qsars for human health endpoints
Predicting Chemical Toxicity and Fate - Section 3 ppt
Ngày tải lên :
11/08/2014, 12:21
... three endpoints are quite different in terms of relevance for the human health, and in terms of suitability for modeling The yes/no response is highly relevant and predictive for the human health ... into QSARs for binding and chemical reactivity (Lewis et al., 2002b) Lewis et al (2001) presented QSARs for the free energies of binding of substrates to human CYP isoforms and P450 isoform induction ... experts based on a database of previous information, for example, on different endpoints in toxicity All the information is stored in the software’s rule base for later recall The rules describe toxicophores/pharmacophores...
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Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"
Ngày tải lên :
25/10/2012, 10:45
... gold-standard for clinical effectiveness, we abstracted additional data from the medical records using a structured case report form developed to descriptively inform the reason for discordance ... medications Methods We linked Veterans Health Administration medical and pharmacy claims for RA patients participating in the longitudinal VA RA registry (VARA) For individuals initiating a new biologic ... administrative claims data To test the performance of the effectiveness algorithm and to see whether it was similar for non-biologic RA treatments, we performed a separate analysis of RA patients...
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Comparison of Methods for the Extraction of Bioflocculants from Activated Sludge
Ngày tải lên :
05/09/2013, 09:08
... measured for min, and the relative A660 against the control test was calculated every minute using the following formula: The relative A660 = A660 of flocculating test A660 of control test For the ... effective extraction method for activated sludge However, cell disruption is not effective for the isolation of bioflocculants Thus, NaOH extraction was the most effective method for the extraction of ... analysis SDS slab-polyacrylamide gel electrophoresis (SDS-PAGE) was performed using the method of Laemmli (1970) A separating gel was formed with 12.5% acrylamide and 0.1% SDS, with a 2.5% acrylamide...
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Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders ppt
Ngày tải lên :
23/03/2014, 23:20
... Enforcement and Corrections Standards and Testing Program is an applied research effort that determines the technological needs of justice system agencies, sets minimum performance standards for ... Isopropyl chloroformate Isopropyl isocyanate n-Butyl chloroformate n-Butyl isocyanate Nitric oxide n-Propyl chloroformate Parathion Perchloromethyl mercaptan sec-Butyl chloroformate tert-Butyl ... cause 14 d) period could cause form Dried agent is infection of force infection of force very stable; stable in deploying biological deploying biological aerosol form agent agent 17 Fever and...
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Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders pdf
Ngày tải lên :
23/03/2014, 23:20
... Enforcement and Corrections Standards and Testing Program is an applied research effort that determines the technological needs of justice system agencies, sets minimum performance standards for ... Technology, which develops voluntary national performance standards for compliance testing to ensure that individual items of equipment are suitable for use by criminal justice agencies The standards ... Equipment Performance Reports designed to help justice system procurement officials make informed purchasing decisions Publications are available at no charge through the National Law Enforcement...
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nmr methods for the investigation of structure and transport
Ngày tải lên :
29/05/2014, 18:32
... standard watershed transformation For the quantitative analysis of the uniformity of mixtures, the influence of artifacts on the signal variance is calculated Finally, a method for automatic nonlinear ... for the discrete inverse Fourier transform then reads Qn D N X C M k expŒi k N 1/.n 1/=N ; Ä n Ä N: (2.40) kD1 For multidimensional data the procedure (2.40) has to be applied sequentially for ... experimentally chosen B.r; t/ For a real-valued phase as in (2.38) the integral transform is a Fourier transform Relaxation corresponds to an imaginary phase and a Laplace transform Even a coarse resolution...
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báo cáo hóa học: " The evolution of methods for the capture of human movement leading to markerless motion capture for biomechanical applications" pptx
Ngày tải lên :
19/06/2014, 10:20
... related to the mechanics of human movement The work at the University of California formed the basis for many of the fundamental techniques currently used for the study of human locomotion More recently, ... of a human body with either fewer joints or reduced number of degrees of freedom are often utilized for enhancing computational performance For instance, existing methods for gait-based human ... the potential for markerless human motion capture for biomechanical and clinical applications One of the challenges for a markerless system is the acquisition and representation of human movement...
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báo cáo hóa học:" Biomechanical testing of a polymer-based biomaterial for the restoration of spinal stability after nucleotomy" pptx
Ngày tải lên :
20/06/2014, 04:20
... problems in order to be beneficial for the patient In spinal surgery, preventive procedures to avoid common follow-up complications are conceivable in operations for disc herniation with predominant ... complain about back pain with the same intensity or worse than shortly before operation [4] In the literature, three major causes for the development of pain are suggested: (1) segmental spinal instabilities ... Units Preparation was performed according to the same standard microsurgery procedure used in our neurosurgical department In brief, the spinal canal was exposed by performing a minimal interlaminar...
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Báo cáo hóa học: " A quantum dots and superparamagnetic nanoparticle-based method for the detection of HPV DNA" ppt
Ngày tải lên :
21/06/2014, 01:20
... Page of predenatured at 95°C for 10 min, then 55°C for 30 The particles coupled with streptavidin were added into the hybridization mixtures and incubated at 37°C for 10 and enriched in the bottom ... wave invader human papillomavirus (HPV) assay and the digene HPV hybrid capture assay for detection of high-risk HPV DNA J Clin Microbiol 2008, 46:1641-1646 Denny LA, Wright TC Jr: Human papillomavirus ... collected from outpatients at our department, and the written informed consent was obtained Ten HPV-16-negative and ten HPV-16-positive human DNA samples were kept in the clinical laboratory of our...
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Cocoa Processing Methods for the Production of High Quality Cocoa in Vietnam ppt
Ngày tải lên :
21/06/2014, 06:20
... 12: Partitioned boxes for fermentation of quantities above 100kg wet beans 13: Drainage holes, for excess moisture, in bottom of boxes 14: Cocoa beans spread on wire mesh, for two hours, prior ... Tre Province is thanked for their assistance in farmer surveys and the selection of smallholder sites for solar drier evaluation Smilja Lambert of Mars, Inc is thanked for her assistance with ... rapid rise in temperature for cocoa pods that have been stored for seven days The faster fermentation and temperature rise results in an improved quality cocoa Therefore pod storage times of...
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Standard Methods for the Examination of Water and Wastewater P4. end
Ngày tải lên :
29/07/2014, 18:58
... indicator for problems is the bubble pattern; visually inspect the system for any abnormal bubble pattern that may indicate problems with flow For each analysis, check individual method for compounds ... solution then can be introduced into the ion chromatograph for separation This method is usable but not recommended for fluoride Acetate, formate, and carbonate interfere in determining fluoride ... are about 0.1 mg/L for the anions with an © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for the Examination...
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Standard Methods for the Examination of Water and Wastewater P3
Ngày tải lên :
29/07/2014, 18:58
... Eudorina Green Algae and Associated Forms 77a Cells jointed together to form a net Hydrodictyon 77b Cells not forming a net 78a Cells attached side by side to form a plate or ribbon one Scenedesmus ... ed Revised by D.W Phillips Stanford Univ Press, Stanford, Calif DAILEY, M.D., D.J REISH & J.W ANDERSON, eds 1994 Ecology of the Southern California Bight Univ California Press, Berkeley REISH, ... Algae in Water Supplies U.S Pub Health Serv Publ No 657, Washington, D.C ABBOTT, I.A & G.J HOLLENBERG 1976 Marine Algae of California Stanford Univ Press, Stanford, Calif EDWARDS, P 1976 Illustrated...
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Standard Methods for the Examination of Water and Wastewater P2
Ngày tải lên :
29/07/2014, 18:58
... for the Examination of Water and Wastewater Anacystis © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for ... Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for the Examination of Water and Wastewater Synedra © Copyright 1999 by American Public Health ... Methods for the Examination of Water and Wastewater Ceratium © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for...
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Standard Methods for the Examination of Water and Wastewater P1
Ngày tải lên :
29/07/2014, 18:58
... Methods for the Examination of Water and Wastewater © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for the ... catalogs, membership benefits, or other information, please contact each organization directly: American Public Health Association (APHA) American Public Health Association (APHA), founded in 1872, ... public health professionals in the world, representing more than 50,000 members from 77 public health occupations The mission of APHA is to protect and promote personal and environmental health...
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Báo cáo khoa học: "Comparison of Diagnostic Methods for the Detection of Parasites in Fish" pdf
Ngày tải lên :
06/08/2014, 19:20
... added PCR was performed in the PCR machine (Gene Amp PCR system 9700) with an initial 95oC step for minutes and 30 cycles of denaturation at 94oC for 30 seconds, annealing at 55oC for 30 seconds ... microscope Stretching of these metacercariae was done by hot formalin for two minutes Then, they were kept in Eppendorf tubes with neutral formalin (4%) Diagnosis of parasitic infections * Diagnosis ... placed in separate vials with PBS For later study, all of the parasites were kept in Eppendorf tubes with ethanol (70%) or neutral formalin (4%) The digestion method For larger fish, different parts...
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Báo cáo khoa học: " Effective methods for the production of immunoglobulin Y using immunogens of Bordetella bronchiseptica , Pasteurella multocida and Actinobacillus pleuropneumoniae" docx
Ngày tải lên :
07/08/2014, 15:20
... (Bahedelin Co., Germany) for 30 seconds After centrifugation of the sonicated bacterial culture broth at 8,000 rpm for 30 min, the supernatant was centrifuged at 20,000 rpm for hr at 40C and the ... broth (TSB) (Difco Co., Detroit, MI, USA) at 37℃ for 18 hrs with shaking After incubation, the bacteria were harvested by centrifugation at 8,000 rpm for 30 min, washed with phosphate buffered saline ... P multocida D:4 as the causative agents of AR, P multocida A:3 for pneumonic pasteurellosis and A pleuropneumoniae serotypes and for porcine contagious pleuropneumonia These bacterial strains...
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Báo cáo khoa học: " Comparison of two sap flow methods for the estimation of tree transpiration" ppt
Ngày tải lên :
08/08/2014, 23:22
... differences was about 4.5 % for trees and No physical explanation could account for these differences measurement times more CONCLUSION This showed an accuracy of greater than 10 % for the two methods, ... required for an accurate estimation of transpiration The combination of the two methods seems possible in the same experiment The heat balance for the small trunks, and transpiration calculation for ... brute dans le tronc des arbres, Ann Sci For 42 (1985) 81-88 [5] Granier A., Huc R., Barigah S.T., of natural rain forest and its depenclimatic factors, Agric For Meteorol 78 19-29 Transpiration dence...
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Báo cáo sinh học: "Use of sib-pair linkage methods for the estimation of the genetic variance at a quantitative trait locus" pps
Ngày tải lên :
09/08/2014, 18:21
... nature must be known for an exact determination Therefore, it was decided that a replication was significant for Method I if both null hypotheses were rejected at a 5% level For the interpretation ... estimated values for given in table III for the methods For low values of an overestimation occurs, which is caused by the fact that a certain number of replications could not be calculated for reasons ... fully informative matings is an appropriate way to improve the power of QTL-detection for a given number of genotypings If many markers are to be examined, the parents will only be informative for...
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Báo cáo y học: "An alternative methodology for the prediction of adherence to anti HIV treatment" ppt
Ngày tải lên :
10/08/2014, 05:21
... Planck-Institut für Informatik (Max-Planck-Institute for Informatics, Saarbrücken, Germany), Központi Fizikai Kutató Intézet – Részecske-és Magfizikai Kutatóintézet (Central Research Institute for Physics ... Volmink J: A review of health behaviour theories: how useful are these for developing interventions to promote long-term medication adherence for TB and HIV/AIDS? BMC Public Health 2007, 7(147):104-119 ... physicians must have accurate and reliable information on the effectiveness and efficacy of the prescribed treatment regime To meet the need for having objective information on adherence, a method is...
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báo cáo khoa học: " Social networks, work and network-based resources for the management of long-term conditions: a framework and study protocol for developing self-care support" potx
Ngày tải lên :
10/08/2014, 10:23
... CLAHRC for Greater Manchester Author details Health Sciences Research Group, and Collaboration for Leadership in Applied Health Research and Care (CLAHRC) for Greater Manchester, School for Community ... tax-payers) Personal communities health related and health relevant functions Voluntary and community groups with with health related and health relevant functions Non -health professionals Self management ... nonhealth professionals, and, to a more limited extent, health professionals The distribution of the responsibilities for LTCM between groups of involved actors outside of the immediacy of the health...
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