... 2008 FEBS 134 3 bp ofthe upstream region ofthe pri-miR9-1 fromhuman genomic DNA was cloned and fused into a pro-moterless reporter vector, pGL3_Basic, which contained the ORF ofthe FLuc reporter ... and 9 -3. Arrows indicate the positionand orientation ofthe primers. Bold fontrepresents the sequence of mature miR9*and italic fonts the sequence of maturemiR9. (C) RT-PCR analysis of pri-miR9s ... vector. The pro-moter sizes ofthe construct are indicatedby numbers in parentheses. )44 meanslocated 44 bp upstream ofthe rst base pairat the 5Â-end of pre-miR-9-1 dened as +1.FLuc is the...
... affecting the activity of ricin A chain (Eur. J. Biochem. 271) 157 involved the modification of arginyl residues 196, 2 13, 234 and 235 [9]. Of theses residues, only Arg2 13 is in the vicinity ofthe ... density of RTA R213D in the vicinity of residue 2 13. The backbone and sidechains ofthe R213D substitution are shown as stereoimages in thick ball and stick and the position ofthe Arg2 13 side-chain ... FEBS 20 03 doi:10.1046/j.1 432 -1 033 .20 03. 039 14.x models were based on the tetraloop structure of such ahexanucleotide, where the conformation ofthe targetadenine had been altered, using the known...
... varies from 100 to 30 00m. They distributed parallel to the shore in the form of bows with a distance from each other about 3- 10km. They are evidences of paleocoast existence during delta progradation ... facies model of an incided valley fill: The Gironde estuary, France. Journal of sedimentary Petrology 3 (19 93) 37 8. [3] Nguyen Huy Dung, 20 03, Report of Project “Division, correlation of Neogen-Quaternary ... weathering crust (Q13b) to be formed. These deposits are spread from the land to -100m water depth on the shelf. The colorful clays contain a lot of laterites nodules likes texture of...
... between the projection ofthe tilt ofthe z axis on the xÂ,y plane (dened direction of tilt of z and the x axis), and j % a + c denes the location ofthe rhombic (x, y) axes. The orientation ofthe ... 8.21CaH 3. 16 4 .31 CbH 2.16 3. 01, 3. 31CdHs 6.19 7 .39 CeHs 4.95 7.46CfH 4 .38 7.90Met1 43( H19) NH 7.49 7.89CaH 4.49 3. 64CbHs 2.28 0.98, 1 .34 CcH 1. 93 1.71CeH 3 0.48 1.27Ile147(H 23) ... stability of Pe Hb relative to other more autoxidizable globins. Areliable indicator ofthe dynamic stability of distal hemepockets in globins is the rate of reorientation ofthe aromatic rings in the...
... affected the level ofthe mRNAfor the other ADAM, confirming the specificity of theseASOs [19]. The ASOs reduced the level of their respectiveproteins in cell lysates but had little effect on the otherprotein ... 695–7 13 2217.4 2217.8 2217.2 34 751–764 1868.0 1867.9 1868.1 43 972–1001 30 75.5 30 76 .3 3076.144 1002–1025 2695.0 2696 .3 2695.047 1055–1067 1766.9 1766.9 1767 .3 51 1 133 –11 43 1176.4 1176 .3 1175.6 53 ... IC50 of 80 nM[14], we considered whether the APMA-induced shedding of ACE was mediated by TACE. The effect ofthe TACE ASO, along with the ADAM10ASO, on the APMA-induced shedding of ACE wastherefore...
... wake at 6 a.m., but nap for two hours or so in the early afternoon. Thus the influence on one's sleep pattern is worthy of consideration when choosing an occupation. ...
... however, the inequality becomes even more pronounced. In families of 1 - 2 children, men maintain approximately the same number of hours of unpaid work as in childless households, but the number of ... to work even fewer hours around the house than before the appearance ofthe third child. Whereas women's unpaid hours rise to approximately 56 per week, the corresponding figure for men, ... actually represents a decrease. The data suggest that the increased presence of women in the paid work force has yet to lead to an increased role for men in the home. ...
... product, then adjustments will have to be made to the product's design. Similarly, market research, which examines the extent and nature ofthe demand for products, has the role of guiding ... not only the result of product research, but is also influenced by testing and market research. If the testing stage (after assembly and inspection) reveals unacceptable problems in the finished ... serves to foster future sales by devising suitable advertising for the goods. Thus the reality of consumer goods manufacturing goes well beyond a simple linear production process. ...
... engineering: prospects for gene therapy. Gene Ther. 2002; 9(11):7 13- 718. 85. Lipps HJ, Jenke ACW, Nehlsen K, et al. Chromosome-based vectors for gene therapy. Gene Ther. 20 03; 30 4: 23- 33. 86. ... contributed to the embryo, the resultant offspring will be chimeric (up to ca. 50% of animals). The ESC contribution to a mouse can high (up to ca. 80% ofthe cells), and will often include the germline ... from the European Society of Gene Therapy (ESGT). J Gene Med. 20 03; 5(1):82-84. 30 . Fox JL. US authorities uphold suspension of SCID gene therapy. Nat Biotechnol. 20 03; 21 (3) :217-217. 31 . Chan...