... pharmacovigilanceinanindustry setting – the European Union M O’Gorman 177 209 65 12 PharmacovigilanceintheUS – anindustryperspective T.M Hodge 231 91 13 Practical veterinary pharmacovigilance D ... conduct of pharmacovigilance activities K Grein Veterinary pharmacovigilancein France G Keck and X Pineau Pharmacovigilancein Germany C Ibrahim and A Wilke Veterinary pharmacovigilance – the UK ... syringe when filling or giving the injection, and animals should always be properly restrained when administering the medicine The VPC published a letter inthe Veterinary Record highlighting the...
... Illinois, Indiana, and Ohio in 1998 and in trials in Italy and France in 1999 Grain and forage samples were taken from plants of the corn event NK603 and the non-modified control both years Inthe ... within the single insert, are intact; an inversely linked 217 bp piece of DNA containing a portion of the enhancer region of the rice actin promoter at the 3’ end of the inserted DNA Sequencing ... 1993) and in corn (Dean et al., 1986) Given the structure of the cp4 epsps coding sequence, the surrounding genetic elements and the nature of the plant’s protein-producing machinery, any transcripts...
... [36] Thus, lowering the salt concentration could improve the antimicrobial activity of the ASL in two ways: increasing the individual action of the factors, and augmenting synergism between them ... SM, Singh PK, Welsh MJ: Antimicrobial peptides and proteins inthe innate defense of the airway surface Curr Opin Immunol 2001, 13:89-95 Lehrer RI, Ganz T: Antimicrobial peptides in mammalian and ... experimental animals or humans Osmotic agents such as hypertonic saline, which is ionic, and nonionic mannitol, dextran and lactose, have been used in human subjects to increase mucus clearance [1823]...
... drotrecogin alfa (activated) infusion may reduce risk for both bleeding and ICH Eli Lilly and Company: XigrisTM [package insert] Indianapolis, IN: Eli Lilly and Company; 2001 Angus DC, Linde-Zwirble ... initiation of infusion in all clinical trials Intracranial hemorrhage type During infusion period During postinfusion period Total Parenchymal1 14 20 Subarachnoid 1 Subdural 1 Other/undetermined ... using investigator assignment of causality (related or not related) and by comparing events that occurred during the infusion period with events that occurred postinfusion The study drug infusion...
... current, the erosion is taking away the small grains causing the coarsening of the grain size of the beach According to the geology investigation document of the Hydraulics Engineering Survey and ... is one of the main national channels connecting the seaway to the inland waterway system Lots of sand has been dredging in order to maintain the shipping channel Erosion situation: At the locations ... (April to October) The heaviest rainfall occurs in August and September, causing intensive flooding inthe delta due to overflow of the riverbanks The winter is cool and dry, with mean monthly temperatures...
... indicates their usefulness in a realistic modeling and processing of uncertainty and Chapter Introduction imprecision 1.2 Modeling of Uncertainty and Imprecision The distinction between uncertainty and ... with the aid of random variables, random processes or random fields using the probability theory and statistical methods Generally, randomness arises inan underlying random experiment where random ... Plausibility P l(·) and belief Bel(·) for the uncertain thickness t 1.2.3.2 Interval probabilities In contrast to the evidence theory, the quantification of information using the concept of interval...
... Danshen prolonged the prothrombin time of warfarin, an indicator of anti-coagulation inthe rat (Lo et al 1992) ; increased the bioavailability and decreased the elimination of warfarin inthe ... wrongly used during the manufacturing process, suggesting the lack of stringent good manufacturing practice and inadequate quality control on the part of the manufacturer The proliferation of the ... system and is exploring new ways to bring the ancient practice of Chinese medicine in line with modern standards (Liu and Salmon 2010) The crucial issues relating to the safety of the herbal medicines...
... reproduced in any form by any electronic or mechanical means (including photocopying, recording, or information storage and retrieval) without permission in writing from RAND Published 2007 by the RAND ... Progress and Maintaining Vigilance Figure S.1 The Components of an Effective Patient Safety System The component for monitoring progress and maintaining vigilance is identified first and placed on the ... generous with their time and information, enabling us to gain a comprehensive understanding of the growing volume of patient safety activities occurring inthe field and of AHRQ’s contribution to them...
... training a workforce skilled in safety) and adopting effective practices THE CHANGING CONTEXT DURING THE INITIATIVE The formation and funding of the AHRQ patient safety initiative occurred inan ... Progress and Maintaining Vigilance Figure S.1 The Components of an Effective Patient Safety System The component for monitoring progress and maintaining vigilance is identified first and placed on the ... and the Resource Center, and integrating them whenever possible, including the joint conduct of the annual conferences for the two groups of grantees AHRQ PATIENT SAFETY PROJECTS Since enacting...
... of the cases As independent factors the distance between the isocenter and the initial tumor margin (the higher the distance the lower the dose, p = 0.0004) as well as the geometry of the initial ... according to the distance to the margin of the originating metastases across readers The difference between the doses measured inthe group ≤ mm (in median 13.18 Gy) and > 15 mm (in median 11.85 ... radiotherapy exceeds the CTV substantially [3] In CT-guided brachytherapy the catheters are positioned and fixed inside the tumor Hence, organ motion is not a limiting factor and the CTV and PTV...
... chronic infectious diseases associated with viruses and intracellular pathogens, and also for the development of therapeutic vaccines against cancer In this study, we determined the adjuvanticities ... when used in conjunction with non-specific immunoadjuvants [3-5] enhancing either humoral and/or cellular responses against an immunogen Moreover, their inclusion in vaccine formulations can engender ... exacerbated by many commonly used adjuvants Assessment of anti-phthalate and cross-reactive anti-DNA antibody responses inthe presence of various adjuvants is thus a novel approach for evaluating the safety...
... data analysis, and inthe revising and final approval of the manuscript Competing interests TS is a research fellow inthe Norwegian Air Ambulance Foundation SS has no competing financial interests ... was involved inthe study conception and design, acquisition of data and data analysis, and the drafting, revising, and final approval of the manuscript SS was involved inthe study conception and ... the mechanism of injury for all patients According to local procedures and international Utstein Guidelines, key variables important in determining mechanism of injury (MOI) in MVA patients include...
... of pregnant women in Korea J Parasitol 2008; 94: 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians Emerg Infect Dis ... infections among persons infected with the human immunodeficiency virus Clin Infect Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk factors associated ... References Angulo FJ, Glaser CA, Juranek DD et al Caring for pets of immunocompromised persons Can Vet J 1995; 36: 217-222 Glaser CA, Angulo FJ, Rooney JA Animal-associated opportunistic infections...
... studies in Industry, where they are exposed to the working methods and requirements of jobs at industry or other institutions while applying the knowledge they are acquiring, thus gaining experience ... discourage staff from working with industryThe difficulty of striking the right balance between teaching and research on the one hand and consultant on the other Industry has problems in terms of • • ... Engineering and Manufacturing (Industry) Firms inthe private and state-owned sectors in Vietnam are mostly medium and small They have not enough money for possessing their own in- house R&D Therefore,...
... for the listening Focus on assessing the listening skills, not spelling, grammar etc Include both detail questions and meaning questions Don’t expect full comprehension Consider integrating skills ... make inferences using real-world knowledge predict outcomes and infer connections distinguish between literal and implied meanings use non-verbal clues to assist comprehension use listening strategies ... you want to try out? ASSESS THE LISTENING TEST Assess the Listening test in your handout • What are the strengths of this test? • What are the weaknesses? • How would you design a test using this...
... 4oS and long 111oE, 116oE It is bounded to the northwest by the province of West Kalimantan, to the northeast by East Kalimantan, to the southeast by South Kalimantan, and to the southwest by the ... concentrations inthe river water were lower than the maximum limit of the Indonesian drinking water standard, except in one tributary sample The mercury concentrations in sediments were lower than the USEPA ... (19 inthe Kahayan River and its tributaries and 10 inthe Rungan River and its one tributary) Samples were taken from the Kahayan River on three occasions between 2004 and 2007 Inthe Rungan...
... shown in this study, the careful monitoring of organophosphorus pesticides and their oxides in aqueous environment and in tap water is an important matter for health assessment from the viewpoint ... Martí I and Ventura F (2001) Monitoring of pesticides in drinking and related waters in NE Spain with a multiresidue SPE-GC-MS method including an estimation of the uncertainty of the analytical ... (Woburn, MA, USA) The microsomal enzyme solution contained recombinant human CYP, human CYP reductase, and human cytochrome b5, which were expressed from cDNA using baculovirus-infected insect cells...