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Development of gold nanoparticle DNA nanostructure assembly for detection of DNA, RNA and protein biomarkers

Development of gold nanoparticle DNA nanostructure assembly for detection of DNA, RNA and protein biomarkers

Kỹ thuật - Công nghệ

... the AuNPs, as well as stabilized the products against uncontrolled aggregation [57] Examples of strong capping agents include thiol-based moieties such as mercapto acid [58], while compounds such ... much shorter than the EM waves LSPR is especially commonly observed for AuNPs, giving rise to strong light absorption at characteristic wavelengths For example, Link and El-Sayed found that the ... This is ideally suited for aggregationbased detections since the increased particle size yields a stronger signal [76] This also makes the light scattering detection systems far more sensitive than...
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Báo cáo y học:

Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"

Y học thưởng thức

... (intensity) of each protein (ion) WCX magnetic beads could capture more proteins in serum than strong anionic exchange magnetic beads, especially in the low molecular weight range It has been ... KR, Amneus MW, Pusey SM, Su F, Luong MN Identification of biomarkers for ovarian cancer using strong anion-exchange ProteinChips: potential use in diagnosis and prognosi Proc.Natl.Acad.Sci.USA.2003;...
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Tài liệu Báo cáo khoa học: Identification of Ewing’s sarcoma protein as a G-quadruplex DNA- and RNA-binding protein ppt

Tài liệu Báo cáo khoa học: Identification of Ewing’s sarcoma protein as a G-quadruplex DNA- and RNA-binding protein ppt

Báo cáo khoa học

... showed a strong positive band at 290 nm and a negative band at around 235 nm, whereas the addition of ratio excess of RGG3 led to an increase in ellipticity and shifted the spectrum from a strong...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "A HARDWARE ALGORITHM FOR HIGH SPEED MORPHEME EXTRACTION AND ITS IMPLEMENTATION" pptx

Báo cáo khoa học

... of the morphological analysis process time in conventional Japanese parsing systems, proves the strong requirement for the speed-up The second reason is that the morpheme extraction process is...
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Báo cáo khoa học: Glutamic acid residues in the C-terminal extension of small heat shock protein 25 are critical for structural and functional integrity pptx

Báo cáo khoa học: Glutamic acid residues in the C-terminal extension of small heat shock protein 25 are critical for structural and functional integrity pptx

Báo cáo khoa học

... binding fluorescence spectroscopy of wild-type and mutant Hsp25 Tryptophan fluorescence depends strongly on the local environment of the amino acid and is a sensitive probe of conformation in the ... italic type Dimethylsulfoxide was added to a final concentration of 5% (v ⁄ v) to reactions in which strong secondary interactions were likely, as advised by the supplier Successful mutagenesis was...
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Báo cáo khoa học: A new molecular tool for transgenic diatoms Control of mRNA and protein biosynthesis by an inducible promoter–terminator cassette docx

Báo cáo khoa học: A new molecular tool for transgenic diatoms Control of mRNA and protein biosynthesis by an inducible promoter–terminator cassette docx

Báo cáo khoa học

... (encoding ammonium transporter proteins) and NAT (encoding nitrate transporter proteins) genes becomes strongly up-regulated when cells are transferred from ammonium medium to –N medium [28,29], suggesting...
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Báo cáo khoa học: The 3¢-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing factors HuD and HuR ppt

Báo cáo khoa học: The 3¢-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing factors HuD and HuR ppt

Báo cáo khoa học

... performed RNase/EMSA analyses with 10 3¢ truncated MARCKS 3¢-UTR transcripts (data not shown) Strong RNA:protein complexes were only observed with RNA containing sequences between nucleotides ... treated with RNase A and resolved by electrophoresis on a 12.5% (w/v) SDS-polyacrylamide gel Four strong bands resulting from proteins crosslinked with the radioactively labeled RNA were detected ... sense DNA-oligonucleotide Addition of 10 ng and more of the 52 nt sense DNA-oligo resulted in a strong competition with the radioactive RNA for proteins and consequently a decrease in detection...
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Báo cáo khoa học:

Báo cáo khoa học: "A Framework for Unifying Named Entity Recognition and Disambiguation Extraction Tools" pot

Báo cáo khoa học

... AlchemyAPI has strong ability to recognize Person and City while obtaining significant scores for Organization and Country OpenCalais shows good results to recognize the class Person and a strong ability...
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Báo cáo khoa học: Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation pdf

Báo cáo khoa học: Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation pdf

Báo cáo khoa học

... Inactivation of FVa by APC Gla domain variants The inactivation of FVa on phospholipids by APC is strongly dependent on APC binding to anionic phospholipids Therefore, to indirectly assess APC variant...
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Báo cáo khoa học:

Báo cáo khoa học: "Toolkit for Multi-Level Alignment and Information Extraction from Comparable Corpora" pptx

Báo cáo khoa học

... being parallel, strongly comparable, or weakly comparable The evaluation results suggest that the comparability scores reliably reflect comparability levels In addition, there is a strong correlation ... comparability levels of comparable document pairs The evaluation on the gold standard shows a strong correlation (between 0.883 and 0.999) between human defined comparability levels and the confidence ... the relative positions of source and target aligned words differ;  a score indicating whether strong content word translations are found at the beginning and the end of each sentence in the given...
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