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perspectives on the execution of mary queen of scots

Charity Law & Social Policy National and International Perspectives on the Functions of the Law Relating to Charities pptx

Charity Law & Social Policy National and International Perspectives on the Functions of the Law Relating to Charities pptx

Cao đẳng - Đại học

... terms of the donor’s gift. The duty resting on trustees to honour the terms of their trust and ensure that the objects of the charity prevail has always been seen as the primary means whereby the ... presumption that public benefit provision is wholly the responsibility of government has long gone.Government Policy The steady contraction of State responsibility for provision or delivery of public ... such missionary bodies should have the advancement of religion as their primary purpose.95Leaders of Voluntary ActionBy the end of the 19th century charities were the primary providers of health,...
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Báo cáo

Báo cáo " Study on the characteristics and catalytic properties of Pt/SBA-15 in the selective oxidation of D-Glucose " potx

Báo cáo khoa học

... image of the products of D-glucose oxidation on PS-1 catalyst On the other hand, the reaction on Pt/SBA-15 catalysts with pH control not only showed a high conversion, but also high D-gluconic ... 183-190 189- From the results above, we found that both HNO3 and Pt/SBA-15 present a good conversion in the oxidation reaction of glucose. The conversion of the reaction reached 87.67% when ... of plantinum nanoparticles in the selective oxidation of glucose. When the reaction was performed without pH control on PS-1 catalyst, the conversion decreased significantly. The pH at the...
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Báo cáo khoa học: Retrocyclin RC-101 overcomes cationic mutations on the heptad repeat 2 region of HIV-1 gp41 ppt

Báo cáo khoa học: Retrocyclin RC-101 overcomes cationic mutations on the heptad repeat 2 region of HIV-1 gp41 ppt

Báo cáo khoa học

... coincide with the region that binds HR1 upon 6HB formation. The strong affinity of RC-101 for HR2 prevents the inter-action of HR1 and HR2, formation of the 6HB, andsubsequent fusion of the host ... regions of gp41 [12]. During 100 days of serial passaging, HIV-1strain BaL developed three cationic mutations in the presence of sublethal concentrations of RC-101 [14]. Of the three mutations, ... thus the dependence of viral replication on the presence of RC-101 is not surprising. The cationic mutations andloss of glycosylated residues suggest an attempt by the virus to repel the cationic...
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Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

Báo cáo khoa học

... substitutions imposed on the backbone conformation of WT* shows that the pattern of P37P38P19W45Fig. 1. Ribbon structure modelled on the X-ray structure of humanubiquitin [32]. The position and ... solution of native protein wasunfolded by a 1 : 10 dilution to yield final concentrations of GdmCl near or above the midpoint of the equilibriumunfolding transition (concentrations of GdmCl in the range ... that the reduction in stability of thesemutants is largely manifested in perturbations to the unfolding rates with the degree of compactness of the TSE (aD) and linearity of the chevron plots...
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Báo cáo khoa học: Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae potx

Báo cáo khoa học: Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae potx

Báo cáo khoa học

... study, the effect of NaCl concentration on the kinetic constants and thermodynamic stability of VsEndA and VcEndA was investigated. In addition, the effects of reciprocal mutations of two non-con-served ... boundary conditions,and the resulting grid was adopted as the boundary condi-tion for one further focused calculation. The protein mole-cules occupied 90% of the box in the final calculations. The molecular ... activity conditions of the native enzymes [11]. The denaturation peaks weresymmetrical, except for some exothermic distortion of the thermograms after the denaturation peak,especially in the VcEndA...
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Báo cáo khoa học: Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4¢-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein docx

Báo cáo khoa học: Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4¢-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein docx

Báo cáo khoa học

... iden-tified as the major and the minor forms of the holo-ACP structure, on the basis of their percentage contri-butions (65% and 35%, respectively) to the overallstructure of the protein. The structures ... against the fraction number (AU, arbitrary unit). (d) The apparent molecular masses of apo-ACP and holo-ACP were estimated on the basis of the linear regression of the fraction number of the molecular ... elucidates the interactions respon-sible for the conformational stability of PfACP. The size exclusion chromatography profile of PfACPshowed that the apparent molecular mass of PfACPmonomer is...
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Báo cáo khoa học: Effects of cardiomyopathic mutations on the biochemical and biophysical properties of the human a-tropomyosin docx

Báo cáo khoa học: Effects of cardiomyopathic mutations on the biochemical and biophysical properties of the human a-tropomyosin docx

Báo cáo khoa học

... assayed by varying the concen-tration of Tm in the presence of constant concentration of F-actin and myosin S1. In this condition, Tm inh ibits the ATPase activity as its concentration increases [33]. ... stability of the protein as a whole, ratherthan on the position of the mutation in the polypeptide chain,as demonstrated by the biophysical assays. Our studies h aveprovided additional contributions ... f the mutant Tms. The mutations d id not affect the structure of the proteinas there was no significant alteration in the f unction or in the amount of th e s econdary s tructure. However, the...
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influence of binders on the sensing and electrical characteristics of wo3-based gas sensors

influence of binders on the sensing and electrical characteristics of wo3-based gas sensors

Vật lý

... semiconductor, electron transfer occursbetween the semiconductor and the adsorbates. If the electron affinity of the adsorbates is larger than the workfunction of the n-type semiconductor, the ... characteristics of WO film mostly through the chemi-3cal nature of GB rather than the modification of physicalproperties of polycrystals.5. Conclusion The origin of binder effects on the sensing ... than the exponential one since the desorption effect adds on the exponential temperature de-Ž.pendence given by Eq. 5 . But the decrease of filmresistance is faster than the exponential one only...
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Báo cáo

Báo cáo "Effects of Zn content on the magnetic and magnetocaloric properties of Ni-Zn ferrites " pdf

Báo cáo khoa học

... lattice constant and volume of unit cell increase with Zn content in the samples due to larger ionic radius of Zn2+ ion (0.82 Å) substituted for Ni2+ ion (0.78 Å). The X-ray density, the real ... Exchange interactions between magnetic ions through oxygen ion are superexchange interaction with antiferromagnetic nature. These interactions depend on bond distance and bond length. Normally ... each other below the freezing temperature Tf indicating the onset of blocking of clusters. The sample settles into the frozen state below temperature Tf. This behavior is attributed to the...
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Báo cáo khoa học: The ‘pair of sugar tongs’ site on the non-catalytic domain C of barley a-amylase participates in substrate binding and activity potx

Báo cáo khoa học: The ‘pair of sugar tongs’ site on the non-catalytic domain C of barley a-amylase participates in substrate binding and activity potx

Báo cáo khoa học

... with the reduced DMA of the AMY1 Y380A ‘sugar tongs’mutant, these effects may stem from allosteric regula-tion. The mutational analysis of the ‘sugar tongs’ in barleyAMY1 explored the role of ... Thisis the first demonstration of a function for a C domainfrom the large GH clan-H. The work contributes to the unraveling of the molecular basis of multivalentenzyme–polysaccharide interactions. ... connects b5 and a5 of the catalytic (b ⁄ a)8-barrelat the end of the aglycon-binding area of the active sitecleft. Earlier, significant deviation was found in thisregion between the backbone...
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Báo cáo khoa học: Salicylic acid and the hypersensitive response initiate distinct signal transduction pathways in tobacco that converge on the as-1-like element of the PR-1a promoter pot

Báo cáo khoa học: Salicylic acid and the hypersensitive response initiate distinct signal transduction pathways in tobacco that converge on the as-1-like element of the PR-1a promoter pot

Báo cáo khoa học

... host response depending on the genetic constitution of the plant and the pathogen. In an incompatible inter-action, the pathogen remains localized at the primaryinfection sites that often are ... zone 1 (lanes 1,3,5,7) included necrotictissue from the lesions, whereas leaf material of zone 2 was collected ina region 7–14 mm away from the center of the lesions. Due to the expansion of ... collected from a narrowzone including the lesion and from a more distant zonearound single lesions of each plant. Whereas samples from the distant zone of control plants never contained necroticleaf...
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THE EXPOSURE OF YOUTH TO UNWANTED SEXUAL MATERIAL ON THE INTERNET: A National Survey of Risk, Impact, and Prevention pdf

THE EXPOSURE OF YOUTH TO UNWANTED SEXUAL MATERIAL ON THE INTERNET: A National Survey of Risk, Impact, and Prevention pdf

Quản trị mạng

... supportive of different contentions about harm, depending on the emphasis one chooses to give them. On one hand, it is clearfrom their reactions that the majority of youth regard their personalunwanted ... toconfirm a causal relationship.) On the other hand, one of the cautionary findings is that despite itsability to decrease exposure, the software seems far from foolproof.At least 18% of the ... av-erage of 24% of the health information and 91% of the pornography.Although such studies show possible weaknesses in the software ap-proach, they do not address the question of how the programs...
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Báo cáo khoa học: Effects of sphingomyelin, cholesterol and zinc ions on the binding, insertion and aggregation of the amyloid Ab1)40 peptide in solid-supported lipid bilayers ppt

Báo cáo khoa học: Effects of sphingomyelin, cholesterol and zinc ions on the binding, insertion and aggregation of the amyloid Ab1)40 peptide in solid-supported lipid bilayers ppt

Báo cáo khoa học

... obtained for the bilayerin the presence of 1 mM Zn ions, as a function of time, after the addition of A b (5 lM bulk concentration in the sample cell). Initial bindingoccurred mainly in the SM-rich ... facilitate peptide penetration of the hydrocarbon core of the membrane and subse-quent aggregation [22,37]. In order to test the effect of zinc addition in the present experiments on peptidebinding ... without loss of bilayer integrity. A structural interpretation of peptide interaction with the bilayer is presented based on the results of simulation analysis of the PWR spectra.AbbreviationsAb,...
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Báo cáo khoa học: Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4 doc

Báo cáo khoa học: Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4 doc

Báo cáo khoa học

... of the peptide seemsto contribute to the effective anchoring of the tryptophanresidue.Concluding remarks The C-terminal 14 residue truncation of GGN4 abolished the biological activity of the ... tryptophanyl substitution at position 16 on the biological activity was confirmed for the native GGN4.Consistent with the results of the C-terminally truncatedGGN4, the D16W substitution in the native GGN4 ... amphiphilic in nature. The tryptophan side chain conformation was more clearlydefined in both of the environments than those of the other residues (Fig. 2D). However, the orientation of the tryptophan...
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