... conferred with members ofthe board relative to the government's position. Late in the day the board was reported to be awaiting a report from a meeting of the directorate ofthe New York ... requirements upon security loans. This move was announced at midday atthe time ofthe first meeting ofthe banking group. According to the announcement the institutions participating in the ... Situation Members ofthe board, while admitting that the market situation was under discussion, declared atthe end ofthe day that there was no change which called upon the board for action relative...
... introduced the novelelement of real-time characterization of events by the team at the moment of consultation. This methodology captures importantopportunities for improvements in local care at a rate ... medical emergency teams (METs), knownwidely in North America as rapid response teams, mayprovide just such a method. The rationale for the development of METs rose from observations that, in the ... [4,5]. All of these detection methodsrequire substantial investments of time and money. Moreover,especially in the case of chart review, missing information oftenlimits the ability of reviewers...
... by treatment. RT-PCR and Western blot assay showed that the mRNA and protein expression of Cx40 and Cx43 were elevated in the neointimal area atthe early stage of atherosclerosis. The mRNA ... involved in the injury or dis-ease induced activation of vessel wall cells. It is indi-cated that the expression of Cx43 in the smooth mus-cle cells was markedly elevated atthe early stage of coronary ... the normal group. Vessel wall is in the condition of rugosity and the yellow athero-matous plaques were found in the lumens of high fat diet group. However, the vessel wall was expanded to different...
... if they flout them. THE A–Z OF MEDICAL WRITING34AtoZtext.qxd 22/02/00 13:52 Page 34format? Is there an example ofthe kind of conference report theylike (and perhaps one they don’t)?• At ... out ofthe mundane. Atthe same time try to makesense of it all. What’s new? What’s interesting? What would the readers like to hear about?• After the conference, decide on a message. Lack of ... mountains, theyare there. Some of us cannot resist the challenge; but it’s hardlyrational behaviour.Books, writing of chapters inOne ofthe great advan-tages of multi-authored books is that they meet...
... Application Contexts• Characterization Issue• Computation Issue• Duality• OrganizationCOMPUTATION PROBLEM• Iterative descent• Approximation• Role of convergence analysis• Role of rate of ... convergence of steep-est descentx0x1x2f(x) = c1f(x) = c3 < c2f(x) = c2 < c1...Quadratic Approximation of f at x0Quadratic Approximation of f at x1Fast convergence of New-ton’s ... where {dk} is gradientrelated. Assume that for some constant L>0,we have∇f(x) −∇f(y)≤Lx − y, ∀ x, y ∈n,Assume that either(1) there exists a scalar such that for all k0 <≤ αk≤(2...
... within the GBD part of the protein. Another possible explanation for the observedautoinhibitory activity is that the Hth domain mediatessome intramolecular interaction, or affects the confor-mation ... 7C, the Meis3.2 variant represented 25% of the total Meis3 message in most human cell lines tested. In the prostate cancer metastasis-derived cell line LNCaP, the majority ofthe Meis3 was Meis3.2, ... basesshaded black. The asterisk indicates the base that correlates with alternative or constitutive splicing. (B) The presence of alternative splicingaround the 5¢-end of exon 6 of Meis2 and Meis3 was...
... reportedthat, in Drosophila, the function ofthe nuage might berelated to the protection ofthe genome via repression of the selfish genetic elements in the female germ line[3]. The nuage is ... localization and to mea-sure the mobility ofthe components in the PGCs. The medaka embryo was peeled off the chorion, and the segment containing the part of PGCs was excised forobservation by microscopy ... Lateral plate mesoderm 0 min 1 min 2 min 3 min 4 min 9 min BAFig. 2. Time-lapse LSM analysis of Olvas–GFP reveals the dynamicnature ofthe nuage. Schematic diagram ofthe preparation of...
... site of E1, atthe bottom of which lies the ThDP cofactor some 20–25 A˚from the protein ÔsurfaceÕ[14]. Thus it may be that these mutations are affecting the efficacy ofthe recognition ofthe ... affecting the ability of E1 to catalyse the reductive acetylation ofthe tethered lipoyldomain in the assembled PDH complex. It should be notedthat Tyr281 and Arg282 are located atthe mouth of the funnel-shaped ... estimatedto have a dissociation constant in the millimolar range orhigher despite the fact that the Kmis c. 20 lM[37,38].Another difference in the assays is the concentration of the substrate,...
... bullet-proof fashion that willstand the test of time. The second, and for the working mathematician the most important, aspect of proof is that the proof of a new theorem explainswhy the result ... convincing another mathe-matician that a given statement (the theorem) is true. Thus a proof can takemany different forms. The most traditional form of mathematical proof isthat it is a tightly ... we are able to acquaint the reader with the culture of mathematics: who mathematicians are, what they care about, andwhat they do. We also give indications of why mathematics is important, andwhy...
... following the change in ellipticity at 222 nm at a constant heating rate of 40 °CÆh)1. The midpoint ofthe transition (Tm) was deter-mined from the first derivative ofthe smoothed denatur-ation ... with the Hill and Michaelis–Menten equations. The reaction rates were measured from the linear part ofthe initial time-course.GST–hGK fluorescence measurementsITF measurements were performed ... hyper-insulinism of infancy [6–11]. Some ofthe mutationsgreatly reduce the binding affinity of MgATP2)[11,12], which is compatible with a direct interaction of these residues with the nucleotide at the...
... changes. The forward -looking statements regarding earnings contained in these materials were valid atthe time these materials were drafted. SQUARE ENIX GROUP assumes no obligation to update or ... forward -looking statements about the future performance of SQUARE ENIX GROUP. These statements are based on management's assumptions and beliefs in light of information available to it at the ... successful media mix strategy61807,000Second -Half Operating IncomeFirst- Half Operating IncomeSoul Eater(Millions of yen)5,1575,4265,2106,1805,0006,000First- Half Operating IncomeFirst-Half...
... thatthis residue could affect the FAD environment, modulating the catalyticrate ofthe enzyme. Finaly, L315 affects the enzyme kcat, although it is notlocated in the near vicinity ofthe ... they are situated at similar distancesfrom the hydroxyl ofthe docked substrate, they couldcooperate in facilitating the hydride transfer from sub-strate to FAD. The decrease of activity of ... (re)-face ofthe isoalloxazine ring of the FAD cofactor. This substrate location is shown inFig. 2A, which includes the 10 molecules of veratrylalcohol clustering together after docking. The putativesubstrate-binding...
... for EFAMA members for which data are available; (2) including funds of funds, except for France, Germany and Italy for which the funds of funds data areincluded in theother fund categories; ... halfof 2010. Long-term UCITS attracted EUR 87 billion during the first halfofthe year, down from net inflows of EUR 142 billion for the same period in 2010. This reduction reflects the change ... inflows of EUR 23 billion during the quarter. Overall, net inflows into UCITS amounted to EUR 48 billion during the first halfof 2011, slightly behind the EUR 55 billion recorded in the first half...
... for EFAMA members for which data are available; (2) including funds of funds, except for France, Germany and Italy for which the funds of funds data areincluded in theother fund categories; ... remained relatively flat in the second quarter to stand at EUR 5,951 billion at end June 2012. Nine countries recorded an increase in net assets of UCITS during the quarter. Ofthe large domiciles, ... net outflows from equity funds. Oftheother large domiciles, the UK attracted net inflows of EUR 800 million, whilst France and Germany registered net outflows of EUR 9 billion and EUR 1 billion...