quality of life in alzheimer s disease scale
báo cáo hóa học: " Utility of WHOQOL-BREF in measuring quality of life in Sickle Cell Disease" docx
Ngày tải lên :
18/06/2014, 19:20
... WHOQOL score Discussion The main purpose of this paper was to assess the utility of this instrument in patients with SCD living in Jamaica In all of its performance measures, the WHOQOL-Bref has Page ... role limitations and total scores, but less correlated (r ≤ 0.30) with SF-mental health scores as this subscale assesses the physical state of patient 's quality of life We expect a smaller correlation ... generic instruments will allow further study of their possible weaknesses and strengths Therefore, the specific aims of this study are to: i) assess the properties of WHOQOL-BREF in SCD; and...
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báo cáo hóa học:" Utility of WHOQOL-BREF in measuring quality of life in Sickle Cell Disease" doc
Ngày tải lên :
20/06/2014, 16:20
... WHOQOL score Discussion The main purpose of this paper was to assess the utility of this instrument in patients with SCD living in Jamaica In all of its performance measures, the WHOQOL-Bref has Page ... role limitations and total scores, but less correlated (r ≤ 0.30) with SF-mental health scores as this subscale assesses the physical state of patient 's quality of life We expect a smaller correlation ... generic instruments will allow further study of their possible weaknesses and strengths Therefore, the specific aims of this study are to: i) assess the properties of WHOQOL-BREF in SCD; and...
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báo cáo hóa học:" Health-Related Quality of Life in Parkinson disease: Correlation between Health Utilities Index III and Unified Parkinson’s Disease Rating Scale (UPDRS) in U.S. male veterans" docx
Ngày tải lên :
20/06/2014, 16:20
... Kleiner-Fisman et al Health and Quality of Life Outcomes 2010, 8:91 http://www.hqlo.com/content/8/1/91 The Unified Parkinson Disease Rating Scale (UPDRS) consists of assessments in domains including, ... healthrelated quality of life across different disease states While questionnaires for evaluation of HRQoL in PD (such as the PD-39 and Parkinson s Disease Quality of Life instruments [13] have ... quality of life in PD using a “health utilities index” approach, and to assess the relationship between health utility scores and PD severity as measured using standard disease- specific tools...
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báo cáo hóa học: " Measuring health-related quality of life in Hungarian children with heart disease: psychometric properties of the Hungarian version of the Pediatric Quality of Life Inventory™ 4.0 Generic Core Scales and the Cardiac Module" pptx
Ngày tải lên :
18/06/2014, 19:20
... disease report significantly impaired psychosocial quality of life irrespective of the severity of heart disease [23] This recent result affirms previous findings of studies focusing on various ... of the scales, and all scales exceeded the satisfactory level of internal consistency reliability of at least 0.40 Construct validity Assessing the construct validity of the questionnaires, statistically ... [9,42] In addition to the single scale scores there is the possibility to calculate summary scores: the Physical Health Summary Score is the same as the Physical Functioning Subscale, whereas to...
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Tài liệu Báo cáo khoa học: Animal models of amyloid-b-related pathologies in Alzheimer’s disease docx
Ngày tải lên :
16/02/2014, 09:20
... pathogenesis Therapeutic studies in AD models Access to good animal models is crucial to success in developing disease- modifying therapeutics However, AD neuropathology is incomplete in the Ab-expressing ... cross-breeding experiments is strengthened if expression and deletion of the gene (s) results in the opposite outcome, or if the results are substantiated by in vitro studies or analyses of clinical samples ... by crossing PDGF–a-synuclein and APP-SweInd, which led to a 1.6-fold increase in a-synuclein inclusions in comparison with transgenic mice that expressed only wild-type human a-synuclein Similar...
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Báo cáo khoa học: Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer’s disease brain doc
Ngày tải lên :
16/03/2014, 22:20
... either polyglutamine or polyalanine expansions in Huntington disease, Huntington related diseases, and various forms of a-synuclein associated with Parkinson disease and synucleinopathies [27] Taken ... phosphorylate eEF2 in its N-terminus (Thr56) that subsequently blocks eEF2 binding to ribosomes, resulting in decreased rates of protein synthesis Dephosphorylation of eEF2 relieves its translational ... Foundation, SADF (Insamlingsstiftelsen for ¨ Alzheimer- och Demensforskning), Socialstyrelsens Stiftelser, Stiftelsen for Alderssjukdomar, and Svenska ¨ ˚ Lakaresallskapet ¨ ¨ FEBS Journal 272...
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The welfare state as a determinant of women’s health: support for women’s quality of life in Canada and four comparison nations pptx
Ngày tải lên :
22/03/2014, 11:20
... activities are the responsibility of the National Institute of Public Health The six main strategies outlined are as follows: • Increase social capital in the Swedish society: This includes efforts ... decisions that support women in their lives [98] This is the meaning of equity and fairness In terms of contemporary analyses of women s quality of life, these policy changes in Canada—and elsewhere—have ... private assistance through local authorities A government system provides “Cash Benefits for Closely Related Persons” through the special assistance system for a maximum 60 days in case of serious illness...
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báo cáo hóa học: " Measuring disease-specific quality of life in rare populations: a practical approach to cross-cultural translation" potx
Ngày tải lên :
18/06/2014, 19:20
... outlining guidelines for a comprehensive process of cross-cultural adaptation[2,3] These guidelines and recommendations require the inclusion of large numbers of subjects across several countries ... fieldtesting Expert committee consists of methodologists, health care professionals, language experts and translators Inclusion of bilingual members is ideal Testing with participants The translated ... naïve translators NSE.# Professional translators NSE Professional, naïve translators NSE Translate independently Health Assessment Lab compared back translations to initial version for "conceptual...
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báo cáo hóa học: " Reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in dyspepsia: A six-country study" pptx
Ngày tải lên :
18/06/2014, 22:20
... (including history of gastrointestinal diseases) and frequency of dyspepsia symptoms (number of days with episodes during the last days) Investigators also assessed the severity of patients' dyspepsia ... Patient-based assessment in dyspepsia: development and validation of Dyspepsia Symptom Severity Index (DSSI) Dig Dis Sci 2000, 45:1172-1179 Lohr K: Assessing health status and quality- of- life instruments: ... validation of translation to Spanish of the gastrointestinal symptoms rating scale (GSRS) and quality of life in reflux and dyspepsia (QOLRAD) in patients with gastroesophageal reflux disease] Revista...
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Báo cáo hóa học: " Associations between disease severity, coping and dimensions of health-related quality of life in patients admitted for elective coronary angiography – a cross sectional study" pdf
Ngày tải lên :
18/06/2014, 22:20
... respectively Functional status Self-reported functional status was assessed by the Exertional Capacity Scale (ECS) consisting of nine items measuring physical function, a subscale of the disease ... Statistical analysis In computing scale scores, missing substitution by the means of non missing items in the subscale was performed in accordance with the manual and as suggested Page of 12 (page ... dissatisfied?" It contains seven alternative responses: 1) Very satisfied; 2) Fairly satisfied; 3) Satisfied; 4) So-so; 5) Dissatisfied; 6) Fairly dissatisfied; 7) Very dissatisfied [37] Statistical...
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báo cáo hóa học: " Using animal models to determine the significance of complement activation in Alzheimer''''s disease" pptx
Ngày tải lên :
19/06/2014, 22:20
... models of human disease generally have similar pathological findings to the human disorders, distinct differences remain These models may be appropriate for studying some aspects of a disease process, ... and proteins in the Alzheimer' s disease brain Brain Res Mol Brain Res 2000, 81:7-18 Janus C, Phinney AL, Chishti MA, Westaway D: New developments in animal models of Alzheimer' s disease Curr Neurol ... celecoxib in the treatment of progression of Alzheimer' s disease [abstract] Sixth International Stockholm/Springfield Symposium on Advances in Alzheimer Therapy 2000:180 Van Gool WA, Weinstein HC, Scheltens...
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báo cáo hóa học: " Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer''''s disease" pdf
Ngày tải lên :
19/06/2014, 22:20
... characteristics of the cases used in this study Shown are differences between groups of the cases used in this study [PMI post-mortem interval, SD standard deviation] Braak score for neurofibrillary ... Increased neuronal COX-2 expression leads to increased expression of cell cycle mediators in post mitotic neurons, as shown using a transgenic mouse model with increased neuronal COX-2 expression ... 25 26 Pasinetti GM, Aisen PS: Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer' s disease brain Neuroscience 1998, 87:319-324 Combrinck M, Williams J, De Berardinis MA, Warden...
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báo cáo hóa học: " The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer''''s disease" ppt
Ngày tải lên :
19/06/2014, 22:20
... tyrosine kinases or inhibition of phosphatidylinositol-3 kinase (PI3K) attenuates ROS production These findings suggest that these kinases are involved in upstream signaling cascades responsible ... engagement of an ensemble of cell surface receptors initiates a tyrosine kinase-based signaling cascade Tyrosine phosphorylation of the Vav-GEF results in the activation of downstream Rac1 GTPase Recently, ... functional events in Alzheimer' s disease J Alzheimers Dis 2004, 6:171-175 Markesbery WR: Oxidative stress hypothesis in Alzheimer' s disease Free Radic Biol Med 1997, 23:134-147 Shimohama S, Tanino H,...
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báo cáo hóa học:" Quality of life in patients with various Barrett''''s esophagus associated health states" ppt
Ngày tải lên :
20/06/2014, 15:20
... estimates to be used in cost-effectiveness analyses as well as guidance for designing larger Barrett 's esophagus quality of life assessment studies Our findings may also provide some preliminary ... misses unsuspected cancer in Barrett 's esophagus with high-grade dysplasia Gastrointest Endosc 1999, 49(2):170-176 Stein HJ: Esophageal cancer: screening and surveillance Results of a consensus ... refinements that resulted from this 'pre-testing' were further simplifications of many of the medical terms used to describe the various health states Data analysis This was a descriptive, cross-sectional...
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báo cáo hóa học:" Double disadvantage: a case control study on health-related quality of life in children with sickle cell disease" potx
Ngày tải lên :
20/06/2014, 15:20
... with sickle cell disease: mediation of pain by internalizing symptoms and parenting stress Health Qual Life Outcomes 2008, 6:60 28 Eiser C, Morse R: Quality- of- life measures in chronic diseases of ... domain, compared to healthy siblings This finding is congruent with results of a previous study in our hospital [13] as well as other studies on adjustment in adolescents with SCD [29,30], and seems ... adolescents aged between and 18 years The KIDSCREEN-52 consists of 52 items assessing ten domains of HRQoL during the previous week: ‘Physical Well-being’, ‘Psychological Well-being’, ‘Moods &...
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báo cáo hóa học:" Measuring health-related quality of life in children with cancer living in mainland China: feasibility, reliability and validity of the Chinese mandarin version of PedsQL 4.0 Generic Core Scales and 3.0 Cancer Module" pdf
Ngày tải lên :
20/06/2014, 15:20
... Further studies should focus on testing responsiveness of the Chinese mandarin version scales in longitudinal studies and in other areas, particularly in rural areas Studies measuring HRQOL in children ... all scales On this module, 40.7% of the items across all forms had no missing responses The highest percentage of missing responses for any single item on the Caner Module was 3.2% for Child self-report ... unanswered was calculated for each subject on each single and summary scale and averaged over subjects [29] The presence of floor and ceiling effects was assessed for the subscales scores and summary...
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báo cáo hóa học:" Measuring disease-specific quality of life in rare populations: a practical approach to cross-cultural translation" docx
Ngày tải lên :
20/06/2014, 16:20
... outlining guidelines for a comprehensive process of cross-cultural adaptation[2,3] These guidelines and recommendations require the inclusion of large numbers of subjects across several countries ... fieldtesting Expert committee consists of methodologists, health care professionals, language experts and translators Inclusion of bilingual members is ideal Testing with participants The translated ... naïve translators NSE.# Professional translators NSE Professional, naïve translators NSE Translate independently Health Assessment Lab compared back translations to initial version for "conceptual...
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báo cáo hóa học:" Psychometric validation of the Dutch translation of the quality of life in reflux and dyspepsia (QOLRAD) questionnaire in patients with gastroesophageal reflux disease" ppt
Ngày tải lên :
20/06/2014, 16:20
... presence of reflux esophagitis grade C or D, presence or history of other gastrointestinal diseases and conditions, and presence or history of other non-gastrointestinal serious diseases and conditions ... Italian translation of the gastrointestinal symptom-rating scale and quality of life in reflux and dyspepsia questionnaire in patients with gastro-oesophageal reflux disease Clin Drug Invest 2004, ... Carlsson J, Wiklund I: [Psychometric validation of translation to Spanish of the gastrointestinal symptoms rating scale (GSRS) and quality of life in reflux and dyspepsia (QOLRAD) in patients with...
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báo cáo hóa học:"Decreased health-related quality of life in disease-free survivors of differentiated thyroid cancer in Korea" potx
Ngày tải lên :
20/06/2014, 16:20
... functioning domain (Table 3) HADS-A, HADS-D, and BFI scores for the disease- free survivors of DTC and the control group are shown in Table Disease- free survivors of DTC had greater levels of distress ... previous reports and future study using questionnaire assessing HRQOL in general population is needed Lastly, this study was cross-sectional design, which can limit the generalizability of our findings ... 29 Hirsch D, Ginat M, Levy S, Benbassat C, Weinstein R, Tsvetov G, Singer J, Shraga-Slutzky I, Grozinski-Glasberg S, Mansiterski Y, Shimon I, Reicher-Atir R: Illness perception in patients with...
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báo cáo khoa học:" Decreased health-related quality of life in disease-free survivors of differentiated thyroid cancer in Korea" pptx
Ngày tải lên :
12/08/2014, 01:21
... functioning domain (Table 3) HADS-A, HADS-D, and BFI scores for the disease- free survivors of DTC and the control group are shown in Table Disease- free survivors of DTC had greater levels of distress ... previous reports and future study using questionnaire assessing HRQOL in general population is needed Lastly, this study was cross-sectional design, which can limit the generalizability of our findings ... 29 Hirsch D, Ginat M, Levy S, Benbassat C, Weinstein R, Tsvetov G, Singer J, Shraga-Slutzky I, Grozinski-Glasberg S, Mansiterski Y, Shimon I, Reicher-Atir R: Illness perception in patients with...
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