prl 1 overexpression alters the microrna expression profile of hek293 cells and leads to down regulation of micrornas that target prl 1 and its downstream pathways
báo cáo khoa học: " HC-Pro silencing suppressor significantly alters the gene expression profile in tobacco leaves and flowers" docx
... related 16 28 11 37 29 Expression of genes Protein synthesis related 1 Photosynthesis related 31 42 15 RNA binding 16 Interesting miscellaneous 12 0 10 1 21 65 Unknown function 55 62 29 21 Total ... (DOWN) (UP) (DOWN) Defence related 17 21 12 ROI related Kinases and phosphatases 12 10 12 20 12 Transcriptional regulators 21 28 Protein degradation and proteases 14 Lipases and hydrolases 10 ... http://www.biomedcentral.com /14 71- 2229 /11 /68 the wild type plants The morphology of the flower was variable, but it often differed from the wild type The petals were often fused together and the color of the petals was...
- 16
- 295
- 0
Báo cáo hóa học: " Changes in the gene expression profile of Arabidopsis thaliana after infection with Tobacco etch virus" potx
... 0.63 1. 60 0.27 2.36 0 .1 0.24 0.76 0.03 0.42 6.36 10 -4 1. 17 10 -7 1. 76 10 -4 1. 31 10 -4 1. 34 10 -6 2.84 10 -4 1. 17 10 -7 1. 13 10 -2 1. 77 10 -2 2.79 10 -2 1. 16 10 -2 5.98 10 -3 1. 14 10 -2 1. 33 10 -2 2.75 10 -2 1. 04 10 -3 ... 0.60 0.00 0.34 1. 17 5.99 10 -7 8.94 10 -3 3.70 10 -2 2 .14 10 -6 7.85 10 -4 1. 59 10 -3 1. 97 10 -2 3.67 10 -4 1. 59 10 -3 1. 84 10 -2 1. 03 10 -5 1. 72 10 -3 1. 13 10 -2 3.70 10 -2 1. 12 10 -2 3.79 10 -2 Non-redundant ... (16 ) 3.79 (12 ) 3 .15 (10 ) 8.77 (25) 5. 61 (16 ) 4. 21 (12 ) 4. 21 (12 ) 3.95 (9) 9. 21 ( 21) 2.63 (6) 4.52 (8) 2.26 (4) 3.95 (7) 1. 89 (2) 7 .14 (4) 8.93 (5) 0.57 0.98 0.89 2.06 1. 41 0.87 1. 23 0.44 3 .11 ...
- 11
- 436
- 0
Báo cáo y học: "The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challeng" ppt
... Bhsp65-tolerized rats showed downregulation of Th1 and Th17 (pro-inflammatory) response, and of other mediators of inflammation and angiogenesis, but of the upregulation of IL -10 (anti-inflammatory/ ... DEG related to oxygen metabolism were found in Rec phase We found that the S100 family members, S100A4 (S100a4), S100A9 (S100a9) and S100A 11 (S100a 11) were upregulated before the signs of arthritis ... involves the priming of potentially pathogenic T cells within the draining lymph nodes [14 , 25-28], and these T cells then migrate into the target organ, the joints, to initiate the development of...
- 48
- 317
- 0
Expression of neurogranin tagged with enhanced green fluorescence protein in HEK293 cells and its effects on neuronal signaling
... day 10 (E18) by Northern Blot, reaching a maximum around postnatal day 10 -15 (P10 -15 ) (Watson et al., 19 90) In parallel, Ng protein appeared for the first time at E18 in the amygdala and the ... antisense probe to the GFP open reading frame The results revealed that the 94 nucleotides in the 5’end of the 3’UTR is able to target the fused transcript to extrasomatic regions of cultured neurons ... a total volume of 250 µl including 15 0 µl of purified PCR product, 10 unit of HindIII, 10 unit of BamHI, 25 µl of Buffer E (Promega), 2.5 µl of 10 mg/ml BSA (Bovine Serum Albumin) and H2 O The...
- 129
- 324
- 0
Expression of neurogranin tagged with enhanced green fluorescence protein in HEK293 cells and its effects on neuronal signaling
... day 10 (E18) by Northern Blot, reaching a maximum around postnatal day 10 -15 (P10 -15 ) (Watson et al., 19 90) In parallel, Ng protein appeared for the first time at E18 in the amygdala and the ... antisense probe to the GFP open reading frame The results revealed that the 94 nucleotides in the 5’end of the 3’UTR is able to target the fused transcript to extrasomatic regions of cultured neurons ... a total volume of 250 µl including 15 0 µl of purified PCR product, 10 unit of HindIII, 10 unit of BamHI, 25 µl of Buffer E (Promega), 2.5 µl of 10 mg/ml BSA (Bovine Serum Albumin) and H2 O The...
- 129
- 455
- 0
Báo cáo y học: " Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells" doc
... microarray analysis and experimental setup This work was supported by NIH grant AI353 81 22 23 References 10 11 12 13 14 15 16 17 18 19 20 Blankson JN, Persaud D, Siliciano RF: The challenge of viral reservoirs ... activation of PBLs and resting CD4+ T cells with PHA, a lectin mitogen, induces cell proliferation and the expression of Cyclin T1 and CDK9, components of the Cyclin T1/P-TEFb complex [8,24-27] To examine ... turnover of memory CD4+ T cells contributes to the maintenance of the reservoir, and ongoing virus replication that is below the detection limit may continue to reseed the reservoir in the presence of...
- 14
- 283
- 0
Báo cáo y học: " Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa" docx
... mRNA expression (log2) -1 183 96 18 2 12 4 29c 31 184 18 1a 204 12 5a -2 -3 -4 -5 (b) Relative mRNA expression (log2) 9* 376a 13 8 335 338 13 6 31 -1 106b 12 9- 6 91 3p 26b let-7d -2 Volume 8, Issue 11 , ... photoreceptor outer segments (a) (b) 4 (c) h183 m155 h133a h133b h1 h146a 2 h133b h133a -lg(P value) -lg(P value) -lg(P value) h4 51 a m4 51 h146a h1 h146b a h4 51 h183 m4 51 m96 h96 0 -3 -2 -1 Δlog2(c57 ... degeneration to demonstrate retinal expression of miR-96, miR -18 2, and miR -18 3 in cells other than photoreceptor cells In this case, altered expression of these miRs between wild-type and mutant...
- 12
- 336
- 0
Báo cáo y học: "The developmental expression dynamics of Drosophila melanogaster transcription factors" pptx
... => 7-8 9 -10 => 11 -12 1- 3 => 4-6 7-8 => 9 -10 11 -12 => 13 -16 4-6 => 7-8 9 -10 => 11 -12 TF 10 0 sets of non-TFs Figure Modularity of transcription factors (a) Expression of Twi and Mef2 and their co-occurrence ... http://genomebiology.com/2 010 /11 /4/R40 Page of 14 stages 1- 3 4-6 7-8 9 -10 11 -12 13 -16 (b) 1- 3 4-6 7-8 9 -10 11 -12 13 -16 (a) stages Forkhead early: 46 TFs 12 6 TFs zf-C4 Ets 85 61 47 55 67 82 T-box TFs ... compares to 47 .1% (337 of 715 ) of TFs in the to 30 minute AEL data point of [32], and significant early expression is further supported by the Page of 14 58.7% (429 of 7 31) of expressed TFs in the to...
- 14
- 286
- 0
Parkinson’s disease candidate gene prioritization based on expression profile of midbrain dopaminergic neurons ppsx
... KNA and HHS DG and AM partook in design of the study and made critical comments SV and KNA drafted the manuscript and all authors read and approved the final version Page of 10 11 12 13 14 15 16 ... Chung et al Xq22 .1 PARK 12 ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) NM_0 011 111 12 .1 UBE2K Chung et al 4p14 PARK Ribosomal protein L 11 NM_000975.2 RPL 11 Chung et al 1p36 .1- p35 PARK &7 ... by the loss of function mutations in the PD genes, is due to hindrance to functions of the wild-type forms and that the proper expression of the genes within mesDA neurons is essential to their...
- 5
- 208
- 0
báo cáo khoa học: " Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines" pps
... 2.53E-02 SM 113 34 SM10789 hsa-miR-4 51 1 .19 2.64E-02 hHM0449 71 hsa-miR-23b 1. 17 2.95E-02 miR195 hsa-miR -19 5 1. 16 3.02E-02 SM10 711 hsa-miR-23b 1. 16 3.03E-02 SM10 310 hsa-miR-342 1. 15 3.24E-02 SM10644 ... [14 ], S (9.62E-04 to 3 .11 E-02) [17 ], Es (1. 82E-02) [8] hsa-miR-23a N (1. 69E-03 to 4 .11 E-02) [ 81] , S (8.70E-04 to 4 .11 E-02) [62] hsa-miR-342 N (6.49E-04 to 4 .11 E-02) [15 ], E (2 .13 E-03 to 4 .11 E-02) ... P-value Down- regulated SM108 01 hsa-miR -18 2-AS -1. 54 1. 44E-03 hsa-miR -13 6 -1. 50 2.28E-03 SM10637 hsa-miR- 518 a -1. 45 3.52E-03 hSQ045460 hsa-miR -15 3 -1 -1. 41 5.07E-03 SM 111 15 hsa-miR-520b -1. 38 AT _1 AT_2...
- 18
- 287
- 0
Báo cáo y học: "The distinct clinical profile of chronically critically ill patients: a cohort study" pps
... ± 21 ± 0. 51 37 42 0.33 SOFA 24 hours 7±3 8±3 0.28 McCabe score 1. 2 ± 0.5 1. 3 ± 0.6 0.38 32 ± 32 ± 19 0. 81 Emergency room 38 (59) 16 ( 51) 0.47 Hospital ward 12 (19 ) (16 ) 0.75 Transfer from other ... 16 (20) 56% 8% 17 (11 –39) aNumber of episodes per 1, 000 intensive care unit days bNumber of episodes per 1, 000 days of mechanical ventilation cNumber of episodes per 1, 000 days of urinary catheter ... treatment of 1, 123 patients at a regional weaning center Chest 19 97, 11 1 :16 54 -16 59 29 Sennef MG, Wagner DP, Thompson D: The impact of long-term acute-care facilities on the outcome and cost for...
- 9
- 507
- 0
Báo cáo y học: " Induction of galectin-1 expression by HTLV-I Tax and its impact on HTLV-I infectivity" ppt
... interaction of the gp46 viral protein with its cellular receptor subsequently followed by the polarization of the infected cell cytoskeleton at the site of cell -to- cell contact and the accumulation of ... of transcription factors to binding sites [32] The +1/ +30 region of the galectin -1 gene is well preserved between different species [33] and the upstream (-57/- 31) and downstream elements ( +10 / ... lactosamine residues [20,23] The galectin family is further subdivided into three subfamilies: the prototype, the tandem repeat and the chimera groups [20] Galectin -1 is a member of the prototype...
- 15
- 324
- 0
Báo cáo y học: " MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype" ppt
... and miR -15 5 are highly expressed in Hodgkin, primary mediastinal and diffuse large 93 94 95 96 97 98 99 10 0 10 1 10 2 10 3 10 4 10 5 10 6 10 7 10 8 10 9 11 0 11 1 11 2 11 3 11 4 11 5 11 6 Volume 8, Issue 10 , Article ... miR 13 6 miR−494 miR−368 miR−382 miR−203 11 11 10 10 10 10 12 5 6 6 1 1 1 Chr 15 **/−/− */−/− */−/− **/−/− **/− miR− 211 miR 18 4 miR−7 miR−9* miR−9 13 5 Chr 16 miR 19 3b miR 13 8 31 miR 14 0 33 7 31 ... miR 18 2 miR−96 miR 18 3 miR−335 miR−29a miR−29b 14 14 8 L N G A */− L N G A L N G A **/− 5 6 6 8 8 4 10 10 0 Volume 8, Issue 10 , Article R 214 2 2 1 1 1 15 16 15 8 11 11 11 12 12 12 */− */− L N G...
- 16
- 316
- 0
Sirtuin2 in the CNS expression, functional roles, action mechanism and mutation induced alteration of molecular cell biological properties
... (RPD3) and RPD1 (also known as SIN3, SD 11, and UME4) are two of the earliest yeast HDAC members (Vidal et al., 19 91; Vidal and Gaber, 19 91) The recessive mutations of these two proteins are found to ... of myelin sheath 11 16 Histone deacetylase 17 2 .1 Histone deacetylation: an important modification of histones 17 2.2 Histone deacetylase family proteins 20 2.2 .1 Class I HDACs 21 iii Table of ... formation 11 6 Deacetylase activity loss is not the cause of aggregate formation 11 7 Determinant of aggregate formation 11 8 6 .1 Insolubility, cytoplasmic aggregate formation and cytotoxicity of rSIRT2...
- 180
- 378
- 0
Bovine ovarian hyperstimulation induced changes in expression profile of circulatory miRNA in follicular fluid and blood plasma
... the ovary consists of the growth of competent follicles, the division of granulosa cells, the expansion of the follicular basal lamina, and finally, the formation of the follicular fluid in the ... mice showed downregulation of some miRNAs in the uterus, an estrogen target organ Altogether, this strongly suggests that ERa bound to E2 inhibits the production of a subset of miRNAs The previous ... between the level of Literature review 24 expression of these transcripts and regulatory function of miRNAs Currently, the regulatory function of miRNAs in gene expression stability of granulosa and...
- 138
- 306
- 0
Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"
... head 2w 22.67 1. 53 26.67 1. 53 40.00±4.36 12 .67 1. 53 26.33±0.58 4w 18 .67 1. 53 19 .67 1. 53 29.00 1. 00 9.67±0.58 49.33±2.52*# 6w 11 .67 1. 53 13 .33 1. 53 23.33 1. 53 6.33±0.58 66.33±3. 51* # Note: * P
- 10
- 584
- 0
Tài liệu Báo cáo khoa học: Enlarging the gas access channel to the active site renders the regulatory hydrogenase HupUV of Rhodobacter capsulatus O2 sensitive without affecting its transductory activity docx
... (19 85) Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors Gene 33, 10 3 11 9 Duport C, Meyer C, Naud I & Jouanneau Y (19 94) A new gene expression ... channel in the large subunit HupV (Ile65 and Phe 113 replaced by Val and Leu, respectively) After mutagenesis, the hupUV genes were cloned into the expression vector pSE102 In pSE103 and pOD7, the wild-type ... (mutant) 18 .5 ± 0.6 0.7 ± 0 .1 8.0 ± 0.8 0.3 ± 0 .1 4.7 ± 0 .1 0.2 ± 0 .1 15.6 ± 1. 2 1. 3 ± 0.3 7.0 ± 0.5 0.7 ± 0 .1 4.0 ± 0.2 0.3 ± 0 .1 15.5 ± 1. 7 5.2 ± 1. 3 7.0 ± 0.7 2.5 ± 0.6 3.7 ± 0.5 1. 2 ± 0.5...
- 10
- 513
- 0
Báo cáo khoa học: Lipid-induced conformational transition of the amyloid core fragment Ab(28–35) and its A30G and A30I mutants docx
... + 1. 0057 y = 2. 814 3x + 0.9989 1. 8 y = 5 .12 86x + 1. 0 211 y = 4 .14 29x + 1. 0064 y = 2.7429x + 09786 1. 7 1. 6 1. 6 l0/l l0/l 1. 4 1. 5 1. 4 1. 3 1. 2 1. 2 1. 1 1 0 .1 0.05 0 .15 0.05 [Acrylamide] (mM) C 0 .1 ... WKGIIIGLM 10 22.9 10 23.4 844 .1 1030.3 845.5 10 31. 1 KGIIIGLMW 10 30.8 10 31. 5 DansylKGIIIGLMW 10 78.8 10 79.6 fluidity upon exposure of the vesicles to the peptides [see the 1, 6-diphenyl -1, 3,5-hexatriene ... (mM) C 0 .1 0 .15 [Acrylamide] (mM) A30l y = 5 .15 71x + 1. 0232 y = 3 .16 86x + 0.9 911 1. 8 y = 2.63x + 0.9762 1. 6 l0/l sity and a spectral blue shift of the peak maxima of 14 , and 19 nm for the WT ⁄ W27,...
- 13
- 336
- 0
Báo cáo sinh học: " Complement component C5a Promotes Expression of IL-22 and IL-17 from Human T cells and its Implication in Age-related Macular Degeneratio" potx
... http://www.translational-medicine.com/content/9 /1/ 111 Page of 12 Figure C5a promotes the expression of IL-22 and IL -17 from T cells (A) IL-22 and IL -17 in 3-day culture supernatants of PBMCs from 14 AMD patients and 14 controls ... Translational Medicine 2 011 , 9 :11 1 http://www.translational-medicine.com/content/9 /1/ 111 Moreover, the expression of Phospho-Bad, one of the anti-apoptotic indicators, was increased in CD4+ T cells after ... (Figure 1A) Interestingly, we cannot detect the changes of IFN and IL-4 Liu et al Journal of Translational Medicine 2 011 , 9 :11 1 http://www.translational-medicine.com/content/9 /1/ 111 Page of 12 Table...
- 12
- 389
- 0
Tìm thêm: khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25