molecular signatures of bladder cancer
Molecular signatures of gastric cancer an integrated approach to molecular cytogenetics, whole genome copy number and transcriptome profiles
... Table of contents Contents TITLE PAGE i ACKNOWLEDGEMENTS ii TABLE OF CONTENT iv SUMMARY vii LIST OF TABLES xi LIST OF FIGURES xiii LIST OF ABBREVIATIONS xx REVIEW OF THE LITERATURE Gastric cancer ... karyotyping of seventeen gastric cancer cell lines 7.1 Gastric cancer spectral karyotypes 7.2 148 Recurrent patterns of translocations Multimodality whole genome characterization of gastric cancer ... gastric cancers 13 Molecular characterization of 18q21q22 breakpoint genes 284 13.1 mRNA expression profiling 13.2 Expression of breakpoint genes by immunohistochemical staining v Table of contents...
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molecular biology of human cancers an advanced student's textbook - wolfgang a. schulz
... cloning of tumor suppressor genes in hereditary cancers 288 14 Bladder Cancer 289 14.1 Histology and etiology of bladder cancer 290 14.2 Molecular alterations in invasive bladder ... evolving scope of molecular diagnostics 427 21.2 Molecular diagnosis of hematological cancers 429 21.3 Molecular detection of carcinomas 433 21.4 Molecular classification of carcinomas ... left blank MOLECULAR BIOLOGY OF HUMAN CANCERS This page intentionally left blank Molecular Biology of Human Cancers An Advanced Student’s Textbook by WOLFGANG ARTHUR SCHULZ Department of Urology...
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Báo cáo hóa học: " Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies" pptx
... results of result of gene expression profiling Jin et al Journal of Translational Medicine 2010, 8:4 http://www.translational-medicine.com/content/8/1/4 Page of 15 Figure Change in the expression of ... analysis of maturing DCs revealed two distinct patterns: down-regulation of groups of miR at hours of maturation with sustained low expression throughout the rest of maturation and up-regulation of ... Marincola FM: Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness Cancer Res 2002, 62:3581-3586 Jin et al Journal of Translational Medicine 2010,...
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báo cáo hóa học:" The psychological context of quality of life: a psychometric analysis of a novel idiographic measure of bladder cancer patients’ personal goals and concerns prior to surgery" pot
... used bladder cancer disease specific instruments only, five used general instruments only (not specific to bladder cancer) , and five studies used a combination However, only one of the bladder cancer ... included examination of patient characteristics and quality of life, thematic content coding of responses to the Brief Quality of Life Appraisal Profile, examination of the relationship of goal attainment ... idiographic measure of quality of life Analysis of the Construct Validity of the Brief QOL Appraisal Profile A key concept we used to examine the psychometric properties of the Appraisal Profile is construct...
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Báo cáo y học: "The molecular basis of lung cancer: molecular abnormalities and therapeutic implications" potx
... Tissue microarrays (TMAs) of lung cancer Tissue microarrays (TMAs) of lung cancer TMAs are comprised of core biopsies of 0.6 mm in diameter of different tumors and of uninvolved lung from the ... [98] of patients with or without cancer We recently acquired experience in this method for profiling of proteins in cancer tissue [99] We applied MALDI-MS to 79 surgically resected lung cancers ... exposure of the whole airway mucosa to tobacco smoke could cause the entire bronchial tree to be at increased risk of developing lung cancer, leading to the concept of field cancerization Field cancerization...
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Immunotherapy of bladder cancer
... 1.1 Bladder cancer 1.1.1 Epidemiology of bladder cancer Overview Bladder cancer is the most common cancer of the urinary tract According to WHO statistics for 2000, bladder cancer is the ... for bladder cancer and probably accounts for 50% of bladder cancer cases diagnosed in the United States It is estimated that smokers’ risk of bladder cancer may be up to three times that of non-smokers ... the treatment of superficial bladder cancer From the clinical point of view, therefore, therapeutic targeting of superficial bladder cancers in an in vivo model of liposome-mediated bladder- directed...
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Tài liệu Report on The Management of Non-Muscle-Invasive Bladder Cancer ppt
... Randone D Molecular epidemiology of bladder cancer: known chemical causes of bladder cancer: occupation and smoking Urol Oncol 1995;1:137 Wingo PA, Tong T, Bolden S Cancer statistics, 1995 CA Cancer ... Transurethral resection of bladder cancer Atlas of Urol Clin NA 1997;5:1 Silverman DT, Levin LI, Hoover RN Occupational risks of bladder cancer in the United States: II Nonwhite men J Nat Cancer Inst 1989;81:1480-3 ... management of non-muscle-invasive bladder cancer (stages Ta, T1 and Tis) Methodology To develop recommendations for treatment of non-muscle-invasive bladder cancer, the AUA Bladder Cancer Clinical...
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Tài liệu MULTICOLOR QUANTUM DOTS FOR MOLECULAR DIAGNOSTICS OF CANCER doc
... Prostate-specific antigen: a review of the validation of the most commonly used cancer biomarker Cancer 101(5), 894–904 (2004) 30 Goessl C Noninvasive molecular detection of cancer – the bench and the ... progress of Q as clinical labels Ds References Papers of special note have been highlighted as: • of interest • of considerable interest • Jemal A, Murray T, Ward E et al Cancer statistics, 2005 CA Cancer ... sections of tumor biopsies is not simple due to the high autofluorescence and the loss of antigen presentation associated with the Figure Molecular imaging of cells and tissues (A) 3D imaging of intracellular...
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Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx
... associated with stimulation of ERK1 ⁄ and Pak1 pathways, gefitinib might lead to inhibition of invasiveness of human cancer cells through the inhibition of ERK1 ⁄ and Pak1 The use of gefitinib in cells ... level of Bcl-2 family genes and the phosphorylation state of their proteins, thereby changing the amount and localization of Bcl-2 family members However, each type of cancer has its own way of ... [23] Regulation of Bcl-2 family members can occur by a number of mechanisms, including up-regulation of synthesis, enhancement of degradation and phosphorylation In the event that cancer cells undergo...
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Classification of colorectal cancer based on correlation of clinical, morphological and molecular features doc
... aggressive subset of colorectal cancer Br J Cancer 2001; 84; 232–236 69 Goel A, Arnold CN, Niedzwiecki D et al Characterization of sporadic colon cancer by patterns of genomic instability Cancer Res ... A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer J Pathol 1998; 184; 148–152 21 Grady WM, Rajput A, Myeroff L et al Mutation of the type II ... al Loss of IGF2 imprinting: a potential marker of colorectal cancer risk Science 2003; 299; 1753–1755 107 Kruhoffer M, Jensen JL, Laiho P et al Gene expression signatures for colorectal cancer...
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A gene expression database for the molecular pharmacology of cancer pptx
... sensitivity signatures of melanotic melanoma, but derived from a pleural effusion of a patient with breast cancer Relationship of drug-activity patterns to mechanism of action Most of the compounds ... were to understand molecular pharmacology, to aid in the process of drug discovery and to provide a rationale for selection of therapy on the basis of molecular characteristics of a patient’s tumour ... cancer NCIH226; colon cancer COLO 205; CNS cancer SNB-19; melanoma LOX-IMVI; ovarian cancers OVCAR-3 and OVCAR–4; renal cancer CAKI-1; prostate cancer PC-3; and breast cancers MCF7 and HS 578T...
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molecular analysis of cancer - carrie fidler
... Overview of Molecular Cancer Genetics 1 Molecular Analysis of Cancer An Overview Ken Mills Introduction Cancer is a complex disease occurring as a result of a progressive accumulation of genetic ... assessment of prognosis and disease progression The aim of Molecular Analysis of Cancer is to provide a comprehensive collection of the most up-to-date techniques for the detection of molecular ... and telomerase levels, an area of extensive study in the field of cancer research We wish to thank the authors of the various chapters of Molecular Analysis of Cancer for their excellent contributions...
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báo cáo hóa học:" Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer" pdf
... Estimation of the performance of classification of breast canEstimation of the performance of classification of breast cancer samples A – The total error rate was plotted against the number of features ... detection of certain less abundant peptides in the presence of albumin [49] Figure between sub-groups of breast cancers patients Estimation of differences of serum proteome patterns Estimation of differences ... (SELDI) coupled to a Time -of- Flight (ToF) analyzer, which combine high throughput, fair sensitivity and accuracy of annotation of m/z values of ions in recorded mass spectra of complex protein mixtures...
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Báo cáo hóa học: " The application of adjuvant autologous antravesical macrophage cell therapy vs. BCG in non-muscle invasive bladder cancer: a multicenter, randomized trial" pptx
... urothelial carcinoma of the bladder: risk factors define feasibility of bladdersparing approach? Eur Urol 2008, 53(1):146-52 Witjes JA: Management of BCG failures in superficial bladder cancer: a review ... immunologically active components of bacille Calmette-Guérin in therapy of superficial bladder cancer? Int J Cancer 2000, 87(6):844-52 11 Luo Y, Yamada H, Evanoff DP, Chen X: Role of Th1-stimulating cytokines ... Urothelial Carcinoma of the Bladder Eur Urol 2008, 54(2):303-14 Witjes JA, Hendricksen K: Intravesical pharmacotherapy for non-muscleinvasive bladder cancer: a critical analysis of currently available...
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Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx
... investigation of the biology and therapy of bladder cancer than subcutaneous implantation of bladder cancer cells (heterotopic model) Therefore, a mouse model was developed by intravesical instillation of ... growth inhibition of orthotopic bladder tumors by the double promoter vector Transurethral implantation of human bladder cancer cells into the mouse bladder (orthotopic model) Page of 18 provides ... a variety of tumors including bladder carcinoma, hepatocellular carcinoma, breast cancer, ovarian cancer and prostate cancer [19-22] The human H19 gene lies within 200 kb downstream of the paternally...
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Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
... copies in >90% of cells ≤2 copies in ≥40% of cells, copies in 10%–40% of the cells, ≥4 copies in
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báo cáo khoa học: "The association of fish consumption with bladder cancer risk: A meta-analysis" ppsx
... http://www.wjso.com/content/9/1/107 Page of Figure Process of study selection for fish consumption and risk of bladder cancer included more than 200 cases of bladder cancer were defined as “large”, and ... estimating the association between fish consumption and risk of bladder cancer Figure Funnel plot of fish consumption and bladder cancer risk concerns about mercury and other environmental impurities ... in part by Li et al World Journal of Surgical Oncology 2011, 9:107 http://www.wjso.com/content/9/1/107 Page of Table Summary of pooled risk ratios of bladder cancer for fish consumer by study...
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báo cáo khoa học: " Overexpression of Pim-1 in bladder cancer" pdf
... understand of the clinical significance of Pim-1 Figure Expression profile of Pim-1 in bladder cancer cell lines A Expression profile of Pim-1 in bladder cancer cell lines Cell lysate from five bladder ... associated with bladder cancer initiation and progression Expression profile of Pim-1 in bladder cancer cell lines In order to further demonstrate the role and function of Pim-1 in bladder cancer, the ... Overexpression of Pim-1 in human bladder cancer specimens Pim-1 is overexpressed in both cytoplasm and nucleus of bladder cancer cells Normal bladder epithelium cells show no or minimal staining (A&D) Bladder...
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báo cáo khoa học: "The potential benefits of low-molecular-weight heparins in cancer patients" ppsx
... deregulation of these factors is observed in cancer patients, resulting in disruptions to the normal process of clot lysis [25] Cancer patients may, therefore, possess abnormal expression of a number of ... increased risk of VTE, they are also at an increased risk of bleeding [30,31] Given that the risk of VTE outweighs the risk of bleeding in most cancer patients [30,31], the use of antithrombotic ... long-term anticoagulation in cancer patients [1,16-19] However, despite the existence of these guidelines and the high-risk of VTE in cancer patients, up to 75% of cancer patients not receive...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25