... subjects who gained weight during the study, insulin resistance increased suggesting that changes in insulin sensitivity induced by CPAP in this setting are mainly determined by changes in body weight ... http://respiratory-research.com/content/12/1/80 in its regulation including changes in insulin sensitivity Insulin administration has been shown to suppress circulating ghrelin levels in some [31] but not all studies [32] Plasma insulin ... levels and insulin resistance correlate inversely with ghrelin This association was BMIindependent in some studies [33] However in a study using euglycemic hyperinsulinemic clamp method, insulin sensitivity...
... Sleep Medicine Task Force: Sleep- Related Breathing Disorders in Adults: Recommendations for Syndrome Definition and Measurement Techniques in Clinical Research Sleep 1999, 22:667-689 Guilleminault ... Guilleminault C: Sleep and breathing In Sleeping and waking disorders: indications and techniques Edited by: Guilleminault C MenloPark, CA: Addison-Wesley Publishing; 1982:155-182 Guilleminault C, Stoohs ... daytime sleepiness: the upper airway resistance syndrome Chest 1993, 104:781-787 Tan WC, Koh TH: Evaluation of obstructivesleep apnoea in Singapore using computerised polygraphic monitoring Ann...
... patients resulting in the rise of plasma norepinephrine and epinephrine levels [25-27] may perhaps be responsible in the insignificant changes between evening and morning blood LBCL in OSAS patients ... BMI – body mass index; NC – neck circumference; ESS – Epworth sleepiness score; TST – total sleep time; AHI (apnea/ hypopnea index) – the number of apneas and hypopneas per hour of sleep; ODI (oxygen ... as a decrease in circulating catecholamines by 20% [26] Catecholamines in vitro, especially epinephrine at physiologic levels revealed concentration dependent inhibition of fMLP-induced degranulation...
... 0.08 0.28 Therapy in patients with OSA, indicating a causative role of OSA in the inflammatory process Since inflammation might play a central role in renarrowing of the vessels in OSA patients, ... Martin; 1997:215-232 Yumino D, Tsurumi Y, Takagi A, Suzuki K, Kasanuki H: Impact of obstructivesleepapnea on clinical and angiographic outcomes following percutaneous coronary intervention in ... difference in left ventricular systolic function (Ejection fraction (66 ± 12% vs 64 ± 16%)) Normal Obstructivesleepapnea Figure effective1CPAP in patients without obstructivesleep apnea, OSA...
... III Modified portable sleepapnea testing Minimum of 7, including EEG, EOG, chin EMG, ECG or heart rate, airflow, respiratory effort, oxygen saturation Minimum of 4, including ventilation (at least ... is clinically measured by the ApneaHypopnea Index (AHI), which is defined as the number of respiratory events per sleeping hour Respiratory events consist of two types: apnea event and hypopnea ... be capable of predicting OSA These questionnaires collect diagnostic information including age, gender, the occurrence and frequnency of waking up in the night, sleepiness in the daytime etc.,...
... usually divide sleepapnea into three major categories: obstructive, central, and mixed apneaObstructivesleepapnea is characterized by intermittent pauses in breathing during sleep caused by ... done according to signals which lie mostly within their correct class OBSTRUCTIVESLEEPAPNEA DETECTION As discussed in the introduction, obstructivesleepapnea (OSA) is a common sleep disorder ... an interest in using overnight ECG recordings from Holter monitors to screen for osbtructive sleepapnea [12] The possibility of screening for OSA using ECG is based on (a) the known changes in...
... (PSG) findings confirm the patients' complaints of insomnia, notably difficulties falling asleep (PSG: increase insleep latency), frequent awakenings during the night and early morning awakenings ... symptoms insleep apnea- hypopneasyndrome Can J Psychiatry 2003, 48:318-323 Engleman HM, Kingshott RN, Martin SE, Douglas NJ: Cognitive function in the sleep apnea/ hypopneasyndrome (SAHS) Sleep ... the hypersomnia -sleep apneasyndromeSleep 1980, 3:407-423 Bardwell WA, Moore P, Ancoli-Israel S, Dimsdale JE: Does obstructivesleepapnea confound sleep architecture findings in subjects with...
... of sleep apnea- hypopneasyndromeIn a retrospective study involving 383 patients for suspected sleep apnea- hypopnea syndrome, overnight polysomnography with simultaneous tracheal sound recording ... CLINICAL ISSUES 14 Gender Differences inObstructiveSleepApnea 247 Vidya Krishnan and Nancy A Collop 15 ObstructiveSleepApneain Children 261 Rafael Pelayo and Kasey K Li 16 ObstructiveSleep ... sleepiness as a drive for sleep (6) Sleepiness may occur more often during “passive” conditions, such as watching television or sitting as a passenger in a car; but in its most severe form, sleepiness...
... daytime sleepiness and snoring requires objective measurement of apneas and hypopneas during sleep for confirmation of OSA In general, confirmation involves an overnight sleep study while monitoring ... subjects to obstructiveapnea Imaging during sleep provides insight into the state-dependent anatomicophysiological changes in the airway Dynamic imaging permits examination of the airway during inspiration ... alternative definition that did not distinguish between an apnea and a hypopnea; the obstructive apnea/ hypopnea event was defined as a reduction in airflow (50% or greater from baseline levels) lasting...
... in remaining awake; slowed down, (6) sleepiness, prefer to be lying down, fighting sleep, woozy, and (7) almost in a reverie, sleep onset soon, lost struggle to remain awake Karolinska Sleepiness ... via inattention, response slowing, or unexpected lapses into sleep Sleepiness is the normal physiological consequence of sleep loss, sleep disruption, or diminished sleep integrity Sleepiness ... Sleep Medicine Sleep 2006; 29(3):381–401 85 Grunstein R Chapter 89 Continuous Positive Airway Pressure Treatment for ObstructiveSleep Apnea- Hypopnea Syndrome, in Principles and Practice of Sleep...
... on sleep quality inobstructivesleepapnea Chest 1999; 116:1545–1549 15 McArdle N, Douglas NJ Effect of continuous positive airway pressure on sleep architecture in the sleep apnea- hypopnea syndrome: ... leptin and vascular risk factors inobstructivesleepapnea Chest 2000; 118:569–571 42 Chin K, Shinizu K, Nakamura T, et al Changes in intra-abdominal visceral fat and serum leptin levels in patients ... Bassiri AG, Guilleminault C Clinical features of evaluation of obstructivesleepapneahypopneasyndrome In: Kryger MH, Roth T, Dement WC, eds Principles and Practices of Sleep Medicine 3rd ed Philadelphia,...
... U.S.A INTRODUCTION Sleep- disordered breathing (SDB) is a collective term, which encompasses snoring, upper airway resistance syndrome (UARS), obstructivesleep apnea- hypopnea syndrome, and obstructive ... four-fold increase in the apnea index and a significant narrowing of the airway at 72 hours following LAUP These findings prompted them to discourage LAUP in patients with moderate or severe sleepapnea ... NB, Riley RW, Robinson A Surgical management of obstructivesleepapneasyndrome Clin Chest Med 1998; 19(1):77–86 38 Riley R, Powell N, Guilleminault C Obstructivesleepapnea syndrome: a review...
... Protriptyline inobstructivesleep apnea: a double-blind trial N Engl J Med 1982; 307(17):1037–1042 91 Guilleminault C, Hayes B Naloxone, theophylline, bromocriptine, and obstructivesleepapnea ... positional sleepapnea can be documented by PSG [including a period of rapid eye movement (REM) sleepin the lateral position] This consists of using methods to prevent individuals from sleeping in the ... that modafinil improves residual daytime sleepiness in patients using CPAP However, it must be stressed that modafinil does not treat sleep apnea, it only treats the symptom of sleepiness In CPAP-treated...
... and obstructivesleepapneahypopnea (OSAH) without daytime sleepiness and obstructivesleepapneahypopneasyndrome (OSAHS) (with daytime sleepiness) To make the issue even more complicated, in ... breathing disturbances in elderly equivalent to sleepapnea syndrome? Sleep 1994; 17:77–83 70 Grunstein R Continuous postivie airway pressure treatment for obstructivesleep apneahypopnea syndrome ... Loughlin GM Inability of clinical history to distinguish primary snoring from obstructivesleepapneasyndromein children Chest 1995; 108(3):610–618 70 Farber JM Clinical practice guideline:...
... Definition and Prevalence of Insomnia Insomnia is defined as a repeated difficulty with initiating sleep, maintaining sleep, a final awakening that occurs much earlier than desired, sleep that is nonrestorative ... similar findings in another study in which 42% of 157 sleepapnea patients had at least one problematic insomnia symptom, with a prevalence of sleep onset insomnia of 6%, sleep maintenance insomnia ... appetitive (feeding or sexual) The movements involved are often explosive or exploratory including kicking, punching, arm flailing, gesturing, shouting, crawling, running, diving from the bed,...
... Potential sleeprelated breathing disorder Obstructivesleep apnea, central sleep apnea, Cheyne-Stokes breathing Central sleepapnea Central sleepapnea Central sleep apnea, obstructivesleepapnea ... symptoms insleepapneahypopneasyndrome Can J Psychiatry 2003; 48(5):318–323 55 Aloia MS, Arnedt JT, Smith L, et al Examining the construct of depression inobstructivesleepapneasyndromeSleep ... to sleep- related breathing is most striking in individuals who have lesions in their central nervous system (CNS) and sleepapnea For some of these individuals, disruption of breathing in sleep...
... imaging, 77–79 Orlistat (Xenical), 236 Orthostatic hypotension UARS, 313 OSA See Obstructivesleepapnea OSAH See Obstructivesleep apnea- hypopnea OSAHS See Obstructivesleep apneahypopnea syndrome ... activities” that appear in the regulations: walking, seeing, hearing, speaking, breathing, learning, and working (84) Interestingly, courts have also ruled that staying awake, in and of itself, is ... upper airway imaging, 75–81 weight gain, weight loss upper airway imaging, 76–77 women, 247–248 Obstructivesleep apnea- hypopnea (OSAH), 305 Obstructivesleep apnea- hypopneasyndrome (OSAHS),...
... improvement in the patient's obstructivesleep apnoea syndrome (apnoea and hypopnoea index at 61.4/h and desaturation index of 42.1/h) A severe condition of obstructivesleep apnoea syndrome was ... of obstructivesleep apnoea syndrome (apnoea and hypopnoea index of 64.9/h with minimum O2 saturation of 29%) The second part allowed a gradual increase in positive pressure, first in continuous ... obstructivesleep apnoea hypopnoea syndromeSleep Med 2003, 4(4):333–338 Competing interests The authors declare that they have no competing interests Authors’ contributions CL analyzed and interpreted...