... days of stress (data not shown) Initial analysis of the expression of selected genes that are known to be altered by the respective nutrientstress clearly confirmed that the plants were nutrient ... family are depicted Additional file Transcript analysis of known nutrient stress- specific genes Transcript analysis of known nutrient stress- specific genes in leaf and root tissue of hydroponically ... targets, including a stress- induced miRNA Mol Cell 2004, 14:787-799 Sunkar R, Chinnusamy V, Zhu J, Zhu J: Small RNAs as big players in plant abiotic stress responses and nutrient deprivation...
... in the general stressresponse in bacteria [28] Moreover, it has been already observed that acid adaptations, like those described before, confer resistance to a wide range of stress conditions ... (2010) 1896–1905 ª 2010 The Authors Journal compilation ª 2010 FEBS 1897 Structure of acidic stressresponse factor HP1286 L Sisinni et al ˚ higher resolution, 2.1 A Statistics on structure determination ... 1896–1905 ª 2010 The Authors Journal compilation ª 2010 FEBS L Sisinni et al Structure of acidic stressresponse factor HP1286 Table Intersubunit contacts Residues are considered to be in contact...
... physiological stress responses and acquired thermotolerance J Appl Physiol 92, 2177–2186 Samali A, Holmberg CI, Sistonen L & Orrenius S (1999) Thermotolerance and cell death are distinct cellular responses ... Hsp27 (expressed in a constitutive way as a function of cell differentiation status) [7,8] The stressresponse in skin cells also involves inflammatory processes (cytokine release) [9], irreversible ... used human cutaneous cells and hRE to test the hypothesis that exposure to RFR results in cell stressresponse The modulatory effect of GSM-900 exposure on apoptosis induction, epidermis thickening,...
... trigger a secretion stress response, and that the CssRS-dependent response is a general secretion stressresponse Results Nontranslocated pre-AmyQ does not provoke a secretion stressresponse Previous ... secretion stressresponse in B subtilis H Westers et al proteins in B subtilis 168 provokes a CssRS-dependent secretion stressresponse [3,22] To investigate whether this secretion stressresponse ... pre-AmyQ-Ala does not trigger a secretion stress response, whereas translocated AmyQ does elicit a secretion stressresponse The intensity of the secretion stressresponse provoked by translocated AmyQ...
... the response of cells with dysfunctional mitochondria 810 to oxidative stress, we evaluated H2O2 sensitivity of deletion mutants for the regulators most frequently associated with oxidative stress ... Oxford Finkel T & Holbrook NJ (2000) Oxidants, oxidative stress and the biology of ageing Nature 408, 239–247 Jamieson DJ (1998) Oxidative stress responses of the yeast Saccharomyces cerevisiae Yeast ... oxidative stressresponse of Saccharomyces cerevisiae J Biol Chem 274, 27002–27009 Ross SJ, Findlay VJ, Malakasi P & Morgan BA (2000) Thioredoxin peroxidase is required for the transcriptional response...
... feature forms the molecular basis of oxidative stressresponse by these proteins Similarly, an annexin from M sativa was reported to act as stress- response protein [7] and several mammalian annexins ... in oxidative stress X-ray structure of Anx(Gh1) (Eur J Biochem 270) 2563 response Thus, it is very likely that this redox system forms the basis of annexin response to oxidative stress in that ... annexins in the oxidative stressresponse Oxy5, an annexin-like protein from Arabidopsis, was shown to rescue E coli DoxyR mutants and protect mammalian cells from oxidative stress [8,9] In particular,...
... pGL105/C3H cells seemed to be more useful for screening modulators of stressresponse in mammalian cells Induction of stressresponse by SA Enhancement of heat shock promoter activity by SA SA ... SA on stressresponse in mammalian cells using a simple screening system, and revealed that SA is a potent Hsp inducer in mammalian cells, thereby protecting cells against deleterious stress ... Kumari, L (2001) Induction of stressresponse renders human tumor cell lines resistant to curcumin-mediated apoptosis: role of reactive oxygen intermediates Cell Stress Chaperones 6, 368–376 22...
... Cont Stress B Stress CRF Plasma membrane CRFR1 AC Gs ATP cAMP PKA Nucleus PKA P Transcription factor P Relaxin-3 gene Promoter Fig (A) Relaxin-3 mRNA expression in the NI after h of restrained stress ... expression, relaxin-3 mRNA expression in the NI is enhanced by restraint stress or forced swim stress (Fig 2A) [12,28] This swim stress- induced increase in relaxin-3 transcript levels is blunted by ... in this minireview series [36,37] Stressresponse The NI is a region showing abundant expression of CRFR1, and strong c-Fos induction was observed in the NI in response to an intracerebroventricular...
... our results is that of the sensing mechanism for PHQ stress in yeast Hog1 is activated by osmotic stress [33], heat stress [48], oxidative stress [49], bacterial endotoxins [50] and citric acid ... to environmental stresses such as osmotic stress On the other hand, we demonstrated here that activation of Hog1 is required for the development of aneuploidy, which inicts stress on cells This ... PHQ efciently induced aneuploidy in the chk1D strain (Fig S2) Thus, the DNAdamage response did not occur in response to PHQ treatment In the swe1 strain, we observed that PHQ does not cause cell...
... the yeast response to stress expression programmes common to all environmental stress responses are at play [1] Specific forms of stress such as heat shock and some forms of oxidative stress [2] ... proteins and stress response: an overview FEBS Lett 567, 80–85 Toledano M, Delaunay A, Biteau B, Spector D & Azevedo D (2003) Oxidative stress responses in yeast In Yeast Stress Responses (Hohmann ... the major regulator of the oxidative stress response, comparatively less is known about the remaining family members Oxidative stress The response to oxidative stress can be described as the phenomenon...
... common molecular responses to a given stressor The chapters in this book address stressresponse in yeast, plants and humans The topics discussed include acetic acid-induced stressresponse in yeast, ... Metabolism – Cell Homeostasis and StressResponse Oxidative stress and reactive oxygen species Oxidative stress is defined as the rapid production of O2•- and / or H2O2 in response to various external ... environmental stress, plant cells show an increase in ROS levels leading to oxidative stress Indeed, oxidative stress is a major cause of cell damage in plants exposed to environmental stress Plants...
... generate further oxidative stress Multiple biochemical responses are clearly generated by the use of oligoglucans as elicitors of defense responses against oxidative stress The recognition of ... pattern, whatever the nature of the stressor 14 Cell Metabolism – Cell Homeostasis and StressResponse Examples of non-specific indications of the state of stress are: increased respiration, ... in response to drought or salinity without a decrease in cell turgor Regulation of Gene Expression in Response to Abiotic Stress in Plants 15 In plants, dehydration activates a protective response...
... Regulation of Gene Expression in Response to Abiotic Stress in Plants 37 salinity stresses using a fulllength cDNA microarray Plant Journal, Vol.31, pp.279292, ... Vol.23, pp.893-902 38 Cell Metabolism – Cell Homeostasis and StressResponse Zhu, J-K (2001a) Cell signaling under salt, water and cold stresses Current Opinion in Plant Biology, Vol.4, pp 401-406, ... peroxide (H2O2), and hydroxyl radical (OH•) ROS also 40 Cell Metabolism – Cell Homeostasis and StressResponse include the singlet oxygen (1O2), which is not generated by O2 reduction but by energy...
... al., 2008) Stressresponse pathways and key components Under unfavourable environmental conditions, the yeast cell induces a common set of functional changes as a broad response to stress These ... incorporates approximately 50 genes previously described as part of general stressresponse and which bear the stressresponse element (STRE) promoter sequence recognized by Msn2p and Msn4p The ... to different stress conditions, such as those imposed by low water activity and by the presence of cytotoxic compounds Yeast cells react to adverse conditions by triggering a stress response, enabling...
... accumulation of compatible solutes observed during the stressresponse Compatible solutes protect membranes and proteins against stress However, when stress is over, compatible solutes inhibit growth, ... Kuchler, K (2004) Global phenotypic analysis and transcriptional profiling defines the weak acid stressresponse regulon in Saccharomyces cerevisiae Mol Biol Cell, Vol 15, pp 706720 Scorrano, L (2005) ... apoptosis-inducing factor Nature, Vol 397, pp 441446 100 Cell Metabolism Cell Homeostasis and StressResponse Tal, R., Winter, G., Ecker, N., Klionsky, D.J & Abeliovich, H (2007) Aup1p, a yeast...
... 112 Cell Metabolism – Cell Homeostasis and StressResponse Kühlbrandt W Biology, structure and mechanism of p-type ATPases Nature 2004; 5:282295 ... equisimilis Biochemistry 2004; 43(28):9234-9242 114 Cell Metabolism – Cell Homeostasis and StressResponse Tochio T, Tanaka H, Nakata S & Hosoya H Fructose 1,6-bisphosphate aldolase A is involved ... substances with the ability to restrain uranium toxicity 116 Cell Metabolism – Cell Homeostasis and StressResponse Uranium in the environment, routes of entrance to the body and impact on health Uranium...
... neoplasms It was observed an overall response rate of 90.7% with a complete response rate of 70.8% (Karakullukcu et al., 2011) This study also revealed the difference in response rates between different ... formation J Environ Radioact., Vol 64, pp (247 259) 144 Cell Metabolism Cell Homeostasis and StressResponse Miller, A., Stewart, M., & Rivas, R (2010) Preconceptional paternal exposure to depleted ... lead toxicity Neurotoxicology, Vol 14, pp (77-85) 146 Cell Metabolism Cell Homeostasis and StressResponse Smith, D., & Black, S.(1975) Actinide concentrations in tissues from cattle grazing...
... 172 Cell Metabolism – Cell Homeostasis and StressResponse 1.1.1 Protein 1.1.2 Disease 1.1.3 References β-catenin Carcinogenesis, hepatocellular ... topological properties of the hubs are listed in Table 174 Cell Metabolism – Cell Homeostasis and StressResponse breast cancer (Kadota et al., 2009) YWHAZ (14-3-3 protein zeta/delta /Protein kinase ... of 12 steps that has 815627 linear paths, in which 176 Cell Metabolism – Cell Homeostasis and StressResponse only 33 of 68 core proteins (42%) and 1115 of 3251 proteins (32%) are participated,...
... Therapeutic Implication”, Neoplasma, Vol 55, pp 165-176 188 Cell Metabolism – Cell Homeostasis and StressResponse Peifer,M and Polakis ,P., 2000,” Wnt signaling in oncogenesis and embryogenesis-a look ... database”, FEBS Lett., Vol 513, No 1, pp 135-40 190 Cell Metabolism – Cell Homeostasis and StressResponse Zhang, Y et al., 2001, “Differential Molecular Assemblies Underlie the Dual Function ... cellular signaling pathways, but also in areas of renewed interest, such as unique regulation of stressresponse pathways by cancer cells (reviewed in Luo et al., 2009) Regardless of the pathway targeted,...