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neuroendocrine modulation of cell mediated immunity and cancer development in the perioperative period

Is there information in financial analysts forecasts about firms that subsequently restate their earnings

Is there information in financial analysts forecasts about firms that subsequently restate their earnings

Tổng hợp

... on the firms, including the decrease in expected future earnings and the increase in cost of capital (Hribar and Jenkins, 2004) We are interested to examine the role of financial analysts in ... suppliers, and its industry warrants them the service fee However, the growing number of earnings restatements and the accompanying problems in financial reporting bring about many criticisms on the financial ... perception of the management’s credibility and the financial reporting quality, and thereby increases the firms’ cost of capital (Hribar and Jenkins 2004) We are interested to investigate whether the...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "The Structure of User-Adviser Dialogues: Is there Method in their Madness?" pdf

Báo cáo khoa học

... Thus, the node N-1 immediately dominates N, the node N-2 dominates N-I, and so on The nodes subordinate to each of the nodes dominating N are indexed beginning with the left-most node and proceeding ... about the nature of dialogue structures, about the validity and usefulness of the concept of a dialogue structure, about the role of the task structure in determining dialogue structure, and in the ... attempt to find evidence linking the dialogue structure to the task structure The main point is that the structure of the intentions conveyed in the discourse should mirror to some extent the task...
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báo cáo hóa học:

báo cáo hóa học:" CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?" pdf

Hóa học - Dầu khí

... actively exploring some of these exciting avenues of investigation Chemotherapy We have investigated this hypothesis further by examining the timing of chemotherapy doses with respect to the LCRP immune ... of colorectal cancer and independently associated with the increased risk of colorectal cancer in men [14], and overall cancer risk [15] Interleukin-6 (IL-6) has been used for the diagnosis of ... substantiate the current observations Examining the Hypothesis Vaccinations We have examined this hypothesis by taking L-CRP measurements over the weeks surrounding the vaccination times of patients...
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báo cáo hóa học:

báo cáo hóa học: " Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008" pot

Hóa học - Dầu khí

... that pain and appetite loss are independent determinants of overall survival One found that a 40-point increase in the pain subscale of the EORTC QLQ-C30 was associated with a 27% increase in the ... each other, in many instances when one includes both physical functioning and performance status in the regression models, the likelihood of finding inconsistent results can be expected In other ... study sample, type of cancer (where relevant data were available), instrument used to measure quality of life, and the main findings or conclusions The findings were then sorted and presented chronologically...
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báo cáo hóa học:

báo cáo hóa học:" Pain in cancer. An outcome research project to evaluate the epidemiology, the quality and the effects of pain treatment in cancer patients" pptx

Hóa học - Dầu khí

... pattern of care and main outcomes, and a discussion of the feasibility of this kind of approaches in the specific setting, the second about the effects (effectiveness) of treatments on patients (and ... expected: the first reporting on the results of the "epidemiological" part of the study, including a description of patients' characteristics in terms of baseline socio-demographic and clinical ... to conduct and monitor the progress of the trial for the patients' safety and according to the World Medical Association Declaration of Helsinki and the European and Italian Good Clinical Practice...
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Báo cáo khoa học:

Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps

Báo cáo khoa học

... needle is introduced into the last portion of internal jugular vein This vein was reached through the transducer placed at the point of insertion of the sternocleidomastoid muscle into the clavicular; ... removal of the CVC The follow-up consisted of: patient’s clinical examination, catheters flushed with heparinized solution and catheter exit side dressing Assesment of endpoints The primary endpoints ... allowed the completion of the therapeutic program for 1,930/ 1,978 (97.6%) of the catheters inserted The absence of pneumotorax and other major complications indicates that US guidance should be mandatory...
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Báo cáo khoa học:

Báo cáo khoa học: "Perioperative immune responses in cancer patients undergoing digestive surgeries" pptx

Báo cáo khoa học

... in the design of the study and writing of the manuscript MN and NH assembled the data TM and YK performed the statistical analysis HI and HK performed the study of flowcytometry YN designed the ... Distribution in Th1 and Th2 subsets of CD4+T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression Cancer Immunol Immunother 1996, 42:1-8 ... IFN-γ+T cells were not seen other than the reduction on POD in the hepatic resection group found On the other hand, there were also no significant differences in the percentage of CD4+IL-6+ T cells...
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Báo cáo khoa học:

Báo cáo khoa học: " Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence" doc

Báo cáo khoa học

... both in monomeric (active) and dimeric (inactive) state [16] The protein contains several important domains such as 1) the C-terminal protein kinase domain (PI3K-domain), 2) the substrate binding ... assess the possible functional effect of a sequence variation in the coding regions of the ATM gene resulting in an amino-acid substitution in the protein sequence The online tool scores the effect ... substrate binding domains and ATPbinding domains, is illustrated in Figure Single marker associations Risk for developing breast cancer The association between any variant in the ATM gene and risk of...
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báo cáo khoa học:

báo cáo khoa học: "The potential benefits of low-molecular-weight heparins in cancer patients" ppsx

Báo cáo khoa học

... anticoagulation over the course of the increased risk of VTE (during and postsurgery) with the minimum of adverse events such as post-operative bleeding For cancer patients, there is also increasing evidence ... variety of patient-, cancer- and treatment-related factors including age, race and immobility status, together with site or stage of the cancer, whether or not the patient is receiving chemotherapy, ... bleeding Given the period of post-operative VTE risk, data increasingly support extended-duration prophylaxis beyond the period of hospitalization The practical and pharmacokinetic advantages of the...
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Báo cáo y học:

Báo cáo y học: "Is Phytalgic® a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and risk-of-bias assessment" pot

Báo cáo khoa học

... a fishy taste in the mouth might certainly cause detection bias Assessment of the trial reporting in terms of risk of bias, the use of random assignment, and subsequent concealment of allocation ... Aalborg, Denmark Competing interests The funding agencies (The Oak Foundation and The Danish Rheumatism Association) had no role in writing the report or in the decision to submit the manuscript for ... the taste of fish oil during a 3-month trial, probably as difficult as it is to hide the taste of ginger [5] Finally, deviations from protocol and loss to follow-up often lead to the exclusion of...
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Báo cáo khoa học:

Báo cáo khoa học: "Performance of six severity-of-illness scores in cancer patients requiring admission to the intensive care unit: a prospective observational study" pot

Báo cáo khoa học

... in oncology and/ or R195 intensive care, and take part in regular training of oncology and intensive care nurses The nurse/patient ratio ranges from 1.2 to 1.7 Routine clinical rounds, including ... the impact of missing data on the performance of models; in the present study prothrombin time, and serum albumin and bilirubin were not obtained in all patients The differences between the predicted ... patients (with a diagnosis of cancer) may be admitted because of life-threatening illness identified during assessment of the extent of their cancer and/ or consideration of the therapeutic options This...
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Báo cáo y học:

Báo cáo y học: "Clinical review: Specific aspects of acute renal failure in cancer patients" pot

Báo cáo khoa học

... cytoreductive therapy and develops in 20% to 40% of BMT recipients [47] Amphotericin during conditioning Acyclovir during conditioning Vancomycin during conditioning The main site of liver damage in this ... with many anti -cancer agents, including gemcitabine, bleomycin, cisplatin, CCNU, cytosine arabinoside, daunorubicin, deoxycoformycin, 5-FU, azathioprine and interferon α [25] Lastly, the association ... chains bind to a specific peptide domain on the Tamm-Horsfall protein [17]; variations in CDR3 in both the κ and λ light chains influence binding [20] Additionally, hypovolaemia, sepsis, urinary...
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Báo cáo khoa học:

Báo cáo khoa học: "N-terminal pro-brain natriuretic peptide as an early prognostic factor in cancer patients developing septic shock" pdf

Báo cáo khoa học

... during the ICU stay: age and gender; chronic health status as evaluated using the Charlson comorbidity index [15]; characteristics of the malignancy, including the number of previous courses of ... that they have no competing interests Authors' contributions DM collected and analyzed the data and reviewed and coordinated the study AS and MF collected and analyzed the data J-PB, J-LB, DB, and ... consent of the patients or next of kin, we performed the study in 51 consecutive adult cancer patients with medical septic shock Septic shock was defined according to the criteria of the American...
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Báo cáo y học:

Báo cáo y học: " C-reactive protein in critically ill cancer patients with sepsis: influence of neutropenia" doc

Báo cáo khoa học

... study, individual organ failures were diagnosed in case of a SOFA score ≥ points in each domain [14] In addition, patients receiving dialysis in the context of acute kidney injury and invasive ... according to the suspected primary focus of infection Demographic, clinical and laboratory data were collected using standardized case report forms during the first day of ICU stay including main ... in patients with febrile neutropenia to assess their performance in the diagnosis of infection [18-24], in the identification of the underlying agents [18-20,22,24], in the characterization of...
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báo cáo khoa học:

báo cáo khoa học: "Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials" ppt

Báo cáo khoa học

... with those obtained in other studies that have investigated the addition of another drug in the taxane-based chemotherapy In the study of Albain et al [28], the addition of gemcitabine to paclitaxel ... following steps: definition of the outcomes (definition of the question the analysis was designed to answer), definition of the trial selection criteria, definition of the search strategy, and ... the combination of clinical and molecular factors will guide the clinician in identifying the most effective therapy for a given patient, leaving more space and giving more importance to the molecular...
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The NR4A orphan nuclear receptors are target genes of the novel drug c1 in cancer cells and potential mediators of drug induced apoptosis

The NR4A orphan nuclear receptors are target genes of the novel drug c1 in cancer cells and potential mediators of drug induced apoptosis

Cao đẳng - Đại học

... separates the aminoterminal DNA-binding domain of the enzyme from the carboxy-terminal catalytic domain resulting in the loss of normal PARP1 function Although the role of PARP in apoptosis remains ... photodynamic therapy for the derivation of molecules of interest in cancer therapy including photofrin, purpurins, xanthenes, phthalocyanines, oxazines, cyanines, chlorines (Pervaiz, 2001; Pervaiz and ... associated proteins, and intermediate filament proteins including vimentin keratin and nuclear lamins (Luthi and Martin, 2007; Taylor et al., 2008) Caspase mediated clevage of the protein kinase ROCK1...
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The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis

The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis

Môi trường

... for binding to proteins containing LXCXE motifs while the pocket-domain and the C-domain are involved in binding E2F proteins Mdm2 (as well as c-Abl) binds to the C-domain All pocket proteins ... made in cells lacking pRb in the retina Somatic inactivation of pRb, even in the absence of p107 and p53, in the outer nuclear layer had no obvious consequences, indicating that in some settings ... elucidated the function of pRb in controlling cell cycle progression, providing a platform to understand the relevance of pRb loss in development of cancer (reviewed in Weinberg 1995; Hanahan and Weinberg...
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báo cáo khoa học:

báo cáo khoa học: "Chemoradiotherapy followed by surgery versus surgery alone in esophageal cancer patients: is it time for additional evidence?" doc

Báo cáo khoa học

... Visbal AL, Horgan AM, Guindi M, Hornby J, Xu W, Ringash J, Keshavjee S, Chen E, Haider M, Darling G: Phase trial of preoperative irinotecan plus cisplatin and conformal radiotherapy, followed by ... Mayer R: Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781 J Clin Oncol 2008, 26(7):1086-92 ... Oncology Group; Australasian Gastro-Intestinal Trials Group: Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial...
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Báo cáo khoa học:

Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx

Báo cáo khoa học

... clavicular fossa and above the seventh rib Any relapse involving the axillary lymph nodes, and/ or other nodes in the infra or supraclavicular fossa or in the internal mammary chain was considered ... supraclavicular and internal mammary lymph nodes alone) Local recurrence was defined as any relapse in the area of surgery between the sternum and the anterior axillary line, and below the inferior ... time, the role of PMRT for women with to positive lymph nodes remains uncertain and is being examined in a randomized clinical trial” Many surgeons and radiation oncologist are not recommending...
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báo cáo hóa học:

báo cáo hóa học:" Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients" pot

Hóa học - Dầu khí

... various cancer cell lines, including gastric cancer cells, colon cancer cells, breast cancer cells, lung cancer cells, bladder cancer cells, renal cancer cells, and melanoma cells [22] In the present ... expression of these splicing variants was shown only in the thymus [22] We then analyzed the survivin expression in the protein level In all the oral cancer cell lines examined in the present ... blotting analysis of survivin protein in oral cancer cell lines Western blotting analysis of survivin protein in oral cancer cell lines Lysates from oral cancer cell lines or normal oral mucosal...
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