probing structures and dynamics of the quantized transition states
Báo cáo khoa học: Eukaryotic class 1 translation termination factor eRF1 ) the NMR structure and dynamics of the middle domain involved in triggering ribosome-dependent peptidyl-tRNA hydrolysis pptx
... 1H,15N-HSQC spectra of the M domain of human eRF1 The numbering of the residues corresponds to that of the full eRF1 protein (A) The Gly region of the 15 H, N-HSQC spectrum of the M domain of human eRF1 ... )42 The mean value in the family of 25 structures and the SD is no preferred conformation of the side-chain in the family 4228 v1 b There Fig The relaxation parameters of the amide 15N spin of ... on the equivalent segments of each member of the family of the solution structure of the M domain of human eRF1 The resulting rmsd values (y-axis) and their deviations through the 25 NMR structures...
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Báo cáo y học: "Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species" docx
... have an effect on the estimated value of the mutation rate and on the branch length of the phylogenetic tree However, they not affect the structure of the tree and the estimates of the recombination ... tree obtained using the SNPs of the core genome of the 44 strains of S pneumoniae, strains of S mitis and strain each of S oralis and S infantis For clarity the clade containing the S pneumoniae ... genes, and the genome of the common ancestor of S pneumoniae and S mitis encoded 2,039 genes For comparison, the average number of genes of S pneumoniae is 2,104, and the average number of genes...
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Tài liệu Banks’ exposure to interest rate risk, their earnings from term transformation, and the dynamics of the term structure pptx
... contribution of the systematic factor and the regulation to the total timely variation of the exposure is 17.24% and, therefore, 82.76% of the variation is due to idiosyncratic effects These effects ... disentangle the contributions of the systematic factor and of the regulation One can expect some correlation between the regulatory variables outi (t) and out2i (t) on the one hand, and the variables ... instance, the duration, and the weighted sum of the positions’ duration is a measure of the bank’s exposure to interest rate risk (See, for instance, Sierra and Yeager (2004)) The main problem of these...
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Báo cáo khoa học: Solution structure and backbone dynamics of the XPC-binding domain of the human DNA repair protein hHR23B docx
... further our knowledge with respect to the mechanisms of action of these proteins, it is crucial that we define the precise boundaries of the STI1-homologous domain and compare the structures of these ... [33] The errors of R1 and R2 were estimated from the errors in the single exponential decay fitting, and those of the 15N-1H NOEs were obtained from the difference of two independent experiments The ... 2A) The N-terminal part of XPCB–hHR23B B C Fig NMR structure of the XPCB domain of hHR23B (A) Stereoview of the 12 superimposed structures of XPCB–hHR23B All Pro residues conserved among the...
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Báo cáo khoa học: Intermodule cooperativity in the structure and dynamics of consecutive complement control modules in human C1r Structural biology docx
... parts comprising mainly the b-strands The loops between strands B and C, known as the ‘hypervariable loop‘, D and E, E and F, F and G, and G and H are particularly tolerant of longer insertions ... exactly the reverse of the situation observed for the CCP1single and CCP2single modules and probably reflects the complex interdependence of the modules in terms of internal dynamics and may also ... autoactivation of C1r and the activation of C1s require large-scale movements of the different domains of the proteases Intermodular and intramodular flexibilities are thought to be essential in these...
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Báo cáo khoa học: Microcin J25 induces the opening of the mitochondrial transition pore and cytochrome c release through superoxide generation doc
... inhibit the increase of ROS strongly supports the above-mentioned hypothesis The NADPH oxidation occurs prior to the opening of the MTP pore and is coupled to the transport of calcium from the intermembrane ... mediated by the uptake of calcium through the uniport of calcium On the other hand, KCN and antimycin A, both inhibitors of electron transport, also inhibited the swelling induced by MccJ25 The inhibition ... necessary for activation of the MTP These results indicate that the effect of MccJ25 on the respiratory chain forces the opening of the MTP pore, which is mediated by an increase of the matrix calcium...
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Báo cáo khoa học: Refined solution structure and backbone dynamics of the archaeal MC1 protein ppt
... inwards, the arms close and the tips of the arms wrap around the DNA The amplitudes and time scales of the intramolecular motions experienced by the protein backbone are commonly determined from the ... Dihedral angle and distance transitions as a function of time of the two bulges (A) Bulge Leu8, His16 and Gly17 (B) Bulge Val57, Glu87 and Arg88 (C) Schemes of the bulges The dotted lines and the time ... with the DNA-binding b-hairpin arms of HUs, which showed high mobility relative to the core (Fig 2) The b-ribbon arms wrap around the minor groove of the DNA and, at the tip of each arm, the conserved...
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THE NUCLEAR AND AERIAL DYNAMICS OF THE TUNGUSKA EVENT potx
... depend upon the location of the event and the zenith angle chosen as it represents the vector snm of the Earth’s orbital Nuclear and aerial dynamics of the Tunguska velocity (30 km s-l) with the comet’s ... cP is the specific heat of the gas at constant pressure, y is the ratio of specific heats, c is the speed of sound, (T is the Stefan-Boltzmann constant, pa is the air density and T,, is the temperature ... estimation of the mass lost along the comet’s arbitrary path prior to entry into the Earth’s atmosphere However, to specify the orbit of the comet demands knowledge of both the comet’s eccentricity and...
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Báo cáo khoa học: Functional aspects of the solution structure and dynamics of PAF – a highly-stable antifungal protein from Penicillium chrysogenum pdf
... activity of PAF Differences and similarities between the structures of PAF and AFP The common geometrical arrangement of the two proteins is the special Greek key fold, in which the Structure and dynamics ... mPAF at the respective concentrations of and 100 lgÆmL)1 Fig Ribbon diagram of the mean PAF structure without disulfide bond constraints the core of the protein (Fig 9) As a consequence of the highly-twisted ... contributing to the sheet stabilization (Table 2) The b5 strand is the most negativelycharged region of PAF and close to the C-terminus starts at Ala51 Loop (47–50) connects strands b4 and b5 and creates...
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schumann - dynamics of the bacterial chromosome - structure and function (wiley, 2006)
... involved in the maintenance of the long axis of the cell Depletion of either MreB or Mbl causes aberrant partitioning of the origins of replication and a large fraction of anucleate cells The intermediate ... control the degree of methylation of specific glutamates in the MCPs This resets the signaling state of the chemoreceptors and allows them to adapt to the present concentration of attractant and ... pestis XV Color Plates Structure of the OmpF porin View of the monomer from the side (left) and view of the trimer from the top The loop inside the opening narrows the channel H Nikaido 2003, Microbiol...
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the classical and quantum dynamics of the multispherical nanostructures, 2004, p.400
... sizes of about micron and less The number of theoretical and experimental works on the subjects of microspheres increases every year The most fruitful turns out to be the idea of transition from the ... 2003 and references therein] Despite of high cost of such microspheres, many important and interesting features of wave and quantum effects are already discovered Nevertheless the results of the theorists ... questions of the theory of classical optics and the quantum optics of the spherical multilayer systems are studied In such systems the spatial scales have order magnitudes of the wavelength of radiation...
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bridges the science and art of the worlds most inspiring structures mar 2010
... the thrust to the foot of the cantilever tower, and the two sides of the towers balance each other The downward forces from the towers sit directly on and compress the foundations This idea of ... According to the latest theory the ‘critical number’ of people above which these wobbles will occur depends on the weight of the bridge, its natural frequency, and the amount of damping (i.e the degree ... lengths of rope and pieces of steel or other materials used in a real bridge to find out how strong they are The internal force is acting all along the length of the rope from one of the teams to the...
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báo cáo khoa học: " New insight into the structures and formation of anthocyanic vacuolar inclusions in flower petals" potx
... at the site of anthocyanin biosynthesis, which then bud off the ER and fuse with the tonoplast With regard to the fate of the anthocyanins after transport to the central vacuole, a number of ... groups of secondary metabolites for which there are data on the sub-cellular nature of the biosynthetic enzyme complex and the subsequent transport of the phytochemical product to the site of accumulation ... biosynthesis, has been extensively characterized, and there is also a good understanding of the transcriptional regulation of the structural enzyme genes [3-5] Furthermore, they are one of the...
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Study on failure of surface and interface of the laminated composite structures of a small ship
... Doctor of Philosophy Study on the failure of surface and interface of the laminated composite structures of a small ship The Graduate School of the University of Ulsan Department of Mechanical ... and thesis layout The amount and role of surface in composite boat is quite great The interface decides the strength of structures and outer surface impacts on the working efficiency and aesthetics ... performed similarly All these layers will cure together (Fig 2-1) However, the quality of type of joint depends on the properties of resin and fiber and the mixed rate of them So this bonding is...
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Modelling and simulation of faceted boundary structures and dynamics in FCC crystalline materials
... defect structures A grain boundary has macroscopic degrees of freedom (3 relating to the orientation of the crystallographic axes of one grain to those of the other and to the inclination of the ... cell of FCC lattice where the edges of the cube form the cartesian coordinate axes The FCC lattice has its lattice points at the corners and face centers of the cubic unit cell The length of the ... freedom (3 relating to the orientation of the crystallographic axes of one grain to those of the other and to the inclination of the boundary plane) and microscopic degrees of freedom (corresponding...
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Báo cáo y học: "Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature"
... case of MZ with mirror-imaging of AC in the literature In this case, we describe the second case of MZ with mirror-imaging of AC and discuss the possible clinical implications First, Helland and ... lack of systematic monitoring and follow-up Therefore, a large percentage of patients with AC are probably undiscovered Mirror images, on the other hand, are present in approximately 25% of MZ Therefore, ... consider that it is mandatory to monitor the counterpart of the symptomatic patient with AC as early as possible, irrespective of the absence of symptoms Conflict of Interest The authors have declared...
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Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"
... craniotomy because of the proximity of the sinus to the orbit and the anterior skull base [5] The frequency of bilateral absence of the frontal sinus has been reported in 3-4% to 10% of several populations ... reliability between observers and was 0.86 Fig Unilateral absence of the frontal sinus; on the right, the absence of the frontal sinus, and on the left, the limited aeration of the frontal sinus; axial ... sinuses, although there is only one frontal sinus ostium The size of the sinus and, therefore, its anatomic relationships also depend upon the extent of pneumatization [11] The extent of pneumatization...
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