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neurological control of sexual function in health and disease

gut bacterial activity in a cohort of preterm infants in health and disease

gut bacterial activity in a cohort of preterm infants in health and disease

Tổng hợp

... material daily in a healthy adult Adults also both ferment and recycle the products of protein metabolism, including hydrolysis of urea, deamination of amino acids, and recycling of ammonia Nitrosation ... Species turnover Figure 93: Interindividual similarity indices of EEBM and MF fed infants Figure 94: Percentage of interindividual similarities of EBM and MF infants Figure 95: Individual value plot ... activity in a cohort of preterm infants in health and disease Dr Lynne Mary Beattie, MRCPCH MBChB PGCertMedEd Submitted in fulfilment of the requirements for the degree of Doctorate of Medicine School...
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Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

Báo cáo khoa học

... involved in ligand binding, presumably abolishing the interaction with signaling partners The remaining mutations alter amino acids located outside the ligand-binding pocket and reduce protein ... lymphoproliferative disease Arginine 335 is found in the ‘BG loop’ not involved in phosphotyrosine binding and mutation to tryptophan most probably causes instability of the SH2 domain Thus, these ... protein kinase B (PKB)] In AKT, a cysteine substitution of the corresponding R25 in the pleckstrin homology (PH) domain also results in loss of function [16,17], thereby demonstrating related functions...
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Báo cáo y học:

Báo cáo y học: "Tibialis posterior in health and disease: a review of structure and function with specific reference to electromyographic studies" pot

Báo cáo khoa học

... walking in health and disease Tibialis Tibialis posterior EMG activity during walking in health and disease Tibialis posterior EMG activity during walking in health and disease – schematic estimates ... and effective method of investigating tibialis posterior EMG during walking Tibialis posterior EMG in health and disease Current literature has characterised TP EMG during gait among normal and ... during gait, further work is required to more fully understand the role of TP in the development of pathology and in disease- specific populations including RA, cerebral palsy and TPTD Page of...
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The Potential of Biofumigants as Alternatives to Methyl Bromide for the Control of Pest Infestation in Grain and Dry Food Products

The Potential of Biofumigants as Alternatives to Methyl Bromide for the Control of Pest Infestation in Grain and Dry Food Products

Sinh học

... phosphine is a quick and effective tool for the control of stored-product insect pests In view of the scheduled phaseout of methyl bromide under the Montreal protocol, the role of phosphine in grain ... availability of plant essential oils and their terpenoids, and their use in cosmetics and as flavoring agents in food and beverages, is a good indication of their relative safety to warm-blooded animals and ... followed by CS2 and C7 H6 O CS2 , according to Winburn (1952), was one of the most effective grain fumigants as viewed from efficiency and low cost points of view C7 H6 O occurs in kernels of bitter...
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Diffusion and Use of Genomic Innovations in Health and Medicine: Workshop Summary pot

Diffusion and Use of Genomic Innovations in Health and Medicine: Workshop Summary pot

Sức khỏe giới tính

... the field of ­genomics and improve the translation of research findings to health care, public health, and health policy As a first step in examining issues of translation of genomic innovations, ... understanding of the role of technology and of organizational innovation in the broader economy and especially in health care If certain types of innovation can provide a solution to problems of ... Diffusion and Use of Genomic Innovations in Health and Medicine: Workshop Summary http://www.nap.edu/catalog/12148.html Diffusion and Use of Genomic Innovations in Health and Medicine workshop...
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Báo cáo khoa học: Regulation of matrix metalloproteinase activity in health and disease pdf

Báo cáo khoa học: Regulation of matrix metalloproteinase activity in health and disease pdf

Báo cáo khoa học

... illustrated in Fig 2B (step 1) Interactions with small integrin-binding ligand N-linked glycoprotein (SIBLING) Individual members of the SIBLING family are known to bind strongly to both pro- and active ... autocatalytic step of the activation by binding to the 64 kDa intermediate form of MMP-2 [52] Binding and activation of MMP-2 was abrogated in the presence of avb3 integrin-binding macromolecules ... proMMP-binding partners involved in activation Allosteric activation Gelatinase interactions with collagen and gelatin Binding of macromolecules or specific thiol-binding reagents to an MMP with an intact...
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Báo cáo khoa học: Proteoglycans in health and disease: the multiple roles of syndecan shedding ppt

Báo cáo khoa học: Proteoglycans in health and disease: the multiple roles of syndecan shedding ppt

Báo cáo khoa học

... occludens-domain-containing proteins such as syntenin, Ga-interacting protein (GAIP)-interacting C-terminus ⁄ synectin and calcium ⁄ calmodulin-associated serine kinase, since the C2 region contains a ... syndecans, and are endopeptidases belonging to the family of metzincins (zinc endopeptidases) which contain three major multigene families: seralysins, astacins and a disintegrin and metalloproteinase ... HEXXHXXGXXH) and a conserved methionine (Met-turn) supporting the catalytic zinc Interaction between cysteine–zinc maintains proMMPs in an inactive state by preventing a water molecule from binding to...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx

Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx

Báo cáo khoa học

... results in increased sulfation of HSPGs, sustained association of heparin-binding growth factors with their cognate receptors and augmented downstream signaling Expression of HSulf-1 in cell lines ... enriched in lung carcinoma and chronic myeloid leukemia compared with control tissue and cells In this splice variant, 144 bp of intron are joined with exon 4, resulting in a 169-amino-acids protein ... role of heparanase in human cancer by focusing on head and neck carcinoma and multiple myeloma as examples of solid and hematological malignancies Heparanase in head and neck carcinoma: signaling...
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The Maternal Management of Children, in Health and Disease ppt

The Maternal Management of Children, in Health and Disease ppt

Sức khỏe giới tính

... 66 During Infancy - 66 During Childhood - 69 V Bathing and Cleanliness - 72 During Infancy - 72 During Childhood - 75 VI Clothing - 78 During Infancy - 78 During Childhood - 81 VII Air and Exercise ... child is in the act of sucking, and an exhausted feeling of sinking and emptiness at the pit of the stomach afterwards This is soon followed by loss of appetite, costive bowels, and pain on the ... in age, animal food may be taken daily Too low a diet would stint the growth of such a child, and induce a state of body deficient in vigour, and unfit for maintaining full health: scrofula and...
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Báo cáo y học:

Báo cáo y học: " Interrelated modulation of endothelial function in Behcet''''s disease by clinical activity and corticosteroid treatmen" ppt

Báo cáo khoa học

... effects of corticosteroid treatment on endothelial function in patients with chronic inflammatory diseases Interestingly, administration of corticosteroids improves endothelial function in patients ... risk factors in control individuals and in patients with Behçet's disease (BD) divided according to the receipt (+) or nonreceipt (-) of corticosteroid treatment and the clinical disease status ... main finding of the cross-sectional observational study was that endothelial function in patients with BD is modulated by both clinical disease activity and use of corticosteroids, albeit in...
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báo cáo khoa học:

báo cáo khoa học: "Systematic evaluation of implementation fidelity of complex interventions in health and social care Henna Hasson1,2,3" pdf

Báo cáo khoa học

... implementation of complex interventions The aim of this project is to evaluate systematically implementation fidelity and possible factors influencing fidelity of complex interventions in health and social ... discovery of problems, earlier care and rehabilitation efforts and changes in care and rehabilitation plans, better uptake of older people’s viewpoints Maintained functional ability, increased ... used to investigate the implementation processes of three intervention studies Thus, a case is defined as an intervention study Each case will be investigated in depth and longitudinally, using both...
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Báo cáo y học:

Báo cáo y học: "Enigma variations: control of sexual fate in nematode germ cells" docx

Báo cáo khoa học

... elegans, including spermatogenesis It binds the transmembrane receptor TRA-2 and inhibits its activity in XO animals, causing male development The inactivation of TRA-2 permits three interacting cytoplasmic ... later in life, suggesting that in hermaphrodites too the FEM proteins are required to maintain the ability to produce sperm The FEM proteins are therefore active in the germlines of both sexes in ... Spence AM, Coulson A, Hodgkin J: The product of fem-1, a nematode sex-determining gene, contains a motif found in cell cycle control proteins and receptors for cell-cell interactions Cell 1990,...
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Tài liệu Aneuploidy in Health and Disease Edited by Zuzana Storchova doc

Tài liệu Aneuploidy in Health and Disease Edited by Zuzana Storchova doc

Sức khỏe giới tính

... suggesting other factors influencing the DNA strand breaks The increasingly detailed map of human DNA will certainly bring new insight into the possible links between DNA secondary structure and ... Defects in SAC lead inevitably to high chromosome missegregation levels both in vitro and in vivo and thus to aneuploidy Besides mutations in spindle assembly checkpoint and in mitotic spindle ... spindle assembly checkpoint and often remain uncorrected, resulting in lagging chromosomes and aneuploidy, F syntelic attachments lead to incorrect chromosome segregation, G defects in SAC interfere...
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Modern Nutrition in Health and Disease pot

Modern Nutrition in Health and Disease pot

Sức khỏe giới tính

... cones of the eye and decline in weight gain of infant monkeys fed a taurine-free diet were prevented by supplements of taurine In premature infants maintained on TPN without taurine, plasma taurine ... before urinary creatinine excretion returns to baseline, indicating that creatine in the diet per se affects creatinine production ( 38) Therefore, consumption of creatine and creatinine in meat-containing ... terminus, and aminopeptidases secreted in intestinal juice at the amino terminus Figure 2.17 Digestion and absorption of dietary protein in the intestine The secretion and feedback system of the...
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The Neuronal Environment: Brain Homeostasis in Health and Disease pot

The Neuronal Environment: Brain Homeostasis in Health and Disease pot

Điện - Điện tử

... sustain the required level of metabolites and to remove waste products The Neuronal Environment: Brain Homeostasis in Health and Disease examines the function of all the components involved, including ... subpopulation of glial cells Astrocytes are involved in a number of different processes, including the control of ionic homeostasis, control of neuronal metabolism, as well as maintenance of blood–brain ... involved in the control of brain homeostasis, since their powerful effect on the control of cerebral perfusion will be the final determinant of the amount of oxygen and glucose delivered to the brain,...
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Báo cáo khoa học: Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans ppt

Báo cáo khoa học: Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans ppt

Báo cáo khoa học

... commonality of signaling between lumican and decorin is also supported by recent studies showing the involvement of decorin in modulating various integrins in controlling proliferation, adhesion and ... overlapping with the EGF-binding domain [32] The structural constraints of the EGFR binding region support a stochiometry of : for the decorin protein core and EGFR, suggesting that decorin is ... lumican in the regulation of cell signaling has not been studied in great detail In analogy to decorin, lumican inhibits tumor cell growth in soft agar by increasing the expression of the cyclin-dependent...
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Lipoproteins – Role in Health and Diseases by Saša Frank and Gerhard Kostner doc

Lipoproteins – Role in Health and Diseases by Saša Frank and Gerhard Kostner doc

Sức khỏe giới tính

... Insights into the Assembly and Metabolism of ApoB-Containing Lipoproteins from in vivo Kinetic Studies: Results on Healthy Subjects and Patients with Chronic Kidney Disease 21 Benjamin Dieplinger and ... though, one has to keep in mind that these domains are not static or confined in size and number and co-determine the intrinsic dynamics of LDL Based on these types of findings, it seems reasonable ... from the blood of human probands and the New Insights into the Assembly and Metabolism of ApoB-Containing Lipoproteins from in vivo Kinetic Studies: Results on Healthy Subjects and Patients with...
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BIOACTIVE FOOD PEPTIDES IN HEALTH AND DISEASE pot

BIOACTIVE FOOD PEPTIDES IN HEALTH AND DISEASE pot

Sức khỏe giới tính

... Peptides in Health and Disease Type of sample Soft Tofu Soft Tofu Silken Tofu Kinugoshi Silken Tofu Silken Tofu Medium firm Tofu Organic Medium firm Tofu Firm Tofu Extra firm tofu Chinese style ... antiinflammatory drugs, and the risk of upper gastrointestinal bleeding New England Journal of Medicine 2000;343:834-9 [53] Laine L Review article: Gastrointestinal bleeding with low-dose aspirin: ... active site of the enzyme and the formation of tight inhibitory complexes An understanding of the role played by serine proteases and their specific inhibitors in human diseases offers novel and challenging...
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Immunosuppression – Role in Health and Diseases Edited by Suman Kapur and Maristela Barbosa Portela ppt

Immunosuppression – Role in Health and Diseases Edited by Suman Kapur and Maristela Barbosa Portela ppt

Sức khỏe giới tính

... cellular and molecular understanding of ET will serve as a key step towards understanding of immunosuppression and its targeting in many diseases 12 Acknowledgment SKB and INS are supported by funding ... chemokines and chemokine receptors, in leukocytes Chemokines induce cellular migration and are crucial players in initiating both innate and adaptive immune response (Figure 7) A series of very ... of very early inflammatory events induce activation of tissue and endothelial cells and culminates in production of chemokines such as interleukin-8 (IL-8) that induce migration of neutrophils...
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