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measurements of vaccinia virus dissemination using whole body imaging approaches for predicting of lethality in challenge models and testing of vaccines and antiviral treatments

Báo cáo khoa học: Identification of sodium salicylate as an hsp inducer using a simple screening system for stress response modulators in mammalian cells pptx

Báo cáo khoa học: Identification of sodium salicylate as an hsp inducer using a simple screening system for stress response modulators in mammalian cells pptx

Báo cáo khoa học

... incubated for h in the presence of 50 lgÆmL)1 neutral red, and fixed with 1% formaldehyde containing 1% CaCl2 for The dye incorporated into viable cells was extracted with 50% ethanol containing 1% ... [20] The SAinduced form of HSF is not hyperphosphorylated like the heat-induced form, and SA-induced threonine phosphorylation of HSF, whereas heat shock led to a predominance of HSF serine phosphorylation ... instructions, and incubated for 48 h Cells were then maintained in DMEM containing 0.4 mgÆmL)1 G418 antibiotic reagent (Wako Pure Chemical, Osaka, Japan) for weeks, and C3H10T1/2 cell lines stably...
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Different physical and chemical pretreatments of wheat straw for enhanced biobutanol production in simultaneous saccharification and fermentation

Different physical and chemical pretreatments of wheat straw for enhanced biobutanol production in simultaneous saccharification and fermentation

Hóa học - Dầu khí

... Ontario and an MBA from Ryerson University, both in Canada He has worked for several years in the health care industry, mainly in the field of developing and testing of novel wound dressing materials ... eliminated Figure Comparison of sugar concentrations from soaking and no soaking process: (beside soaking and no soaking) represented glucose concentration and (beside soaking and no soaking) ... 2, 1.6 g of wheat straw was mixed in 50 ml of sterilized distilled water in 100 ml shaker flask and autoclaved at 135°C for h During Experiment and 4, 1.6 g of wheat straw in 50 ml of sterilized...
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In Vitro Screening of Plant Resources for Extra-Nutritional Attributes in Ruminants: Nuclear and Related Methodologies pptx

In Vitro Screening of Plant Resources for Extra-Nutritional Attributes in Ruminants: Nuclear and Related Methodologies pptx

Sức khỏe giới tính

... to the methods involved in collecting, preparing and screening plants for bioactive properties for use in manipulating key ruminal fermentation pathways and against gastrointestinal pathogens ... the initial screening is conducted in vitro because of the large number of candidate plant species and the prohibitive cost of screening them in vivo The number of species for in vivo testing ... emergence and wide-spread incidence of chemical residues in human food and antimicrobial and anthelmintic resistance causing a surge of interest in the use of “natural” alternatives to chemicals in...
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Báo cáo lâm nghiệp:

Báo cáo lâm nghiệp: "Evaluation of competition and light estimation indices for predicting diameter growth in mature boreal mixed forests" pdf

Báo cáo khoa học

... measures for predicting growth of individual trees, For Sci 35 (1989) 816– 831 [50] Vettenranta J., Distance-dependent models for predicting the development of mixed coniferous forests in Finland, ... Evaluation of some competition indices for the prediction of diameter increment in planted white spruce, Can For Serv Inf Rep FMR-X-108, 1978 [3] Bartelink H.H., Effects of stand composition and thinning ... Centres of Excellence in Sustainable Forest Management for funding this project, and the Alberta Ministry of Sustainable Resource Development, Land and Forest Division for providing access to their...
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báo cáo khoa học:

báo cáo khoa học: "State strategies of governance in biomedical innovation: aligning conceptual approaches for understanding ‘Rising Powers’ in the global context" pdf

Báo cáo khoa học

... science-based mapping of state -of- the-art analytic approaches to understanding of the state politics of innovation and governance applying to global biomedicine, and to the emerging global political ... multidirectional and a mixture of formal and informal structures in which the dynamics of governance are so intricate and overlapping among the several levels as to form a singular, web-like ... process shaping the emergence of new bio-objects, and in part being shaped Page 10 of 14 by technology innovation and potential markets (as well as being an external, steering and controlling force)...
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Báo cáo sinh học:

Báo cáo sinh học: "Divergent selection for humoral immune responsiveness in chickens: distribution and effects of major histocompatibility complex types" ppt

Báo cáo khoa học

... was maintained Every generation, there were ! 300 chicks each in the H and L lines and 250 chicks in the C line, from which r x 25 males and 50 females in the H and L lines and ;zz 40 males and ... al, 1979) in our H line (Pinard and Hepkema, 1992) Typing for MHC in lines of mice divergently selected for Ab response to SRBC (Biozzi et also revealed distinct haplotypes in the lines (Colombani ... effect of genotypes in a line was estimated by testing, jointly against the error variance term Q e, n independent differences between genotypes, with n being the number of genotypes in the line...
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Statistical learning approaches for predicting pharmacological properties of pharmaceutical agents

Statistical learning approaches for predicting pharmacological properties of pharmaceutical agents

Cao đẳng - Đại học

... 85 Figure 3.5 Binding of PXR activator hyperforin (in ball and stick) at PXR (in wire frame) ligand-binding site 86 Figure 4.1A and 4.1B Binding of agonist (E2) and antagonist (RAL) ... selected for the training set The remaining compounds for the training set were selected by maximizing the minimum distance between the compounds in the training set and the rest of the compounds in ... including TPT and non-TPT agents Finally, in the last chapter, Chapter 6, major findings and contributions of current work to the progress of using SLMs for predicting pharmacological properties of pharmaceutical...
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An investigation of fractiure criteria for predicting serface fracture in paste extrusion

An investigation of fractiure criteria for predicting serface fracture in paste extrusion

Tổng hợp

... substantial inelastic deformation forming Among those adopting this approach are Clift et al [4], Ko et al [5], and DeLo and Semiatin [6] The ÿrst of these is particularly extensive, investigating nine ... relationships of continuum mechanics are required For paste ows, as in metal forming, body forces are usually neglected; typical ow velocities are small enough for inertial e ects to be insigniÿcant, and ... strain is small Further information regarding the procedure can be found in Ref [18] and in more detail in Ref [19] Results: deforming zone stresses Pugh and Gunn [11], as reported by Pugh and...
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Báo cáo y học:

Báo cáo y học: "Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models" pot

Báo cáo khoa học

... pharmacokinetic profiles following ITZ administration Coupling of the previously established MDZ and ITZ models (a total of WB-PBPK models) finally facilitates Figure of tions of ITZ in relation ... curve (line)mg/kg MDZ Simulated plasma concentration time curve (line) of a) MDZ following a 15 minute intravenous infusion of 0.1 mg/kg MDZ and b) 1OH-MDZ following a 15 minute intravenous infusion ... dynamically links inhibitor and drug models using whole- body physiologically-based pharmacokinetic models (WB-PBPK) to quantify, under any administration time and dose regimen, the changes that occur in...
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Evaluation of Meteosat-8 measurements using daily global solar radiation for two stations in Iraq

Evaluation of Meteosat-8 measurements using daily global solar radiation for two stations in Iraq

Vật lý

... summery of Heliosat-2 can be explain by the following steps; recording the ground albedo maps for each month, computing the cloud index, calculating the clear sky index, and finally estimating the ... the procedure used in this work for evaluating of Meteosat-8 satellite measurements using ground measurements of the two Iraqi radiometric stations; Baghdad (33.33o N, 44.39o E) and Mosul (36.33o ... satellite measurements, which play an effective role in evaluating the real values of solar radiation reaching earth surface and that which estimated using Meteosat-8 images By comparing the results of...
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Tài liệu Báo cáo khoa học: PCR detection of nearly any dengue virus strain using a highly sensitive primer ‘cocktail’ ppt

Tài liệu Báo cáo khoa học: PCR detection of nearly any dengue virus strain using a highly sensitive primer ‘cocktail’ ppt

Báo cáo khoa học

... Similarly, virus isolation from infected sera is a time-consuming process requiring days of incubation followed by screening for the presence of virus [14] Nucleic acid-based assays offer rapid and ... missing 3.4% of 748 DENV-1, 0.5% of 568 DENV-2, 14.5% of 316 DENV-3 and 5.3% of 56 DENV-4 strains tested With reduced stringency, allowing one mismatch and one insertion per primer, 1675 of 1688 ... sensitivity for a broad range of dengue virus strains The predicted strain sensitivity of PCR using the cocktail described in this work was compared using e-PCR with the predicted sensitivities of some...
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Báo cáo sinh học:

Báo cáo sinh học: " Involvement of PKR and RNase L in translational control and induction of apoptosis after Hepatitis C polyprotein expression from a Vaccinia virus recombinant" doc

Điện - Điện tử

... production of infectious VV at 12, 24 and 48 h.p.i, in the presence or absence of the inductor IPTG As demonstrated in Figure by virus plaque formation and virus titration curves, the production of infectious ... cells infected in the absence of the inductor, or in cells inducibly expressing the VP3 protein (Figure 4A) The protein levels were quantified by densitometry of the bands and are represented in ... analysis of cellular and viral protein synthesis in cells expressing HCV polyprotein Time-course analysis of cellular and viral protein synthesis in cells expressing HCV polyprotein A: BSC40 cells infected...
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báo cáo hóa học:

báo cáo hóa học: "Whole-body isometric force/torque measurements for functional assessment in neuro-rehabilitation: platform design, development and verification" pot

Điện - Điện tử

... Journal of NeuroEngineering and Rehabilitation 2009, 6:38 Background One of the main scientific and technological challenges of rehabilitation bioengineering is the development of innovative ... daily instruments most widely used in the routine clinical practice In this work, our interest is focused on the development of mechatronic platform for the assessment of stroke patients using force/torque ... for days after 'Drinking': normalstroke onset (middle) hemiparetic patient, Force measurements fromsubject (top) ;and 131the task Force measurements from the index finger, for the task 'Drinking':...
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báo cáo hóa học:

báo cáo hóa học:" Involvement of PKR and RNase L in translational control and induction of apoptosis after Hepatitis C polyprotein expression from a Vaccinia virus recombinant" docx

Hóa học - Dầu khí

... production of infectious VV at 12, 24 and 48 h.p.i, in the presence or absence of the inductor IPTG As demonstrated in Figure by virus plaque formation and virus titration curves, the production of infectious ... cells infected in the absence of the inductor, or in cells inducibly expressing the VP3 protein (Figure 4A) The protein levels were quantified by densitometry of the bands and are represented in ... analysis of cellular and viral protein synthesis in cells expressing HCV polyprotein Time-course analysis of cellular and viral protein synthesis in cells expressing HCV polyprotein A: BSC40 cells infected...
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Báo cáo hóa học:

Báo cáo hóa học: "Research Article Analysis and Modelling of Muscles Motion during Whole Body Vibration" pdf

Hóa học - Dầu khí

... confirmed the meaning of a proper positioning in vibratory stimulus transmission Since WBV training is included in many fitness and rehabilitation centres exercise programmes, improvements in current ... Delecluse, S Swinnen, D Vanderschueren, and S Boonen, “Effect of 6-month whole body vibration training on hip density, muscle strength, and postural control in postmenopausal women: a randomized controlled ... frequencies and dumping factors depended on subject In Figure is presented an example of the mechanical behaviour of the three examined muscles, over the frequency range of interest, for one subject and...
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Báo cáo khoa học:

Báo cáo khoa học: "The radioprotective effects of the hexane and ethyl acetate extracts of Callophyllis japonica in mice that undergo whole body irradiation" pps

Báo cáo khoa học

... effects of irradiation The number of intestinal crypts is generally accepted as a good indicator of the protection of intestinal stem cells and/ or the proliferation of surviving cells in animals ... Vijayalaxmi Protective effects of melatonin against oxidation of guanine bases in DNA and decreased microsomal membrane fluidity in rat liver induced by whole body ionizing radiation Mol Cell Biochem ... ionizing radiation-induced apoptosis and stem cells in the small and large intestine Br J Cancer 1998, 78, 993-1003 12 Schuchter LM Guidelines for the administration of amifostine Semin Oncol 1996,...
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báo cáo khoa học:

báo cáo khoa học: " Simultaneous detection of Human Immunodeficiency Virus 1 and Hepatitis B virus infections using a dual-label time-resolved fluorometric assay" potx

Báo cáo khoa học

... assay was performed using serial dilutions (as a surrogate for a range of known concentrations) of an anti-HIV-1 antibody-containing serum sample in the absence and presence of the HBsAg binders, ... detect each of the two analytes (anti-HIV-1 antibody and HBsAg) in the absence (single-label) and presence (dual-label) of the binders of the other analyte Using rHBsAg (subtype adw), ranging from ... demonstrates in principle, the feasibility of developing a multiplex assay for screening samples for multiple infections in a blood bank setting However, a limitation is the potential for interference...
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Báo cáo khoa hoc:

Báo cáo khoa hoc:" Whole-body isometric force/torque measurements for functional assessment in neuro-rehabilitation: platform design, development and verification" docx

Báo cáo khoa học

... Journal of NeuroEngineering and Rehabilitation 2009, 6:38 Background One of the main scientific and technological challenges of rehabilitation bioengineering is the development of innovative ... daily instruments most widely used in the routine clinical practice In this work, our interest is focused on the development of mechatronic platform for the assessment of stroke patients using force/torque ... for days after 'Drinking': normalstroke onset (middle) hemiparetic patient, Force measurements fromsubject (top) ;and 131the task Force measurements from the index finger, for the task 'Drinking':...
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Báo cáo khoa học:

Báo cáo khoa học: " Inhibition of Tomato Yellow Leaf Curl Virus (TYLCV) using whey proteins" doc

Báo cáo khoa học

... Antiviral activity of Lactoferrin Antiviral activity of lactoferrin on infected tomato plants treated with: A) native lactoferrin, B) modified lactoferrin (5 plants for each treatment) 1) Before ... a-lactalbumin (97.46% protein), b-lactoglobulin (97.8% protein) were kindly obtained from Davisco food international (USA) and lactoferrine (95% protein) were kindly obtained from Armor Proteins (France) ... b-lactoglobulin More studies are needed to improve the antiviral activity of both of a-lactalbumin and b-lactoglobulin In future experiments, we will examine combined regimen of alternating milk-based and...
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Báo cáo y học:

Báo cáo y học: "What do measurements of molecular biomarkers in different body fluids really tell us" doc

Báo cáo khoa học

... synthesis and degradation can provide valuable additional information [5,6] Earlier work by Kraus and colleagues pointed to the importance of relating measurements in SF to urea to correct for dilutions ... exploratory/assessment phase in our understanding of what molecular biomarkers can really offer us We have often seen that measurements in sera or urine may have no relationship to events measured in joints The study ... sobering insights and reminders – we should exercise great caution in how we interpret biomarker data, and should endeavour to make sure we understand what the data mean Until we have definitive indications...
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