... modifying the definition of central obesity in Asian 68 populations on the association between themetabolicsyndromeand ischemic heart disease 4.2 The role of central obesity in the definition themetabolic ... of obesity in Asian populations 21 1.6 The role of obesity in the pathogensis of insulin resistance andthemetabolic 25 Syndrome 1.7 Obesity as a pre-requisite risk factor for defining themetabolic ... defining themetabolicsyndromeThe literature linking obesity (particularly central obesity) and insulin resistance are so compelling that, in making their recommendations for the diagnosis of the metabolic...
... two of the components of themetabolicsyndrome (high TG and hypertension), but not any of the other components (low HDL, obesity, and glucose intolerance) or the presence of themetabolicsyndrome ... hypertension [11,12], and central obesity [11]: these may collectively contribute to the development of themetabolicsyndrome [13,14] and atherosclerosis [15,16] Themetabolic syndrome, first described ... the draft of the manuscript GDK contributed substantially to the conception and design of the project and to the revision of the draft of the manuscript All authors read and approved the final manuscript...
... two of the components of themetabolicsyndrome (high TG and hypertension), but not any of the other components (low HDL, obesity, and glucose intolerance) or the presence of themetabolicsyndrome ... hypertension [11,12], and central obesity [11]: these may collectively contribute to the development of themetabolicsyndrome [13,14] and atherosclerosis [15,16] Themetabolic syndrome, first described ... the draft of the manuscript GDK contributed substantially to the conception and design of the project and to the revision of the draft of the manuscript All authors read and approved the final manuscript...
... [11]) Mutation in the Clock gene leads to metabolicsyndrome in mice [12], and in humans Clock polymorphisms have been associated with obesityandmetabolicsyndrome [13,14] Cellular metabolic states ... drinking on the same day In the laboratory, a nurse recorded how these instructions had been followed and then took the blood samples The samples were centrifuged at the examination site and placed ... abuse and dependence, and other substance dependence and abuse As part of the assessment, the participants filled in the items of lifetime seasonal variations in mood and behavior taken and adapted...
... adipose tissue in obesityand related insulin resistance [15] Here, we focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesityand related metabolic diseases, and discuss whether these ANGPTLs ... etc) Induction Fig Schematic diagram showing the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesityand related metabolic diseases The expression of ANGPTL2 and ANGPTL6 ⁄ AGF is induced in obese conditions ... treatments for obesityandmetabolic diseases associated with chronic inflammation (Fig 1) Activation of ANGPTL6 ⁄ AGF counteracts obesityand related metabolic diseases ANGPTL6 ⁄ AGF, the angiopoietin-like...
... contributors to the development of central obesityandthemetabolicsyndrome [2,18] The risk of developing all other components of themetabolicsyndrome increases with obesity, supporting the hypothesis ... between obesityandthe development of cardiovascular disease [21,22] Despite the pivotal role of obesityand dyslipidemia in the development of themetabolicsyndromeand heart disease, the functional ... appetite and may function as the link between obesityand hypertension in individuals with themetabolicsyndrome [39,40] To determine whether theobesity observed in ApoE3knock-in and C57BL/6...
... andand the presence ofmetabolic syndrome according to the definition used used * P < 0.05 EGIR The relationship between methotrexate use the presence of thethemetabolicsyndrome according to the ... patients The prevalence of the MetS increased with age up until the seventh decade and fell off thereafter, and was similar in males and females (P = 0.429; Table 3) Associations of themetabolicsyndrome ... drafted the manuscript KMD acquired the data GDK made substantial contributions to the conception and design of the study and revised the draft manuscript All authors read and approved the final...
... definitions from themetabolicsyndromeThe previous work evaluated this difference and did not analyze the relative weight of each component of themetabolicsyndromeThe importance of the current ... OR and AS have participated in the design of the study, performed the statistical analyses and drafted the paper SB and IS conceived the study, participated in its design and coordination and ... to draft and review the manuscript TF, TC and OKB helped in the data organization and retrieval, English editing and final draft preparation All of the authors have read and approved the final...
... definitions from themetabolicsyndromeThe previous work evaluated this difference and did not analyze the relative weight of each component of themetabolicsyndromeThe importance of the current ... OR and AS have participated in the design of the study, performed the statistical analyses and drafted the paper SB and IS conceived the study, participated in its design and coordination and ... to draft and review the manuscript TF, TC and OKB helped in the data organization and retrieval, English editing and final draft preparation All of the authors have read and approved the final...
... Antiretroviral therapy for HIV may increase the risk of metabolicsyndrome (the clustering of abdominal obesity, hyperglycaemia, dyslipidaemia and hypertension) and thus predispose to type diabetes and ... discuss the evidence on the relationships between TB and DM, andthe possible mechanisms through which this link may be caused, we then discuss the link between antiretroviral therapy (ART), metabolic ... and precursor to DM), increased levels of cholesterol and triglycerides, lipodystrophy, andthe onset or complication of diabetes[18,60] HIV, Metabolic Syndrome, and Heart Disease Metabolic Syndrome...
... resources and needs as a component of thesyndromeThe arrival of the MET brings a critical care environment to the bedside In a sense, when an MET syndrome develops, it could be argued that both the ... power due to the large variance in outcome incidence and wide standard deviation andthe lower-than-expected incidence of the outcome measures under investigation Given the incidence and variance ... of control andthe fact that nurses can activate the MET without requiring permission from them Ignoring these problems and not seeking to reassure medical staff is likely to increase the chance...
... through the lung capillary beds and into the systemic circulation An obvious mechanism is movement of the material through the lungs in the same way they enter into and move through the intestine ... due to the ease of observing events occurring in the eye andthe highly significant consequences of eye damage compared with limited local damage in other areas of the body andthe possible therapeutic ... intestine They can penetrate anywhere, including into the brain through the foramen magnum Once lodged, these structures migrate, andthe rate of migration depends only on the rate of movement of the...
... overweight andobesity vary, with England and Poland showing the steepest increases49 12 EN As relatively few risk factors cause the majority of the chronic disease burden, the related morbidity and ... additional 3.7% and 1.4% due to obesityand physical inactivity – a total of 9.6%, compared with 9% due to smoking16 II.3 A recent report by the Netherlands Institute for Public Health andthe Environment, ... that they not object to having their responses, or parts thereof, published on the Commission’s website and/ or quoted in reports analysing the outcome of the consultation process19 III.4 Given the...
... between obesity, endothelial dysfunction and reduced plasma androgen levels (hypogonadism), and link these pathological states to ED Obesity is a major risk factor for themetabolicsyndrome ... including obesity- related androgen deficiency and obesity- induced endothelial dysfunction Obesity promotes inflammatory responses and contributes to endothelial dysfunction The role of endothelial ... penis; (b) the endothelium lining the cavernosal arteries andthe helicine arterioles, as well as the endothelium lining the lacunar spaces of the corpus cavernsoum; and (c) the endocrine milieu...
... increase the positive control of the ATPin ⁄ ADPin ratio by ATP synthesis andthe negative control by the proton leak The negative control of the ATPin ⁄ ADPin ratio by the ANT increased by 100% and ... substrates, andthe control by the QH2-oxidizing module and hexokinase with succinate The control of the ATPout ⁄ ADPout ratio by the ANT increased by 56% and 113% with succinate and glutamate ... substrate: the response through the ANT contributed 75% of the reduction in Jo, 76% of the reduction in Jp, 68% of the increase in Dw, 88% of the increase in the ATPin ⁄ ADPin ratio, and 69% of the...
... ‘below’ the Q119 guanidiniums of the four domains, holding the domains together and blocking the channel Adding charges (one proton per domain) breaks the plug, the side chains separate, andthe ... was higher in the N–C+ group than in the N+C– group, andthe frequency of metastasis and number of cases with stage D were lower in the N+ group than in the N- group Furthermore, the number of ... of the aromatic ring of the position and amino acid residues seem to be critical for the stimulation of the [35S] GTPcS binding andthe activation of the downstream effector systems PP-76 The...
... involvement for the enzymatic reaction of Lad1 and could also be due to an indirect effect of lad1 knockout on the regulation of other genes On the other hand, the lack of growth of the wildtype ... pentitols and hexitols, most of the substrate-product pairs of Lad1 and SDH are the same, i.e they use the same catalytic mechanism A major difference in the substrate specificity between the two, ... all the amino acids which are involved in polyol binding in the SDH [25] are also absolutely conserved in Lad1, and thus cannot determine the binding efficacy of hexitols and pentitols On the other...
... the web, the resulting vibrations are transmitted and amplified throughout the web These vibrations alert the spider, which moves in for the kill 33 34 the inflammation syndromeThe cells of the ... for the first time in their lives, they’ve been able to “connect the dots” in their inflammatory disorders and then take small and big steps toward regaining their health You can, too! PART I The ... understanding of the science behind the health benefits of nutrition and supplements In many ways, The Inflammation Syndrome expands on the concepts described in my previous book Syndrome X: The Complete...
... WHA55.25) The Regional Office will publish the research papers later this year This publication outlines the extent of the problem, the implications for the health sector and other sectors, andthe ... Regional Office Both the summary andthe larger book illustrate the dynamics of the epidemic and its impact on public health throughout the WHO European Region In particular, theobesity epidemic’s ... exposure to themetabolicsyndromeand show health effects such as diabetes earlier in life Children’s obesity is the clearest demonstration of the strength of environmental influences andthe failure...
... structure [5] These findings raise the interesting question of whether the balance between acharan sulfate and this other GAG species remains unchanged from birth to the adult life of the snail The presence ... from the nacreous layer of the shell from the pearl oyster, Pinctada maxima Although these and other reports suggest the presence of GAGs or proteoglycans in the mollusk shell organic matrix, the ... mucus andthe organic shell matrix Fractionated GAGs from both mucus andthe whole snail body (see above for methodology) were applied to a mm The GAG component of the soft body, mucus and the...