... stenographer The company team was scheduled to play another team on the Georgetown University campus the evening of June 24, 1903 When they arrived, theother team failed to show, so they decided to split ... When one ofthe fielders attempted to throw tothe other, the ball struck Dodson on the left side of his neck He collapsed and attempts to revive him failed An autopsy concluded that he died of a ... beaning.157 Other Pitched-Ball Fatalities While beanings were the most frequent cause of player fatalities prior tothe adoption ofthe batting helmet, pitched balls striking other parts ofthe anatomy...
... man.’ Andtheking said, ‘This is your mother.’ Then they kissed him and took him into the palace Sothe star child became king He gave bread and clothes tothe poor, and was kind and good to everyone ... star child and took him through the house andthe garden and up the five steps tothe door Then he sent him into the street The star child went out ofthe gate ofthe city and came tothe forest ... cried the witches, when they saw her She laughed and ran tothe tree and took the fisherman’s hand She pulled him out into the moonlight and began to dance with him Theother witches began to dance...
... during the assembly ofthe bc1 complex is also unknown Furthermore, as in the case ofthe biogenesis ofother multi-subunit complexes ofthe mitochondrial respiratory chain, the assistance of specific ... is too small to explain the dimerization ofthe bc1 complex at this stage (i.e just after the addition of ISP and Qcr10p) 1910 On theother hand, in the transition from the 500 kDa band tothe ... demonstrated, the incorporation of all theother subunits into the bc1 core structure proceeds normally, thus leading tothe formation ofthe bc1-oxidase supercomplexes [12] On theother hand, Qcr9p,...
... Also, the effect ofthe siRNA was also measured against time following transfection andthe results indicated thatthe effect of VBARP siRNA was also time dependent (data not shown) Taken together, ... distribution of VBARP is independent ofthe cycling stage ofthe cells Identification of biological function(s) of VBARP using a siRNA assay To examine the role of endogenous VBARP in the regulation of ... CK2), andthe presence of nine potential myristoylation sites in the VBARP protein (Fig 2C) psort software predicted with high accuracy the subcellular localization of VBARP, and indicated that...
... to cell The subcellular locations of these proteins also vary, with some being present in the ER, others in the nuclear membrane and some present at both these locations Thus the relocation of ... and appears tobe cell specific In the majority of studies, cPLA2-a has been reported to translocate tothe nuclear periphery and structures within the cytosol, sites presumed tobethe nuclear ... disease states and in response to inflammatory and mitogenic stimuli [11,12] Both isoforms have been shown to localize at the nuclear envelope and in the endoplasmic reticulum (ER) of endothelial cells...
... August, The Four Musicians of Bremen; in early September, Jack andthe Beanstalk; and in early October, Goldie Locks andthe Three Bears Meanwhile, that September, he contracted another company, the ... borrowing the name of Kansas City’s famed Newman Theatre, to sell the owner ofthe theater on buying it and making it a regular feature Walt arranged to show the 300-foot cartoon to Milton Feld, the ... Arts and Sciences; the Archives of Performing Arts andthe Regional History Collections at the University of Southern California; the Los Angeles Times Photographic Archive ofthe University of...
... we found the radiolabeled oxygen at the Ca and Cb positions in a comparison ofthe mass spectrum with thatofthe products ofthe reaction with GG and unlabeled water The incorporation of 18O from ... affects the formation ofthe quinonemethide Then, water attacks the Ca position in the quinonemethide andthe b-aryl ether linkage is cleaved Another water molecule then attacks the Ca position to ... Analysis ofthe products ofthe reaction revealed the presence of guaiacylglycerol (GG) and 4MU (data not shown) Localization of enzymatic activity To confirm the localization ofthe b-aryl ether...
... 2 on the next page shows thatthe building society lost half of its deposit funding between the end of 2007 andthe end of 2010 and also paid off almost all of its outstanding debt securities. By the end of 2010, Eurosystem borrowings accounted for more than half of its liabilities. ... bank did not have the promissory notes. Thus, a key point to understand about the future cost of IBRC tothe Irish public is that, effectively, the promissory notes only exist to pay off the ELA debts tothe Central Bank of Ireland. ... restructuring ofthe promissory notes that is sold as having the benefit of reducing the €48 billion figure to something lower will actually be doing very little to reduce the long‐term burden ofthe ...
... whereas the label was rarely found near toother sites ofthe podocyte surface (Fig 6D,E) In the cytoplasm the label was quite often found in densities (Fig 6F) that could correspond tothe endoplasmic ... biological ligand of nephrin It is apparent thatthe slit-diaphragm is connected tothe actin cytoskeleton that has a well-documented and critical role in the formation ofthe slit diaphragm and foot ... interactions The function and regulation of nephrin can not be fully understood before the protein complex associated with its intracellular domain is described and characterized There are a number of...
... used The peptide synthesizer used conductance monitoring to check the efficiency ofthe coupling reactions In order to scale up the automated synthesis tothe same level as the manual synthesis ... by the costs ofthe reagents and our desire to obtain peptides that were ofthe highest purity Also, the use of only a slight excess (10–20%) of some expensive amino acids contributed tothe ... contributed tothe very low yields We note also that determination ofthe stereochemistry ofthe 6-bromotryptophan residue as either L or D, and utilization ofthe appropriate resolved precursor would...
... 69.0, 63.4, and 52.6 were higher than the others and were subsequently assigned tothe NeuAc residue Analysis of both ofthe 1H- andthe 13C-NMR spectra using 1D and 2D techniques gave the data ... comparison tothe methylation analysis data on the O-polysaccharide, indicates thatthe terminal NeuAc shouldbe substituting the galactose residue in the 6-position For the full characterization of ... high proportion of heptose may bethe result of short chains It is not a component in the polysaccharide as demonstrated in the MS analysis (see below) The absolute configurations ofthe sugars were...
... aqueous phase and by shaking (in the presence ofthe glass beads) The organic phases were then pooled and evaporated to dryness Next, the lipids were redissolved in 70 lL of chloroform ⁄ methanol ... expected (and as a control), the incorporation of oleoyl-CoA into lysoPA and PA was the same when microsomal membranes isolated from wild-type and psi1D cells were used (synthesis of 80 pmol of PA ... lysoPI and excluding the possibility of a transacylation mechanism from the sn-2 tothe sn-1 position of PI We further carried out experiments to measure the specificity ofthe enzyme in vitro The...
... intensities of these bands corresponded tothe positive reactivity ofthe target protein and may therefore have been degradation products ofthe truncated protein The sensitivity ofthe anti-GST serum to ... likely thatthe epitope is restricted to residues 365–385 ofthe hTF C-lobe The mAb F11 blocked binding of hTF tothe TFR; this suggests the antibody epitope contains residues that are located in the ... either lobe of TF is accompanied by a significant conformational change The current study describes the localization ofthe mAb F11 epitope tothe C-lobe of hTF, specifically to residues 365–401 that...
... the cumulative testimony ofthe experiences of many other believers over the ages, provide for the believer evidence ofthe reality of God and/ or his revelation, andofthetruthof beliefs and ... know thatthe accounts of God andof divine action in the Bible or the Koran are true?’’ The skeptic probes further and tries to understand why the believer believes in the authenticity ofthe ... noting that there are different uses and senses of faith, belief, and reason is not to prefer one sense or usage over another, but to alert us tobe aware ofthe specific sense and usage of these...
... animals are personified, and they are also given the ability tobe able to speak to each other in English The fact that they are able to speak to each other like human beings makes them seem more ... his town gets a job on a steamboat and returns tothe town to show off, the narrator and his friends become so envious that they decide to follow the boy’s example The narrator is determined to ... down there that day Two or three ofthe boys had long been persons of consideration among us because they had been to St Louis once and had a vague general knowledge of its wonders, but the day of...
... repair (4) We speculate that Artemis and NHEJ proteins are recruited tothe integration site (5) These proteins, and likely other factors, then mediate theother steps of post integration repair, ... reaction To distinguish between these possibilities, we took advantage ofthe fact that failure of PIR after integrase-mediated joining of viral and host DNA in other contexts triggers apoptosis ... bottom row) To verify thatthe failure of ATM association with viral DNA in NBS1-deficient cells arises specifically from the mutation in the NBS1 gene, rather than from some other difference between...
... On theother hand, the wide variety of low-risk products offer many options, and people often find it much easier to become used to a new ritual or habit than they think This survey suggests that ... long-term use of pharmaceutical nicotine, there is no reason to believe that these products pose greater risk than ST, so this can be used as a best guess about their effects also Approved usage of existing ... smoking besides just getting nicotine Smoking is important to my social life Reasons for not previously considering switching to ST to stop smoking but continuing to use nicotine1 I believe that...