oxford bookworms stage 1 sherlock holmes and the sport of kings

Báo cáo khoa học: Sherlock Holmes and the proteome ) a detective story Pier Giorgio Righetti1 and Egisto Boschetti2 potx

Ngày tải lên : 07/03/2014, 10:20

... mechanism is rather delicate (it encompasses all types of bonds 250- 15 0- 10 0- 75- 50- 37- 25- 20- 15 - 10 - M r (kDa) M r (kDa) 3 pI 10 A 250- 15 0- 10 0- 75- 50- 37- 25- 20- 15 - 10 - 3 pI 10 B Fig. 5. ... synthesis of the beads and some of their fundamental properties has recently been published [20], together with reviews describing the basic con- cepts [9, 21, 22]. The mechanism of action of the Equal- izer ... which might bafﬂe even the most famous investigator, Sher- lock Holmes [1] . The reason is that, in any proteome, a few proteins dominate the landscape and often oblit- erate the signal of the rare ones,...

9
666
0

sherlock holmes and the treasure train

Ngày tải lên : 31/05/2014, 01:56

... though the air was crisp and cold. In London, with the moisture of the Thames close-by, I would have thought it raw, but not so in the dry and clear air of the countryside. Leaving the buildings of ... Brent. Considering the speed of the freight and the position of the riflemen guarding it, there was no way the thieves could have gotten on the train save from above." Holmes& apos;s careful ... target and they had to land at just the right spot to shove the smoke bombs into the armored cubicle before the guards recovered their wits and started shooting. They couldn't just jump at the...

118
252
0

Báo cáo khoa học: Carbohydrate binding sites in Candida albicans exo-b-1,3-glucanase and the role of the Phe-Phe ‘clamp’ at the active site entrance ppt

Ngày tải lên : 15/03/2014, 23:20

... 32.65 1. 90 (1. 95 1. 90) 38.23–2.00 (2 .11 –2.00) 19 .85 1. 80 (1. 85 1. 80) 38 .19 1. 70 (1. 79 1. 70) Space group P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 Unit cell parameters a = 60.33 a = 58.57 a = 59.95 ... for angles (deg) 1. 35 1. 46 1. 25 1. 94 r.m.s.d. for chiral volume (A ˚ 3 ) 0.09 0 .11 0.08 0 .14 Number of protein atoms 3 211 3233 3 214 3254 Number of ligand atoms 24 58 Number of water atoms 334 ... respectively (Received 17 August 2 010 , revised 1 September 2 010 , accepted 3 September 2 010 ) doi :10 .11 11/ j .17 42-4658.2 010 .07869.x Candida albicans exo-b -1, 3-glucanase (Exg; EC 3.2 .1. 58) is implicated in cell wall...

13
498
0

Báo cáo hóa học: " A predominance of R5-like HIV genotypes in vaginal secretions is associated with elevated plasma HIV-1 RNA levels and the absence of anti-retroviral therapy" docx

Ngày tải lên : 20/06/2014, 01:20

... variants [9 ,13 ], the low levels of HIV detected in many of the samples only allowed the analysis of the predominant genotypes in genital secretions. Despite this, and the inherent limita- tions of PCR ... drafted the manuscript. PK participated in the study design and con- ducted the statistical analyses. RC participated in the design and coordination of the study and facilitated the collection of ... gel, mobility ratios of the heteroduplexes formed between sample and probe V3 sequences were analyzed and used to determine the predominant genotype of the patient sample, as described [9 ,12 ,13 ]. R5-like...

4
481
0

Tài liệu Golf and the game of leadership 1 pdf

Ngày tải lên : 24/12/2013, 16:15

... Results 15 1 Hole 14 Provide Constructive Feedback 16 2 Hole 15 Accept Change: Adapt 17 5 Hole 16 Caddies, Coaches, and Teams 18 6 Hole 17 An Optimistic Outlook 202 Hole 18 It’s Up to You 212 The 19 th ... day. 10 589$ $$FM 02-23-04 16 :43:59 PS viii Contents Hole ࠼9 Responsibility 10 0 Hole 10 ‘‘Big Bertha’’: Conﬁdence 11 0 Hole 11 Performance Expectations 12 3 Hole 12 Courage 13 5 Hole 13 Recognize ... recording, or otherwise, without the prior written permission of AMACOM, a division of American Management Association, 16 01 Broadway, New York, NY 10 019 . Printing Hole Number 10 9876543 21 10 589$ $$FM...

10
744
0

Tài liệu Báo cáo khoa học: Mutational analysis of plasminogen activator inhibitor-1 Interactions of a-helix F and its neighbouring structural elements regulates the activity and the rate of latency transition pdf

Ngày tải lên : 20/02/2014, 11:20

... ± 13 63 ± 6 M149K 83 ± 11 13 6 ± 24* N152D 99 ± 8 67 ± 3 G155P, K156S, G157E 75 ± 16 50 ± 2* N152D, G155P, K156S, G157E 83 ± 12 67 ± 6 G155K, D (15 6 15 7), A158E 66 ± 12 73 ± 6* M149K, G155K, D (15 6 15 7), ... 61 ± 7 T146A 7 ± 1 217 ± 33* K147A 87 ± 12 26 ± 6* M149A 10 ± 6 18 ± 2* N152A 13 ± 2 17 ± 3 and 11 0 ± 21* a E283A 33 ± 3 14 ± 3* E285A 97 ± 0 79 ± 3* K325A 82 ± 19 10 6 ± 8* K327A 6 ± 0 11 ± 1* PAI -1 stab 69 ... giving indistinguishable results: wild-type, PAI -1( T96A), PAI- 1( F100A), PAI -1( V126A), PAI -1( F128A), PAI -1( I137A), PAI -1( I138A), PAI -1( N139A), PAI -1( W141A), PAI- 1( T146A) and PAI -1( M149K). Structural analysis Structural...

9
605
0

Báo cáo khoa học: Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 – a molecular link between recombination and chromatin assembly during meiosis pot

Ngày tải lên : 07/03/2014, 05:20

... and Lim15/Dmc1 [8]. The heterodimeric complex of Hop2 and Mnd1 stimulates strand exchange of Lim15/Dmc1 [9 11 ]. The meiosis-speciﬁc proteins Mei5 and Sae3 form a complex with Lim15/Dmc1 and are ... recruits the DNA polymerase to the site of Lim15/Dmc1. The broken line represents newly syn- thesized DNA. (C) CAF -1 forms a complex with Lim15/Dmc1 and PCNA. CAF -1 deposits histones H3 and H4 or other ... homolog Dmc1. Cell 11 9, 927– 940. 13 Tsubouchi H & Roeder GS (2004) The budding yeast mei5 and sae3 proteins act together with dmc1 during meiotic recombination. Genetics 16 8, 12 19 12 30. 14 Neyton...

10
487
0

the oxford introduction to proto-indo-european and the proto-indo-european world nov 2006

Ngày tải lên : 11/06/2014, 10:19

... Anatomy 17 3 11 .0 The Body 17 3 11 .1 The Head 17 3 11 .2 Hair 17 6 11 .3 The Upper Body and Arms 17 8 11 .4 The Lower Body and Legs 18 2 11 .5 Internal Organs 18 5 11 .6 Vital Functions 18 8 11 .7 Health and Disease ... and Disease 19 2 11 .8 The Lexicon of the Body 19 9 12 Family and Kinship 203 12 .1 Family and Household 203 12 .2 Marriage 206 12 .3 Kinship 209 13 Hearth and Home 219 13 .1 Dwelling 219 13 .2 Construction ... 1, 339 1, 902 Celtic 687 1, 823 Slavic 1, 1 01 1,429 Iranian 1, 122 1, 408 Tocharian 377 1, 111 Anatolian 1, 3 41 765 Armenian 327 595 Albanian 16 3 445 Other 56 16 7 Total 13 ,369 22,292 Note: Gamkrelidze and...

760
778
0

Báo cáo sinh học: " No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients" pdf

Ngày tải lên : 18/06/2014, 19:20

... 41 35 38 Mucoid + signet ring 20 9 11 9 11 9 11 14 6 11 9 Pathologic Grade 0.799 0.998 0.9 91 0.582 G1 2 1 1 1 1 1 1 0 2 0.0 01 11 G2 69 32 37 34 35 32 37 28 41 32 37 G3 22 12 10 11 11 10 12 18 ... 10 12 18 4 13 9 Growth type 1. 000 0.769 0.239 0.769 Pushing 31 15 16 16 15 17 14 18 13 16 15 Infiltrating 62 30 32 30 32 26 36 28 34 0.2 41 30 32 Invasive depth 0.683 0.293 0.826 0. 615 T3 77 38 ... 0. 911 0.377 0 .12 1 0.4 71 <60 43 18 25 212 2 22 21 2 518 2320 ≥60 50 27 23 25 25 21 29 21 29 23 27 Gender 0.407 0.574 0.726 26 0.250 0.045 Male 58 30 28 30 28 26 32 26 32 24 34 Female 35 15 20 16 19 ...

6
468
0

báo cáo hóa học: " Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes" pdf

Ngày tải lên : 19/06/2014, 22:20

... means). HIF -1 HIF -1 shift 1 2 3 4 5 6 7 8 9 10 11 12 13 14 HIF -1 HIF -1 D +/+ HIF -1 D +/- HIF -1 D +/+ HIF -1 D +/- C H Co C H Co C H Co C H Co H H Wild-type HIF -1 probe Mutant HIF -1 probe Treatment Cells Probe HIF -1 D +/+ wt HIF -1 D antibody -+ A) B) CHCHCH 0 50 10 0 15 0 200 250 300 pGL3 pGL3/MCP1w pGL3/MCP1m * Luciferase ... factor -1 and the regulation of mammalian gene expression. J Exp Biol 19 98, 2 01: 115 3 -11 62. 20. Wenger RH: Mammalian oxygen sensing, signalling and gene regulation. J Exp Biol 2000, 203 :12 53 -12 63. 21. ... DNA binding and activation of HIF -1 target genes [15 ,16 ]. Sev- eral HIF -1 isoforms have been found, including HIF-2α and HIF-3α, both of which have significant homologies to HIF -1 [13 ,14 ,17 ]. Although...