... A (1979) Involvement of
histone H1 in the organization of the nucleosome and
of the salt-dependent superstructures of chromatin.
J Cell Biol 83, 403–427.
Active chromatin and DNase I hypersensitive ... with
binding of both MOF and Tip60 (equivalent to Esa1
in yeast NuA4) [124,130]. However, in human cells
depletion of MOF, but not Tip60, results in reduced
global levels of AcH4-K16 and defective ... acetylation and deacetyla-
tion, and transient recruitment of remodellers and
transcription factors.
A cycle of transcription commences with the recruit-
ment of transcription factors and co-factors...
... to T hr49) and TmAFP (blue, residues
Asn29fiGly41). Letters de note the five residues of on e of the three
sides of s bwAFP o r s ix residues of on e of two sides of T mAFP. T he
strands that make ... Overlap of
X-ray structure with 5 °C NMR structure using the main chain of
residues Ser12 fiThr70 in t he structure a lignment. (B) O verlap of the
X-ray structure with the 30 °C NMR structure ... [31,32,36] and their three-
dimensional structures were determined [34,37–40]. In
subsequent sections, we describe the structureand dynamics
of each protein, and present a comparison of s bwAFP and
TmAFPwitheachotherandwithproteinsthathavea
similar...
... model of the
role of point of view in problem solving.
SUMMARY
We have reported here a three
pronged approach to
the study of problem solving action and report: I) the
collected of data ... of data on problem solving and talk about
problem solving, 2) development of a process model of
these behaviors, and 3) use of coding techniques to
extract traces of "critical phenomena" ... efforts on two types of problem solving
phenomena: the changes in the problem solver's
organization of the problem ("point of view"), and
systematic multl-utterance structures used...
... minidomain and the zinc-binding domain
of the zinc finger protein Ynr046w [25] (Fig. 8). The fit
of the heavy atoms (Ca, C, and N) from three
b-strands and the a-helices of both the closed and the
open ... TA, Gargaro AR &
Feeney J (1999) Structureand dynamics in solution of
the complex of Lactobacillus casei dihydrofolate reduc-
NMR structureand function of the eRF1 C-domain A. B. Mantsyzov ... variation of pH in the range
between 6.3 and 7.7, of ionic strength between 25 and
100 mm NaCl andof temperature between 278 and
313 K did not lead to any detectable change in the
populations of the...
... helices A
V
and
B
V
at the surface of domain V. Gly621 and Gly617 are in the area of contact with the 1095 and 2473 regions of 23S RNA. The two helices
are facing the ribosome, and the four-stranded ... 666 and 670, within one b-strand of
domain V, are also important for interdomain interac-
tions. The N-terminal part of the strand interacts with
the N-terminal part of helix C
G
in domain G, and ... occupancy of GDP in the nucleotide-binding
site. Therefore, we present here the apo structure of
S. aureus EF-G.
Overall structureand comparison with previous
EF-G structures
All five domains of S....
... hypotheses and providing
proof of concept and statistical evidence for many of
them. Over the next few years, it will become essential
to investigate more of the details of the field, and
establish ... and
sequence, and this controls the topology of the final
structures and is related to the direction of the G-rich
strands making up the core.
Loops may link positions on the top (or bottom) of
the ... hybrid, with
three strands in one direction and one in the other,
and a mixture of loop types [14]. Which of these struc-
tures is preferred depends on the sequence and length
of the loops – in general,...
... surface potential of AFP (left) and PAF (right) structures representing the orientation of the side chain lysine resi-
dues. Lys9, Lys35 and Lys38 of PAF and Lys9, Lys32 and Arg35 of AFP are the ... of the adjacent Lys9 and
Lys39. Similarly, Asp23 stabilizes the juxtaposed
Lys15 and Lys17 side chains.
The hydrophobic strand b4 is located between Cys43
and Asp46 and, as a central strand of ... [14].
The 3D molecular structureof PAF consists of five
b-strands connected by three small loops involving
b-turn motifs (loops 1, 2 and 4) and the large loop 3
(Fig. 9). The b-strands create two orthogonally...
... different object in the same piece of memory. Either
way, the outcome of using dangling reference would be undefined. All bets would
be off.
•
You'd try and destroy the same object more ... runs in its own thread and can execute only at certain times
(typically when your application reaches the end of a method). While it runs, other
The Life and Times of an Object
First, let's ... tremendously useful and free you, the programmer, from tedious
housekeeping chores that are easy to get wrong. They allow you to concentrate on the
logic of the program itself and be more productive....
... many lower priced computers. By
the end of the 1980s most universities were making use of Unix computers in computer science
and engineering programs. This created a wealth of graduates who ... directories called ’.profile’ or ’.login’. These are used when a user logs.
Some of the standard Linux commands for files and directories are listed below. Most of the
file and directory names ... computers
Development - software authoring
2.1.5 Advantages and Disadvantages
A partial list of advantages and disadvantages is given below. The cost, stability and open
nature of the system have...