polyphenols in human health and disease pdf
Báo cáo khoa học: Regulation of matrix metalloproteinase activity in health and disease pdf
Ngày tải lên :
15/03/2014, 00:20
... integrin-binding ligand
N-linked glycoprotein (SIBLING)
Individual members of the SIBLING family are known
to bind strongly to both pro- and active forms of
specific MMPs. Bone sialoprotein binds ... proMMP-binding partners
involved in activation.
Allosteric activation
Gelatinase interactions with collagen and gelatin
Binding of macromolecules or specific thiol-binding
reagents to an MMP with an intact ... activation by binding to
the 64 kDa intermediate form of MMP-2 [52]. Binding
and activation of MMP-2 was abrogated in the pres-
ence of avb3 integrin-binding macromolecules such as
vitronectin and HKa...
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Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
Ngày tải lên :
14/02/2014, 18:20
... mutation in the BTK PH domain; arginine 28 is in
dark blue, encircled in red. Bottom left: SH2 domain. Right: kinase
domain. The mutated residues are indicated in yellow, a-helices are
in cyan, ... T-cell kinase (ITK) could in uence the infectivity of HIV
and also have anti -in ammatory activity. Since 2006, several patients carry-
ing a fusion protein, originating from a translocation joining ... Holland J, Davies
A, Flinter F, Hammarstrom L, Kinnon C, Levinsky
R, Bobrow M et al. (1993) The gene involved in
X-linked agammaglobulinaemia is a member of the src
family of protein-tyrosine kinases....
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf
Ngày tải lên :
16/02/2014, 14:20
... proteins. Thus, the MEN1 ⁄ LEDGF-interacting
domain linked to DNA-binding domains (AT-hook and
MT domain) becomes disconnected from the PHD
domains, the FYRN domain, the transactivating
domain, ... 2010)
doi:10.1111/j.1742-4658.2010.07608.x
The increasing number of chromosomal rearrangements involving the
human MLL gene, in combination with differences in clinical behavior and
outcome for MLL-rearranged ... proteins. The common denominator in all
different MLL rearrangements is disruption of the MLL
protein in a region that prevents any subsequent pro-
tein–protein interaction between the resulting...
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Modern Nutrition in Health and Disease pot
Ngày tải lên :
06/03/2014, 05:21
... myofibrillar protein from tissues containing myosin and actin (muscle,
smooth muscle such as gut, skin). In man, 3-methylhistidine is quantitatively excreted into urine; in rat, 3-methylhistidine is also ... of Free Amino Acids in the Body
It is important to bear in mind the differences in the relative amounts of N contained in extracellular and intracellular amino acid pools and in protein itself. ... to measure arginine kinetics in pediatric burn patients and
determined little net de novo arginine synthesis, suggesting that under conditions of burn injury, insufficient arginine is made to...
- 1.2K
- 1.1K
- 2
Báo cáo khoa học: Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types pdf
Ngày tải lên :
06/03/2014, 22:21
... erythrocytes,
and the difference between acetylcholinesterases of kid-
ney and erythrocytes in the extent of binding with the
lectins concanavalin A, Lens culinaris agglutinin
(LCA), and Ricinus communis ... of
Alzheimer’s disease in the brain in vivo.
Neurobiol Aging doi:10.1016/j.neurobiolaging.2010.04.
028.
26 Vidal CJ (2005) Expression of cholinesterases in brain
and non-brain tumours. Chem Biol Interact ... in oligomers [11]. Five 5¢-alternative acetyl-
cholinesterase mRNAs have been identified in mice and
three in humans [11,12], and acetylcholinesterase-H,
acetylcholinesterase-T and acetylcholinesterase-R
mRNAs...
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Báo cáo khoa học: Nuclear localization of human spermine oxidase isoforms – possible implications in drug response and disease etiology pptx
Ngày tải lên :
07/03/2014, 05:20
... decreases in intracellular spermine pools
and increased spermidine levels in SMO1 and SMO5
cells. These changes in spermine and spermidine levels
in both SMO1 and SMO5 overexpressing cell lines
were ... (1991)
Correlations between polyamine analogue-induced
increases in spermidine ⁄ spermine N1-acetyltransferase
activity, polyamine pool depletion, and growth inhibi-
tion in human melanoma cell lines. Cancer Res ... the
oxidation of spermine to spermidine diminishes nuclear
spermine pools. Because spermine has essential roles in
the the protection of DNA, including free radical scav-
enging and DNA shielding, this reduction...
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The Neuronal Environment: Brain Homeostasis in Health and Disease pot
Ngày tải lên :
15/03/2014, 19:20
... and mRNA binding to cytosolic and poly-
some proteins in brain and peripheral tissues. Brain Res. Mol. Brain Res. 58, 170–177.
39. Lauger, P. (1991) Na,K-ATPase, in Electrogenic Ion Pumps, Sinauer, ... HOMEOSTASIS AND NEUROLOGICAL DISEASE
Substantial progress has been made in the understanding of the pathophysiology and
mechanisms involved in the attenuation of brain homeostasis. In many diseases ... metabolites and to remove waste products.
The Neuronal Environment: Brain Homeostasis in Health and Disease
examines the function of all the components involved, including their perturbation dur-
ing...
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Báo cáo khoa học: Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans ppt
Ngày tải lên :
15/03/2014, 23:20
... modulated by lumican-evoked signaling,
including vinculin and focal adhesion kinase [82].
Lumican alters the relationship between actin filaments
and b1 integrin, which in turn would affect focal adhe-
sion ... with the EGF-binding domain [32]. The
structural constraints of the EGFR binding region
support a stochiometry of 1 : 1 for the decorin pro-
tein core and EGFR, suggesting that decorin is bio-
logically ... leucine-rich proteoglycans (SLRPs) are involved in many aspects
of mammalian biology, both in health and disease. They are now being rec-
ognized as key signaling molecules with an expanding...
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Báo cáo khoa học: Proteoglycans in health and disease: the multiple roles of syndecan shedding ppt
Ngày tải lên :
15/03/2014, 23:20
... motif) that maintains them as inactive
zymogens, and a catalytic domain with a z inc-binding site
(Zn, HEXXHXXGXXH) and a conserved methionine
(Met-turn) supporting the catalytic zinc. Interaction
between ... (GAIP)-interacting C-terminus ⁄
synectin and calc ium ⁄ calmodulin-associated serine kinase,
since the C2 region contains a class II PSD-95 ⁄
Discs-large ⁄ Zonula occludens protein-binding motif
FXF, ... cysteine–zinc maintains proMMPs in an inac-
tive state by preventing a water molecule from binding
to the zinc atom. All MMPs, with the exception
of MMP-7, MMP-23 and MMP-26, also contain a
hemopexin-like...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
Ngày tải lên :
15/03/2014, 23:20
... Accumulating evidences indicate that
HSPGs act to inhibit cellular invasion by promoting
tight cell–cell and cell–ECM interactions, and by main-
taining the structural integrity and self-assembly ... signaling.
Expression of HSulf-1 in cell lines derived from head
and neck carcinoma inhibits cell growth, motility and
invasion in vitro [17]. Similarly, overexpression of
HSulf-1 and HSulf-2 in ... the
seemingly distinct protein domains observed in the 3D
model, namely the TIM-barrel and C-domain regions,
mediate enzymatic and nonenzymatic functions of hep-
aranase, respectively. Interestingly,...
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Poultry health and disease control in developing countries doc
Ngày tải lên :
17/03/2014, 10:20
... pivotal roles in
the poultry industry, through protecting both poultry and human
health (see Information Note on “Veterinary Roles in Health and
Knowledge Transfer across a Poultry Industry”).
The ...
developing industry. The interfacing of industry and government
poultry health production activities can then help to drive both
(Bagust, 1999; Information Note on “Veterinary Roles in Health
and ... health and disease control in developing countries
Information Note on “Site Biosecurity and Supporting Strategies
for Disease Control and Prevention”) work together to reduce
the risk of introduction...
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THE HEALTH PROMOTING SCHOOL: INTERNATIONAL ADVANCES IN THEORY, EVALUATION AND PRACTICE pdf
Ngày tải lên :
22/03/2014, 15:20
... issues
related to maintaining adolescents’ health and well-being’ – suggesting that
the school has a role to play in helping parents understand some of the key
health challenges facing young people.
Section ... Research in the Finnish ENHP Schools
Kerttu Tossavainen, Hannele Turunen and Harri Vertio
291 15 The Views of School Health Nurses on Promoting the Health and
Well-Being of Young People in Finnish ... well being. There is little
doubt that teaching is a demanding profession, and if schools take seriously the
health promoting school philosophy, the health and well being of teachers –
and other...
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The Maternal Management of Children, in Health and Disease ppt
Ngày tải lên :
23/03/2014, 02:20
... child, and induce a state of body deficient in vigour, and unfit for maintaining full
health: scrofula and other diseases would be induced. At the same time let the mother guard against
pampering, ... quantity, and as a consequence of this
process being interrupted, the food passing on into the bowel undigested, will there ferment and become sour,
will inevitably produce cholic and purging, and in ... effectually to prevent indigestion, and bowel complaints, and the irritable condition of the nervous
system, so common in infancy, and secure to the infant healthy nutrition, and consequent strength...
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- human health and disease notes pdf
- human health and disease pdf
- memmlers human body in health and disease pdf
- human genome sequencing in health and disease pdf
- natural antioxidants in human health and disease pdf
- human body in health and disease pdf
- human microbiome in health and disease pdf
- human health and disease ncert pdf
- antioxidants in human health and disease pdf
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