... infection or trauma that may cause or exacerbate lymphoedema to patients treated for early breast cancer 1.13.3 Ensure that all patientswith early breast cancer who develop lymphoedema have rapid access ... supraclavicular fossa to patientswith early breast cancer and fourormore involved axillary lymph nodes 1.11.13 Offer adjuvant radiotherapy to the supraclavicular fossa to patientswith early breast cancer ... with locally advanced or inflammatory breast cancer who have been treated with chemotherapy 1.13 Complications oflocal treatment and menopausal symptoms Lymphoedema 1.13.1 Inform all patients with...
... studies out ofa total of nine points A score of seven ormore was chosen a priori to indicate high methodological quality Statistical analysis Data were analyzed to yield effect estimates either ... be of lower quality primarily due to a combination ofa lack of biochemical validation of passive smoke exposure, lack of representativeness of the study sample, and /or lack of adjusted analyses ... meta-analyses Additionally, we were inevitably limited in the range of confounding factors that could be adjusted for in our analyses Although the high quality studies generally adjusted for maternal...
... major difference between Braak stage and the NIA-Reagan criteria is that the former only evaluates presence of tau pathology, whereas the latter evaluates presence of both tau and amyloid pathology ... MMP-9/TIMP-1 ratio was increased in AD patients, and correlated with the neuronal degeneration marker tau More importantly, cognitively healthy elderly individuals, with increased riskof developing AD ... summary, our findings suggest that MMPs may be associated with AD pathology as well as with the presence of neuronal degeneration and formation of neurofibrillary tangles already in cognitively...
... Therapeutics (Tsukubu, Japan), and scrambled HO-2 siRNA was used as a negative control: HO-2 siRNA: sense, 5¢-AGGACUUCUUGAAAGGCAA CAUUAAAG-3¢, antisense, 3¢-UAUCCUGAAGAACUU UCCGUUGUAAUU-5¢; scrambled ... Kimpara T, Takeda A, Watanabe K, Itoyama Y, Ikawa S, Watanabe M, Arai H, Sasaki H, Higuchi S, Okita N, et al (1997) Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and ... HO-2 siRNA: sense, 5¢-UAUAAGAGUCAGUACACAUCAUGGAAG-3¢, antisense, 3¢-UAAUAUUCUCAGUCAUGUGUAGUACCU-5¢ Another HO-2-specific siRNA, HO-2 siRNA1 (target base 212–232) reported by other investigators [32],...
... temporarily function as a pro-inflammatory mediator at the early activation stage, and thereafter function in an antiinflammatory role, through the suppression of nitric oxide generation in an autocrine ... spinal cords of rats with EAN We found that some inflammatory cells infiltrated the spinal nerve roots, and subarachnoid space, but only rarely infiltrated the spinal cord parenchyma OPN was expressed ... rat spinal cord in EAN To examine the activation of spinal cord cells in EAN, we performed immunostaining for ED1 and GFAP to identify activated microglia/macrophages and astrocytes In normal...
... primary authors of retrieved studies for additional data and/ or clarification of data, where necessary Study selection and data abstraction The primary objective of this study was to compare ... indicate that smoking may also have a greater (negative) impact on lung growth in female than male youngsters Gold et al [31] found that among adolescents, smoking five ormore cigarettes a day, as ... size, average age at baseline, proportionality of women, duration of follow up, and annual decline rate of FEV1 % pred stratified by gender and smoking status (Table 1, Table 2) Any questions or...
... enzyme immunoassay in a calibrated IMMULITE 1000 analyzer (Diagnostic Products Corporation, Los Angeles, CA, USA) The intra-assay and interassay coefficients of variation at various concentrations ... occurrence of postoperative delirium was assessed with the use of multivariate logistic regression analyses Initially, baseline and perioperative variables were evaluated for univariate association with ... Huth C, Herrmann M: Early neurobehavioral disorders after cardiac surgery: a comparative analysis of coronary artery bypass graft surgery and valve replacement J Cardiothorac Vasc Anesth 2001,...
... with extracorporeal support [9] The prevalence of endotoxemia in patients on cardiopulmonary bypass has been estimated at up to 100% of ACB patients, although estimates are highly variable [8,9] ... stay of 61 days associated with multiple complications There were no statistically significant differences in length of stay for patientswith EAA ≥0.40 versus patientswith EAA < 0.40 at any ... correlations among repeated measures for each patient and for a few missing EAA values, change in EAA levels over time was evaluated using mixed models Factors associated with the prevalence of elevated...
... use of loratadine and hypospadias and the rate of hypospadias among loratadine-exposed infants was highly significantly lower than that during the first period There are two possible explanations ... study [1] was based on prescription data and therefore uncertain exposure information and in spite of its size of 319 hypospadias cases found an adjusted OR for hypospadias after loratadine exposure ... that the earlier observed association between maternal use of loratadine in early pregnancy and birth of infants with hypospadias was the result of multiple testing Acknowledgments The study was...
... nutritional status and potential secondary causes of osteoporosis are to be taken into consideration before the onset of the treatment of HIV-infected patients Abnormal laboratory values of elevated alkaline ... recognized as a stimulator of osteoclastic formation and a promoter of osteoblast differentiation [49] There are also numerous local factors that play an important role in the physiology of bone ... bicarbonate levels, raised alkaline phosphatase level, and lower body weight before antiretroviral therapy There have also been a few case reports of pathologic fractures in AIDS patientswith antiretroviral...
... spectral radius of matrixes to define his results He said that the identifying formulae for αm for m ≥ was a difficult problem, and he only estimated the values of αm for m 10 Now, in this paper, ... Hutchinson, Fractals and self-similarity, Indiana Univ Math J 30 (1981) 713 [4] T Hu, K Lau, Multifractal structure of convolution of the Cantor measure, Adv in Applied Math., (to appear) [5] P Shmerkin, ... Falconer, Fractal Geometry-Mathematical Foundations and Applications (1990), John Wiley & Sons [2] B Jessen, A Wintner, Distribution functions and the Riemann zeta function , Trans Amer Math Soc...
... d s of t a r g e t (113 m s e c for NP-attached targets across the two c o n d i t i o n s of context, and 358 m s e c for the VP-attached targets) Once again, the non-minimally attached t a r ... models More specifically, it is an account based on the act of establishing what is, and w h a t is not, a l r e a d y k n o w n to the hearer But a l t h o u g h it can e x p l a i n p a r s ... safes" to "a safe and a j e w e l r y box" This is a c h a n g e which, in theory, a f f e c t s only the cardinality of the set of "safes" It was 124 found that there was a strong effect of r e...
... energies can be calculated and BCF data can be recalculated at temperatures other than those used for the measurement Advantages of SUMA Unlimited input data possibilities Simple usage WINDOWS compatible, ... Subsite map of barley a- amylase isoenzyme The binding a nities were calculated according to the data of Table Fig Subsite maps for porcine pancreatic a- amylase (PPA) The solid bars are related to ... used for saving, editing and printing calculated data Graphical illustrations (minimization, subsite map) make the results clearer BCFs can be calculated for substrates longer or shorter than those...
... with the catalyst This results in formation of only a few of SiNWs The reaction temperature is usually decided with the consideration of the catalyst type According to the binary phase diagram ... quantity of Si and SiS2 atoms are quickly flowed away by the protected gas to an area with lower temperature (B in Fig 4A) When temperature decreases, the Si atoms are easier to reach saturation ... 2B a) , a liquid metal–Si alloy will be formed Withmore and more Si atoms added, the Si content in the If the growth witha metal catalyst can cause contamination, the synthesis without metal...
... the above, witha restriction that t may start only in a given position in a tag image ofa sentence The basis for the automaton Which checks a tag stream (path) for validity as a tag-image relative ... to assume that a preliminary morphological phase separated word-forms to basic sequences of tags, and then state syntactic rules in terms of standard word classes able for derivations), and a ... permutations This generates a very htrge number of rather random tag images Applying LCA(I), only a small number of hnages are rccogtfizcd as potentially valid Among them are syntactically correct...
... below: aA −→ A −→ A − − a aa , aaA −→ A −→ A − − 1 A −→ A −→ A − − 1 aA − → A − → A − − a Note that both loops are based at the vertex A − A We must show that → a → ... is a homotopy cartesian square of pointed spaces, and there is a canonical contraction of the upper right-hand term 1.4 Let A be an abelian category We view A as a category with cofibrations and ... subcategory of A, and assume that for every exact sequence in A, → A → A → A → 0, if A and A are in E then A is in E, and if A and A are in E then A is in E We then view E as a subcategory with...
... case of ADH1B1 (5¢-CTA TCGGATCCATGGGCACTGTTGGAAAAG-3¢ and 5¢-CCACTTGAATTCTCAAAACGTCAGGACCGT-3¢), for the cloning into pGEX-4T-2 The same mutagenesis protocol as that used to prepare human ADH1B2, ... primers to amplify the full-length cDNA by polymerase chain reaction and introduced restriction sites (underlined) for BamHI at the 5¢ end (5¢-CTAT CGGATCCATGAGCACAGCAGGAAAAG-3¢) and for EcoRI at the ... (5¢-GAATCTGTCACACAGATGACCACGTGG-3¢, amino acid positions 44–52 and 5¢-GTCATCTGTGTGA CAGATTCCTACAGCC-3¢, amino acid positions 42–50) to introduce the mutation R47H by PCR Mutated nucleotides are...