... smokers with COPD, 2) Former smokers with COPD, 3) Current smokers with no evidence ofCOPD or airflow obstruction, and 4) Lifetime non-smokers with no evidence ofCOPD or airflow obstruction Groups ... and serum in patientswithstableCOPD compared to controls Methods Study subjects We recruited categories of subjects aged 35 years or older into this study; 1) Current smokers with COPD, 2) Former ... http://respiratory-research.com/content/11/1/41 mediators vary widely within stableCOPDpatients over time Without knowledge of the inherent variability of the factor being analyzed, it is difficult to know...
... 42 ANNEXES 43 MANAGEMENTofpatientswith dementia 44 ANNEXES 45 MANAGEMENTofpatientswith dementia 46 ANNEXES 47 MANAGEMENTofpatientswith dementia Annex Short form of the Informant Questionnaire ... than in people with Alzheimer’s disease MANAGEMENTofpatientswith dementia Dementia with Lewy bodies Characteristic features of dementia with Lewy bodies (DLB) are fluctuation of awareness ... limited number of behavioural problems in patientswith mild to moderate dementia.97,98,101-105 1++ 1+ One small study of augmentation of perphenazine in patientswith moderate dementia, with either...
... 1994; Moffatt et al 1994; Simon et al 1994) Strength of evidence IAssessment ofPatientswith Leg Ulcers The managementofpatientswith venous leg ulcers Assessment 2.1 Assessment ofPatientswith ... also fall with age Strength of evidence II 10 The managementofpatientswith venous leg ulcers Assessment 2.2 ManagementofPatientswith Venous Leg Ulcers The records show that patientswith venous ... photocopy of each form before sending it 24 The managementofpatientswith venous leg ulcers Appendix 2: Audit Form The managementofpatientswith venous leg ulcers Notes 25 26 The managementof patients...
... the early managementofpatientswith a head injury,14 followed in 1999 by the Galasko report from the Royal College of Surgeons.15 SIGN published SIGN 46: Early managementofpatientswith a head ... half of those attending are children under the age of 14 years The majority ofpatients are fully conscious (see Table 1), without a history of loss of consciousness or amnesia or other signs of ... Intercollegiate Guidelines Network Early managementofpatientswith a head injury A national clinical guideline May 2009 Early managementofpatientswith a head injury ISBN 978 905813 46 Published...
... SIGN 119 Managementofpatientswith stroke: identification and managementof dysphagia6 and SIGN 108 Managementofpatientswith stroke or TIA: assessment, investigation, immediate management ... stroke patients and their families and liaised with services with the aim of improving aspects of participation and quality of life for patientswith stroke and/or their carers The backgrounds of ... an update of SIGN 64 Managementofpatientswith stroke: rehabilitation, prevention and managementof complications, and discharge planning and supersedes it Since the publication of SIGN 64...
... as offering the best compromise between accuracy of staging and containment of morbidity 17 MANAGEMENTOFPATIENTSWITH LUNG CANCER 6.2.5 RESECTION IN PATIENTSWITH STAGE IIIA NSCLC A number of ... for patientswith stage 1A lung cancer and 38-65% for patientswith stage 1B lung cancer Surgery gives the highest chance of cure for patientswith stage I and II lung cancer D 6.2.2 Patientswith ... palliative radiotherapy with single fractions of 8Gy 23 MANAGEMENTOFPATIENTSWITH LUNG CANCER Chemotherapy The greatest change in the managementof lung cancer since the publication of the original...
... days of drug dispensed based on the assessment schedule Patientswith values between 80% and 100% were considered to be treatment compliant Of the 153 patients enrolled in the study, 106 patients ... mg/day Of the 153 patients enrolled in the study, 106 patients (69.2%) were compliant with treatment During the 12-week switching period, no patients received diphenhydramine and five patients ... demonstrated the effectiveness of aripiprazole compared with standard -of- care treatment in outpatient-treated patientswith schizophrenia, especially in the areas of symptom improvement, clinical...
... and exercise in the managementof CVD risk factors in patientswith SMI by evaluating a selective review of relevant literature focusing on the vulnerability ofpatientswith SMI to these risk ... in patientswith SMI were also evaluated, along with current Page of 10 evidence on how improvements in the managementof the CVD risk factors may impact SMI patients mortality and quality of ... in individuals with SMI in the community, 29% of men and almost 60% of women with SMI were obese [51] The prevalence of obesity in patientswith SMI is equal or higher than that of the general...
... impact of non-operative managementof advanced CRC in an unselected, consecutive series ofpatients presenting with newly diagnosed disease It reviews and compares the outcomes ofpatientswith ... formation in patients presenting with malignant large bowel obstruction One of the concerns in managing patientswith surgically incurable CRC without resection of the primary tumour is the risk of the ... score of operated patients, stoma rates in operated patients and the indications for surgery in emergency patientsPatients deemed surgically incurable at presentation were studied Patients with...
... Effect of prone positioning on the survival ofpatientswith acute respiratory failure N Engl J Med 2001, 345:568-573 The ARDS Network: Ventilation with lower tidal volumes as compared with traditional ... 40–49 31–40 0–31 Quartiles of SAPS II Proning may benefit the most seriously ill subset ofpatientswith acute respiratory distress syndrome Those in the quartile with the highest Simplified ... that withholding the option to prone was unethical, based on their early experience Thirdly, a post hoc analysis of the data indicated a marked mortality benefit with proning in the subset of patients...
... led to a relative risk reduction of almost 30% in patientswith septic shock [9] The survival benefit of combination therapy was significant only in patientswith blunted response to ACTH stimulation ... effects of catecholamine dysfunction and refractory hypotension [5] Downregulation of catecholamine receptors occurs with prolonged use of exogenous catecholamines and this may be reversed with ... similar resistance because of poor experiences with identical drugs given in higher doses [18] Levels of cortisol and responsiveness to ACTH stimulation in patientswith sepsis vary considerably...
... the rate of infection of pancreatic necrosis [4] Pooling of the data from these 183 patients by Bosscha and colleagues in a meta-analysis resulted in a group of 95 patients treated with prophylactic ... to acute pancreatitis Con: No, antibiotics are not important in the managementofpatientswith pancreatitis with evidence of pancreatic necrosis Lorne H Blackbourne and Stephen M Cohn Limiting ... mortality (64%) compared with those patients without Candida (19%, P < 0.01) Certainly, critically ill patients developing superinfections tend to be those with more severe disease, with longer antibiotic...
... mind that most patientswith acute respiratory distress syndrome still die of multiple organ failure and not of hypoxemia In this regard, PPV is now used (and normalized by the use of fluid) routinely ... outcome ofpatients undergoing high-risk surgery PPV as a tool to track changes in contractility? Determinants of pulse pressure variation Pulse pressure variation (PPV) is a marker of the position ... Michard et al Figure Patients who have reached the plateau of the Frank–Starling relationship can be identified as patients in whom PPV is low The clinical and intraoperative goal of ‘maximizing stroke...
... classification [13]: Patientswith a forced expiratory volume in sec (FEV1) of 30-50% of their predicted value were categorized into stage III, patientswith a FEV1 below 30% predicted, or with 30-50% ... [Cost -of- illness Study for the Treatment ofCOPD in Germany] Pneumologie 2004, 58:837-844 Rutten-van Molken MP, Oostenbrink JB, Tashkin DP, Burkhart D, Monz BU: Does quality of life ofCOPDpatients ... the assumption of a normal distribution was rejected, and conclusions were compared with those based on the parametric regression models Results Patients A total of 117 patientswith GOLD stages...
... and all patients gave written informed consent All OA patients fulfilled the criteria of the American College of Rheumatology for the classification of OA [24] Isolation and culture of synovial ... 23/53 OA patients DREAM mRNA was significantly reduced by 63% in PBMCs from OA patients, with a pain score on the VAS (0 to 100) of greater than 40 (n = 14) compared with healthy controls OA patients ... compared with healthy controls (❍) and with OA patientswith a low pain score (VAS score of less than or equal to 40; ∇) No significant differences were observed between healthy controls and OA patients...
... to determine the effects of these drugs on total mortality in COPD, we performed a systematic review and meta-analysis with and without TORCH for ICS/LABA and inclusive of UPLIFT for tiotropium ... high-quality randomized controlled trials of tiotropium, formoterol, salmeterol, formoterol/budesonide or salmeterol/fluticasone in patientswithstableCOPD in which total mortality was reported ... years of age), had follow-up of months or greater, and were published in the English language with a Jadad score of or greater [10] We restricted the duration to months to ensure that patients...
... profile of roflumilast Discussion PDE4 inhibitors have demonstrated an anti-inflammatory effect in animal models and patientswithCOPD [6,7] In two previous 12-month studies, in patientswith ... reduction in exacerbations with roflumilast treatment and identified a subgroup ofpatients who are most likely to benefit from treatment with roflumilast, namely those patientswith chronic bronchitis ... stated * Patients could have received more than one of these medications seen for post-bronchodilator FEV1 (see Additional file 1, Table S1) In the group ofpatientswithCOPD associated with chronic...
... will perform a selective review of the psychotropic medications often prescribed to patientswith bipolar disorder, with an emphasis on their use in patientswith medical comorbidity Currently, ... patientswith uncontrolled cancer pain associated with cognitive impairment or anxiety [83] Conclusions The treatment of bipolar disorder is complicated in patientswith medical comorbidity Patients ... treatment with valproate as compared to antidepressants, lithium or gabapentin in patientswith HCV [55] These findings suggest that valproate can be used for some patientswith HCV without adversely...
... treatment with large doses or in the treatment ofpatientswith spasticity of cerebral origin and of the elderly (Aisen et al., 1993) These adverse effects rarely require withdrawal of medication ... 29: 197–202 Pharmacological managementof spasticity Ketel, W B & Kolb, M E (1984) Long-term treatment with dantrolene sodium of stroke patientswith spasticity limiting the return of function ... improvement of mobility and activities of daily living (From & Heltberg, 1975) In a double-blind crossover trial of baclofen and placebo in 23 patients (18 with multiple sclerosis and with spinal...
... American Academy of Neurology: Licensed to the members of the US Headache Consortium PharmacologicalManagementof Acute Attacks A Introduction Effective long-term managementofpatientswith migraine ... Should not be used in patientswith risk of ischemic heart disease Associated with low incidence of recurrence Moderate-to-severe headache Treatment option for patientswith nausea and/or vomiting ... including an improved likelihood of compliance Such a formal plan of care empowers patients to manage their condition with the potential to reduce the number of office and emergency visits The...