... 3-nitro-L-tyrosine asan internal standard. The coefficient of variation ofintra- and interassay determinations for trp and kyn wasbelow 5%. Recovery of trp and kyn was determined bymeasuring trp and ... biologic response markers,including matrix metalloproteinases (MMPs), beta2microglobulin, MxA, viperin, TNF-related apoptosis-inducing ligand (TRAIL) and X-linked inhibitor apopto-sis factor-1 ... W,Coats ME, Goodkin DE, Weinstock-Guttman B, Herndon RM, et al: Incidence and significance of neutralizing antibodies to interferon beta-1a in multiple sclerosis. MultipleSclerosis Collaborative...
... motor fatigue in multiplesclerosis using kinematic gait analysis: a pilot study. Journalof NeuroEngineering and Rehabilitation 2011 8:59.Sehle et al. Journal of NeuroEngineering and Rehabilitation ... assess multiple sclerosis- related fatigue. Multiple Sclerosis 2009, 15(12):1509-1517.34. Guidelines MSCfCP: Fatigue andMultiple Sclerosis: evidence basedmanagement strategies for fatigue inmultiple ... inmultiple sclerosis. Multiple Sclerosis Council for Clinical Practice Guidelines; 1998.35. Iyengar V, Santos MJ, Ko M, Aruin AS: Grip force control in individualswith multiple sclerosis. Neurorehabilitation...
... acute and chronic MS lesions in brain, (Fig. 3A) andin acute spinalcord lesions (Fig. 3B), corresponding to increases in IL-16.Levels of T-bet in spinal cord were greatest in acutelesions, and ... present our findings on the expression and dis-tinct regulation of pro- and secreted IL-16 in acute, suba-cute and chronic MS lesions, andin normal-appearingwhite matter, from brain and spinal cord ... detected in control brain (A) or spinal cord (B). In MS lesions, relatively high levels T-bet were measured in acute lesions (AL) and chronic lesions (CL) in brain, andin AL in spinal cord....
... Practice in Multiple Sclerosis 1. The History of MultipleSclerosis Care 12. Domains of MultipleSclerosis Nursing Practice 73. Change Theory and Its Application in Multiple Sclerosis Nursing 114. ... domains of MS nursing and define basicroles and responsibilities in each domain4 NURSING PRACTICE INMULTIPLE SCLEROSIS: A CORE CURRICULUMCore Curriculum 01 10/23/02 12:19 PM Page 4B. Definition, ... Domains11. The Symptom Chain inMultipleSclerosis 51ContentsNursing Practice in Multiple Sclerosis: A Core CurriculumKathleen Costello, RN, MS, CRNP, MSCNMaryland Center for Multiple Sclerosis University...
... closely linked with recurrent falls and fractures, lost independence requiring support and care, poor wound healing, and an increase in complications including infections, pressure sores and skin ... and medical factors that can indicate compromised nutritional status in the elderly, the screening tools available to detect malnutrition, and when to involve a dietician.Weight loss andmalnutrition ... to malnutritionand deficiencies in folate, antioxidants and vitamin D.16 The relationship between malnutrition and cognitive function is complex, with malnutrition likely to be a cause and...
... ◾excellenceTeam building ◾Increasing and enhancing communication ◾Professional and leadership development ◾Promoting comparisons and benchmarking ◾Identifying and creating a shared sense of ... is becoming increasingly more sophisticated in iden-tifying constituents and beneficiaries and figuring out how to incorporate them into the process.Considering these opportunities and challenges ... levels are increasingly making better use of the information available to them, which results in more mature approaches to assessment. Collecting InformationComparing InformationAnalyzing InformationFigure...
... design, data collection and analysis, manuscript planning and editing. TV and MOBwere involved in study design, manuscript planning and editing. All authors read and approved the final manu-script.AcknowledgementsWe ... corre-lates of fatigue inmultiple sclerosis. Arch Phys Med Rehabil 1996,77:165-170.17. Krupp LB, Elkins LE: Fatigue and declines in cognitive function-ing inmultiple sclerosis. Neurology 2000, ... multiple sclerosis. InMultiplesclerosis clinical practiceguideline Washington, DC: Paralyzed Veterans Association; 1998. 3. Freal JE, Kraft GH, Coryell JK: Symptomatic fatigue in multiple sclerosis. ...
... compared (planned comparisons) Baseline 1 and Baseline 2 (effect of Robot Training), Baseline 2 and Wash-out (effect of Subject Training) and finally Base-line 1 and wash-out (overall phase effect).ResultsSeven ... regards changes within onesession, to distinguish between the changes in perfor-mance occurring during the Robot Training phase f romthose occurring during the Subject Training phase, wedirectly ... Adaptive robot training for thetreatment of incoordination inMultiple Sclerosis. Journal ofNeuroEngineering and Rehabilitation 2010 7:37.Submit your next manuscript to BioMed Central and take full...
... and the9HPT [29]. For the TEMPA, the median execution timeof the 4 unilateral activities (i.e. grasping and moving ajar, pouring water from a ju g into a cup, inserting coins in a slot, pinching ... technologyenables independent an d repetitive movement practice, and this in a motivating, enriched and interactive virtuallearning environment in which complex motor tasks,involving central neural ... application of resistance-, endurance- and combined training. Mult Scler 2008, 14:35-53.3. Snook EM, Motl R W: Effect of exercise training on walking mobility in multiple sclerosis: a meta-analysis. Neurorehabil...
... role in celladhesion, i.e. slowing and initiating cell rolling, they havebeen shown to have a dominant role in allowing non-spe-cifically activated cells to gain access to the CNS [5], inde-pendent ... ofvarious molecules and cells in the intravascular compart-ment.2 Inflammatory cytokines such as tumor necrosisfactor-α (TNF-α) and interferon-γ (IFN-γ) induce opening and redistribution of ... MK, Raine CS: Medical progress: multiple sclerosis – the plaque and its pathogenesis. N Engl J Med 2006,354:942-985.2. Minagar A, Alexander JS: Blood-brain barrier disruption in mul-tiple sclerosis. ...
... restructuring on daily pain intensity and catastrophizing in individ-uals with multiplesclerosisand chronic pain. Int J Clin Exp Hypn. Jan 2011; 59(1):45–63. 26. Krupp LB. Fatigue inmultiple sclerosis: ... Cause of death in patients attending multiplesclerosis clinics. Neurology. Aug 1991;41(8):1193–6. 32. Feinstein A. An examination of suicidal intent in patients with multiple sclerosis. Neurology. ... disease. Joints including the knees, hips, spine, and hands are subject to degenera-tive changes secondary to overuse and added stress. Symptoms include pain, joint stiffness, and limited...
... training in people with multiple sclerosis. J Sports Sci2006, 24(8):911-914.41. Hassmen P, Koivula N, Uutela A: Physical exercise and psycho-logical well-being: a population study in Finland. ... this study. She wasinvolved in the concept and design, data collection and collation, data analysis, writing and editing of the manu-script. CM was involved in the conception and design ofthe ... fatigue inmultiple sclerosis. Paralyzed Veterans of Amer-ica 1998.11. Petajan JH, White AT: Motor-evoked potentials in response tofatiguing grip exercise inmultiplesclerosis patients. Clin Neu-rophysiol...
... soluble HAL-II.Drs. Minagar and Kelley have contributed to this manu-script by recruiting and examining multiple sclerosis patients, interpretation of data and preparing themanuscript.Dr. Gonzalez-Toledo ... alteration ofsHLA-I and/ or sHLA-II levels as a reflection of diseaseactivity inmultiplesclerosis (MS). Clinical and brainmagnetic resonance imaging (MRI) disease activity in MSis associated ... L,Paolino E, Tola MR, Granieri E, Baricordi OR: Beneficial effect ofinterferon-beta 1b treatment in patients with relapsing-remitting multiplesclerosis is associated with an increase in serum...