positive and negative regulators of the vasopressin gene promoter in small cell lung cancer
Báo cáo khoa học: Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii ppt
... of 1CEL (+1, +2 and +3) are proposed to assist in the binding and positioning of the substrate and play a role in the recognition of the reducing end of the cellulose chain Arginine side-chains ... article presents the first report on the purification and 3D structural determination of a native core CBH protein, and of the cloning and over-expression of the corresponding gene, from a thermophilic ... b-sandwich are composed of seven b-strands Many of the side-chains in the b-sheets are hydrophobic, and interactions between these residues appear to hold the b-sandwich in position With the...
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Báo cáo hóa học: " Trichloroethylene exposure and somatic mutations of the VHL gene in patients with Renal Cell Carcinoma" potx
... least one gene should be altered in both forms This has been confirmed with the cloning of the VHL gene and the identification of germline and somatic mutations of this gene in VHL patients and sporadic ... paraffin-embedded tissue fixed in Bouin's and 23 in formalin solution The majority of the tumours were of the clear cell RCC subtype: 46 were solid clear cell RCC and were cystic clear cell RCC DNA extraction ... tumours For all of the frozen samples the VHL gene was successfully PCR amplified and sequenced, compared to 71% (12 of 17) of the formalin-fixed samples, and 38% (10 of 26) of the Bouin's fixed tissues...
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báo cáo khoa học: " Highs and lows: patterns of use, positive and negative effects of benzylpiperazine-containing party pills (BZP-party pills) amongst young people in New Zealand" doc
... home, having a few drinks at home then going to town and then taking the party pills when you get there Or maybe having a party at home or something, drinking alcohol and then maybe having one ... jaw, and an inability to urinate Others mentioned less often included impaired sexual performance, dizziness, sore eyes, stomach pains, teeth grinding, increased rates of smoking, and bleeding ... and route of administration The main route of administration for interviewees was swallowing BZP-party pills in their original form All participants stated that this was their primary means of...
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Báo cáo sinh học: " Cloning and expression profiling of the VLDLR gene associated with egg performance in duck (Anas platyrhynchos)" docx
... (S-D-E) and eight cysteine-rich repeats within the ligand binding domain; (ii) five YWXD motifs in the EGF precursor homology domain; (iii) an O-linked sugar domain with clustered serine and threonine ... sequence in the putative transmembrane domain and (v) a FDNPVY sequence in the cytoplasmic domain at the C- terminus [3-7,9] The VLDLR-b form lacks the Olinked sugar domain To investigate the evolutionary ... ligand binding motifs within the ligand domain are underlined; YWXD repeats are indicated by a thick underline two mutations at 231 bp (i.e at position 2025 bp of the ORF) and 633 bp (i.e in intron...
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A contrastive analysis of semantic and pragmatic features of the words denoting birds in english and vietnamese
... study of the WDBs contributes to the interesting phenomenon in language In daily communication, people present recognition of the field And the findings of semantic aspects often borrow the WDBs ... implications An investigation into semantic and fields as well as pragmatic features of the WDBs The finding of the pragmatic features of the WDBs leads both teachers and learners of study may be in one ... a study of the semantic and pragmatic the same image or meaning of these words If we both have different features of the WDBs in English and Vietnamese However, there are meanings in mind for...
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Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... all-alpha domain, STAT protein DNA-binding domain and SH2 domain of stat6, and the zinc-finger domain, leucine-zipper domain and fork-head domain of foxp3 In addition, for stat6 and foxp3, there were ... haematopoietic cells and more variably in other lineages [41] The expression of T-bet has been seen within a wide variety of tissues and cells in the Ginbuna crucian carp [27] and, in mammals, in the lung ... implicated in other protein–protein interactions, a STAT protein DNA-binding domain and an SH2 domain, which binds phosphorylated tyrosine residues in the context of a longer peptide motif within a...
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Tài liệu Báo cáo Y học: Analyses of the CYP11B gene family in the guinea pig suggest the existence of a primordial CYP11B gene with aldosterone synthase activity docx
... compared to (intron 7) to (intron 6) for the remaining introns Finally, the 3¢ UTRs of the guinea pig CYP11B genes show only 42% similarity whereas the 3¢UTR of the guinea pig CYP11B2 gene shares ... evolution and function of the hormonal system We first cloned the genes of the CYP11B family of the guinea pig The 11bhydroxylase of the guinea pig showed higher substrate specificity than the aldosterone ... proteins of other species than CYP11B1 of the guinea pig (compare lines A and B) Together these results suggest that the CYP11B2 genes are the primordial genes and that a common ancestor containing both...
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Báo cáo khoa học: Contributions to catalysis and potential interactions of the three catalytic domains in a contiguous trimeric creatine kinase doc
... substrate binding are shown in blue, and the N-terminal ‘hinge’ proline is shown in pink The highly conserved reactive cysteine residues that were the mutagenic target of this study are shown in green ... whereby the closing of one active site exerts pressure through a suite of atomic interactions to inhibit the binding and closing of any other active sites that are in communication with the closed ... constraints imposed upon it by both domains and Domains and 3, on the other hand, only experience the constraints from domain 2, which explains two results seen in analysis of kcat values: the lower...
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Báo cáo khoa học: Regulation of the expression and subcellular localization of the taurine transporter TauT in mouse NIH3T3 fibroblasts doc
... as the product of the rate constant and the cellular taurine pool In the case where TauT activity was down-regulated and preloading of the cells was impossible, the activity of the swelling-induced ... taurine uptake in NIH3T3 mouse fibroblasts is linear within the initial 20 following the addition of 14C-labelled taurine Using taurine uptake within the initial 20 in NaCl medium containing extracellular ... for the taurine efflux (min)1) at each time point was estimated as the negative slope of the graph between the time point and the proceeding time point The taurine efflux at a given time point...
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Báo cáo lâm nghiệp: "A change in structural diversity and regeneration processes of the spruce virgin forest in Nefcerka NNR (TANAP) in relation to altitude" docx
... spruce natural forest in the whole height profile of the virgin forest The testing of the influence of the altitude revealed its great influence in the growth stage In the optimum and breakdown stages ... difference in the index was confirmed in the spruce virgin forest in the altitudinal range of 1,300–1,400 m The analysis of the structure of the spruce virgin forest in Nefcerka NNR assessed according ... m The structure of the virgin forest is very heterogeneous in this altitudinal zone The number of the individuals from natural regeneration (individuals of the height below 130 cm) is declining...
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Báo cáo y học: "The biological and clinical importance of the ‘new generation’ cytokines in rheumatic diseases" pot
... detectable in RA and SLE patient sera and in the synovial tissues of RA patients Inhibition of IL-21 or gene targeting of IL-21 mediates the suppression of a variety of models, including CIA and several ... receptor chain with high affinity (1011/M) and slow off-rate, rendering it a useful and specific inhibitor in biologic systems Common γ-chain signalling cytokines – interleukin-15 and interleukin-21 ... activation in joint inflammation Indeed, the administration of sST2 decreased the production of inflammatory cytokines and the severity of collagen-induced arthritis (CIA) [27] Mice deficient in ST2...
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báo cáo khoa học: " Comparison of KRAS and EGFR gene status between primary non-small cell lung cancer and local lymph node metastases: implications for clinical practice" pdf
... metastases The types and locations of the mutations in paired tumors were shown in Table Thirteen cases of the in- frame deletions in exon 19 and eight cases of point mutation in exon 21 were found in the ... mutations in the lymph nodes included fourteen cases of the in- frame deletions in exon 19 and twelve cases of the point mutation in exon 21 All point mutations found in those samples were Leucin to ... analyze KRAS gene status in primary tumors and their matched metastases They found that the use of ME-PCR allowed a resolution of the discordance in of the cases by demonstrating the presence of low...
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báo cáo khoa học: " Expression profiling and integrative analysis of the CESA/CSL superfamily in rice" doc
... expressed in the tissues we examined, confirming their major roles in the biosynthesis of cellulose, the main component of plant cell walls The co-expression profiling of the CESA genes can somehow indicate ... family of CSLD genes is highest in the stamen and lowest in the shoot of seedlings with two tillers The total expression of the CSLA genes was highest in plumules (mostly contributed by CSLA1 and ... Page of 16 Figure Unrooted tree of OsCESA/CSL protein family (A) and organization of exons and introns of the corresponding genes (B) Tandem and segmental genome duplications of OsCESA/ CSL The...
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báo cáo khoa học: " Unexpected complexity of the Aquaporin gene family in the moss Physcomitrella patens" pdf
... affecting the permeability of the pore since the orientation of the arginine of the ar/R filter is also stabilised by a hydrogen bond to the backbone of the C-loop (Fig 5) Interestingly all the ... [40] and Lienard et al [41] and the remaining 11 are previously not described in the literature The gene structure of the PpMIPs supports the phylogenetic analyses and the resulting division into ... (TIPs), the nodulin-26 like intrinsic proteins (NIPs), the small basic intrinsic proteins (SIPs) and the GlpF-like intrinsic protein (GIPs) [7,16,20] The GIPs have so far only been identified in Physcomitrella...
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Báo cáo sinh học: " Genetic and morphological characterisation of the Ankole Longhorn cattle in the African Great Lakes region" pptx
... (i.e centre of gravity of the landmarks) and each of the configured landmarks Then, the centroids of all the landmark configurations are superimposed and translated to the origin The landmark configurations ... from the sub-populations of Malagarasi also in Tanzania and that of Mugamba in Burundi The structuring and relatedness of the cattle of the sub-populations of Rwanda and that of Busoni in Burundi ... rescaled and aligned coordinates of the eight landmarks of the body Genetic and morphological characterisation of the Ankole cattle 473 Figure (a) Landmarks defining the shape of the head: landmark...
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Ontogeny and hormonal regulation of alpha amylase gene expression in seabass larvae, lates calcarifer
... upon DNA-binding The principle is outlined in the Figure At the beginning of amplification, the reaction mixture contains the denatured DNA, the primers, and unbounded dye; therefore minimal background ... Studies of the binding of GR DBD to several variants of GRE from the TAT gene have led to a conclusion that protein-protein interactions and not changes in the structure of DNA are the major determinants ... shown that two molecules of the GR DNA-binding domain (DBD) bind to a GRE in a cooperative manner (Fig.1.5), in which binding of the first molecule enhances binding of the second (Dahlman-Wright,...
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A study on syntactic and semantic features of the thinking verb group in english and their vietnamese equivalents
... Pointing out the syntactic and semantic features of the THINKINGverbs in English and their Vietnamese equivalents Finding outthe similarities and differences of the THINKING verbs in English and ... discussed the discusses the definition of the mind and similarities and the differences between verbs of thinking and speaking Susanna Karlsson (2008), Re-thinking THINK in contrastive perspective The ... background of analyzing the syntactic and semantic features of the THINKING verbs in English Moreover, the definition of the verb and classification of verb are pointed out in details.Finally, theoretical...
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Báo cáo Y học: Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types pptx
... Alternatively the cells were left in the presence of the antibody for the complete length of this period In both cases the result was the same As shown in Fig 7, the ligation of the CD53 expressing cells, ... transfection there was a displacement of the fluorescence peak, and 45% of the cells where within the positive window (Fig 4) Therefore, as these transiently transfected 293T cells express the CD53 ... quantification of the increase in incorporation of radioactivity detected in the GST–ATF2 fusion protein with respect to the HA epitope The results are the mean of four independent experiments with the...
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Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt
... of Polo-Like Kinase Evaluation of the results obtained in the two systems showed deregulation of the same pathways in human SCLC and in that induced experimentally by the E6/E7 oncoproteins of ... detected in lung tumor cells but not in the adjacent noninvolved lung tissue [9] HPV 16/18 have been detected in the blood of women with cervical infection suggesting that HPV 16/18 can infect the lung ... the average reported incidences is 17% and 15%, respectively, the mean incidence of HPVs in Asian lung cancer is 35.7% The authors concluded that HPV may be the second leading cause of lung cancer...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... parameters/NTCP models The total normal lung volume was defined as the total lung volume minus the primary GTV and volume of the trachea and main bronchi From each lung DVH, the following dosimetric ... patterns, and survival in five Radiation Therapy Oncology Group (RTOG) trials of sequential and/ or concurrent chemotherapy and radiotherapy for locally advanced nonsmall -cell carcinoma of the lung Int ... cally; the incidences of SARP in the group with NTCP > 4.2% and NTCP ≤ 4.2% were 43.5% and 1.4%, respectively (p < 0.01) The incidences of SARP in the group with V10 ≤ 50% and V10 >50% were 5.7% and...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose