parkinson s disease and other lewy body diseases

Tài liệu THERAPEUTICS of PARKINSON’S DISEASE and OTHER MOVEMENT DISORDERS docx

Ngày tải lên : 14/02/2014, 17:20

... THERAPEUTICS of PARKINSON S DISEASE and OTHER MOVEMENT DISORDERS Therapeutics of Parkinson s Disease and Other Movement Disorders Edited by Mark Hallett and Werner Poewe © 2008 John Wiley & Sons, Ltd ISBN: ... degradation and PARKINSON S DISEASE AND PARKINSONISM PARKINSON S DISESASE Sporadic Autosomal Dominant SYN LRRK2 UCH-L1 GENES TOXIN Autosomal Recessive AGING PARKIN DJ-1 Protein O abnormal autophagy UPS ... McNaught, K .S and Jenner, P (2001) Proteasomal function is impaired in substantia nigra in Parkinson s disease Neuroscience Letters, 297 (3), 191 194 20 PARKINSON S DISEASE AND PARKINSONISM McNaught,...

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Surgical Treatment of Parkinson’s Disease and Other Movement Disorders pot

Ngày tải lên : 05/03/2014, 23:20

... neurons Reports of movement disorders secondary to extrastriatal pathology should therefore come as no surprise 3.1 Parkinson s Disease Early idiopathic Parkinson s disease (PD) is a well-circumscribed ... pathophysiology of common human movement disorders such as Parkinson s and Huntington s diseases (PD/HD) These structures classically include: 1) the striatum, which comprises the caudate nucleus (CD), ... interpretations of the different movement disorders, because of the existence of movement disorders such as Huntington s disease (HD) or dystonia, which seem to cross the boundary between these diseases...

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Tài liệu Parkinson’s Disease and Related Disorders docx

Ngày tải lên : 14/02/2014, 17:20

... L.: Sleep disturbances and excessive daytime sleepiness in Parkinson disease: an overview Arnulf, I.: Sleep and wakefulness disturbances in Parkinson s disease ... Disease and Parkinsonism seen at the Columbia-Presbyterian Medical Center from 1949 to 1964 Nearly 85% had classic Parkinson s Disease and 13% had post-encephalitic associated Parkinsonism This ... congress site and was often seen discussing topics of mutual interest with congress participant s There was an interesting new study presented by Professor Deuschl, Kiel, in which he demonstrates...

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Tài liệu Alzheimer’s Disease and Other Dementias doc

Ngày tải lên : 14/02/2014, 18:20

... Psychological Disorders Alzheimer s Disease and Other Dementias Psychological Disorders Addiction Alzheimer s Disease and Other Dementias Anxiety Disorders Child Abuse and Stress Disorders Depression ... feelings, vision problems, etc Degenerative diseases like Huntington s disease or other rare, usually genetically transmitted diseases may also cause dementia in adolescents This illness destroys ... blood vessels that supply the heart muscle with oxygen and nutrients narrow These diseases can cause strokes and heart disease (heart attacks) in the elderly The most common causes of illness and...

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PARKINSON''''S DISEASE AND MOVEMENT DISORDERS: DIAGNOSIS AND TREATMENT GUIDELINES FOR THE PRACTICING PHYSICIAN potx

Ngày tải lên : 05/03/2014, 23:20

... PARKINSON' S DISEASE AND MOVEMENT DISORDERS: DIAGNOSIS AND TREATMENT GUIDELINES FOR THE PRACTICING PHYSICIAN CURRENT CLINICAL PRACTICE Parkinson s Disease and Movement Disorders: Diagnosis and ... disorders On the island of Guam, amyotrophic lateral sclerosis, parkinsonism, and dementia occur in various combinations, perhaps as manifestations of the same disease process Outside Guam, the association ... paresis, however, has sinister implications; it is typical of certain multisystem cerebral disorders, such as progressive supranuclear palsy, variants of Niemann-Pick disease, and, sometimes,...

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The Handbook of Alzheimer’s Disease and Other Dementias doc

Ngày tải lên : 14/03/2014, 21:20

... Alzheimer s disease and dementia will ﬁnd this book of interest, including physicians, medical students, psychologists, scientists, graduate students, and allied health professionals including nurses, social ... dementias Psychiatric disorders Important examples Prion diseases, syphilis, Lyme disease, chronic meningidites, PML, HIV, Whipple s disease, hydrocephalus Primary or metastatic tumors, (particularly ... infarct dementia “Binswanger s disease “Small vessel ischemic disease CADASIL Schizophrenia Dementia syndrome of depression Bipolar disorder Malingering Obsessive compulsive disorder CCl4 = carbon...

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An Atlas of PARKINSON’S DISEASE AND RELATED DISORDERS pdf

Ngày tải lên : 14/03/2014, 22:20

... index ISBN 1-85070-943-2 Extrapyramidal disorders Atlases Parkinsonism Atlases Movement disorders Atlases I Title II Series [DNLM: Parkinson Disease atlases Basal Ganglia Diseases atlases Movement ... Parkinson s disease ©2004 CRC Press LLC Figure 11 Posture in later-stage Parkinson s disease Figure 12 Parkinson s disease: Impaired fist clenching Figure 13 Parkinson s disease: Tremor illustrated ... characteristics of Parkinson' s disease must take into account the inaccuracies of clinical diagnosis In a successive series of 100 patients with a clinical diagnosis of Parkinson' s disease, only...

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An Illustrated Pocketbook of Parkinson''''s Disease and Related Disorders pot

Ngày tải lên : 14/03/2014, 22:20

... PARKINSON S DISEASE Figure 16 Parkinson s disease: dystonic posturing of the big toe secondary to dopa therapy 15 16 AN ILLUSTRATED POCKETBOOK OF PARKINSON S DISEASE Figure 17 Parkinson s disease: ... Posture in later-stage Parkinson s disease AN ILLUSTRATED POCKETBOOK OF PARKINSON S DISEASE Figure 12 Parkinson s disease: impaired fist clenching 11 12 AN ILLUSTRATED POCKETBOOK OF PARKINSON S ... RD, Bakay RA Neurosurgical horizons in Parkinson s disease Neurology 1993;43:l–7 Parkinson' s disease Any discussion of the clinical characteristics of Parkinson s disease must take into account...

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báo cáo hóa học: " Gait dynamics in mouse models of Parkinson''''s disease and Huntington''''s disease" doc

Ngày tải lên : 19/06/2014, 10:20

... SOD1 G93A and wild-type control mice at age ~8 weeks, ~10 weeks, ~12 weeks, and ~13 weeks Discussion Gait disturbances are characteristic of Parkinson' s disease, Huntington 's disease, and amyotrophic ... image analyses The treadmill belt was wiped clean between studies if necessary Statistics Data are presented as means ± SE ANOVA was used to test for statistical differences among saline-treated, ... in Parkinson' s disease and Huntington 's disease Mov Disord 1998, 13:428-437 Blin O, Ferrandez AM, Serratrice G: Quantitative analysis of gait in Parkinson patients: increased variability of stride...

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PARKINSON’S DISEASE AND RELATED DISORDERS - PART 5 pot

Ngày tải lên : 09/08/2014, 16:21

... Figure 14 Positive glabellar tap Persistent blinking is a feature of Parkinson s disease, but is also seen in Alzheimer s disease Figure 15 6-[18F]-fluorodopa–PET scan appearance in a normal subject ... cells (astrocytes and macrophages) Debris and a few vascular channels can be seen (Luxol fast blue–H & E) Figure 24 CT of a patient with a Parkinsonian syndrome shows multiple lacunar infarcts ... Histological sections from Parkinson' s disease with dementia showing cortical Lewy bodies stained with ubiquitin (immunochemistry preparation, left; silver impregnation, right) Figure 28 Histology...

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PARKINSON’S DISEASE AND RELATED DISORDERS - PART 6 ppt

Ngày tải lên : 09/08/2014, 16:21

... normal subject (left) compared with that in Parkinson' s disease (middle) and in progressive supranuclear palsy (right) (11C-raclopride is a selective reversible antagonist of D2 receptors) Figure ... degeneration shows atrophy of the putamen with rarefaction and gliosis (H & E) Figure 35 Transverse section of midbrain in striatonigral degeneration shows pallor of the substantia nigra ©2004 CRC Press ... (lower) basis pontis secondary to olivopontocerebellar atrophy in multiple system atrophy Figure 38 Histological sections of basis pontis (arrowed) show the normal complement of pontine neurons in...

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PARKINSON’S DISEASE AND RELATED DISORDERS - PART 7 pot

Ngày tải lên : 09/08/2014, 16:21

... 45 Histological section of cerebral cortex in corticobasal degeneration shows severe gliosis and an achromatic neuron (H & E) Figure 46 Histological sections of cerebral cortex showing swollen ... proved responsive to botulinum toxin ©2004 CRC Press LLC Figure 55 Abnormal neck posture in a patient with spasmodic torticollis Figure 56 Mechanisms of actions of various botulinum toxins (BTX) ... copy three hand postures (A–C, lower), in each instance, the patient 's version was defective (A–C, upper) ©2004 CRC Press LLC Figure 50 In this patient with corticobasal degeneration, sagittal T1-weighted...

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PARKINSON’S DISEASE AND RELATED DISORDERS - PART 8 ppt

Ngày tải lên : 09/08/2014, 16:21

... Histology in Wilson 's disease shows atrophy and rarefaction of the putamen (black arrows) Loss of myelin bundles in the putamen contrasts with the more normal appearances in the globus pallidus ... Huntington 's disease is accompanied by DNA gels (lower) which indicate trinucleotide repeats of between 40 and 52 ©2004 CRC Press LLC Figure 68 Coronal section of brain in Huntington 's disease shows symmetrical ... fast blue) Figure 63 Histology of brain in Wilson 's disease shows a Bergmann type astrocyte within an atrophic putamen (H & E) ©2004 CRC Press LLC Figure 64 Histology of brain in Wilson 's disease...

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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx

Ngày tải lên : 18/02/2014, 14:20

... metabolism and that cause diseases in which Lewy bodies are known to be abundant; (b) genes that may be involved in ceramide metabolism and cause diseases in which Lewy bodies have been described; and ... intracellular cholesterol trafﬁcking Transferase activity ATPase Dopamine transmission and synaptic vesicle dynamics Protein kinase Gaucher s disease ⁄ Parkinson s disease in heterozygotes Neurodegeneration ... glycosyltransferase; CK, ceramide kinase; CS, ceramide synthase; DES, desaturase; GALC, galactosylceramidase; GBA, glucosylceramidase; GCS, glucosylceramide synthase; SMS, sphingomyelin synthase;...

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The Use of Selected Medicinal Herbs for Chemoprevention and Treatment of Cancer, Parkinson’s Disease, Heart Disease, and Depression

Ngày tải lên : 25/10/2013, 05:20

... 11.3 Parkinson s Disease Parkinson s disease (also known as Parkinson disease or PD) is a degenerative disorder of the central nervous system that often impairs the sufferer s motor skills and speech ... functions, neurotransmitter levels, emotional stress, and progression of neurodegenerative conditions such as Parkinson s and Alzheimer s diseases (Rahman et al., 2008) 11.4 Heart Disease 11.4.1 Case ... ﬂesh, including essential fatty acids from seeds and seed oils, and ﬁbers, such as microcrystalline cellulose, pectins, lignins, cutin-like polymers, and condensed tannins, have been suggested...

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Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx

Ngày tải lên : 15/02/2014, 01:20

... biology and oxidative stress in Parkinson disease pathogenesis Nat Clin Pract Neurol 4, 600–609 Lesage S & Brice A (2009) Parkinson s disease: from monogenic forms to genetic susceptibility factors ... MF (2007) Parkinson s disease Hum Mol Genet 16 Spec No 2, R183–R194 Devine MJ & Lewis PA (2008) Emerging pathways in genetic Parkinson s disease: tangles, Lewy bodies and LRRK2 FEBS J 275, 5748–5757 ... network, as well as statistically signiﬁcant functional association with GO classiﬁcations [16] Western blotting Expression of a-synuclein and HSP70 was determined by western blotting Proteins (80...

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