network drivers part 1 data structures

progress in botany. 73 [electronic resource]

Ngày tải lên : 29/05/2014, 23:58

... S3 þE1 ! E1 E2 S3 k8f, k8r E1 S1 ! E1 S2 k9f, k9r 10 E2 S2 ! E2 S3 k10f, k10r 11 E1 S1 E2 ! E1 S2 E2 k11f, k11r 12 E1 S2 E2 ! E1 E2 S2 k12f, k12r 13 E1 E2 S2 ! E1 E2 S3 k13f, k13r 14 E1 S1 E2 ... E1 S1 E2 S2 k14f, k14r 15 E1 S2 E2 þ S2 ! E1 S2 E2 S2 k15f, k15r 16 E1 S2 E2 þ S3 ! E1 S2 E2 S3 k16f, k16r 17 E1 E2 S2 þ S1 ! E1 S1 E2 S2 k17f, k17r 18 E1 E2 S2 þ S2 ! E1 S2 E2 S2 k18f, k18r 19 ... 19 E1 S1 E2 þ S3 ! E1 S1 E2 S3 k19f, k19r 20 E1 E2 S3 þ S1 ! E1 S1 E2 S3 k20f, k20r 21 E1 E2 S3 þS2 ! E1 S2 E2 S3 k21f, k21r 22 E1 S1 þ E2 S2 ! E1 S1 E2 S2 k22f, k22r 23 E1 S1 þ E2 S3 ! E1 S1 E2...

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Báo cáo khoa học: Protein–protein interactions and selection: yeast-based approaches that exploit guanine nucleotide-binding protein signaling doc

Ngày tải lên : 06/03/2014, 11:20

... lessons FEBS Journal 277 (2 010 ) 19 82 19 95 ª 2 010 The Authors Journal compilation ª 2 010 FEBS 19 91 Screening systems using yeast G-protein signaling 10 11 12 13 14 15 16 17 18 J Ishii et al learned ... (2005) Towards a 19 92 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 proteome-scale map of the human protein–protein interaction network Nature 437, 11 73 11 78 Paravicini G & Friedli L (19 96) Protein–protein ... Acta 17 83, 13 81 13 95 Fields S & Song O (19 89) A novel genetic system to detect protein–protein interactions Nature 340, 245–246 Gyuris J, Golemis E, Chertkov H & Brent R (19 93) Cdi1, a human G1...

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Báo cáo khoa học: Protein–protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information potx

Ngày tải lên : 06/03/2014, 11:20

... 277, 19 82 19 95 Tomizaki K, Usui K & Mihara H (2 010 ) Protein– protein interactions and selection: array-based techniques for screening disease-associated biomarkers 2 012 15 16 17 18 19 20 21 22 ... both afﬁnity and size 10 11 12 13 14 References Winter G, Grifﬁths AD, Hawkins RE & Hoogenboom HR (19 94) Making antibodies by phage display technology Annu Rev Immunol 12 , 433–455 Watanabe H, ... Proc Natl Acad Sci USA 10 1, 12 467 12 472 39 Fellouse FA, Li B, Compaan DM, Peden AA, Hymowitz SG & Sidhu SS (2005) Molecular recognition by a binary code J Mol Biol 348, 11 53 11 62 40 Koide A, Bailey...

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Báo cáo y học: "Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspect" potx

Ngày tải lên : 14/08/2014, 08:21

... http://genomebiology.com/2008/9/4/R69 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Genome Biology 2008, Sirotkin K: dbSNP: the NCBI database of genetic variation Nucleic Acids Res 20 01, 29:308- 311 Jiang ... 0.2 0 .1 0 .1 0 200 400 600 Buried 800 1, 000 1, 200 1, 400 1, 600 1, 800 2,000 Protein length (c) (e) (d) 0.4 0.4 0.4 0.3 SNP A/S ratio Exposed Solvent accessibility 0.3 0.3 0.2 0.2 0.2 0 .1 0 .1 0 .1 0 ... Natl Acad Sci USA 2005, 10 2 :14 338 -14 343 Plotkin JB, Fraser HB: Assessing the determinants of evolutionary rates in the presence of noise Mol Biol Evol 2007, 24 :11 13 -11 21 Duret L, Mouchiroud D:...

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Development of a novel toll like receptor based two hybrid assay for detecting protein protein interactions and its application in the study of CD14 dimerization and FcyRIIA activation

Ngày tải lên : 12/09/2015, 08:20

... receptor (TLR1) and Toll-like receptor (TLR2) 11 1. 2.2 .1 Genes and structure 11 1. 2.2.2 Gene expression 14 1. 2.2.3 Ligands and functions 14 1. 2.3 17 TLR signaling 1. 2.3 .1 TIR domain 17 1. 2.3.2 MyD88-dependent ... complex 28 1. 3.3 Mechanism of IL-4R activation 29 1. 4 CD14 31 1.4 .1 The CD14 gene and its expression 31 1.4.2 Structure 32 1. 4.3 CD14 functions 35 1. 4.4 LPS binding to CD14 36 1. 4.5 CD14 and its ... 12 / 13 and 13 on its dimerization 12 2 4.3 Effect of CD14 mutation on its response o LPS 12 4 4.4 Cell surface expression of CD14 and CD14 mutants 12 7 4.5 Detection of CD14-CD14 dimers 13 0 5.1...

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Báo cáo khoa học: On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes ppt

Ngày tải lên : 23/03/2014, 17:22

... and azalides Structure 11 , 329–338 11 Lill, R & Wintermeyer, W (19 87) Destabilization of codon– anticodon interaction in the ribosomal exit site J Mol Biol 19 6, 13 7 14 8 12 Rheinberger, H.J., Sternbach, ... ribosome Nature 342, 14 2 14 8 14 Noller, H.F., Yusupov, M.M., Yusupova, G.Z., Baucom, A & Cate, J.H (2002) Translocation of tRNA during protein synthesis FEBS Lett 514 , 11 16 15 Yonath, A (2002) ... Science 256, 14 16 14 19 20 Odom, O.W., Picking, W.D & Hardesty, B (19 90) Movement of tRNA but not the nascent peptide during peptide bond formation on ribosomes Biochemistry 29, 10 734 10 744 21 Porse,...

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Tài liệu Báo cáo khoa học: Cobalamin uptake and reactivation occurs through speciﬁc protein interactions in the methionine synthase–methionine synthase reductase complex docx

Ngày tải lên : 18/02/2014, 08:20

... (nmolÆmin )1) 70 0. 01 ± 0. 01 0.02 ± 0. 01 0.02 ± 0. 01 0 .13 0. 91 0.75 1. 12 0.09 0 .18 ± ± ± ± ± ± 0. 01 0 .14 0.02 0.04 0.02 0.02 0.06 1. 23 1. 20 1. 19 0.20 0 .19 ± ± ± ± ± ± 0. 01 0 .15 0 .10 0.03 0. 01 0.02 ... eluate 19 44 Total activity (nmolÆmin )1) Specific activity (nmolÆmin )1 mg )1) Yield (%) Purification n-fold 8500 18 80 0.3 410 0 210 0 420 0.5 1. 1 15 40 10 0 50 10 2.3 3669 FEBS Journal 276 (2009) 19 42 19 51 ... reveal that CPR has the greatest specificity for AqCbl, with MSR (10 .6 · 10 5 m )1 s )1) (4 .1 · 10 5 m )1 s )1) and nNOSred (1. 5 · 10 5 m )1 s )1) working less effectively with this substrate We demonstrated...

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Tài liệu Báo cáo khoa học: Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1b mRNA doc

Ngày tải lên : 18/02/2014, 14:20

... containing 1% SDS, 10 mm EDTA, 50 mm Tris ⁄ HCl, pH Lysates were centrifuged at 14 000 g for 10 at °C, and the supernatant obtained was diluted 10 -fold using IP buffer [0. 01% SDS, 1. 1% Triton X -10 0, 1. 2 ... (2009) 7386–7399 ª 2009 The Authors Journal compilation ª 2009 FEBS D Mizgalska et al 10 11 12 13 14 15 16 17 18 disorder in proteins from the three kingdoms of life J Mol Biol 337, 635–645 Vullo ... centrifuged (at 14 000 g, 10 min, °C) and washed twice each with four buffers (B-I: 0 .1% SDS, 1% Triton X -10 0, mm EDTA, 15 0 mm NaCl, 20 mm Tris ⁄ HCl, pH 8; B-II: 0 .1% SDS, 1% Triton X -10 0, mm EDTA,...

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Tài liệu Báo cáo khoa học: The conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein Characterization of cold denaturation and urea–protein interactions doc

Ngày tải lên : 19/02/2014, 12:20

... (kcalặmol )1) DHmcÂ (kcalặmol )1) DSmÂ (calặmol -1 K -1) DSmcÂ (calặmol )1 K )1) ThÂ (K) 256 262 266 267 275 282 58 48 43 43 31 24 )58 )45 )40 )40 )29 )23 17 0 14 4 12 9 13 1 96 77 )228 )17 1 )15 3 )15 1 )10 6 ... calặmol )1 K )1 and 10 12 calặmol )1 K )1 M )1, respectively; (C), at 293 K, 3.5 1. 0 kcalặmol )1, and 1. 5 0.8 kcalặmol )1 M )1; and, at 318 K, 2.2 1. 8 kcalặmol )1, and 1. 2 0.9 kcalặmol )1 M )1 The values ... ) 81 285 288 2 91 290 294 296 c 0.3 0 .1 0.3 0.5 2 3 2 2 3 6 10 10 10 9 DCpÂ (kcalặmol )1 K )1) TsÂ (K) 3 3 289 2 91 293 292 296 297 3 1. 05 1. 06 1. 03 1. 16 1. 15 1. 4...

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Tài liệu Báo cáo Y học: Ligand interactions and protein conformational changes of phosphopyridoxyl-labeled Escherichia coli phosphoenol pyruvate carboxykinase determined by ﬂuorescence spectroscopy pdf

Ngày tải lên : 21/02/2014, 01:21

... s1 (ns) f1 s2 (ns) f2 v2 ATP, Mn2+ PEP, Mg2+ PEP, Mn2+ ATP, oxalate, Mg2+ 5 .15 5.27 5.52 6 .10 5.75 0.34 0.37 0.47 0. 51 0.45 1. 21 1 .17 1. 10 1. 14 1. 00 0.66 0.63 0.53 0.49 0.55 1. 1 1. 06 1. 12 1. 06 ... Kd (lM) 17 .4 14 00 18 00 24 33.8 24.8 12 8 508 0.24 53.8 10 300 13 700 15 6 26 13 6 3.6 (40 6) b 480 380 1. 0 2.0 (10 1) b 1. 0 (18 2) c 37 0.02 (0. 21 0.08) 4.4 350 600 17 16 c a Metal ... Mnặoxalacetate ẳ 1. 2 ã 10 )2 M [14 ], Mnặoxalate ẳ 1. 78 ã 10 )4 M, Mgặoxalate ẳ 4 .17 ã 10 )3 M [15 ] MnATP2 ẳ 1. 5 ã 10 )5 M, MnHATP ẳ 2.2 ã 10 )3 M, MgATP2 ẳ 6.3 ã 10 )5 M, MgHATP ẳ 4.8 ã 10 )3 M, MnADP ẳ 8 .1 ã 10 )5...

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Báo cáo khoa học: Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein–protein interactions pptx

Ngày tải lên : 07/03/2014, 10:20

... obtain sN ¼ Nðr À 1 ðrN 1 þ 1 À 2rðrN À 1 bPT =Q ðr À 1 2 ðrN 1 À 1 HN HN ¼ sN ¼ bPT =Q þ r a þ b 15 10 N =1 B where 10 10 0 Random b1 13 Þ 0 .1 Stimulus strength, KT /PT 12 Þ so that the transition ... bn ¼ [in (A)]; a1 ¼ bN ¼ 0. 01, an ¼ (n „ 1) , bn ¼ (n „ N) [in (B)]; N ¼ 4, L0 ¼ L1 ¼ ¼ LN ) ¼ 0 .1, QN ¼ QN ) ¼ ¼ Q1 ¼ 0 .1 [in (A–B)] 10 54 FEBS Journal 274 (2007) 10 46 10 61 ª 2007 The Authors ... mechanism and N! for the random mechanism 10 48 dY0 ¼ Àa1 Y0 þ b1 Y1 dt dYn ¼ an Yn 1 À ðan 1 þ bn ÞYn dt þ bn 1 Yn 1 ; for n dYN ¼ aN YN 1 À bN YN dt ð2aÞ ð2bÞ N 1 ð2cÞ where an and bn are effective...

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Báo cáo khoa học: Supramolecular calsequestrin complex Protein–protein interactions in chronic low-frequency stimulated muscle, postnatal development and ageing pot

Ngày tải lên : 08/03/2014, 10:20

... muscle Anal Biochem 299, 268–2 71 13 Pette, D (20 01) Historical Perspectives: plasticity of mammalian skeletal muscle J Appl Physiol 90, 11 19 11 24 14 Hauschka, S.A (19 94) The embryonic origin of ... Jones, L.R (19 90) Intralumenal sarcoplasmic reticulum Ca2+-binding proteins Sem Cell Biol 1, 265–275 10 MacLennan, D.H & Reithmeier, R.A (19 98) Ion tamers Nat Struct Biol 5, 409– 411 11 Donoso, ... & Hidalgo, C (19 96) Luminal pH regulated calcium release kinetics in sarcoplasmic reticulum vesicles Biochemistry 35, 13 419 13 425 12 Glover, L., Froemming, G & Ohlendieck, K (20 01) Calsequestrin...

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Báo cáo khoa học: Biochemical properties of the human guanylate binding protein 5 and a tumor-speciﬁc truncated splice variant Mark Wehner and Christian Herrmann doc

Ngày tải lên : 15/03/2014, 10:20

... (kcalÆmol )1) TÆDS (kcalÆmol )1) 7.2 ± 0.3 2.6 ± 0.3 15 ± )14 .7 ± 0 .1 ) 31. 3 ± 0.4 ) 21. 4 ± 0.8 )7.7 ± 0.2 )23.5 ± 0.6 )14 .9 ± 0.9 11 ± ± 0.2 26 ± )16 .5 ± 0 .1 )25.3 ± 0.3 )38 .1 ± 0.8 )9.7 ± 0.2 )18 .2 ... 0.5 0 .19 ± 0.02b 1. 9 ± 0.3 mant-GTP 0. 014 ± 0.0 01 0.62 ± 0. 01 – 44 ± 4* hGBP5ta mant-GDP 0.066 ± 0.004 0 .13 ± 0. 01 0.23 ± 0. 01 3.5 ± 0.3 mant-GTPcS 0.072 ± 0.006 1. 4 ± 0 .1 1 .15 ± 0.05a 16 ± 0.20 ... lm )1 s )1) and mant-GTP (0. 014 lm )1 s )1) were quite similar In contrast, we found a ﬁve-fold faster dissociation of mant-GTPcS (1. 11 s )1) compared to mant-GDP (0.23 s )1) and mant-GTP (0.62 s )1) ...

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Báo cáo Y học: Transcriptional activity of interferon regulatory factor (IRF)-3 depends on multiple protein–protein interactions pdf

Ngày tải lên : 17/03/2014, 10:20

... (19 98) Structure and Function of Ó FEBS 2002 10 11 12 13 14 15 16 17 18 19 20 21 22 Mechanism of IRF-3 virus-dependent activation (Eur J Biochem 269) 615 1 the Interferon-b Enhanceosome Cold Spring ... presence of cotransfected p300 (1. 5 lg), WT or the indicated mutants, schematically represented in (F), DNR (D3 17 3), DBromo (D10 71 12 41) , DE1a (D1739 18 71) , DSRC (D2042– 215 7) [27] reduced transcriptional ... with GST-CBP1 )11 00, GST-CBP1892)24 41 or their combination did not result in any activation of the ISRE · 3CAT reporter (Fig 6B) The inability of GST-CBP1 )11 00 and GST-CBP1892)24 41, alone or in...

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Báo cáo khoa học: HIP/PAP, a C-type lectin overexpressed in hepatocellular carcinoma, binds the RIIa regulatory subunit of cAMP-dependent protein kinase and alters the cAMP-dependent protein kinase signalling ppt

Ngày tải lên : 23/03/2014, 13:20

... Ó FEBS 2004 10 11 12 13 14 15 16 17 18 19 the mammary gland of lactating transgenic mice Secretion into the milk and puriﬁcation of the HIP/PAP lectin Eur J Biochem 267, 16 65 16 71 Christa, L., ... before 10 lM brefeldin A was added to the culture medium At the end of incubation, cells lysed in buffer A (10 mM KH2PO4 pH 7.4, 15 0 mM NaCl, 10 mM EDTA, 1% (v/v) Triton X -10 0 and lgÆmL )1 aprotinin, ... kgt 11 DNA puriﬁcation kit (Stratagene) Chang cells (CCL13, ATCC) seeded in 10 0 mm Petri dish were maintained in DMEM supplemented with 7% (v/v) fetal bovine serum, 10 0 lgÆmL )1 streptomycin and 10 0...

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Báo cáo khoa học: Calcium-dependent protein–protein interactions induce changes in proximity relationships of Cys48 and Cys64 in chicken skeletal troponin I ppt

Ngày tải lên : 23/03/2014, 21:20

... Densitometric pCa ± ± ± ± ± ± 3.83 17 .63 5.23 3.23 2.22 2.86 286.37 11 0.42 303.83 277.25 3 01. 18 10 2.35 ± ± ± ± ± ± 22.0 15 .7 11 .32 14 . 01 1.73 12 .53 Fig Changes in monomer and excimer ﬂuorescence of (A) ... Gergely, J (19 81) Proteolytic fragments of troponin C Interactions with the other troponin subunits and biological activity J Biol Chem 256, 13 1 21 13 127 41 Pearlstone, J.R & Smillie, L.B (19 78) Troponin ... 2549–2555 16 Hitchcock, S.E., Zimmerman, C.J & Smakkey, C (19 81) Study of the structure of troponin-T by measuring the relative reactivities of lysines with acetic anhydride J Mol Biol 14 7, 12 5 15 1 17 ...

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Báo cáo khoa học: Structural and mutational analyses of protein–protein interactions between transthyretin and retinol-binding protein doc

Ngày tải lên : 30/03/2014, 02:20

... chain F R 16 3 Q164 Y165 R166 Q149 K150 Q156 R163 L167 a Fab chain L a Fab chain H a F36, S95 , Y100 N34a, R54b R54b Y53, R54a, N57a Y103 F1 01, Y52, T30b, S31b D55b D102a D102b,Y103a Y103b An H-bond ... variant Y 114 H TTR variant 13 058 334 ⁄ 42 17 65 16 5 ⁄ 17 83 94 0.239 (0. 313 ) 0. 312 (0.357) 37.5 13 .4 0.209 (0.277) 0.229 (0.303) 17 .8 – 0. 218 (0.258) 0.2 81 (0.326) 23.3 – 0. 010 1. 5 0. 011 1. 29 0.006 1. 3 ... Y 114 H TTR variant C222, a = 15 9.62, b = 223 .18 , c = 12 1.43 15 .72–3.36 (3. 51 3.36) 25746 (16 22) 3.0 (2.6) 84.4 (77.7) 3.3 (1. 9) 0 .16 (0.34) P 212 12, a = 42.00 b = 83. 81, c = 65.58 65.5 1. 59 (1. 63 1. 59)...

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dna–protein interactions principles and protocols second edition - tom moss

Ngày tải lên : 08/04/2014, 12:51

... 2000 12 0 Eicosanoid Protocols, edited by Elias A Lianos, 19 99 11 9 Chromatin Protocols, edited by Peter B Becker, 19 99 11 8 RNAProtein Interaction Protocols, edited by Susan R Haynes, 19 99 11 7 Electron ... interactions Electrophoresis 19 , 12 4 712 53 Cann, J R (19 98) Theoretical studies on the mobility-shift assay of proteinDNA complexes Electrophoresis 19 , 12 714 1 Cann, J R (19 89) Phenomenological theory ... J Vogel, 20 01 172 Calcium-Binding Protein Protocols, Volume 1: Reviews and Case Histories, edited by Hans J Vogel, 20 01 1 71 Proteoglycan Protocols, edited by Renato V Iozzo, 20 01 170 DNA Arrays:...

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Báo cáo hóa học: " Viable chimaeric viruses confirm the biological importance of sequence specific maize streak virus movement protein and coat protein interactions" pdf

Ngày tải lên : 20/06/2014, 01:20

... [http://www.biomedcentral.com/content/supplementary /17 43422X-5- 61- S3.ppt] 10 11 12 13 14 15 16 17 18 19 20 21 Briddon RW, Pinner MS, Stanley J, Markham PG: Geminivirus coat protein gene replacement alters insect specificity Virology 19 90, 17 7:85-94 ... http://www.virologyj.com/content/5 /1/ 61 lar quantities of the purified fragments from pKNco and pSNco, using the following combinations of fragments: 1) S1, K2, K3; 2) K1, S2, K3; 3) S1, S2, K3; 4) K1, S2, S3; 5) S1, K2, ... Page of 11 (page number not for citation purposes) Virology Journal 2008, 5: 61 http://www.virologyj.com/content/5 /1/ 61 % Plants infected A 10 0 KNco 80 K-MP-S 60 K-CP-S 40 K-MP-CP-S 20 0 10 15 20...

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Báo cáo hóa học: " Towards Inferring Protein Interactions: Challenges and Solutions" ppt

Ngày tải lên : 22/06/2014, 23:20

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