... of malignant melanocytes within the basal layer ofthe epidermis, giving rise to the term “lentiginous” The term “acral” defines the location which is ofthe extremities, namely the skin ofthe ... modification ofthe ABCD rule developed for detection of suspicious pigmented lesions on the skin and applied it to the nail unit [39] First is A for Age, in the 5th to 7th decade of life B stands for ... stands forthe Digit most commonly involved, which forthe foot would be the big toe E stands for Extension ofthe pigment onto the adjacent skin or nail fold, known also as Hutchinson’s sign and...
... arm in the monosaccharide binding site [34] The conformation ofthe GlcNAcb(1–2)Man entity occupying the )1 and M subsites of LOL roughly resembles the conformation seen in the NA2F complex of PAL ... energetically favorable and contributes significantly to the higher affinity of PAL forthe pentasaccharide M592 (Table 3) In the case of A on the other hand, binding of GlcNAc to the )1 subsite does ... complexes [34] Therefore, we conclude that the reason forthe difference in energetics ofthe )1 subsite between PAL and A must be due to details in the interaction between the protein andthe carbohydrate...
... Although the last two articles were not published at the time of Sawers and Stillwaggon’s review, they render obsolete the critiques ofthemodelling work that might have remained after all ofthe other ... Cassels andthe two anonymous reviewers for their valuable feedback and assistance with the manuscript Authors’ contributions SMG is responsible for all aspects ofthe manuscript and has read and ... to the extinction ofthe HIV epidemic The final work [27] is the first to include a model in which both the partnership timing and networks andthe biology are fully driven by empirical data, and...
... forthe LE group andthe three other raters forthe OC group Forthe comparison between the automatic speech recognition system andthe expert ratings, the mean rating of all human raters was ... treatment for oral cancer As a precondition forthe evaluation ofthe patient groups, the extent of disorder is widespread, as seen by the results ofthe perceptual assessment andthe ASR results The ... technique for diagnostics to quantify the influence of altered speech and voice on therecognition results in stable ASR conditions The quality oftherecognition allows assessing the quality of the...
... Institute) forthe use of their thermocycler, and Lionel Saunois for technical assistance This work is a part ofthe Ph.D thesis of PRG financed by the French MENRT andthe French Institute for Biodiversity ... good example of a mixed population 3.2 Seed characteristics The percentages of germination obtained for populations ofthe two species and from the zone of sympatry (Tab II) reinforced the results ... phenotypes (00 and 11) and explained only 16.32% ofthe observed variation (Fig 1) The populations from the zone of sympatry were distributed between the two groups, andthe population of St-Dyé (S5)...
... in the US and Europe, those standards are under continued review as science and practice evolve The globalization of standards creates a challenge for those standards andfor feedback onto standards ... participants understand or remember about the consent process [16] Judgment about the appropriate level of effort to achieve informed consent hinges on the risks and benefits ofthe survey For example, ... constraints ofthe field research The primary concern in the US and other developed countries is that survey data is not used to disclose the identity of an individual Linkage of data systems and profiling...
... month ofthe year exceeds the maximum ofthe other years 136 Figure 6.6 The cumulative amount by which the horizontal global radiation for each month ofthe year falls below the minimum ofthe ... the minimum ofthe other years 134 Figure 6.2 The number of hourly instances that the horizontal global radiation for each month ofthe year exceeds the maximum or falls below the minimum of ... reviews the evolution ofsimulation methods for building performance prediction and current status of facade design studies and thermal comfort criteria for hot-humid climate, highlights the advantages...
... is the range ofthe amorphous Pearson profile Rpb is the range ofthe channeled Pearson profile σ a is the standard deviation ofthe amorphous Pearson profile σ b is the standard deviation ofthe ... channeled and amorphous Pearson profiles, respectively, ratio is the ratio ofthe dose ofthe amorphous profile to the total dose and u is the coordinate along the depth A final profile will take the ... channeled Pearson profile γ a is the skewness ofthe amorphous Pearson profile γ b is the skewness ofthe channeled Pearson profile β a is the kurtosis ofthe amorphous Pearson profile - 28 - b β...
... homogeneous theory for periodic materials with andthe assumptions forthe application ofthe FEM which runs on the open source code ofthe program CAST3M (France) Results are calculated for a specific ... confirming the reliability ofthe method The drawback ofthe method is calculated primarily for periodic materials For materials with randomly arranged forms such as random spheres mentioned in the ... convergence in the case of three-phase, also three-point correlation parameters ofthe material has considered The results are the same between the upper and lower bounds, a new contribution ofthe thesis...
... users andthe performance characteristics ofthe effectiveness algorithm between biologic and DMARD treatment episodes, the data were shown throughout forthe biologic users as a unique group, and ... sensitivity and specificity, unlike PPV and NPV, should be less dependent on the prevalence in the population, and more reflective ofthe test itself, lessening the impact of any unique features ofthe ... used only to capture the DAS28, the CDAI and other clinical characteristics measured at the baseline and outcome VARA visits; all other data used forthe analysis were from the administrative claims...
... orally [27] Therefore, the aim ofthe present study was to evaluate the inhibitory effect of some thioglycosides synthesized in our laboratory on human hSGLT1 and hSGLT2 –as a potential therapeutic ... system, in the distal segment ofthe tubule Inhibition of glucose reabsorption in the kidney, mediated by the SGLT cotransport system, represents a promising therapeutic target forthe control of hyperglycemia ... hydrolysis-resistant, synthetic S-analogs of natural O-glucosides involved in the biosynthesis of chrysomelidial and salicin These substances are synthesized and secreted as part of a defense mechanism...
... supported by the research project The research on the development ofthe total evaluation technique forthe hazardous impacts by the chemical substances towards human and ecology (the project ... C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products ofthe in vivo reaction of N-hydroxy-6-aminochrysene with DNA andthe formation ofthe adducts in isolated rat ... recommend the Ames test using these sensitive strains (especially YG1041 and/ or YG1042) in combination with the standard tester strains (TA98 and TA100 series), in order to detect the mutagenicity of...
... know the benefit of having the connection of their latrines to biogas plants At the installation, the community agreed to share the 20% ofthe installation cost andthe 100% of cleaning cost of ... because the people were involved from the beginning ofthe installation and they understood the benefit ofthe option from the combination of hygiene education and their experience from the test ... addition, they agreed to bear 100% ofthe cost ofthe cleaning ofthe connection system such as pipes and connection pits in the case of blockage At this stage, the regular maintenance and cleaning of...
... instar larvae and 3-day old pupae were used The main component of one ofthe oils was pulegone andofthe other is not yet totally identified, and it is called SEM76 In space fumigation, these two ... were found to be the most potent fumigants of all oils tested The main component of one ofthe oils is pulegone The other is not yet identified and it is called SEM76 (Shaaya and Kostyukovsky, ... 2002) ITCs were chosen for this study because ofthe pesticidal properties of these chemicals (Fenwick at al., 1983) and because ofthe potential use of methyl ITC as fumigant for wheat (Ducom, 1994)...
... kinetics and use of nonthermal alternative processes.31 Most notably, as a part ofthe Þve-year contract between the Institute of Food Technologists (IFT) andthe FDA, a scientiÞc review of these ... 90% of their energy at a wavelength of 253.7 nanometers Exposure of bacteria to UV results in cross-linking ofthe thymine dimers ofthe DNA in the organism, preventing repair of injury and reproduction ... postharvest handling, washing, and cooling and storage PREVENTIVE MEASURES IN THE ORCHARD Contamination of fruits with feces of animals such as deer,8 seagulls,9 and cattle and other ruminants10 in the...
... implanted forthe relief of severe lower limb spasticity and flexor spasms The goals then are improved comfort and wheelchair posture, Intrathecal baclofen forthe control of spinal and supraspinal ... the process of consideration for ITB Patients may hear about ITB and discuss the question with their therapists rather than their doctors The charting of range and function before and after a ... cord than in the brain because ofthe characteristics ofthe circulation ofthe CSF from the ventricles to the spinal subarachnoid space The effective distribution volume of intrathecally administered...
... The last ofthe four kinds of parts is found in the center ofthe flower, and is called the pistil It is this part which forms the fruit and incloses the seed The stamens andthe pistil are the ... other time ofthe year The plan of branching, the position, number, size, form, color, and surface of buds, as well as the arrangement ofthe leaves within the bud andthe peculiarities ofthe scales ... plants themselves This chapter therefore will be devoted mainly to the words needed for leaf description, together with their application The Leaf.—In the axil ofthe whole leaf the bud forms for the...
... report by the Netherlands Institute for Public Health andthe Environment, RIVM, examined unfavourable dietary composition and health loss One ofthe conclusions is that an excessive intake ofthe ... fora at national level At the same time, the Platform can create input for integrating the responses to the obesity challenge into a wide range of EU policies The Commission regards the Platform ... Transport and urban planning policies can ensure that walking, cycling and other forms of exercise are easy and safe, and address non-motorised modes of transportation The provision of safe cycling and...
... and both deal with prescriptions for improving the quality of life The differences are between perspectives: the individual andthe societal; the negative andthe positive; the curative andthe ... decisions based on their own or their children’s diagnosis, 3) Understand and respond to informed consent forms, 4) Understand medication instructions for themselves and their children, and 5) Be knowledgeable ... which the client/family is at the center and controls the flow of information The educator asks questions and listens thereby allowing the client/family to lead the discussion based on their...
... from data in the RCT The survival of patients receiving ASC/BSC was calculated from the survival ofthe patients in the cetuximab monotherapy arm ofthe RCT The data from the monotherapy arm NICE ... guide for healthcare professionals Information for people with metastatic colorectal cancer and their carers (‘Understanding NICE guidance’) Details of all the evidence that was looked at and other ... evidence from the bevacizumab studies and noted that the age ofthe population in the largest study was lower than the age of patients normally receiving chemotherapy in England and Wales However,...