processes is an increase in angiogenesis always beneficial to the health of the patient
Báo cáo khoa học: Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential doc
Ngày tải lên :
30/03/2014, 08:20
... control substance in this context, because it is an inhibitor of P-glycoprotein rather than MPTP, and is devoid of calcineurin-inhibiting properties [23] We hypothesized that an increase in steady-state ... NIM811 and PSC833 induce an increase in cytosolic [Ca2+] and production of ROS The discrepancy in the effects of PSC833 between GLC4 cells and isolated mitochondria versus the consistency in the ... an increased DWm 3004 [17,20] The CsA analog N-methyl-4-isoleucine-cyclosporin (NIM811) is also known as an inhibitor of MPTP, and to lead to an increase in DWm [21] Fluorescent probes used to...
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Tài liệu Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area ppt
Ngày tải lên :
18/02/2014, 11:20
... indicating that there could be more than one binding site for bis-ANS on HSL (Fig 3A) The maximum emission intensity of the complex increased in an inverse hyper- Fig Interaction of bis-ANS with HSL ... Krintel et al recombinant rat HSL, but are in accordance with the published activity of His-tagged human HSL [11,14] HSL inhibition by bis-ANS To evaluate whether bis-ANS had an effect on the ... (Fig 2) Scavenging of bis-ANS by BSA is presumably the reason for a sigmoidal inhibition curve, rather than the expected hyperbolic one The binding of bis-ANS to HSL followed an inverse hyperbolic...
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Tài liệu Báo cáo khoa học: Lipopolysaccharide-evoked activation of p38 and JNK leads to an increase in ICAM-1 expression in Schwann cells of sciatic nerves ppt
Ngày tải lên :
18/02/2014, 18:20
... of ERK was not significant (Fig 5) Roles of MAPKs in LPS-induced ICAM-1 synthesis Using U0126 (an MEK1 ⁄ inhibitor), SB202190 (a p38 MAPK inhibitor) and SP600125 (an SAPK ⁄ JNK specific inhibitor), ... Technology Guidance Plan for Social Development of Jiangsu Province (grant BS2004526), the Health Project of Jiangsu Province LPS increases ICAM-1 expression in Schwann cells of sciatic nerves (grant H200632), ... lipopolysaccharide (LPS) and in ammatory cytokines, such as tumor necrosis factor-a (TNF-a), interleukin-1b (IL-1b) and interferon-c (IFN-c) [9] LPS is a major constituent of the outer membrane of Gram-negative...
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Báo cáo Y học: Amphipathic property of free thiol group contributes to an increase in the catalytic efficiency of carboxypeptidase Y pot
Ngày tải lên :
08/03/2014, 23:20
... (Cys341) is involved in substrate binding at the S1 subsite and in maintaining the width and depth of the S1 subsite; (b) the rearrangement of the S1 subsite induced by the interaction between the ... lacks the ability to interact with the protonated His397, this mutant enzyme is inefficient at utilizing the increased interaction energy to stabilize the tetrahedral intermediate in the transition ... 2) It is possible that the hydrophobic interaction of Val with other side chains in the S1 pocket or P1 side chain of the substrates in the Michaelis complex inhibits the acylation step in the...
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Báo cáo khoa học: H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae An experimental and theoretical approach pot
Ngày tải lên :
17/03/2014, 10:20
... accompanied by an increase in the rate of synthesis of Ino, without any need to modify the kinetic parameters or activities of the enzymes involved in the pathway from ATP to Ino Being aware of the simplications ... the actual concentration of ATP and hence the rate of synthesis of inosine It is here assumed that the complex processes of syntheses and degradation of ATP in vivo (involving many enzymes) is ... in ATP and the increase in inosine, promoted by H2O2, cannot be explained solely by a change in the level of the enzymes more directly involved in the nucleotide pathway from ATP to inosine (Fig...
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Báo cáo khoa học: The inhibition of Ras farnesylation leads to an increase in p27Kip1 and G1 cell cycle arrest pdf
Ngày tải lên :
31/03/2014, 01:20
... treatment of Rat1/ras cells leads to the accumulation of p27Kip1 in the cyclin E/Cdk2 complex and to the inhibition of its kinase activity 40 some-mediated proteolysis by using LLnL, an inhibitor of the ... D1/Cdk4 and cyclin D1/Cdk6 complexes using anti-(cyclin D1) Igs revealed an HR12-induced increase of p27Kip1 levels in the complexes This was accompanied by increased kinase activity of these immunoprecipitates ... whether or not LLnL was present during the metabolic labelling (Fig 6C) These findings confirm that HR12 does not enhance the rate of p27Kip1 synthesis, indicating that the increase in amounts of...
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– ACT MATH TEST PRACTICE – 74. Choice f is correct. Since YW is an altitude in an equilateral pptx
Ngày tải lên :
18/06/2014, 17:20
... in line 31, the word patina most nearly means: a the pattern of clouds in the sky b the pattern of the elm tree branches c the shine of the sky d the color of the sky Which is the first noise to ... generations to come 51 The migratory path of the Arctic Tern: a varies depending on the year b is from the Arctic to the Antarctic and back to the Arctic c is from the Arctic to the Antarctic d is to the ... sent to school This did not answer any better The rough play of the boys was not to his liking When he saw them drag the wings off butterflies, or torture any animal that fell into their hands, his...
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Báo cáo y học: "P5L mutation in Ank results in an increase in extracellular inorganic pyrophosphate during proliferation and nonmineralizing hypertrophy in stably transduced ATDC5 cells" pdf
Ngày tải lên :
09/08/2014, 08:23
... human chondrocyte cell line (CH-8) demonstrated an increase in the transcription and translation of ANK Among the two missense ANKH mutants studied, neither the P5L mutant nor the M48T mutant ... ank-transduced cell lines (Figure 3c), including the P5L cell line Rather, the results strongly suggest that the increase in ePPi elaboration in the ank-transduced cells during the mineralizing ... into a pcDNA I vector (Invitrogen) containing a FLAG sequence at the amino terminus of the multiple cloning site To generate an inframe FLAG tag, the stop codon of each Ank cDNA – wild type and...
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Báo cáo y học: "Does an increase in body mass index over 10 years affect knee structure in a population-based cohort study of adult women" pot
Ngày tải lên :
12/08/2014, 14:22
... all of the data (including statistical reports and tables) in the study and can take responsibility for the integrity of the data and the accuracy of the data analysis Competing interests The ... collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the article for publication We thank the participants who made this study possible, and the ... Abstracts of the American College of Rheumatology 68th annual meeting and the Association of Rheumatology Health Professionals 39th annual meeting: October 16-21; San Antonio, Texas, USA Arthritis Rheum...
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Báo cáo y học: "Improved lung preservation relates to an increase in tubular myelin-associated surfactant protein A" ppsx
Ngày tải lên :
12/08/2014, 18:21
... and statistical analyses HF participated in the design of the study, the statistical analysis, and drafted the final version of the manuscript MO participated in the design of the study and in ... of the surfactant system Whether the antiinflammatory effect of Celsior is an indirect result of the improved preservation of the surfactant system, the inactivation of which contributes to an ... exocytosis and endocytosis of surfactant were well balanced In contrast, the apical cell surface is expected to grow when more surfactant is secreted than recycled, which is based on the finding...
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Sustaining an Interest in Learning English and Increasing the Motivation to Learn English
Ngày tải lên :
06/09/2013, 10:10
... sustain interest in the use of the language It should be pointed out here that the main emphasis of this enrichment program is more on the process of learning rather than the performance of learning ... purposes) in the context of language learning On the other hand, integrative motivation refers to the desire to learn a language to integrate successfully into the target language community In later ... given an environment (in rural areas) where the English language input is limited and non-conducive to learning the target language, teachers need to find creative ways to teach the language and increase...
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Applying task based approach in teaching english grammar to the 1st year non english majors at ho chi minh university of industry, nghe an branch luận văn thạc sĩ giáo dục học
Ngày tải lên :
18/12/2013, 10:29
... This thesis, therefore, focuses on studying the application of TBL in teaching English grammar to probe its feasibility and validity in the setting of HUI, Nghe An Branch 2.2 The Importance of ... intellectual and reasoning power, and, though challenging, they are engaging and often satisfying to solve It consists of analyzing real situations, analyzing hypothetical situations, reasoning ... roles in discovering and processing knowledge The result of the research is the outcome of task-based learning The idea of getting learners to acquire English through tasks was developed in India...
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how the use of the diary form narrative is beneficial to the
Ngày tải lên :
21/03/2014, 22:04
... and the reader can feel as if they are part of the group and read, and think along with the characters Another thing dealing with the diary form is quick referencing The reader, if needed, can ... person was talking and acting through the written dialects In the novel Dracula, all the diaries, of all the individuals come together and in the end, become one powerful, combination of descriptions, ... when the diary form of narrative is used For instance, after Lucy had written what was happening to her when her mother passed away, the story went back in time for another important matter to...
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Báo cáo Y học: The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains pptx
Ngày tải lên :
23/03/2014, 21:20
... (tryptophan-rich motif), insert into the membrane lipid layer when intact h-toxin binds to the membrane [24] Upon binding to cholesterol-containing membranes, tryptophan fluorescence in all toxin ... of their ability to bind to cholesterol-containing membranes We next examined the cholesterol-binding kinetics of these toxin fragments by surface plasmon resonance using a Fig Isolation of toxin ... which indicates that the environment of the tryptophan residues in the D4 fragment is more exposed to solvent than in the native toxin As no tryptophan is present at the interface of domain with...
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Báo cáo y học: "Survival of TNF antagonists in spondylarthritis is better than in rheumatoid arthritis. Data from the Spanish registry BIOBADASER" docx
Ngày tải lên :
09/08/2014, 08:22
... significant expression of TNF in the entheses and peripheral joints in all the conditions [44-47] This has led to the use of TNF antagonists in the treatment of SpA resistant to NSAIDs and the traditional ... were approved by the Spanish Medicines Agency (Ministerio de Sanidad y Consumo), and the information regarding patients was gathered in the registry and handled according to current official regulations ... of Rheumatology This study was funded, in part, by the Spanish Agency for Medicines and Medical Devices (Ministry of Health, Spain) The following is a list of contributors (and centers) in BIOBADASER,...
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báo cáo khoa học: " An innovative telemedicine knowledge translation program to improve quality of care in intensive care units: protocol for a cluster randomized pragmatic trial" ppsx
Ngày tải lên :
11/08/2014, 16:21
... to the writing of this study protocol We also wish to acknowledge the following individuals for their input into the design of this study: Stephen Lapinsky MD, Sherman Quan, Kevin Thorpe PhD, and ... quality improvement training, and follow-up support to increase the delivery of surfactant therapy to eligible infants[41] Their intervention was highly successful Infants in intervention hospitals ... 4:5 Background The demand for intensive care is increasing because of an aging population and the introduction of new life-sustaining technologies[1] This care is expensive and the necessary resources...
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An investigation into the effectiveness of Vietnamese translation in teaching English vocabulary to the 10th form students at Vung cao Viet Bac High school = Ng
Ngày tải lên :
28/03/2015, 09:35
... procedures of the study Chapter is the analysis and discussion of the findings through an analysis of the data collected by means of questionnaire, classroom observations and interviews Part C is the ... simply defines “translation as the rendering of a written text into another language in the way the author intended in the text.” Translation is the technique of explain the new word by the learner‟s ... getting the learners to repeat the pronunciation of the word, (e) writing the word on the board, (f) pointing out any spelling irregularity in the word Finally, the use of the word can be explain...
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An investigation into the use of group work in teaching speaking skill to the 11th graders at Bo Trach 1 high school
Ngày tải lên :
19/07/2015, 19:05
... changes in English language teaching in the particular are not the changes in the way we teach There are the changes in the aims of language teaching and learning Although there is room for individual ... basing on the color of the clothes they are wearing Changing group: It is better for the students not to stay in the same group, working with the same friends from the beginning to the end of the ... creative ideas to the end solution What’s more, group brainstorming can produce ideas in more depth than individual brainstorming 29 Planning:Planning is another type of group work which involves different...
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Báo cáo y học: "An Avian Connection as a Catalyst to the 1918-1919 Influenza Pandemic"
Ngày tải lên :
02/11/2012, 11:12
... hypothesis, was that the source of the pandemic was an animal virus, which crossed from one species to another to eventually infect humans Supporting Shope’s hypothesis of trans-species infection an ... determined by: the efficiency of the hemagglutinin ability to drift; functional ability of the nueraminidase, and the immunity of the host it infects to fight the virus The first two factors are influenced ... we have to combat influenza is isolation and culling of infected fowls as demonstrated by the government of China, Vietnam, and Thailand As human populations continue to increase and interactions...
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