... (Std Dev.) 20.0% 25.0% - 19 Portfolio Risk and Return Assume a two-stock portfolio with $50,000 in Alta Inds and $50,000 in Repo Men ^ and σ Calculate rp p - 20 Portfolio Return, ^p r ^ is a ... either stock (20% and 13.4%) average of Alta and Repo (16.7%) The portfolio provides average return but much lower risk The key here is negative correlation 4 - 23 Two-Stock Portfolios Two ... Risk 35 Stand-Alone Risk, σ p 20 Market Risk 10 20 30 40 2,000+ # Stocks in Portfolio - 27 Stand-alone Market Diversifiable = risk + risk risk Market risk is that part of a security’s stand-alone...
... receiving radical surgery and postoperative radiotherapy between Oct 1999 and Dec 2004 were enrolled Patients in pathological stages II, III and IV were 16.5%, 16.5% and 67%, respectively For ... Contributions CYL, AJC and JTC prepared the study concept and design CYL did the major manuscript writing AJC and JTC did the major revision of the manuscript CYL, YLL and TYL made the major ... Epidemiological studies have shown strong associations between ORC and the use of tobacco, alcohol and betel quid [2] The standard treatment for ORC is radical surgery [3] Postoperative radiotherapy...
... protein methylation Adox, lyzed and fractionated in nuclear (lanes and 4) and cytoplasmic (lanes and 3) fractions Ki-1 ⁄ 57 was immunoprecipitated (lanes 1–4) and then submitted to methylation ... methylation of Ki-1 ⁄ 57 and CGI-55 by PRMT1 The interaction of Ki-1 ⁄ 57 with PRMT1 and the presence and conservation of the RGG ⁄ RXR box motifs in the amino acid sequences of Ki-1 ⁄ 57 and CGI-55 suggest ... side) and the gel was exposed to a X-ray film PRMT1 itself and RACK1 served as control proteins (B) In vivo methylation assay: L540 Hodgkin-analogous cells were (lanes and 2) or were not (lanes and...
... into collagenases (MMP-1, -8, and -13), gelatinases (MMP-2 and 9), stromelysins (MMP-3 and 10), matrilysins (MMP-7 and 26), and the membranetype MMPs (MMP-14 to 17 and 24) Furthermore MMPs are ... analyzes and drafted the manuscript LM participated in the design of the study and performed RT-PCR studies SK and SG participated in the design of the study, evaluated cancer samples, and helped ... manuscript CR and LS participated in the design of the study, and performed immunohistochemistry studies AH helped to draft the manuscript CO and GCT participated in the design of the study design and...
... (1 and 10 ng/ml), IL-17 (10 and 100 ng/ml), and PGE2 (0.1 and μM), and the expression levels of PPARγ1 were determined by Western blotting As shown in Figure 4, and like IL-1, TNF-α, IL-17, and ... IL-17 and prostaglandin E2 on PPARγ1 protein expression in osteoarthritis chondrocytes Cells were treated with IL-1 (100 pg/ml), TNF-α (1 and 10 ng/ml), IL-17 (10 and 100 ng/ml), and prostaglandin ... Natural and synthetic ligands of PPARγ were shown to inhibit the expression of several inflammatory and catabolic genes in cultured chondrocytes [4,11,12] and to exhibit anti-inflammatory and chondroprotective...
... showing that intrathecal administration of IL1 and TNFα in healthy rodents induces hyperalgesia and allodynia [8-13], and enhances both the acute response and the wind-up activity of dorsal horn neurons ... Animals were housed five per cage under standard laboratory conditions and were given food and water ad libitum With the purpose of knowing the monoarthritic and hyperalgesic condition of the rats, ... scores in the MP group 20 and 40 minutes Figure Effect of IL-1β on C-reflex integrated activity in propentofylline -and saline-treated normal and monoarthritic rats (NS, MS, NP, and MP groups) (a) groups)...
... expresses CD4, CCR5 and CXCR4 and contains HIV-1 LTR-driven E coli β-galactosidase and firefly luciferase reporter cassette that are activated by HIV-1 Tat expression CHO and CHO-gp120/gp41 [13] ... and revising the manuscript DZ produced Env-coding plasmids and stably transfected cell lines, did fusion complexes preparation and analysis, conceived the study and carried out its design, and, ... Western blot and FACS analysis, cellular fusions and pseudovirus infections experiments PR carried out sequencing, pseudovirus preparation and titration and fusion complexes preparation and analysis...
... underlined An EF-hand consensus sequence is placed between the aligned EF-hand I and EF-hand II sequences [3] The helices are shown as boxes with conserved hydrophobic (h) and other amino acids ... calcium-binding ligands are designated by their coordinates: x, y, z, -y, -x and -z [60] Residues discussed in the text are given in bold (G34, K60 and G81 of CR I –II and G29, G66, R68, G71 and G74 of ... occurred and a lower band, most probably GST, was observed We observed that CR, but not GST (also the lower bands of lanes and 3), binds 45 Ca under the conditions used GST–CR(1–60) and GST–...
... cần thiết thực TÀI LIỆU THAM KHẢO FAO - UNESCO, 1998 Word reference based for soil resources Food and agriculture organization of the united Nation, Rome SANCHEZ, P A., C A PALM, W BUOL, 2003 Fertility...
... to candidates and political parties, and payroll and per diem expenditures The attached Summary highlights the audit objectives and conclusions We more fully discuss the audit objectives and ... disclosure law requirements and adherence to applicable expenditure limits; and administers the State Elections Campaign fund distributions to qualified state candidates and the state committees ... concluded that the Campaign Finance and Public Disclosure Board properly recorded, allocated, and distributed State Elections Campaign funds to eligible candidates and state committees of political...
... out, and cancellations are estimated Source: Minnesota Accounting and Procurement System and Capitol Area Architectural and Planning Board appropriation documentation Capitol Area Architectural and ... Architectural and Planning Board in 1967 Its organization and purpose are defined in Minn Stat Section 15.50 In part, the Legislature established the board to “preserve and enhance the dignity, beauty, and ... Architectural and Planning Board in 1967 Its organization and purpose are defined in Minn Stat Section 15.50 In part, the Legislature established the board to “preserve and enhance the dignity, beauty, and...
... Capitol Area Architectural and Planning Board Chapter Payroll Expenditures Chapter Conclusions The Capitol Area Architectural and Planning Board appropriately processed and recorded payroll expenditure ... gain an understanding of the payroll and personnel process We analyzed payroll expenditure levels to determine proper recording of payroll transactions We also reviewed salaries and separation ... contract provisions 11 Capitol Area Architectural and Planning Board Conclusions The Capitol Area Architectural and Planning Board appropriately processed and recorded payroll expenditure transactions...
... IL-1α and IL-1β, are considered the major effectors of injury, and inhibiting their signalling with the IL-1 receptor antagonist (IL-1Ra) is protective in experimental models of stroke [1], and ... immune studies and analysis KJK contributed to the design and execution of the surgical studies GLC contributed experimentally DB contributed to design and analysis of the study and wrote the ... design and analysis of the study and wrote the manuscript All authors read and approved the final manuscript Acknowledgements This work was funded by the Wellcome Trust (DB, NML, GLC), and by...
... in standard doses at three weekly intervals [Cyclophosphamide 500 mg/m2, Adriamycin 50 mg/m2(methotrexate in cardiotoxic patients) and 5-FU 500 mg/m2] All cases were re-assessed clinically and ... of locally advanced carcinoma (i.e stage IIb and stage III) The age of the patients ranged from 32-85 years with a mean age of 47.3 years and a standard deviation of 10.98 years (Table 1) Majority ... “false negative cases”, one was a “non responder” that was N2 (both pre and post NACT) and the other was a responder (pre NACT-N2 and post NACT-N1) i.e Both false negative cases were not N0 after three...
... Adesida et al Figure from non-FGF2 and FGF2 expanded meniscus aggregate cultures Proteoglycan gene expression in monolayer andcells from non-FGF2 and FGF2 expanded meniscus cells Gene expression ... oxygen tension In nonFGF2-expanded cells COL2A1 increased 60-fold and SOX9 12-fold, whereas COL2A1 increased 80,000-fold and SOX9 80-fold in FGF2-expanded cells (Figures and 3) However, the 80,000-fold ... L-SOX5 and SOX6 in cell aggregates derived from FGF2-expanded meniscus cells (Figure 2) Aggrecan is the predominant proteoglycan of cartilage and inner meniscus, and decorin, biglycan and fibromodulin...
... (granitoid) and extrusives (rhyolite, andesite, dacite and probably andesito-basalt) Resting on this hard ground, lays a complex of deltaic deposit (95% of 30,000sqkm) true delta, two floodplains and ... agriculture, forestry (mainly mangrove), fish farming, industry (cementery, lime kiln and ceramics), land use and civil engineering Trang ... vực phía Nam năm 2005 THE SEDIMENTO-GEOLOGICAL MAP OF THE MEKONG RIVER DELTA – SCALE :1/100.000 – AND ITS APPLICATION ABSTRACT The Mekong Delta in VietNam is one of the largest continental recent...
... polyubiquitination and proteasomal degradation Several E3 ligases including Cul5 [17], Nedd4, and AIP4 [18], have been reported to induce Vif ubiquitination, and the roles of Cul5 for Vif ubiquitination and ... reagents, analyzed data, and wrote the paper ATK designed research, analyzed data, wrote the paper, and organized the research KS, KIo, and MM prepared the materials and performed a part of the ... mediates p53 ubiquitination and degradation [20]), Cul5 (another RING finger type E3 that forms a complex with Vif and is reported to induce Vif ubiquitination [17,21]), and Parkin (another RING...
... wanted to go What makes Napster and Popular Power and Freenet and AIMster and Groove similar is that they are all leveraging previously unused resources, by tolerating and even working with variable ... design, and this multimedia future was to be made up of professionally produced CD-ROMs and "walled garden" online services such as CompuServe and Delphi And then the Web came along and let absolute ... Understand the theory, study the engineering, but most importantly, follow the adoption rate The cleanest theoryand the best engineering in the world mean nothing if the users don't use them, and...