preictal spikes in the hippocampus of patients with mesial temporal lobe epilepsy
Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
Ngày tải lên :
25/10/2012, 10:51
... pointes Unlikely Risk of liver injury in conjunction with lipid-lowering agents; risk of bleeding complications in conjunction with antiplatelet agents, warfarin, niacin Induction of CYP3A4 increases ... gabapentin in patients with HCV [55] These findings suggest that valproate can be used for some patients with HCV without adversely affecting ALT levels Obtaining pretreatment baseline ALT levels in ... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of...
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Báo cáo y học: "A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting" pptx
Ngày tải lên :
09/08/2014, 01:21
... subjects received their first dose of aripiprazole at the start of the switching treatment period, the starting dose of which was determined by the investigator After weeks of adverse event (AE)-free ... receiving >20 mg/day Of the 153 patients enrolled in the study, 106 patients (69.2%) were compliant with treatment During the 12-week switching period, no patients received diphenhydramine and ... during the switching treatment phase This finding, coupled with the improvement in QOL ratings, is important as it provides an estimation of the real-world impact of antipsychotic treatment with...
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Báo cáo y học: "Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis" potx
Ngày tải lên :
09/08/2014, 08:22
... zygapophyseal joints in patients with AS [10] In the present study, we first examined whether inflammation in the spine of patients with AS, as detected by histopathology, can be correlated with bone ... highest score of bone marrow infiltation in the histopathological assessment Some of the patients had inflammatory lesions in other parts of the spine, as indicated in Table Page of (page number ... illustration of the anatomy and detection of inflammation in the bone marrow The entire lumbar spine including the zygapophyseal joints and, if available, the thoracic spine was analyzed for increased...
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Báo cáo y học: "Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years" ppt
Ngày tải lên :
09/08/2014, 14:22
... was the principal investigator of the OASIS study and is the principal investigator who assisted in designing the ATLAS study WPM is the principal investigator and assisted in designing the Canadian ... Goldstein N, Braun J, Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy Study Group: Radiographic findings following two years of infliximab therapy in patients with ... based on their experience with musculoskeletal imaging and experience in reading spinal imaging studies of patients with AS However, none of the assessors was familiar with the OASIS films The assessors...
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báo cáo khoa học: " Connectedness of healthcare professionals involved in the treatment of patients with Parkinson’s disease: a social networks study" pot
Ngày tải lên :
10/08/2014, 11:20
... finding should be interpreted in the context of the newly established network One of the aims of ParkinsonNet is to better integrate primary care professionals in the treatment of patients with ... variation of individual network characteristics for all measures in both the network of ‘knowing each other’ and in the network of ‘having professional contact.’ For example, the number of others ... Consistent with the pattern in the total network, mean and maximum values of the network measures were highest in the network of knowing each other Table shows the same 12 measures in the predefined...
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Báo cáo y học: "Improvement in symptoms and signs in the forefoot of patients with rheumatoid arthritis treated with anti-TNF therapy" ppsx
Ngày tải lên :
10/08/2014, 21:24
... sustained The findings further indicate that the use of US imaging of the foot would be more beneficial than clinical examination alone in the refinement of diagnosis and the implementation of ... beneficial in monitoring the progression of active inflammation in rheumatoid arthritis [13] and in the monitoring of biologic therapy [14-16] The aim of this study was to evaluate by means of US, the ... and foot pain and no account was taken of the mechanical forces of foot function during gait as this was not feasible within the confines of our study Others, having investigated the association...
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Báo cáo y học: "B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin" pdf
Ngày tải lên :
12/08/2014, 12:20
... transduction in B cells The interaction with TRAFs induces the nuclear factor (NF)-B signaling pathway, which plays a pivotal role in regulating diverse aspects of immune function, including mediating inflammatory ... difference in detectable levels of BLyS was found in patients with RA (33%) compared with the healthy donor samples (18%) (Table 1) Within the samples containing detectable levels of the three ... form of BLyS The molecular mass of the heterotrimers was confirmed by SEC-MALS mass distribution LS/UV/RI 3-detector analysis Binding kinetics and affinity studies The binding affinities and kinetics...
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Báo cáo y học: " Pro/con clinical debate: The use of prone positioning in the management of patients with acute respiratory distress syndrome" potx
Ngày tải lên :
12/08/2014, 18:21
... common in the group whose position was varied than in the group that remained continuously supine Con: prone positioning is not useful in the management of ARDS patients Gordon Rubenfeld Imagine the ... Finally, intensivists are strongly motivated by the ‘rule of rescue’ Intensivists feel obliged to offer some therapy, any therapy, to a patient in imminent danger of dying [16] As is often the ... lung injury [8] Clinical experience Prone positioning has improved arterial oxygenation in all studies in patients with ARDS that have examined the question, especially in the early phase of illness...
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Báo cáo y học: "Pro/con clinical debate: Are steroids useful in the management of patients with septic shock" ppt
Ngày tải lên :
12/08/2014, 18:21
... useful in the management of septic shock Katherine G Craig and Keith R Walley The debate surrounding the use of corticosteroids in septic patients has continued for over 30 years Two metaanalyses in ... led to a relative risk reduction of almost 30% in patients with septic shock [9] The survival benefit of combination therapy was significant only in patients with blunted response to ACTH stimulation ... groups [8] There is ongoing debate in the literature as to the usefulness of this corticotropin stimulation test in so-called ‘relative adrenal insufficient’ patients, although it may be of prognostic...
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Báo cáo y học: "Pro/con clinical debate: Antibiotics are important in the management of patients with pancreatitis with evidence of pancreatic necrosis" ppt
Ngày tải lên :
12/08/2014, 19:22
... difference in the rate of infection of pancreatic necrosis [4] Pooling of the data from these 183 patients by Bosscha and colleagues in a meta-analysis resulted in a group of 95 patients treated with ... used intravenous and enteral antibiotics (including amphotericin) to achieve decontamination of the gastrointestinal tract for the purpose of possibly decreasing bacterial inoculation of the necrotic ... selective decontamination of the digestive tract Selective decontamination is attractive as it may allow the use of prophylaxis without the risk of inducing superinfections through the use of long-term...
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Báo cáo y học: " Pro/Con Debate: Does recombinant factor VIIa have a role to play in the treatment of patients with acute nontraumatic hemorrhage" ppt
Ngày tải lên :
12/08/2014, 23:24
... associated with off-label use of FVIIa, the majority occurring in trauma patients However, MedWatch is a database for voluntary reporting of observed complications, and therefore the incidence of complications ... (upper gastrointestinal bleeding) without any evidence for the drug’s efficacy and safety The first issue is the off-label use After a single successful report of off-label use of recombinant FVIIa ... Recombinant activated factor VIIa in an unselected series of cases with upper gastrointestinal bleeding Thromb Res 2005, Epub ahead of print 18 Rizoli SB, Chughtai T: The emerging role of recombinant...
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Risk Factors Affecting the Development of Tuberculosis Infection and Disease in Household Contacts of Patients with Pulmonary Tuberculosis pptx
Ngày tải lên :
29/03/2014, 03:20
... the number of male patients was higher in the index cases, but the number of female patients was higher in contacts determined active disease In our opinion, the reason of this findings were that ... presence of cavity in the chest radiograph of index case increased the frequency of TB in household contacts In our country, Kolsuz et al found the frequency of TB in close contact of TB cases ... [7] Chee et al detected a rate of 0.9% TB patients in investigation of 5699 close contacts of 1374 index case in Singapore [8] In their study which they detected TB in 36 children younger than years...
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Báo cáo y học: "Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener’s granulomatosis" pptx
Ngày tải lên :
09/08/2014, 03:24
... unresolved issues is the inability to explain the nonrandom, selected organ injury that defines the WG vasculitis and the concurrent, seemingly random, nature of injury within ‘targeted’ organs ... the infiltrating cells were characterized as macrophages However, a few cells seemed to be endothelial cells This is in line with our recent findings of de novo synthesis of PR-3 in endothelial ... importance of PR-3 in the pathogenesis of WG, we sought to define the expression pattern of PR-3 in lung tissue Materials and methods Patients Normal tissues were obtained from five patients undergoing...
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Báo cáo y học: "A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis" pptx
Ngày tải lên :
09/08/2014, 08:22
... When testing the activity using SF of patients with RA, we found that while the percentage of inhibition of the NPA in the presence of inhibitor III rarely exceeded 10–15%, the level of inhibition ... microspheres, thereby minimizing interference with debris (Figure 1a, left panel) The NPA in the clinical sample is then obtained by measuring the mean fluorescence intensity resulting from the loss of ... simply the presence of proteases, in patients during the course of their disease and under the influence of treatment This may represent a sine qua non to achieve clinical success in the development...
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Báo cáo y học: " Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis" pdf
Ngày tải lên :
12/08/2014, 18:20
... correspond to the C-terminal half of the CDC25-like catalytic domain in the signaling protein[1] The second most frequent isoform was variant which results in the loss of 69 of these same amino acids ... protein levels This finding would open a new insight in the field of monocyte-lineage cell biology and of the diseases where this lineage cells play a prominent role In the latter part of the ... levels of the hRasGRP4 transcript in each sample One of the healthy individuals was assigned to determine the value of In all of the healthy individuals and patients, assays were done in a triplicate...
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Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf
Ngày tải lên :
18/02/2014, 18:20
... concentrations of several chemokines Chemokines in the joints of patients Table Chemokines and chemokine receptors expressed in the joint of RA patients Systemic name CC chemokines CCL2 CCL3 ... cytokines, including IL-1b, TNF-a and IFN-c (B) Chemokines expressed in the joint recruit leukocytes into the joints In addition to functioning in cell trafficking, several chemokines have other biological ... et al Chemokines in the joints of patients CXC chemokines C and CX3C chemokines Interleukin-8 ⁄ CXCL8 (a ligand of CXCR1 and CXCR2) was the first chemokine identified to be involved in leukocyte...
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The management of patients with venous leg ulcers: Audit Protocol ppt
Ngày tải lên :
15/03/2014, 23:20
... of occurrence of the first ulcer; the site of the ulcers and of any previous ulcers; the number of previous episodes of ulceration; the time taken to heal in previous episodes; the time free of ... bacteria but rather to avoid cross-infection with sources of contamination – for example, other sites of patient or other patients A trial of clean versus aseptic technique in the cleansing of tracheotomy ... Appendix Instructions for Audit Form Which patients are included in this audit? Patients diagnosed with venous leg ulcers are included in the project This includes new patients, patients who are in the...
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Báo cáo khoa học: Role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells docx
Ngày tải lên :
23/03/2014, 10:21
... analyzed the role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells The key role played by gangliosides in defining the distribution of ErbB2 into signaling ... ester-induced disruption of the CD4–Lck complex occurs within a detergent-resistant microdomain of the plasma membrane Involvement of the translocation of activated protein kinase C isoforms ... specifically interact with the purified recombinant extracellular domain of EGFR [22] and that this tyrosine kinase receptor contains a structural domain with targeting information for lipid domains [23]...
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báo cáo hóa học:" A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study" pdf
Ngày tải lên :
18/06/2014, 15:20
... patients with abdominal surgery but without signs of infection or inflammation Secondly, an evaluation of the association of the MIF polymorphisms with the survival of severe sepsis patients was performed ... and co workers these differences may reflect the clinical heterogeneity in patients with infectious diseases Finally, Yende and co workers recruited their individuals in the northeastern United ... association of the -173 SNP genotype C/C with the incidence of sepsis in African Americans but not in European Americans [38] However, because of the limited sample size of -173 C/C individuals in Gao's...
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báo cáo hóa học: " The effect of consequent exposure of stress and dermal application of low doses of chlorpyrifos on the expression of glial fibrillary acidic protein in the hippocampus of adult mice" pptx
Ngày tải lên :
20/06/2014, 00:20
... of Cornu Ammonis of hippocampus The study aimed to look into the changes in the above parameters with reference to our previous findings [8] with dermal application of subtoxic doses of CPF with ... [17,18] The effect of dermal application of CPF on GFAP expression in the hippocampus has not been reported The aim of this study was to determine the expression of GFAP in the hippocampal region of ... adhered to the principles stated in the guide-book of laboratory animal care and user committee of the International Medical University and in accordance with the declaration of Helsinki The mice...
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