pharmacology of acute lymphoblastic leukemia therapy

CLINICAL EPIDEMIOLOGY OF ACUTE LYMPHOBLASTIC LEUKEMIA - FROM THE MOLECULES TO THE CLINIC docx

... infections and risk of acute lymphoblastic leukemia in the offspring American journal of epidemiology 2003;158(3) 207-213 Infectious Etiology of Childhood Acute Lymphoblastic Leukemia, Hypotheses ... experience and the risk of childhood acute lymphoblastic leukemia American journal of epi‐ demiology 2000; 152(5):1136-44 Model for Identifying the Etiology of Acute Lymphoblastic Leukemia in Children ... Epidemiology of Acute Lymphoblastic Leukemia - From the Molecules to the Clinic Figure Interaction among the three phenomena Acute lymphoblastic leukemia (AL) in childhood is the result of the interactions...

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Báo cáo khoa học: "Mitochondrial DNA alterations of peripheral lymphocytes in acute lymphoblastic leukemia patients undergoing total body irradiation therapy" ppt

Danh mục: Báo cáo khoa học

... alterations of peripheral lymphocytes in acute lymphoblastic leukemia patients undergoing total body irradiation therapy Quan Wen1, Yide Hu1§, Fuyun Ji2, Guisheng Qian2 Third Department of Oncology, ... Comparison of intensive chemotherapy, allogeneic or autologous stem cell transplantation as post-remission treatment for adult patients with high-risk acute lymphoblastic leukemia Final results of the ... rate of 4.5-4.9 cGy/min over two successive days None of the patients had prior exposure to any cytotoxic treatment for at least weeks before the start of radiotherapy All patients had ml of PB...

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Báo cáo y học: " Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia" ppt

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... children with acute lymphoblastic leukemia Leukemia 2001, 15:74-79 Schmiegelow K, Forestier E, Hellebostad M, et al: Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic ... of relapse for some children with acute lymphoblastic leukemia J Clin Oncol 2003, 21:1332-1339 Cunningham L, Aplenc R: Pharmacogenetics of acute lymphoblastic leukemia treatment response Expert ... chemotherapy for childhood acute lymphoblastic leukemia N Engl J Med 1998, 338:499-505 17 Erb N, Harms DO, Janka-Schaub G: Pharmacokinetics and metabolism of thiopurines in children with acute lymphoblastic...

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báo cáo hóa học: " Health-related quality of life assessment in Indonesian childhood acute lymphoblastic leukemia" potx

Danh mục: Hóa học - Dầu khí

... quality of life in survivors of childhood cancer in Uruguay Pediatr Blood Cancer 2008, 50:838-43 Sutaryo , Sumadiono , Suhadi , et al.: The Protocol of Wijaya Kusuma acute lymphoblastic leukemia of ... Survival of childhood acute lymphoblastic leukemia: experience in Chennai J Trop Pediatr 1999, 45:367-70 Metzger ML, Howard SC, Fu LC, Pena A, Stefan R, Hancock ML, et al.: Outcome of childhood acute ... acute lymphoblastic leukemia (ALL) Pediatr Blood Cancer 2006, 46:35-9 Varni JW, Limbers CA, Burwinkle TM: Parent proxy-report of their children's health-related quality of life: an analysis of...

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báo cáo hóa học: " Impaired sleep affects quality of life in children during maintenance treatment for acute lymphoblastic leukemia: an exploratory study" pdf

Danh mục: Hóa học - Dầu khí

... Feeny D: Health-related quality of life during post-induction chemotherapy in children with acute lymphoblastic leukemia in remission: An influence of corticosteroid therapy Int J Oncol 1997, 11(2):333-339 ... 38(2):119-126 33 Marchese VG, Chiarello LA, Lange BJ: Effects of physical therapy intervention for children with acute lymphoblastic leukemia Pediatr Blood Cancer 2004, 42(2):127-133 34 Meeske ... ALL: Acute lymphoblastic leukemia; CHQ: Child Health Questionnaire; CSHQ: Children’s Sleep Habits Questionnaire; IQR: Inter quartile range; PedsQL: Pediatric Quality of Life Inventory 3.0™ Acute...

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báo cáo hóa học:" Health-related quality of life assessment in Indonesian childhood acute lymphoblastic leukemia" docx

Danh mục: Hóa học - Dầu khí

... quality of life in survivors of childhood cancer in Uruguay Pediatr Blood Cancer 2008, 50:838-43 Sutaryo , Sumadiono , Suhadi , et al.: The Protocol of Wijaya Kusuma acute lymphoblastic leukemia of ... Survival of childhood acute lymphoblastic leukemia: experience in Chennai J Trop Pediatr 1999, 45:367-70 Metzger ML, Howard SC, Fu LC, Pena A, Stefan R, Hancock ML, et al.: Outcome of childhood acute ... acute lymphoblastic leukemia (ALL) Pediatr Blood Cancer 2006, 46:35-9 Varni JW, Limbers CA, Burwinkle TM: Parent proxy-report of their children's health-related quality of life: an analysis of...

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báo cáo khoa học: " Plasma levels of leptin and soluble leptin receptor and polymorphisms of leptin gene -18G A and leptin receptor genes K109R and Q223R, in survivors of childhood acute lymphoblastic leukemia" docx

Danh mục: Báo cáo khoa học

... survivors of childhood acute lymphoblastic leukemia: A report from the childhood cancer survivor study J Clin Oncol 2003, 21:1359-1365 21 Pui CH, Evans WE: Treatment of acute lymphoblastic leukemia ... Survivors of pediatric acute lymphoblastic leukemia (ALL) are at substantially increased risk of developing obesity [3-5] The most common explanations involve late effects of chemo-and radiotherapy, ... reducing the inhibitory effect of the peripheral signal informing of the accumulation of body stores of energy We cannot explain the presence of particular clusters of leptin receptor levels (above...

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báo cáo khoa học: "Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study" doc

Danh mục: Báo cáo khoa học

... Journal of Hematology & Oncology 2008, 1:17 Background Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood Cure of many of these children is difficult ... Study Group for Adult Acute Lymphoblastic Leukemia: Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia Blood 2006, ... childhood acute lymphoblastic leukemia: analysis of patients in continuous complete remission or with consecutive relapse Leukemia 1992, 6:282-288 Potter MN, Steward CG, Oakhill A: The significance of...

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báo cáo khoa học: "Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia" doc

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... NA: Biology and treatment of childhood T-lineage acute lymphoblastic leukemia Blood 1998, 91:735-746 Morris JC, Waldmann TA, Janik JE: Receptor-Directed Therapy of T-Cell Leukemias and Lymphomas ... article as: Huang et al.: Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia Journal of Hematology & Oncology 2010 3:44 ... amounts of the genes of interest and the b2M reference gene were measured in two independent assays The 2(-ΔΔCT) method was used to present the data of the genes of interest Huang et al Journal of...

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Báo cáo y học: "Monoclonal Antibodies against Nucleophosmin Mutants: Potentials for the Detection of Acute Myeloid Leukemia" ppt

Danh mục: Báo cáo khoa học

... the course of dis- 17 18 19 20 21 22 23 24 25 26 27 ease in patients with acute myeloid leukemia Haematologica 2007; 92:1268-9 Falini B, Martelli MP, Bolli N, et al Acute myeloid leukemia with ... Cytoplasmic localization of nucleophosmin in bone marrow blasts of acute myeloid leukemia patients is not completely concordant with NPM1 mutation and is not predictive of prognosis Cancer 2009; ... and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML) Blood 2006; 107: 4011-20 Falini B, Sportoletti P, Martelli MP Acute myeloid leukemia with mutated...

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Báo cáo y học: "Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications" pps

Danh mục: Báo cáo khoa học

... Tandem duplication of the FLT3 gene in acute lymphoblastic leukemia: a marker for the monitoring of minimal residual disease Leukemia 2000, 14:522-524 Xu B, Tian H, Zhou SY: Detection of FLT3 gene ... function of C/EBPa through phosphorylation of the N-terminal serine 21 of this protein by activation of ERK [56] Following this aberrant phosphorylation of C/EBPa, the differentiation of FLT3-ITD ... study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease Blood 2005, 105:986-993 Page of 10...

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báo cáo khoa học: "SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines" ppsx

Danh mục: Báo cáo khoa học

... translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia Genes Chromosomes ... reported in a single case of acute myeloid leukemia (AML) [5] SETNUP214 positive T-ALL patients exhibited high expression levels of HOXA cluster genes [4] Downregulation of the fusion gene repressed ... Grosveld GC: SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoetic progenitors and hyperproliferation of stomach mucosa in transgenic mice...

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báo cáo khoa học: "Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report" docx

Danh mục: Báo cáo khoa học

... suppression of the formation of IgM in B cells, the formation of matrix metalloproteinase-3, and the differentiation of osteoclasts [9,10] The bone marrow karyotyping revealed an abnormal karyotype of ... reported case of co-existing AML-MLD and EBV-associated T-LPD in RA It is possible that the development of AML was secondary Page of (page number not for citation purposes) Journal of Hematology ... the best of our knowledge, this is the first reported case of co-existing AML-MLD and EBV-associated T-LPD in a patient with RA Page of (page number not for citation purposes) Journal of Hematology...

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Báo cáo y học: " Precursor B-cell acute lymphoblastic leukemia presenting as obstructive jaundice: a case report" pdf

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... mass: a rare presentation of acute lymphoblastic leukaemia in an adult JOP 2010, 11:72-74 Takamatsu T: Preferential infiltration of liver sinusoids in acute lymphoblastic leukemia Rinsho Ketsueki ... precursor B-cell acute lymphoblastic leukemia Page of major contributor to the Discussion section NA was involved in the patient’s care (as an oncology fellow) and supervised the drafting of the manuscript ... examinations of the liver specimens in an autopsy series revealed that 44% of untreated patients with leukemias and lymphomas and 26% of the specimens from patients who received chemotherapy either...

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Báo cáo y học: "Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report." doc

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... mutagenic risk potential for development of myeloid leukemia, but not for lymphoblastic leukemia TMZ is a new alkylating agent; its safety profile and lack of data on any mutagenic potential has ... to be augmented in the concurrent presence of radiation, so the proof of efficacy and superiority of TMZ has led to a paradigm shift in the management of aggressive CNS gliomas [1] Although the ... Eisenhauer E, Mirimanoff RO, European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group: Radiotherapy plus...

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Báo cáo y học: "Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report" potx

Danh mục: Báo cáo khoa học

... mutagenic risk potential for development of myeloid leukemia, but not for lymphoblastic leukemia TMZ is a new alkylating agent; its safety profile and lack of data on any mutagenic potential has ... to be augmented in the concurrent presence of radiation, so the proof of efficacy and superiority of TMZ has led to a paradigm shift in the management of aggressive CNS gliomas [1] Although the ... Eisenhauer E, Mirimanoff RO, European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group: Radiotherapy plus...

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Báo cáo y học: "Acute disseminated encephalomyelitis mimicking late CNS relapse of acute lymphoblastic leukaemia: case report" pdf

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... features of a severe acute encephalomyelopathy We made the diagnosis of ADEM based on her MR imaging and exclusion of competing diagnoses Being a diagnosis of exclusion, a discussion of ADEM entails ... pending the results of virology investigations The combination of MR imaging appearances and exclusion of other diagnoses led to the diagnosis of ADEM [2] The classical lesions of ADEM on MRI are ... M, Mikaeloff Y: What is acute disseminated encephalomyelitis (ADEM)? Eur J Paediatr Neurol 2004, 8(5):239-242 Au WY, Lie AK, Liang R, Kwong YL: Isolated extramedullary relapse of acute lymphoblastic...

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Báo cáo y học: "Cost of acute renal replacement therapy in the intensive care unit: results from The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Study" pps

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... source of costs differences between CRRT and IRRT came from the use of anticoagulation In Page of 10 Japan, the cost of anticoagulation is an important part of the total cost of RRT: nearly 50% of ... cost of CRRT and the minimum anticoagulant cost of IRRT, and between the maximum anticoagulant cost of IRRT and minimum anticoagulant cost of CRRT The box represents the 1st and 3rd quartiles of ... Board of the University of Pittsburgh as well as by the Ethics Committees or Investigational Review Boards of each participating site Because of the anonymous and noninterventional nature of the...

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Role of misfolded nuclear receptor co repressor (n cor) induced transcriptional de regulation in the pathogenesis of acute monocytic leukemia (AML m5

Danh mục: Y - Dược

... monocytic leukemia 6) Acute erythroid leukemia (erythroid/myeloid and pure erythroleukemia) 7) Acute megakaryoblastic leukemia 8) Acute basophilic leukemia 9) Acute panmyelosis with myelofibrosis ... myeloid leukemia, minimally differentiated 2) Acute myeloid leukemia without maturation 3) Acute myeloid leukemia with maturation 4) Acute myelomonocytic leukemia 5) Acute monoblastic /acute monocytic ... 2011 TABLE OF CONTENTS SUMMARY i LIST OF PUBLICATIONS iii LIST OF TABLES iv LIST OF FIGURES vi LIST OF ABBREVIATIONS xii CHAPTER INTRODUCTION Introduction 1.1 Acute Myeloid Leukemia 1.1.1 Acute Monoblastic/Monocytic...

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Relapse prediction in childhood acute lymphoblastic leukemia by time series gene expression profiling

Danh mục: Cao đẳng - Đại học

... tool in leukemia diagnosis The diagnosis of leukemia refers to 1) the confirmation of a leukemia case, and 2) the identification of the subtype of a leukemia case A recent study, consisting of over ... samples of MILE-AML and MILE-NBM, respectively The GSS of relapses are shown in the figure 96 x LIST OF ABBREVIATION ALL Acute Lymphoblastic Leukemia AML Acute Myeloid Leukemia ... acute lymphoblastic leukemia (ALL) is the most common type of cancer in children Contemporary management of patients with childhood ALL is based on the concept of tailoring the intensity of therapy...

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