European Society of Mastology (EUSOMA) and Europa Donna, the innovative concept for standard guidelines...
... elements inthe supporting reticular tissue ofthe bursa and the supraspinatus tendon fibers reaching into the basal portion ofthe organ, in addition to the dense connective tissue between the bursa ... supraspinatus insertion site [21] These reports are not only in line with our findings, but also strongly suggest significant influence of molecular events within the subacromial bursa on the fate ofthe ... staining for AP Note the co-distribution of AP, both the bursa-derived intrinsic enzyme and the C2C12-derived enzyme, with the BMP deposits within the tissue supporting egg maturation [27,28], the...
... amino acid insert and the KTS insert inthe zinc finger region, did not influence GP210 expression in SAOS osterosarcoma cells, in a system using tetracycline-induced repression of expression In ... either of these proteins The 121-kDa pore membrane protein POM121 [7,8] is located inthe pore membrane domain ofthe NPC with a short (29 residues) N-terminal tail protruding into the lumen of ... other isoforms of WT1 regulate GP210 Figure WT1 isoform A does not regulate expression of GP210 WT1 isoform A does not regulate expression of GP210 SAOS cells conditionally expressing WT1 isoform...
... the genotyping, participated inthe selection of SNPs, analysis, and prepared the manuscript; PR and SS participated inthe genotyping; AP coordinated thepatients' accrual and updated the clinicopathological ... participated inthe analysis and interpretation ofthe results obtained with the in- silico methods; MB participated inthe design and discussions; IO conceived and coordinated the study, participated in ... 0.0294) [7] In another study, investigators have found strong expression (> 40% cells stained) of MMP2 in 78% ofthe invasive melanomas [8] At the genetic level, two functional promoter single nucleotide...
... higher in young males compared in females [7] One ofthe interesting findings ofthe current study is the observation of high positivity rate of anti-HDV ELISA that is 88.8% in HBV positive patients ... findings (about 30%) The results of this study further suggest that the prevalence of HBV/HDV co-infection in Pakistan has increased during the last decade On the other hand an overall decline ... HBV infection [9,12,14,15] Even in India that is our neighbor inthe East, a decline in HDV infection has been seen in recent years [14] The same tendency in HDV decline has also been observed in...
... changes inthe airway The first step of assessing the potential importance of these cells inthe inflammatory process would be to assess their numbers and function within the airways Therefore, in ... Glucocorticosteroids The Nottingham Local Research Ethics Committee approved the study protocol and written informed consent was obtained from the 26 subjects before entering the blinded study Of these, the 11 ... perforin content [19], has not been previously reported in induced sputum and it is possible to hypothesise that these cells are causing some ofthe damage seen inthe COPD airways Furthermore,...
... group The mean duration of symptoms inthe FM group was 13.65 ± 9.19 years The mean tender points inthe FM group were 14.9 ± 3.1 points The most prominent features of these FM patients were pain ... hypothesis, showing the presence of mitophagy in BMCs of FM patients Autophagy is a regulated lysosomal pathway involved inthe degradation and recycling of cytoplasmic materials [3842] During ... fluorescence, indicating a reduction in lysosomal activity after CoQ10 treatment In addition, we analyzed the expression of genes involved in autophagic processes, such as BECLIN and MAP-LC3...
... participated inthe recruitment and clinical evaluations ofpatients LS participated inthe recruitment ofpatients and clinical data analysis MC participated inthe design and coordination ofthe study ... existence of important alterations inthe phenotype of peripheral B cells from RA patients, involving the expression ofthe co-stimulatory molecule CD86 and the inhibitory receptor FcgRIIb, the latter ... together with a blockage of FcgRIIb is sufficient to induce an increase inthe expression of CD86 [38,39], whereas the overexpression of this receptor on murine B cells reverses the induction of...
... (recorded in 36% of patients) , followed by soft tissue infection (17%), intra-abdominal infection (12%), urinary tract infection (11%) and others (11%); sepsis of undetermined source was recorded in ... conditions and the type of individual biological response, the latter being determined from clinical findings such as vital signs and GCS score The use of ANNs inthe setting of sepsis has not been ... hidden layer and two inthe output layer, the latter indicating death versus survival Ofthe cohort 75% was used to train the network and 25% was used in testing The training criterion was that...
... significant risk of unnecessary suffering; the action of others is needed to prevent this suffering; the action of others has a high probability of preventing it; and the benefit that the patient ... is therefore relevant to the decision to disclose because doing so may ultimately serve thepatients interests in avoiding needless suffering [5] In general, disclosure is justified when: the ... disclose the patient’s underlying health condition risks minimizing opportunities for the timely withdrawal of painful or futile interventions The physicians’ obligation of beneficence to their patients...
... common in HIV-2 than in HIV-1 infection Still, little is known about the role of humoral immunity inthe evolution ofthe HIV-2 env gene Inthe present study we analyze, for the first time, the ... is the main driver ofthe rapid intra-host evolution ofthe C2 and C3 regions in HIV-2 [15,25,58,60,64-66] Indeed, we found that most ofthe amino acids under selection are located in C2, including ... below), inthe envelope complex of HIV-2 differs substantially from that of HIV-1 Glycans on HIV-1 envelope protein play an important role inthe folding ofthe glycoproteins, in infection and in...