... any GB (Rhodes and < /b> Hanson 1993) Genetic evidence that GB improves salinity tolerance has been obtained for many important agronomical crops such as tobacco, tomato, potato, barley, maize, and < /b> ... withstand high soil salinity and < /b> saline water irrigation, phytoremediation and < /b> wetland restoration It will be invaluable to < /b> develop these strategies to < /b> ensure sustainability, and < /b> future efforts to < /b> ... Environment basically consists of balanced interaction between biotic and < /b> abiotic factors, and < /b> often abrupt perturbations in abiotic factors surrounding the biotic organisms lead to < /b> change the homeostasis,...
... probes) and < /b> subjected to < /b> 8% SDS ⁄ PAGE and < /b> western blotting, the membranes were probed with : 1000 phosphotyrosine mAb (PT66) and < /b> InR -b antibody or : 500 EGFR antibody (CF4) in Tris-buffered ... responsible for PKB phosphorytion [26], and < /b> PKN is another substrate of PDK-1 related to < /b> cytoskeleton and < /b> transcription factor [27] Figure 4E,F shows that the PDK-1 protein was upregulated to < /b> 162 and < /b> ... 2006 FEBS Q Wang et al because a reduction in rictor or mammalian TOR (mTOR) expression inhibited the signaling of PKB Rictor–mTOR complex can also facilitate the phosphorylation of PKB-T308 by PDK-1...
... nuclear factor-kappa B nuclear binding and < /b> is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha J Immunol 1998, 161(2):1007-16 Tripp RA: The brume surrounding respiratory syncytial ... to < /b> altered Th1-type cytokine and < /b> chemokine expression by BAL cells [55], and < /b> can inhibit TNFα signaling [13] Taken together, RSV surface proteins have immune modulatory features that appear to < /b> ... and < /b> analyzed or stored at 4°C prior to < /b> staining Cells were permeabilized with 1× BD Perm/Wash™ and < /b> stained with either rabbit anti-SOCS1 polyclonal antibody or goat antiSOCS3 polyclonal antibodies...
... discussions and < /b> valuable suggestions, and < /b> GenExel and < /b> the Bloomington stock center for fly stocks This work was supported by grants from the Swiss National Science Foundation and < /b> the Kanton of Zürich ... IGF-binding protein-related protein (IGFBP-rP1/MAC25) Diabetes 2006, 55:2333-2339 Burger AM, Leyland-Jones B, Banerjee K, Spyropoulos DD, Seth AK: Essential roles of IGFBP-3 and < /b> IGFBP-rP1 in breast ... construct, Ch Hugentobler, A Baer, A Straessle, P Gast and < /b> B Bruehlmann for technical support, J Reiling for critical reading of the manuscript, E Brunner and < /b> the members of the Hafen lab for helpful...
... correlation between midkine and < /b> albumin; similarly between both BMI loss and < /b> plasma leptin levels; and < /b> BMI loss and < /b> midkine There was significantly positive correlation between BMI loss and < /b> VEGF-A; ... pro -and < /b> anti-inflammatory cytokines and < /b> vascular-related molecules by tumor necrosis factor-α blockade in patients with rheumatoidarthritis J Rheumatol 2005, 32:2102-8 Muramatsu T: Midkine and < /b> ... an-easyto measure and < /b> well-standardized outcome predictor [35,36] Similar to < /b> substantial weight loss [10], an elevation in CRP concentration has been related to < /b> increased extent of primary tumor and...
... tube growth New Phytol 2007, 174:742-751 11 He JM, Bai XL, Wang RB, Cao B, She XP: The involvement of nitric oxide in ultraviolet -B- inhibited pollen germination and < /b> tube growth of Paulownia tomentosa ... provide a causal link between NO generated by pollen and < /b> this decrease in H2O2 levels This and < /b> some other possibilities of signalling cross-talk between pollen and < /b> stigma have yet to < /b> be investigated ... Arabidopsis flowers, senescence has been connected with low levels of ascorbic acid and < /b> therefore alterations of the endogenous levels of both giberelic and < /b> abscisic acid [47] In addition to...
... DUNG Tổng quan hàm b m Ứng dụng hàm b m Hàm b m ảnh số Các b ớc b m ảnh số Các phương pháp b m ảnh số Ứng dụng b m ảnh số Demo chương trình trang Tổng quan hàm b m Hàm b m thuật to< /b> n không dùng ... ký số Thay ký to< /b> n tài liệu ký đại diện tài liệu tạo từ hàm b m Hàm b m dùng để xác định tính to< /b> n vẹn liệu Hàm b m dùng để b o mật số tài liệu đặc biệt ví dụ b o vệ mật khẩu, b o vệ khóa mật ... sử dụng cho b m ảnh số Đây b ớc có nhiều b o, nghiên cứu đề xuất phương pháp để lấy nét đặc trừng ảnh Randomization Trong b ớc liệu vector lấy từ b ớc Freature Extraction tạo b m việc sử...
... replaced by a second methyl group in CH3SCH3 The enhancement of the S atoms proton-accepting ability strengthens the NHãããS H-bond to < /b> the point where it is the sole contributor to < /b> the global minimum ... CO p orbital, surprisingly strong for what amounts to < /b> an SHãããp H-bond This complex also contains a secondary CHãããS H-bond, which allows the S atom to < /b> serve as both proton donor and < /b> acceptor An ... S lone pairs to < /b> the CO p* The next two minima (pictured in Figure S2) are also stabiantibonding orbital The O atom serves as proton acceptor for lized by CHãããO H-bonds, followed by a weaker complex,...
... reported to < /b> be induced by the MAPK signaling pathway In the human B- cell line Ramos, miR-155 is induced by signaling by the B- cell receptor through the ERK and < /b> c-Jun N-terminal kinase pathways but ... animal development and < /b> functions as a master regulator of cerebellar granule cell progenitors (GPCs) Medulloblastoma (MB) is the most common pediatric brain malignancy and < /b> is caused by the disruption ... in the feedback control of nuclear factor kappa B (NF-jB)-dependent responses < /b> by inhibiting the expression of NFKB1 in human polymorphonuclear neutrophils [51] Feedback regulation by miRNAs in...
... (2001) MLL and < /b> CREB bind cooperatively to < /b> the nuclear coactivator CREB-binding protein Mol Cell Biol 21, 2249–2258 Rozenblatt-Rosen O, Rozovskaia T, Burakov D, Sedkov Y, Tillib S, Blechman J, ... includes a DNA-binding domain, a ligand-binding domain and < /b> a transactivation domain The DNA-binding domain is responsible for DNA binding specificity and < /b> dimerization, and < /b> the ligand-binding domain ... transcription factors is likely to < /b> be similar in both the basal and < /b> activated transcription environment, the requirement for accessory factors (activators and < /b> coactivators, repressors and < /b> corepressor) may...
... initially become rounded, which is accompanied or followed by membrane blebbing, resulting in small vesicles termed apoptotic bodies Inside the cell, apoptosis is characterized by condensation and < /b> ... transduction pathways activated by stress and < /b> inflammation Physiol Rev 81, 807–869 Pearson G, Robinson F, Beers GibsonT, Xu BE, Karandikar M, Berman K & Cobb MH (2001) Mitogen-activated protein (MAP) ... plasmid, and < /b> total cell lysates were analyzed by immunoblotting with a phospho-specific antibody to < /b> JNK Sorbitol treatment (500 mM) was included as a positive control Total levels of JNK and < /b> JSP1...
... Ser9-phosphorylated GSK 3b (GSK 3b- PS9), total GSK 3b, active ⁄ dephosphorylated b- catenin, total b- catenin and < /b> collagen-I and < /b> cell proliferation in lung fibroblasts Lung fibroblasts HFL1 were incubated with or ... kinase, total p38 MAP kinase, Thr390-phosphorylated GSK 3b (GSK 3b- P-T390), total GSK 3b, active ⁄ dephosphorylated b- catenin, total b- catenin and < /b> collagen-I and < /b> cell proliferation in lung fibroblasts ... dephosphorylated b- catenin, total b- catenin and < /b> collagen-I in lung fibroblasts Lung fibroblasts HFL1 were incubated with or without a-defensin-1 and < /b> a-defensin-2 (2.5 lM) in the presence and < /b> absence of...
... would be possible to < /b> dissect points which could be targeted by pharmacological inhibitors For example, mouse embryonic stem cells have been shown to < /b> be hypersensitive to < /b> apoptosis triggered by DNA ... sugar-phosphate backbone (black circles–pink lines) and < /b> expanded manifold beyond the scale, is the only base in mammalian chromosomes which is stably modified by methylation at the carbon-5 position ... (HDAC9), histone chaperones (ASF1A and < /b> NPM2), DNMT1 and < /b> several Polycomb group proteins (BMI1, EED and < /b> EZH2) Several recent studies have linked Polycomb proteins to < /b> abnormal DNA methylation and < /b> DNA...
... recognizes, binds and,< /b> in most cases, stabilizes labile mRNAs Thus, information about mRNA stability may contribute to < /b> osmosensory signal transduction Unfortunately, we know nothing about the role ... fishes represent excellent models to < /b> identify and < /b> understand elements and < /b> mechanisms controlling the physiological < /b> and < /b> behavioral changes that occur in response to < /b> osmotic stress The three major ... aquatic vertebrates such as fishes are also sensed via perception of concomitant fluid volume and < /b> ⁄ or blood pressure changes Systemic osmosensors and < /b> baroreceptors are responsible for monitoring plasma...
... contributes to < /b> the entire response to < /b> insulin [5] In general, cell swelling stimulates anabolic metabolism and < /b> proliferation and < /b> provides cytoprotection, whereas cellular shrinkage leads to < /b> catabolism ... plasma membrane (caveolae), intracellular organelles, ligandindependent activation of growth factor- and < /b> cytokine receptors and < /b> autocrine stimulation of signal transduction by release of mediators ... intracellular Na+ may be one of the first components of the mitogenic signal Direct detection by 23Na-NMR spectroscopy in quiescent 3T3 mouse fibroblasts stimulated by growth factors Biochim Biophys Acta...
... (Z-GGR-AMC) was from Bachem (Bubendorf, Switzerland); recombinant human tissue factor from Dade Behring (Marburg, Germany); and < /b> human thrombin calibrator from Synapse (Maastricht, the Netherlands) InsP3 ... pathway, which leads to < /b> aIIbb3 integrin activation and < /b> platelet aggregation [18] We and < /b> others have shown that both the PI3-Kb and < /b> PI3-Kc isoforms contribute to < /b> the P2Y12-mediated stabilization of platelet ... phospholipase C activity and < /b> Ca2+ mobilization in a way controlled by PI3-Kb Results Autocrine and < /b> added ADP increases and < /b> prolongs thrombin receptor-induced Ca2+ responses < /b> via P2Y12 receptor stimulation...
... of aB-crystallin both aA- and < /b> aB-crystallin possess at least two binding modes, and < /b> that these are influenced by both external factors (e.g changes in temperature and < /b> pH) and < /b> intrinsic factors ... fibril formation by a-synucleinA53T is inhibited by aB-crystallin, and < /b> this chaperone activity is enhanced by Lys-HCl, Arg-HCl and < /b> Gdn-HCl Fibril formation was induced by incubating a-synucleinA53T ... hydrochloride (Lys-HCl), to < /b> test whether any effects were attributable to < /b> adding a basic amino acid; and < /b> (c) Gdn-HCl, to < /b> test whether any effects of Arg-HCl were attributable to < /b> the guanidinium group...
... fractions The IR also binds to < /b> Grb7 and < /b> Grb10, two adaptor proteins that are structurally related to < /b> Grb14, and < /b> besides the IR, the epidermal growth factor (EGF), fibroblast growth factor and < /b> platelet-derived ... with the PIR–BPS of Grb14 and < /b> of the Grb14 SH2 domain have allowed us to < /b> propose a model for the Grb14–IR interaction The PIR–BPS binds as a pseudosubstrate inhibitor in the substratebinding groove ... was observed between phosphorylated IRb and < /b> Grb14 (r = 0.81, P < 0.01) Comparable effects of bpV(phen) treatment on IRb phosphorylation and < /b> Grb14 content, albeit less marked, were also observed...
... not resemble the MAN1 siRNA phenotype, e.g., TGFb signaling was not enhanced [17] TGFb/BMP signaling: the basics BMP, TGFb and < /b> activin belong to < /b> a family of pleiotropic cytokines Each cytokine ... cancer, fibrosis and < /b> autoimmune disorders Signaling is initiated by binding of the cytokine to < /b> a homodimeric complex of cytokine receptor type II, which recruits type I receptor and < /b> activates it by ... and < /b> barrier to < /b> autointegration factor (BAF) compete for binding to < /b> emerin in vitro J Biol Chem 278, 6969–6975 Mansharamani M & Wilson KL (2005) Nuclear membrane protein MAN1: Direct binding to...