... increasing the running speed and time as follows: day 1, 10 minutes at 10 m/ min; day 2, 15 minutes at 12 m/ min; day 3, 20 minutes at 15 m/ min; day 4, 30 minutes at 18 m/ min; and day 5, 35 minutes ... 20 m/ min On day and thereafter, the rats were forced to run for 55 minutes a day at 20 m/ min, with the first 10 minutes consisting of a 12 m/ min warm-up Rats ran 30 km in weeks, as shown in Figure ... carried out the animal experiments, analyzed the results, and drafted the manuscript TMu designed the initial plan YJJ, AN, and TMo assisted inthe animal experiments KM and HM examined the keratan...
... restriction intheearly stage, and expression of E5 is nearly not detectable in all late stages for integration [3] Moreover, the ability of E6 and E7 to transform various cells have been demonstrated ... Gao Q, Dalal S, Hong Y, Mansur CP, Band V, Androphy EJ: Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells J Virol 1999, 73:7297-7307 ... Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes J Virol 2001, 75:7712-7716 Duensing S, Duensing A, Crum...
... conceal the onset and symptoms of CIP and may delay the diagnosis of CIP Therefore, electrophysiological examination is the most important tool intheearly diagnosis and course of CIP [2,13] But the ... aminoglycosides and their metabolites, are said to be the other factors responsible for development of CIP that results from the increase of capillary membrane permeability andthe invasion of ... Evidence of neuromuscular dysfunction intheearly stages ofthe systemic inflammatory response syndrome Intensive Care Med 2000, 26:1179-1180 23 Milner-Brown HS, Miller RG: Muscle membrane excitation...
... thickness The inner and outer internal elastic laminas were clear and intact inthe normal group The nucleus of endothelial cells was blue and arranged regularly, andthe nucleus of smooth muscle cells ... clear and intact; endothelia and smooth muscle cells (arrow) arranged regularly In panel B, the elastic lamina was incomplete and neointima was exposed Numerous smooth muscle cells near the internal ... smooth muscle cellsandthe internal elastic lamina was intact (Fig.1) http://www.medsci.org Int J Med Sci 2010, Immunocytochemistry The relatively low expression of Cx43 and Cx40 in VSMCs and...
... sheep-raising and wood-making industries They had to join the force of cheap labor and working in such factories England became a typical example of initial accumulation of capitalism Holding power in ... proud of their status in society andinthe superiority of their race They wanted other countries to give way to English men Therefore, they implemented many brutal and unjust wars In fact, the ... was a major conflict inthe begining of his isolation on the island, Robinson Crusoe was able to overcome it and maintain a very successful way of obtaining food Among such hardships emerged...
... Follistatin, Chordin and Noggin [12] These proteins are antagonists of BMP and other members ofthe TGF-b family, binding to and inhibiting these signaling molecules from binding to their receptors in ... knowledge, mostly about the function of genes andthe relationships among them, is being accumulated Members ofthe BMP family in zebrafish The roles of BMP proteins in mesoderm induction and dorsoventral ... by morpholino injections into embryos result in mild dorsalizations, andof these three BMP proteins, BMP4 seems to be the most effective [2] Members ofthe zebrafish BMP family involved in early...
... blotting Total RNA was extracted using RNeasy Mini Kit protocol A 5-mL culture in minimal medium, supplemented with all amino acids [8] andthe appropriate antibiotic, was induced with mm IPTG ... experiments MB01 cells with a pCMS71 derived plasmid (Fig 1) were grown overnight at 30 °C in M9 medium supplemented with all the amino acids at recommended concentration with and 100 lgÆmL)1 ampicillin ... assays and growth conditions Transformants were grown overnight at 37 °C in minimal medium [45] supplemented with all amino acids at recommended concentrations [8] and 100 lgÆmL)1 ampicillin These...
... discussion ofthe complex of associations summed up by the word atheism’ brings out the implications of such accusations,⁸⁵ andinthe introduction to a volume on early modern atheism he and David ... accuses them of ‘insolence and raillery’ claiming ‘they are serving the ends ofthe Atheists and are much supported by them’.⁷⁰ The criticisms made against Archbishop Tenison himself can be seen in ... transformation of social being.¹⁴ My interest in a particular intellectual debate, and specifically inthe much-decried materialism up to and including the French variety, might seem to be swimming...
... Thomas 1981, 40; Runciman 1990) More often than not, the turning point ofthe loss of autonomy and, hence, the beginning ofthe end ofthe polis, is placed either at the battle of Chaironeia in ... was inthe hands of an orthodox emperor Before that time the various accidents of war and commerce might indeed diffuse an imperfect knowledge ofthe Gospel among the tribes of Caledonia and among ... According to Nock: The success of Christianity is the success of an institution which united the sacramentalism andthe philosophy ofthe time It satisfied the inquiring turn of mind, the desire...
... craft, of a thousand tons burden or more, with the appearance and some ofthe armament of a 74-gun man -of- war Each year inthe winter or early spring a score of them left the Thames, some sailing ... namely, to command from the center, elevate the community above the individual, and allow nothing to undermine or break the harmony ofthe common course, the second moves in quite the opposite ... blazing fire in midsummer And both endured torments ofthe mind andofthe feelings: extreme nervousness, fits of uncontrollable weeping, fear, shame, anger, and dreadful nightmares "I recommend...
... (gasping) and to determine whether hypoxia results in changes inthe timefrequency patterns ofthe respiratory motor output We have examined the phrenic neurogram in both time and frequency domains ... rhythmic augmenting discharge of individual phrenic motorneurons resulting from an augmenting drive of supraspinal origin Richardson and Mitchell [24] compared the frequency spectra ofthe phrenic ... during eupnea andthe mean total energies below and above 150 Hz during gasping The mean ratio ofthe total energies above and below 150 Hz for theearlyand late phases ofthe phrenic neurogram...
... too early to comment on the clinical outcomes of these prostheses, the main determinants of success in these patients are pain relief and return to their normal physical function One ofthe main ... component in cases but the cup was grossly loose in only one of these There was evidence of gross collapse of a segment ofthe femoral head (evidenced by softening ofthe bone at the margin ofthe ... of hip resurfacing arthroplasty is an improved range of movement and stability ofthe large diameter bearing These should theoretically confer increased range of movement theoretically allowing...
... too early to comment on the clinical outcomes of these prostheses, the main determinants of success in these patients are pain relief and return to their normal physical function One ofthe main ... component in cases but the cup was grossly loose in only one of these There was evidence of gross collapse of a segment ofthe femoral head (evidenced by softening ofthe bone at the margin ofthe ... of hip resurfacing arthroplasty is an improved range of movement and stability ofthe large diameter bearing These should theoretically confer increased range of movement theoretically allowing...
... drill ofthe inner diameter 80 mm andthe length ofthe hollow part 200 mm in two steps, 0–20 cm and 20–40 cm The depth ofthe samples depended on the skeleton fraction and ranged from minimum 20 ... epidermal cells with the dominant function of water and minerals supply The ratio between the fine root length andthe number of root tips is an indicator ofthe intensity ofthe fine root forking ... plot the highest values ofthe fine root length were recorded inthe first mineral soil layer (0–10 cm) The maximum lengths were found inthe soil layer 0–5 cm on sample plots 1, and 4, andin the...
... similar among the four groups (piperacillin-tazobactam 56 (ranges: 13 to 164) mL/min; meropenem 64 (22 to 134) mL/min; ceftazidime 58 (15 to 145) mL/min; cefepime 40 (13 to 150) mL/min) In patients ... aeruginosa (% T > × MIC): 32 μg/mL or more (ceftazidime, cefepime), 64 μg/mL or more (piperacillin-tazobactam), and μg/mL or more (meropenem) Finally, by simulation using the PK parameters of our population, ... (depending on the frequency of administration ofthe β-lactam) thereafter; these blood-draw time points were chosen as they belong to the elimination phase of all four antibiotics The exact sampling...
... commences nematodes molt and pass through two more juvenile stages (J3, J4) and, after a final molt, develop into adults The enlarging body ofthe female, which remains sedentary for the remainder ... contig sequences in six frames and then ran its suite of domain-finding tools We required a minimum translation length of 20 amino acids to be considered by InterProScan, and we used the EGC.0 translation ... stageand q values for each tested combination of life stages as described in Materials and methods 17 The formostprobesetspatternline cycle their and methodselegans Additionalcycleover bymembershipinfJ2,...
... funding support, and Binna Choi and Heidi Arbuckle for their encouragement and time The Tropenmuseum Amsterdam, KITLV Leiden, Netherlands Photo Museum Rotterdam and Rijkmuseum Amsterdam, The Southeast ... photographic material found in other museums and archives inthe Netherlands, namely KITLV (The Royal Netherlands Institute of Southeast Asian and Caribbean Studies) in Leiden, The Wereldmuseum andThe ... andthe sugar industry was exemplary of this effort Simultaneously, following the economic success inthe Indies, more and more people from the Netherlands and Europe came to visit and some of...
... reveals the significance andthe role of women inthe competition of power between families Tony Day examines the importance of families for understanding the histories of states in pre-modern Southeast ... authority and dignity ofthe king include the Coronation Ritual, the Oath-Taking Ceremony, the Royal Procession on land and by boat, the drinking ofthe Water of Allegiance, andthe Ceremony ofthe ... exactly the same thing, since the Hindu concept of dharma differs from the Buddhist concept of dhamma/thamma In this dissertation, the terms Dharmasastra is used for the Hindu version, Thammasat...
... al., 1990) The mesenchymal layer is the middle layer surrounding the epithelium, and consists mainly of innervated smooth muscle The mesenchyme is involved in autonomous reabsorption and gas secretion ... (Finney et al., 2006) The outermost layer, the mesothelium, covers the mesenchyme and separates swimbladder tissue from the lumen The mesothelium contains pigments and guanine deposits that make ... Effects of temporal inhibition of wnt signaling on the epithelium development of swimbladder Effects of temporal inhibition of Wnt signaling on swimbladder mesenchyme and smooth muscles Effects of...