... prevalence of complications by time since the first diagnosis of diabetes, and the linear relationship between prevalence of complications and diabetes duration Results General characteristics of study ... significant impact of chronic complications on T2DM-related morbidity and mortality, and the Liu et al Health and Quality of Life Outcomes 2010, 8:62 http://www.hqlo.com/content/8/1/62 Page of Table 1: ... understanding the epidemiology of T2DM co-morbidities is of great importance Over the last two decades, there have been only a handful of small-scale studies dealing with the prevalence of chronic...
... mellitus High levels of free radicals and the decline of antioxidant defense mechanisms lead to damage of cellular organelles and enzymes, increased lipid peroxidation, anddevelopmentof insulin resistance ... and prevent further formation of excess free radicals Patients andmethods Electro Pressure Regeneration Therapy Device The EPRT device is an electrical device that sends a pulsating stream of ... Popliteal and pedal pulses were absent bilaterally with poor capillary refill The left foot was red and inflamed up to and including the medial malleolus The lateral aspect of the great toe and second...
... analyzed the prevalence of CD in Turkish children with T1DM and their non-diabetic first-degree relatives MATERIALS ANDMETHODS Patients and Control Subjects A total of 48 children with T1DM ... frequency of serologic test positivity in the relatives of diabetics was close to that of the control group and healthy Turkish children In children with T1DM, increased prevalence of CD is well documented ... (Table 1) The prevalence of seropositivity for CD was higher in patients with T1DM than their relatives (siblings and parents of diabetic children) and healthy controls (p=0.007 and 0.00005, respectively)...
... 24 months of follow-up Sample size For an alpha of 0.05, a power of 80%, and in order to detect an reduction of HbA1c of 0.3 percentage units, with a common standard deviation (SD) of 1.15, in ... the study in either of the two models analyzed, and the adjusted effect of PRECEDE was close to zero (Table 2) In both models, the level of exercise decreased Page of slightly and was not significant ... reduction of 7% in the risk of mortality owing to cardiovascular disease, and 10% in the risk of mortality owing to ictus with every mmHg decrease in SBP The slight decrease in the lipid profile of...
... the developmentof the research question, study planning, data analysis and drafting and revising the manuscript PO contributed to the study design, developmentof the research question and revising ... component of the National Institutes of Health (NIH), and NIH Roadmap for Medical Research Its contents are solely the responsibility of the authors and not necessarily represent the official view of ... with a mean of 50 and standard deviation of 10 in the general population [18,19] The SF-36 has been validated extensively as a measure of health status in people with chronic illness [2] and other...
... extraction and analysis, and drafted the manuscript FHR conceived of the study, and participated in its design and in the data extraction and analysis DdZ participated in the conception and design of ... populations andmethods We conducted analysis at this study level We present the type, median number and interquartile range (IQR) of ADEs at category level reported for the six different methodsof ADE ... of laboratory values and other methods [25-28] Studies using patient survey methods, medical record review, or laboratory data often included less than 300 patients (Figure 2) A sample size of...
... hypothesis of secondary mania due to a general medical condition The clinical efficacy of OXC, the 10-keto analogue of CBZ, in the treatment of acute mania and hypomania is reasonably well documented ... substantial contributions to conception and design of the present study, and in the acquisition of data AK made substantial contributions in the analysis and interpretation of the data He was also involved ... manuscript and revising it critically for intellectual content VM made substantial contributions to conception and design of the present study, and in the acquisition, analysis and interpretation of...
... excess in the number of deaths of Serraino et al AIDS Research and Therapy 2010, 7:11 http://www.aidsrestherapy.com/content/7/1/11 Page of Table 1: Standardized mortality ratios of dying from diabetes ... causes of death, we focused on acute myocardial infarction (ICD10, I21) and chronic ischemic heart diseases (ICD-10, I25), two important andwell diagnosed conditions Person-years (PY) at risk of ... non-Hodgkin lymphoma (14.6%), and Kaposi sarcoma (4.3%) (data not shown) DM and cardiovascular diseases were the underlying cause of death of 43 PWA (i.e., they cause 1.4% of all deaths): 14 deaths...
... breast Page of surgical approaches include the avoidance of sternal division, preservation of sternal stability, reduced blood loss and transfusions, reduced infection and hospitalizations, and avoidance ... approaches consist of partial sternotomy, right parasternotomy, right thoracotomy, and left thoracotomy With improvement of perioheral perfusion systems, use of these approaches is expanding all over ... echocardiography revealed mild mitral valve regurgitation and, mild pericardial effusion, and an ejection fraction of 68% In addition to improvement of clinical data, the patient was able to walk without...
... and DM subjects with and without sensation in both right hand and left hand Discussion Figure a Standard Division of foot area a Standard Division of foot area b Division of foot area for our ... study of the law of mobility to assess the sensibility of diabetic subjects, comparing the law of mobility of TPD in the upper and lower extremities of DM patients We observe that the law of mobility ... the graphs represent the mean value of TPD Normal and diabetic TPD for legs Figures and show TPD of normal and diabetic subjects for different areas of leg and foot from proximal to distal In...
... In this patient, the diagnosis of autoimmune thyroiditis was made on the basis of the presence of anti-thyroid peroxidase antibodies and the absence of evidence of another etiology for hyperthyroidism, ... University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195, USA 2Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington ... accompanying Page of images A copy of the written consent is available for review by the Editor-in-Chief of this journal Author details Division of General Internal Medicine, Department of Medicine,...
... hyperglycaemia, but the developmentof insulin resistance (a feature of MS and precursor to DM), increased levels of cholesterol and triglycerides, lipodystrophy, and the onset or complication of diabetes[18,60] ... undetected DM and IGT being present prior to the onset of TB It is well known that in most populations a large proportion of those with DM or intermediate hyperglycaemia are undiagnosed and only detected ... recent years there was a lack of good evidence on the strength and nature of the association between TB and DM At present recognition of the association between diabetes and TB is low The link goes...
... HJ, Heine RJ: Monitoring of psychological well- being in outpatients with diabetes: effect on mood, HbA1c, and the patient’s evaluationof the quality of diabetes care: a randomized controlled trial ... effects of the EDS, and higher risks of classification errors (e.g., [74]) Furthermore, removal of the items necessitates determining new cutoffs for diagnosing mild and severe levels of depression, ... explore and describe the measurement properties of the questionnaire and its constituent items One of the valuable features of IRT modeling is the possibility of evaluating the test and item...
... arterial pressure and the maximal rate of LV pressure developmentand relaxation (+dP/dt max and –dP/dt min) were unaffected by GLP-1 Reduction of CPP to 40 mmHg decreased stroke volume and cardiac ... settings of cardiac injury and failure However, there is a paucity of information regarding the acute cardiac effects of GLP-1 in patients with MetS and/ or T2DM Figure 1-2 Depiction of the classical ... effects of GLP-1 on coronary blood flow and vascular tone are unknown in humans and in the settings of MetS/T2DM Further studies to determine the effects of GLP-1 on coronary blood flow and vascular...
... meta-analysis of 41 randomized, controlled evaluations of metformin of at least 6-week duration showed significant reductions in total cholesterol, LDL cholesterol and triglycerides in patients randomized ... – MORE THAN ‘GOLD STANDARD’ IN THE TREATMENT OF TYPE DIABETES MELLITUS METFORMIN AND BODY WEIGHT METFORMIN AND LIPID PROFILE While insulin secretagogues, thiazolidinediones and insulin itself ... MORE THAN ‘GOLD STANDARD’ IN THE TREATMENT OF TYPE DIABETES MELLITUS DISCOVERY OF METFORMIN The work of Dr Jean Sterne, a French clinician and his colleagues led to the discovery of metformin as...
... survey of knowledge on diabetes in Thailand Pongmesa, Tipaporn Considering the impact of lifestyle on developmentof T2DM, this would signify a need for a re -evaluation of the effectiveness of public ... guidance and help I also cherish all my colleagues in S7 02-09, Yingjiao, Mandy, Hua Pey, Regine and Wei Ting, and my unit mates, Sureerat, Nichanan and Poonna, for their kind support and words of ... Conclusions…………………………………………………………………61 Chapter Developmentof a Thai Version of the Audit of Diabetes-Dependent Quality of Life (ADDQoL-19) Questionnaire: Linguistic and Psychometric Evaluation ………………………………………………………………………62...
... thanks and appreciation to Principal Laboratory Officers, Ms Ng Foong Har of the Department of Biochemistry and Ms Annie Hsu, of the Department of Pharmacology and Ms Boon Yoke Yin, Laboratory Officer, ... the office staff of the Department of Biochemistry and Pharmacology for their kindness and timely help I am grateful to the former Head, Prof Sit Kim Ping and the present Head, Prof Barry Halliwell, ... β-cell protective effect of AF and BuF…… 73 3.3 Results and discussion……………………………………………………… 75 Experiment 4: Evaluationof the anti-diabetic effects of AF and BuF in a rat model of type diabetes ……………………………………………………………………...
... from both the SDCS and NHS98 (Methods 2.1.1 and 2.1.2) and non-diabetic controls were from the NHS98 (Methods 2.1.2) 26 Chapter Materials & Methods CHAPTER 2: MATERIALS ANDMETHODS 2.1 Patient ... the brain, spinal cord and β-cells of the pancreas [45] In addition, expression of NPHS1 was detected in the testis, spleen and thymus [58] Cardiac expression in human fetaland mouse hearts was ... the urine of Finnish T1DM patients It was observed that 28% of macroalbuminuric, 17% of microalbuminuric and 30% of normoalbuminuric patients presented with nephrinuria while none of the nondiabetic...
... cent of babies born to HIV-infected women in Europe and America, and to 25–35 per cent of those born in Africa, India and Thailand (Peckham and Gibb, 1995; Newell et al., 1997) The majority of ... only understand the process of randomization, but also the risks and beneWts of treatment and non-treatment, and the treatments currently available The ACTG 076 regimen is expensive and relatively ... testing, and in the case of ‘routine’ voluntary named testing, consent is often vitiated by a lack of understanding and information, and sometimes by coercion The ethics of anonymised unlinked...
... Judgements of non-compliance in pregnancy of continuing their medication and risking the well- beingof their future child, or abstaining from its use for the duration of the pregnancy and seriously ... is necessary to understand the patient’s motives and life setting, the legitimacy of goals other than the pursuit of health, and the limits of individual physicians andof medicine more generally ... ways of managing the potentially complicated and dangerous Wnal stages of pregnancy – labour and delivery The timing, mode and location of delivery are all subject to strong medical advice and...